Predictive Outcome Validity of General Health Questionnaire (GHQ-28) in Substance Abuse Patients Treated in Therapeutic Communities.
Conclusions: The results of this study support the notion that the probable psychiatric cases identified by the GHQ-28 scale have a greater probability of "early treatment dropout" and have a greater probability of "nonclinically relevant improvement in discharge" of the therapeutic community. These data indicate that GHQ-28 is a suitable clinical instrument for predicting dropout and treatment effect in residential substance use disorder treatment. PMID: 31608803 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - October 16, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Modeling the Comorbidity of Cannabis Abuse and Conduct Disorder/Conduct Problems from a Cognitive Neuroscience Perspective.
Conclusions: Based on the literature, a causal model of the comorbidity of cannabis abuse and CD/CP is developed. PMID: 31608811 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - October 16, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Cannabinoid Receptor Type 1 and Its Role as an Analgesic: An Opioid Alternative?
This article will review this evidence in the context of its implications for pain. We first provide a brief overview of CB1R's role in the regulation of nociception, followed by a review of the evidence that the peripheral endocannabinoid system modulates nociception. We then look in detail at regulation of central-mediated analgesia, followed up with evidence that cannabinoidmediated modulation of pain involves modulation of GABAergic and glutamatergic neurotransmission in key brain regions. Finally, we discuss cannabinoid action on non-neuronal cells in the context of inflammation and direct modulation of neurons. This ...
Source: Journal of Dual Diagnosis - October 10, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Interaction of Cannabis Use and Aging: From Molecule to Mind.
Authors: Yoo HB, DiMuzio J, Filbey FM Abstract Given the aging Baby Boomer generation, changes in cannabis legislation, and the growing acknowledgment of cannabis for its therapeutic potential, it is predicted that cannabis use in the older population will escalate. It is, therefore, important to determine the interaction between the effects of cannabis and aging. The aim of this report is to describe the link between cannabis use and the aging brain. Our review of the literature found few and inconsistent empirical studies that directly address the impact of cannabis use on the aging brain. However, research focus...
Source: Journal of Dual Diagnosis - October 3, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Measuring Personality Problems in Patients With Substance Use Disorders: A Cross-Sample Validation.
Conclusions: SIPP appears to be a promising instrument for assessing personality pathology in substance use disorder treatment. The finding of high levels of maladaptive personality functioning in substance use disorder populations challenges the clinical management of the substance use disorder patient group and supports the development of integrated treatment approaches. PMID: 31571533 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - October 3, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Patient Characteristics Predicting Abstinence in Substance Use Disorder Patients With Comorbid Mental Disorders.
Conclusions: The results indicate that being a first- or second-generation immigrant and experiencing more symptoms of depression and anxiety are predictive of non-abstinence. Attention for linguistic and cultural congruence of dual diagnosis treatments may enhance abstinence in immigrants. Additionally, addressing symptoms of depression and anxiety in dual diagnosis treatment may be beneficial for the maintenance of abstinence. More research is needed on factors influencing treatment success in dual diagnosis patients. PMID: 31566115 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - October 2, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Outcome of Patients With High Depressive Symptoms on Admission to Methadone Maintenance Treatment.
Authors: Malik E, Adelson M, Sason A, Schreiber S, Peles E Abstract Objective: Comorbidity of depression among individuals with opioid addiction is highly prevalent, but their outcome in methadone maintenance treatment (MMT) is not well determined. Methods: Characteristics and outcomes (retention until December 2017) of newly admitted and already (5.5 ± 4 years) in MMT patients with available Hamilton Depression Rating Scale (HAM-D) scores on admission were studied. Results: During psychiatric intake on admission, 70 (21.2%) of 330 patients were diagnosed with high depressive symptoms beyond th...
Source: Journal of Dual Diagnosis - September 20, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Use of Prescribed Psychotropic Medications in an Opioid Substitution Therapy Cohort.
Conclusions: This highlights the need for evidence-based treatment of comorbid mental illness for individuals receiving opioid substitution therapy. PMID: 31519141 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - September 16, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Exploring the Relationships Between Eating Disorders and Mental Health in Women Attending Residential Substance Use Treatment.
This study also examines past physical and sexual abuse and mental health as specific predictors of EDs/ED symptoms. Methods: Participants were 1,444 women attending residential treatment for substance use issues provided by the Salvation Army in Australia. Measures included the Addiction Severity Index, the Eating Disorder Screen for Primary Care, medication use, hospitalization, mental health, and past abuse. Results: Alcohol was the primary substance of concern for 53.3% of the women, followed by amphetamines (17.5%), and the mean age was 37.83 years (SD = 10.8). Nearly 60% of women screened positiv...
Source: Journal of Dual Diagnosis - September 16, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Exploring Cannabis and Alcohol Co-Use in Adolescents: A Narrative Review of the Evidence.
Conclusion: Variation in study methodologies, policy-level limitations and our limited understanding of the developmental neurobiological effects of cannabis preclude the straightforward interpretation of the existing data on adolescent cannabis and alcohol use. Further research on this topic is requisite to inform the development of effective intervention and prevention programs for adolescent substance users, which hinge on a more comprehensive understanding of how cannabis-and its intersection with alcohol-impacts the developing brain and behavior. PMID: 31519143 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - September 16, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Are Computer-Based Treatment Programs Effective at Reducing Symptoms of Substance Misuse and Mental Health Difficulties Within Adults? A Systematic Review.
Conclusions: Many papers were limited by high attrition rates commonly attributed to "digital" interventions. Future research should consider systematically recruiting a range of participants, including those potentially affected by the digital divide, and incorporating methods within research to maintain engagement. This review was also limited by the heterogeneity of the papers reported, many of which differed between targeting dual diagnosis and targeting either substance misuse or mental health respectively, with outcomes investigating other difficulties out of curiosity. PMID: 31476983 [PubMed - as suppl...
Source: Journal of Dual Diagnosis - September 5, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

