Psychiatrists can save lives with naloxone
CONCLUSIONS: Our findings highlight the importance of community access to naloxone in reducing opioid-related harm. Whilst removing the need for a prescription makes naloxone more accessible, it remains vital that doctors remain involved in this process to broaden the reach of supply to those at risk.PMID:38657130 | DOI:10.1177/10398562241249062 (Source: Australasian Psychiatry)
Source: Australasian Psychiatry - April 24, 2024 Category: Psychiatry Authors: Antigone Branchflower Robert M Lundin Craig Harvey Harry Hill Source Type: research

Psychiatrists can save lives with naloxone
CONCLUSIONS: Our findings highlight the importance of community access to naloxone in reducing opioid-related harm. Whilst removing the need for a prescription makes naloxone more accessible, it remains vital that doctors remain involved in this process to broaden the reach of supply to those at risk.PMID:38657130 | DOI:10.1177/10398562241249062 (Source: Australasian Psychiatry)
Source: Australasian Psychiatry - April 24, 2024 Category: Psychiatry Authors: Antigone Branchflower Robert M Lundin Craig Harvey Harry Hill Source Type: research

Psychiatrists can save lives with naloxone
CONCLUSIONS: Our findings highlight the importance of community access to naloxone in reducing opioid-related harm. Whilst removing the need for a prescription makes naloxone more accessible, it remains vital that doctors remain involved in this process to broaden the reach of supply to those at risk.PMID:38657130 | DOI:10.1177/10398562241249062 (Source: Australasian Psychiatry)
Source: Australasian Psychiatry - April 24, 2024 Category: Psychiatry Authors: Antigone Branchflower Robert M Lundin Craig Harvey Harry Hill Source Type: research

Psychiatrists can save lives with naloxone
CONCLUSIONS: Our findings highlight the importance of community access to naloxone in reducing opioid-related harm. Whilst removing the need for a prescription makes naloxone more accessible, it remains vital that doctors remain involved in this process to broaden the reach of supply to those at risk.PMID:38657130 | DOI:10.1177/10398562241249062 (Source: Australasian Psychiatry)
Source: Australasian Psychiatry - April 24, 2024 Category: Psychiatry Authors: Antigone Branchflower Robert M Lundin Craig Harvey Harry Hill Source Type: research

Examining within-person associations between alcohol and cannabis use and hooking up among adolescents and young adults in the United States
CONCLUSIONS: Given the significant daily-level associations between alcohol and cannabis use and hooking up behavior, public health initiatives should focus on developing interventions to reduce alcohol and cannabis use and promote safer hooking up behavior among adolescents and young adults.PMID:38657402 | DOI:10.1016/j.addbeh.2024.108040 (Source: Addictive Behaviors)
Source: Addictive Behaviors - April 24, 2024 Category: Addiction Authors: Melissa A Lewis Zhengyang Zhou Anne M Fairlie Dana M Litt Femke Geusens Kathleen A Parks Sean Esteban McCabe Source Type: research

Nicotine and Alcohol Use as Predictors of Recreational Cannabis Use in Adolescence: A Systematic Review and Narrative Synthesis
Conclusion: Current evidence suggests an association between nicotine-product use and subsequent recreational cannabis use among adolescents. However, further research is needed to establish causality between exposure to nicotine substances and the use of recreational cannabis within this age demographic. Additionally, there is a need for the development of prevention programs and targeted policies that continuously inform and update this vulnerable sub-population about the risks associated with cannabis use for leisure.PMID:38658323 | DOI:10.1080/10826084.2024.2342008 (Source: Substance Use and Misuse)
Source: Substance Use and Misuse - April 24, 2024 Category: Addiction Authors: T S Fingesi L J Kimaru B O Okusanya J E Ehiri C Rosales Source Type: research

Psychiatrists can save lives with naloxone
CONCLUSIONS: Our findings highlight the importance of community access to naloxone in reducing opioid-related harm. Whilst removing the need for a prescription makes naloxone more accessible, it remains vital that doctors remain involved in this process to broaden the reach of supply to those at risk.PMID:38657130 | DOI:10.1177/10398562241249062 (Source: Australasian Psychiatry)
Source: Australasian Psychiatry - April 24, 2024 Category: Psychiatry Authors: Antigone Branchflower Robert M Lundin Craig Harvey Harry Hill Source Type: research

Examining within-person associations between alcohol and cannabis use and hooking up among adolescents and young adults in the United States
CONCLUSIONS: Given the significant daily-level associations between alcohol and cannabis use and hooking up behavior, public health initiatives should focus on developing interventions to reduce alcohol and cannabis use and promote safer hooking up behavior among adolescents and young adults.PMID:38657402 | DOI:10.1016/j.addbeh.2024.108040 (Source: Addictive Behaviors)
Source: Addictive Behaviors - April 24, 2024 Category: Addiction Authors: Melissa A Lewis Zhengyang Zhou Anne M Fairlie Dana M Litt Femke Geusens Kathleen A Parks Sean Esteban McCabe Source Type: research

