Drugs and Addiction Science: NIDA Celebrates 50 Years of Research and Looks to the Future
American Journal of Psychiatry,Volume 181, Issue 5, Page 349-352, May 01, 2024. (Source: American Journal of Psychiatry)
Source: American Journal of Psychiatry - May 6, 2024 Category: Psychiatry Authors: Nora D. Volkow Source Type: research

Substance Use Disorders: Confronting Addiction From Prevention to Recovery
American Journal of Psychiatry,Volume 181, Issue 5, Page 347-348, May 01, 2024. (Source: American Journal of Psychiatry)
Source: American Journal of Psychiatry - May 6, 2024 Category: Psychiatry Authors: Kathleen T. Brady Ned H. Kalin Source Type: research

A qualitative study of experiences with physical activity among people receiving opioid agonist therapy
Physical or mental health comorbidities are common among people with substance use disorders undergoing opioid agonist therapy. As both a preventive and treatment strategy, exercise offers various health benef... (Source: Substance Abuse Treatment, Prevention, and Policy)
Source: Substance Abuse Treatment, Prevention, and Policy - May 6, 2024 Category: Addiction Authors: Einar Furulund, Siv-Elin Leirv åg Carlsen, Karl Trygve Druckrey-Fiskaaen, Tesfaye Madebo, Lars T Fadnes and Torgeir Gilje Lid Tags: Research Source Type: research

Time for a Focus on Cessation of E-Cigarettes
E-cigarettes, which were introduced in the US market in 2007, have experienced tremendous growth in the US and globally and are the focus of an intense and often controversial public health debate concerning harms and benefits. The most important potential benefit of e-cigarettes is to assist with cigarette smoking cessation and reduce exposure to cigarette-related harm among those who completely switch to e-cigarettes. However, e-cigarettes can also produce harm and serve to initiate and maintain nicotine addiction in populations for whom there is no potential public health benefit of use. Indeed, e-cigarette use prevalen...
Source: JAMA Internal Medicine - May 6, 2024 Category: Internal Medicine Source Type: research

Individual Trajectories of Specialist Substance Use Disorder and Mental Health Treatment Utilization Among Young Adults With Substance Use Problems: A Cohort Study
CONCLUSIONS: Results demonstrated significant variation in trajectories of treatment use among young adults with substance use disorder. Differences in treatment use could indicate differences in symptom severity and complexity. In this study, treatment use was associated with socioeconomic factors, sex, and age. Integrative approaches, including interagency and interdisciplinary collaboration, will often be necessary to sufficiently address the multidimensionality of substance use disorder.PMID:38704859 | DOI:10.1080/15504263.2024.2341092 (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - May 5, 2024 Category: Addiction Authors: Regine Bakken J ūratė Š Benth Halvor Fauske Lars Lien Anne S Landheim Source Type: research

Nationwide Assessment of Chronic Pain among Hospitalized Individuals with Co-occurring Post Traumatic Stress Disorder and Substance Use Disorder in the United States
Conclusions: Among hospitalized Americans with co-occurring PTSD and SUD, advanced age, being female, and the presence other mental health disorders were associated with an increased risk of CP. Providers treating co-occurring PTSD/SUD should evaluate for and consider evidence-based management of CP if present.PMID:38704860 | DOI:10.1080/15504263.2024.2347489 (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - May 5, 2024 Category: Addiction Authors: Olaniyi Olayinka Brook T Alemu Stanley Nkemjika Declan T Barry Source Type: research

Individual Trajectories of Specialist Substance Use Disorder and Mental Health Treatment Utilization Among Young Adults With Substance Use Problems: A Cohort Study
CONCLUSIONS: Results demonstrated significant variation in trajectories of treatment use among young adults with substance use disorder. Differences in treatment use could indicate differences in symptom severity and complexity. In this study, treatment use was associated with socioeconomic factors, sex, and age. Integrative approaches, including interagency and interdisciplinary collaboration, will often be necessary to sufficiently address the multidimensionality of substance use disorder.PMID:38704859 | DOI:10.1080/15504263.2024.2341092 (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - May 5, 2024 Category: Addiction Authors: Regine Bakken J ūratė Š Benth Halvor Fauske Lars Lien Anne S Landheim Source Type: research

Nationwide Assessment of Chronic Pain among Hospitalized Individuals with Co-occurring Post Traumatic Stress Disorder and Substance Use Disorder in the United States
Conclusions: Among hospitalized Americans with co-occurring PTSD and SUD, advanced age, being female, and the presence other mental health disorders were associated with an increased risk of CP. Providers treating co-occurring PTSD/SUD should evaluate for and consider evidence-based management of CP if present.PMID:38704860 | DOI:10.1080/15504263.2024.2347489 (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - May 5, 2024 Category: Addiction Authors: Olaniyi Olayinka Brook T Alemu Stanley Nkemjika Declan T Barry Source Type: research