The Effectiveness of Cannabinoids in the Treatment of Posttraumatic Stress Disorder (PTSD): A Systematic Review.
Conclusions: Most studies to date are small and of low quality, with significant limitations to the study designs precluding any clinical recommendations about its use in routine clinical practice. Evidence that cannabinoids may help reduce global PTSD symptoms, sleep disturbances, and nightmares indicates that future well-controlled, randomized, double-blind clinical trials are highly warranted. PROSPERO registration number: 121646. PMID: 31479625 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - September 5, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Cannabis and Epilepsy.
Authors: Doyle A, Harvey J Abstract Objective: In recent years, the use of cannabidiol in the treatment of refractory epilepsy has been increasingly investigated and has been gaining public support as a novel way to treat these disorders. Marijuana has been used for medical purposes for thousands of years, and a lot of research has been conducted over the last several decades into the chemistry and pharmacology of marijuana and its many compounds, including cannabidiol. Methods: Using PubMed, we performed a review of the literature regarding the history of cannabinoid use in treating epilepsy. Results and conclusio...
Source: Journal of Dual Diagnosis - August 7, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Public Perceptions of Recovery Prospects and Peer Style (Support and Confrontation) in Services for Serious Mental Illness Versus Substance Use Disorder.
Conclusions: These findings have potential implications for peers and their style in SMI and substance use disorder services as well as in the unique interventions for people with dual disorders. PMID: 31311451 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - July 18, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Cannabis Use in Adolescence: A Review of Neuroimaging Findings.
Conclusions: While there is some evidence of compromised frontoparietal structure and function in adolescent cannabis use, it remains unclear whether the observed effects are specifically attributable to adolescent onset of use or general cannabis use-related factors such as depressive symptoms. The relative contribution of adolescent onset of cannabis use and use chronicity will have to be more comprehensively examined in prospective, longitudinal studies with more rigorous measures of cannabis use (dosage, exposure, dependence, constituent compounds such as the relative cannabinoid levels). PMID: 31311489 [PubMed - a...
Source: Journal of Dual Diagnosis - July 18, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