Correction: Characteristics and Risk of Adverse Mental Health Events Amongst Users of the National Overdose Response Service (NORS) Telephone Hotline
(Source: International Journal of Mental Health and Addiction)
Source: International Journal of Mental Health and Addiction - April 24, 2024 Category: Addiction Source Type: research

Development of the Modified Highly Processed Food Withdrawal Scale (mProWS)
Appetite. 2024 Apr 21:107370. doi: 10.1016/j.appet.2024.107370. Online ahead of print.ABSTRACTThe Highly Processed Food Withdrawal Scale (ProWS) is a 29-item measure that operationalizes physical and psychological indicators of withdrawal symptoms associated with cutting down on the consumption of ultra-processed foods. The current study developed a briefer 7-item version of the ProWS (modified ProWS; mProWS) using the participant sample from the ProWS validation paper (n = 231). Then, in an independent sample recruited from Amazon Mechanical Turk, 244 participants (55.3% females) completed the mProWS, the ProWS, and measu...
Source: Appetite - April 23, 2024 Category: Nutrition Authors: Shuchen Hu Ashley N Gearhardt Erica M LaFata Source Type: research

Reconsidering stepped wedge cluster randomized trial designs with implementation periods: Fewer sequences or the parallel-group design with baseline and implementation periods are potentially more efficient
CONCLUSION: If a three-sequence stepped wedge design with implementation periods is being considered for a future cluster randomized trial, then a corresponding modified design using only the first and last sequences should be considered if sole focus is on efficiency. However, a parallel-group design with baseline and implementation periods and analysis of covariance-based analysis can be a practical, efficient alternative. For stepped wedge designs with implementation periods and a larger number of sequences, modified versions that remove 'middle' sequences should be considered. Due to the potential sensitivity of design...
Source: Clinical Trials - April 23, 2024 Category: Research Authors: Philip M Westgate Shawn R Nigam Abigail B Shoben Source Type: research

Sports participation moderates the risk of family-specific negative life events on alcohol use among adolescents: Evidence from the longitudinal MyLife study
This study examined whether accumulated family-specific NLE in particular were associated with greater AU, and if so, whether SP moderated this association to reduce AU among high-NLE adolescents. We examined five annual assessments from a nationwide cohort of 3,422 Norwegian adolescents (13-15 year-olds; 55.3 % girls at baseline) who participated in the MyLife study. At each assessment, adolescents reported their AU on the Alcohol Use Disorders Identification Test-Concise (AUDIT-C), the number of family-specific NLE in the past 12 months, SP days in the past 30 days, and multiple sociodemographic and individual-level char...
Source: Addictive Behaviors - April 23, 2024 Category: Addiction Authors: Cagdas T ürkmen Geir Scott Brunborg Ingunn Olea Lund Falk Kiefer Sabine Vollst ädt-Klein Jasmina Burdzovic Andreas Source Type: research

Reconsidering stepped wedge cluster randomized trial designs with implementation periods: Fewer sequences or the parallel-group design with baseline and implementation periods are potentially more efficient
CONCLUSION: If a three-sequence stepped wedge design with implementation periods is being considered for a future cluster randomized trial, then a corresponding modified design using only the first and last sequences should be considered if sole focus is on efficiency. However, a parallel-group design with baseline and implementation periods and analysis of covariance-based analysis can be a practical, efficient alternative. For stepped wedge designs with implementation periods and a larger number of sequences, modified versions that remove 'middle' sequences should be considered. Due to the potential sensitivity of design...
Source: Clinical Trials - April 23, 2024 Category: Research Authors: Philip M Westgate Shawn R Nigam Abigail B Shoben Source Type: research

Development of the Modified Highly Processed Food Withdrawal Scale (mProWS)
Appetite. 2024 Apr 21:107370. doi: 10.1016/j.appet.2024.107370. Online ahead of print.ABSTRACTThe Highly Processed Food Withdrawal Scale (ProWS) is a 29-item measure that operationalizes physical and psychological indicators of withdrawal symptoms associated with cutting down on the consumption of ultra-processed foods. The current study developed a briefer 7-item version of the ProWS (modified ProWS; mProWS) using the participant sample from the ProWS validation paper (n = 231). Then, in an independent sample recruited from Amazon Mechanical Turk, 244 participants (55.3% females) completed the mProWS, the ProWS, and measu...
Source: Appetite - April 23, 2024 Category: Nutrition Authors: Shuchen Hu Ashley N Gearhardt Erica M LaFata Source Type: research

GSE246846 PML restrains p53 activity and cellular senescence in clear cell renal cell carcinoma
Contributors : Matilde Simoni ; Chiara Menegazzi ; Cristina Fracassi ; Claudia C Biffi ; Francesca Genova ; Nazario P Tenace ; Roberta Lucian ò ; Andrea Raimondi ; Carlo Tacchetti ; James Brugarolas ; Davide Mazza ; Rosa BernardiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensClear cell renal cell carcinoma (ccRCC), the major subtype of RCC, is frequently diagnosed at late/metastatic stage with 13% 5-year disease-free survival. Functional inactivation of the wild type p53 protein is implicated in ccRCC therapy resistance, but the detailed mechanisms of p53 malfunction are s...
Source: GEO: Gene Expression Omnibus - April 23, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research