Non-oncogene dependencies: Novel opportunities for cancer therapy
Biochem Pharmacol. 2024 May 2:116254. doi: 10.1016/j.bcp.2024.116254. Online ahead of print.ABSTRACTTargeting oncogene addictions have changed the history of subsets of malignancies and continues to represent an excellent therapeutic opportunity. Nonetheless, alternative strategies are required to treat malignancies driven by undruggable oncogenes or loss of tumor suppressor genes and to overcome drug resistance also occurring in cancers addicted to actionable drivers. The discovery of non-oncogene addiction (NOA) uncovered novel therapeutically exploitable "Achilles' heels". NOA refers to genes/pathways not oncogenic per ...
Source: Biochemical Pharmacology - May 4, 2024 Category: Drugs & Pharmacology Authors: Tiziana Di Marco Mara Mazzoni Angela Greco Giuliana Cassinelli Source Type: research

Non-oncogene dependencies: Novel opportunities for cancer therapy
Biochem Pharmacol. 2024 May 2:116254. doi: 10.1016/j.bcp.2024.116254. Online ahead of print.ABSTRACTTargeting oncogene addictions have changed the history of subsets of malignancies and continues to represent an excellent therapeutic opportunity. Nonetheless, alternative strategies are required to treat malignancies driven by undruggable oncogenes or loss of tumor suppressor genes and to overcome drug resistance also occurring in cancers addicted to actionable drivers. The discovery of non-oncogene addiction (NOA) uncovered novel therapeutically exploitable "Achilles' heels". NOA refers to genes/pathways not oncogenic per ...
Source: Biochemical Pharmacology - May 4, 2024 Category: Drugs & Pharmacology Authors: Tiziana Di Marco Mara Mazzoni Angela Greco Giuliana Cassinelli Source Type: research

Hobbies, Distractions, Obsessions, and Addictions
A career in cardiothoracic surgery takes a psychological and emotional toll, which is likely increased by recent changes in our health care environment. The benefits of leisure pursuits are severalfold, one of which includes supporting physician wellness. However, we are at risk of relying on unhealthy mechanisms to provide relief. The incidence of addiction and substance abuse is high, particularly among women surgeons. There are a variety of opportunities to help ourselves and support our colleagues. We need to promote healthy activities outside of our profession for the long-term well-being of cardiothoracic surgeons an...
Source: Thoracic Surgery Clinics - May 4, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Shubham Gulati, M. Blair Marshall Source Type: research

Predictors of MOUD referral among persons with involvement in the criminal legal system
CONCLUSIONS: Data highlight the need for greater connection between referral agencies and MOUD treatment providers, considering factors that may influence referral.PMID:38700390 | DOI:10.5055/jom.0831 (Source: Journal of Opioid Management)
Source: Journal of Opioid Management - May 3, 2024 Category: Addiction Authors: Andrew P Bontemps Sofia Mildrum Chana Elizabeth S Hawes Yoser Al Rawi Christina E Cenczyk Lindsey R Atkins Li Li Karen L Cropsey Source Type: research

Opioid use and disposal at 2 weeks post-surgery: Brief communication regarding excess opioids and disposal habits
CONCLUSION: Two-thirds of the patients reported having excess opioids, highlighting the issue of an overabundance of unused prescription opioids in America. Utilization of opioid-free pain management strategies and drug disposal kits should be explored to reduce the number of unused and improperly disposed opioids.PMID:38700391 | DOI:10.5055/jom.0854 (Source: Journal of Opioid Management)
Source: Journal of Opioid Management - May 3, 2024 Category: Addiction Authors: Henry Kuechly Sarah Kurkowski John Bonamer Brian Newyear Brian Johnson Brian Grawe Source Type: research

Opioid prescribing patterns for distal radius fractures in the ambulatory setting: A 10-year retrospective study
CONCLUSIONS: Prescriptions of both opioid and nonopioid analgesic medications for DRF have been steadily increasing over time in the nonoperative ambulatory setting, with middle-aged adults most likely to receive an opioid prescription. Opioid prescription rates differ significantly between patients utilizing workers' compensation and patients receiving services under charity care, suggesting that socioeconomic factors play a role in prescribing patterns.PMID:38700392 | DOI:10.5055/jom.0862 (Source: Journal of Opioid Management)
Source: Journal of Opioid Management - May 3, 2024 Category: Addiction Authors: Brian Pettitt-Schieber Robert P Lesko Fei Wang Jinesh Shah Joseph A Ricci Source Type: research

United States marijuana legalization and opioid mortality trends before and during the first year of the COVID-19 pandemic
CONCLUSIONS: During the past decade, marijuana legalization in the US was associated at the jurisdiction level with a greater acceleration in opioid death rate. An even greater increase in opioid mortality occurred in recreational-legalizing jurisdictions with the onset of the COVID-19 pandemic. Marijuana legalization is correlated with worsening of the US opioid epidemic.PMID:38700393 | DOI:10.5055/jom.0829 (Source: Journal of Opioid Management)
Source: Journal of Opioid Management - May 3, 2024 Category: Addiction Authors: Archie Bleyer Brian Barnes Kenneth Finn Source Type: research