PTSD Symptom Clusters and Craving Differs by Primary Drug of Choice.
Conclusions: Findings suggest that craving may play a role in maintaining the relationship between specific PTSD symptom clusters and substance use disorder, and the nature of this relationship may differ by primary DOC. The clinical trial on which this secondary analysis of data was conducted is registered as NCT01159535 at www.clinicaltrials.gov . The original trial from which data for this study was drawn was supported by the National Institutes of Health [NIH/NIDA 5 R01 DA025764-02]. PMID: 31304887 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - July 17, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Impact of Substance Use and Mental Health Comorbidity on Health Care Access in Canada.
Conclusions: Although the level of access to health care was low overall, those with concurrent disorders were more likely to access mental health services than those with substance use disorders or mental disorders only. The findings of this study reveal various treatment gaps, especially in those experiencing substance use disorders, and reaffirm the importance of improving treatment accessibility for these individuals. PMID: 31282295 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - July 11, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Sensorimotor Gating in Cocaine-Related Disorder with Comorbid Schizophrenia or Antisocial Personality Disorder.
Conclusions: The results suggest that the prepulse inhibition is a promising dual-diagnosis vulnerability marker in individuals with cocaine addiction, because prepulse inhibition deficits are related both to schizophrenia and antisocial personality disorder. In addition, prepulse inhibition, which is considered a good endophenotype for studies on the genetic and neurobiological basis of cocaine-related disorder and schizophrenia, could be used in the same way in studies on antisocial personality disorder. PMID: 31287382 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - July 11, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Health Care Processes Contributing to Suicide Risk in Veterans During and After Residential Substance Abuse Treatment.
Conclusions: Efforts to prevent suicide in the period following discharge from a residential drug treatment program should focus on addressing suicide risk factors during admission and helping patients engage more fully in substance use disorder treatment. PMID: 31253073 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - July 1, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Adverse Effects of Cannabis Use on Neurocognitive Functioning: A Systematic Review of Meta- Analytic Studies.
Conclusions: Meta-analyses have played an important role in helping to grasp the totality of results from a large body of literature on cannabis effects on neurocognition, yet more research (particularly large-scale longitudinal studies) is needed to identify critical periods or patterns of use that are more likely to result in negative outcomes. PMID: 31232216 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - June 25, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Electronic cigarette use during a randomized trial of interventions for smoking cessation among Medicaid beneficiaries with mental illness.
Conclusions: Spontaneous e-cigarette use during cessation treatment was common among smokers with mental illness and was not associated with positive or negative treatment outcomes. The high rate of naturalistic e-cigarette use in this group suggests that e-cigarettes are an appealing strategy to obtain nicotine during cessation treatment that could be harnessed as a smoking cessation tool or for harm reduction. PMID: 31169077 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - June 8, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Comorbidity of Physical Disorders Among Patients With Severe Mental Illness With and Without Substance Use Disorders: A Systematic Review and Meta-Analysis.
Conclusions: Physical disorders among SMI patients vary by substance use disorder status. Clinicians managing SMI in patients should screen for physical disorders and substance use disorders and provide treatment or referral. Registration: International Prospective Register of Systematic Reviews (PROSPERO) registration number CRD42017072286. PMID: 31164045 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - June 7, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Changes of Self-reported PTSD and Depression Symptoms During Alcohol Detoxification Treatment.
Authors: Ostergaard M, Seitz R, Jatzkowski L, Speidel S, Höcker W, Odenwald M Abstract Objective: There is a lack of empirical knowledge on how different comorbid disorders and symptoms change in the course of initial abstinence and withdrawal. The aim of this study is to replicate previous findings on the symptom course using a larger sample and up-to-date psychometric instruments. Methods: During inpatient alcohol detoxification, we measured comorbid depression (Beck Depression Inventory second revision; BDI-II) and posttraumatic stress disorder (PTSD Checklist for DSM-5; PCL-5) symptoms twice among 87 parti...
Source: Journal of Dual Diagnosis - June 5, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Discrepancies in the Validity of Self-reported Cigarette Smoking in Adults With and Without ADHD.
Conclusions: Individuals with ADHD and high school or lower education showed the lowest specificity and accuracy in their self-reported smoking, which may affect documented smoking prevalence rates. This is a secondary analysis of data collected as part of a clinical trial registered as NCT00915798 at www.clinicaltrials.gov . PMID: 31156069 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - June 5, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Phenomenology and Course of Alcoholic Hallucinosis.
Conclusions: Alcoholic hallucinosis is an acute short-lasting psychotic disorder which lasts for less than a week when treated. Suicidality is high in this group, which needs attention. Benzodiazepines as part of withdrawal management may be sufficient for a majority of cases. Antipsychotics may be required in selected cases. A high degree of recurrence and morbidity indicates a need to intervene early with an abstinence-oriented management goal. PMID: 31161915 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - June 5, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Editorial.
Authors: Brown ES, Green A PMID: 31138080 [PubMed - in process] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - May 31, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Healthy Recovery: A Pilot Study of a Smoking and Other Health Behavior Change Intervention for People Attending Residential Alcohol and Other Substance Dependence Treatment.
Conclusions: Results from this study demonstrated that people attending residential substance dependence treatment are willing and capable of engaging in multiple health behavior change interventions. PMID: 31122158 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - May 29, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

The Severity of Personality Pathology: A Risk Factor for Concurrent Substance Use Disorders in Alcohol Use Disorder.
Authors: Cavicchioli M, Prudenziati F, Movalli M, Ramella P, Maffei C Abstract OBJECTIVE: Co-occurrence of substance use disorders (CO-substance use disorders) among individuals with alcohol use disorder (AUD) is largely recognized as a critical clinical issue. However, the specific clinical variables involved are still unclear. The recent findings are controversial in pointing out the unique contribution of both impulsivity and emotion dysregulation on CO-substance use disorders. Furthermore, the co-variation between AUD and other substance use disorders includes different aspects of maladaptive personality functi...
Source: Journal of Dual Diagnosis - May 16, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Psychiatric Hospitalizations of Chronic Psychotic Disorder Patients With and Without Dual Diagnosis, Israel, 1963-2016.
This study examines, for the first time in Israel, the prevalence of DD and patterns of psychiatric hospitalizations of chronic psychotic disorder patients with and without substance use disorder. METHODS: The National Psychiatric Case Registry provided data on 18,684 persons with schizophrenia/schizoaffective disorders, aged 18-65, with a psychiatric hospitalization during the period 1963-2016 (with at least one hospitalization in 2010-15). Patients were considered as having DD if their substance use disorder was indicated in at least two, or 20%, of hospitalizations. Regression modeling predicted hospitalization meas...
Source: Journal of Dual Diagnosis - May 15, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

The mediating role of impulsivity between psychological distress and alcohol misuse among college students at a historically Black university.
CONCLUSIONS: These findings suggest the utility of targeting impulsivity in interventions aimed at preventing and reducing alcohol misuse among college students attending HBCUs who experience psychological distress. PMID: 31007151 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - April 24, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Comorbidity Patterns Among Patients With Opioid Use Disorder and Problem Gambling: ADHD Status Predicts Class Membership.
CONCLUSIONS: PrG patients seem to be at an even higher risk for psychiatric comorbidities compared to OMT patients. Raising awareness among practitioners for the high prevalence of psychiatric comorbidities among patients with gambling disorder and individuals with ADHD is crucial to initiate adequate treatment and to improve response. PMID: 30999811 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - April 21, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Predictive Associations Among the Repeated Measurements of Anxiety, Depression, and Craving in a Dual Diagnosis Program.
CONCLUSIONS: These preliminary findings support mutual maintenance models of substance use and psychiatric comorbidity, thus providing preliminary support for integrated programs that simultaneously address both problems. Implications and future directions are discussed. PMID: 30982462 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - April 16, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

The Role of Mental Health and Substance Use in Homeless Adults' Tobacco Use and Cessation Attempts.
CONCLUSIONS: Findings suggest that demographic and clinical characteristics associated with tobacco use differ among this sample of homeless adults and those identified by the CDC among housed adults. Mental health conditions and substance use appear to be the primary correlates of tobacco use among adults experiencing homelessness and may be critical in efforts aimed at improving cessation. PMID: 30940011 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - April 5, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

From the Editors: Brief Synopsis.
Authors: Green AI, Sherwood Brown E PMID: 30929587 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - April 2, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Living With Dual Diagnosis and Homelessness: Marginalized Within a Marginalized Group.
CONCLUSIONS: Within this marginalized group, individuals with dual diagnosis were more likely to be from groups considered to be more vulnerable with more complex needs. They were having more problems accessing even basic support, such as shelters and health care. Without a systematic approach in providing appropriate care to individuals with dual diagnosis, the most vulnerable clients are not only the ones likely to suffer the most but also the ones having the most problems meeting their basic needs. PMID: 30929588 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - April 2, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

From the Editors.
Authors: Green AI, Brown ES PMID: 30908171 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - March 26, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Heterogeneity in the Co-occurrence of Substance Use and Posttraumatic Stress Disorder: A Latent Class Analysis Approach.
CONCLUSIONS: Results provide construct validity support for three meaningful latent classes with unique relations with depression and RSDBs. These findings improve our understanding of heterogeneous PTSD-SU comorbidity patterns and highlight acknowledgment of such subtyping (subgrouping) in considering differential treatment options, treatment effectiveness, and resource allocation. PMID: 30838935 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - March 8, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Psychotic Decompensation During Nalmefene Treatment in a Patient With Schizoaffective Disorder: A Case Report.
CONCLUSIONS: This case indicates that the AEs of nalmefene should be specifically investigated in patients with psychiatric disorders. PMID: 30829564 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - March 6, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

A Review of Integrated Care for Concurrent Disorders: Cost Effectiveness and Clinical Outcomes.
CONCLUSIONS: Given the limited number of studies in relation to service delivery for concurrent disorders, it is too early to make a strong evidence-based recommendation to policy makers and service providers as to the superiority of one approach over the others. However, the available evidence suggests that integrated care models for concurrent disorders are the most effective models for patient care. More research is needed, especially around the translation of research findings to policy development and, vice versa, around the translation from the policy level to the patients' level. PMID: 30806190 [PubMed - as supp...
Source: Journal of Dual Diagnosis - February 27, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Field Test of a Dialectical Behavior Therapy Skills Training-Based Intervention for Smoking Cessation and Opioid Relapse Prevention in Methadone Treatment.
CONCLUSIONS: A DBT skills training-based intervention for individuals who smoke and have an opioid use disorder is feasible and acceptable in methadone treatment and may help this population prevent drug relapse, attempt to quit smoking, experience smoke-free days, and cut down on their smoking. More research is needed to determine the optimal structure and components of a DBT skills-based intervention for drug relapse prevention and smoking cessation. Further, a randomized controlled trial of DBT-Quit is needed to determine the efficacy of DBT skills training for smoking cessation and drug relapse prevention in this popul...
Source: Journal of Dual Diagnosis - January 18, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Precision Psychiatry and Dual Disorders.
CONCLUSIONS: Here we survey the discoveries, future research directions, and translational relevance of the concept of precision psychiatry for dual disorders. The review may offer new perspectives on this issue and highlight a new way to see and to think about dual disorders. PMID: 30638153 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - January 15, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

A Pilot Randomized, Placebo-Controlled Trial of Glycine for Treatment of Schizophrenia and Alcohol Dependence.
CONCLUSIONS: Although our study showed no beneficial effect of glycine over placebo, our results are consistent with the largest trial of glycine treatment in schizophrenia. Diagnosed schizophrenia and alcohol dependence might be more difficult to treat because of more severe psychopathology. This is the first study to date to examine an innovative treatment approach with an amino acid, glycine, as potentially acting on both alcohol intake and negative symptoms of schizophrenia. PMID: 30633660 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - January 13, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Permanent Supportive Housing and Specialized Co-Occurring Disorders Wraparound Services for Homeless Individuals.
CONCLUSIONS: This pilot study demonstrated that systematically integrating PSH and MISSION can improve access and engagement in care, housing retention, and mental health outcomes. Despite the preliminary success and while taking into account the limitations of the open single-group pre/post design, this study also identified the lack of affordable housing as a potential barrier to placement as well as the critical role of housing for improved clinical outcomes. Randomized controlled trials are needed to test MISSION with PSH as well as perhaps PSH with and without MISSION to tease apart the effects of integrating both app...
Source: Journal of Dual Diagnosis - January 7, 2019 Category: Addiction Tags: J Dual Diagn Source Type: research

Alcohol and Suicide Risk: Examining the Role of Meaning-Making.
CONCLUSIONS: Meaning-making did not appear to attenuate the effect of alcohol misuse on suicide risk severity in a sample of service members at high-risk of suicidality. Additional research is needed to better understand the relationship among meaning-making, alcohol misuse, and suicidal behavior. PMID: 30451598 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - November 21, 2018 Category: Addiction Tags: J Dual Diagn Source Type: research

Alcohol Use and Drinking Motives Among Suddenly Bereaved College Students.
CONCLUSIONS: Bereavement-related distress may influence drinking motives among young adults with a history of sudden loss. PMID: 30451601 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - November 21, 2018 Category: Addiction Tags: J Dual Diagn Source Type: research

Polysubstance Use Among Veterans in Intensive PTSD Programs: Association With Symptoms and Outcomes Following Treatment.
CONCLUSIONS: Polysubstance use, conceptualized within the multimorbidity perspective, is associated with increased severity of PTSD symptoms among veterans with dual diagnoses requiring complex interventions, the evaluation of which will require innovative trial designs. PMID: 30444189 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - November 18, 2018 Category: Addiction Tags: J Dual Diagn Source Type: research

Increased Connectivity Between the Nucleus Accumbens and the Default Mode Network in Patients With Schizophrenia During Cigarette Cravings.
CONCLUSIONS: These results highlight a key role of the nucleus accumbens in cigarette craving in schizophrenia and suggest that the subjective valuation of cigarette cues is increased in this population. Similar neurofunctional studies on cravings for other psychoactive substances in schizophrenia are warranted. PMID: 30445892 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - November 18, 2018 Category: Addiction Tags: J Dual Diagn Source Type: research

Posttraumatic Symptomatology and Alcohol Misuse Among Black College Students: Examining the Influence of Anxiety Sensitivity.
CONCLUSIONS: These findings suggest that the assessment of anxiety sensitivity may be useful in identifying trauma-exposed Black individuals who are likely to experience alcohol misuse and the clinical utility of addressing PTSS in this population reporting anxiety sensitivity to possibly prevent alcohol misuse and related negative consequences. PMID: 30421662 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - November 15, 2018 Category: Addiction Tags: J Dual Diagn Source Type: research

Resting Heart Rate Variability: Exploring Associations With Symptom Severity in Adults With Substance Use Disorders and Posttraumatic Stress.
CONCLUSIONS: HF-HRV may be more sensitive to the severity of drug and alcohol use rather than PTSD. Findings may suggest that in PTSD populations, HF-HRV may primarily index comorbid substance use disorder symptoms. HF-HRV could serve as an objective measure of substance use severity and should be further investigated as a predictor of outcomes in treatment for substance use disorders. PMID: 30418104 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - November 14, 2018 Category: Addiction Tags: J Dual Diagn Source Type: research

Psychiatric and Substance Use Comorbidity in Treatment-Seeking Injection Opioid Users Referred From Syringe Exchange.
CONCLUSIONS: Findings suggest the importance of evaluating and treating co-occurring psychiatric and substance use disorders in the treatment of injection drug users with opioid dependence. PMID: 30332349 [PubMed - as supplied by publisher] (Source: Journal of Dual Diagnosis)
Source: Journal of Dual Diagnosis - October 19, 2018 Category: Addiction Tags: J Dual Diagn Source Type: research