Acute Lymphoblastic Leukemia Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Differential activation of basal and IL-7-induced PI3K/Akt/mTOR and JAK/STAT5 signaling distinguishes pediatric from adult acute lymphoblastic leukemia
Haematologica. 2024 Apr 24. doi: 10.3324/haematol.2023.284102. Online ahead of print.ABSTRACTNot available.PMID:38654666 | DOI:10.3324/haematol.2023.284102 (Source: Haematologica)
Source: Haematologica - April 24, 2024 Category: Hematology Authors: Marta B Fernandes A Margarida Gomes Mariana L Oliveira Joana Caldas Paulo L úcio Rathana Kim Aur élie Caye-Eude Filomena Pereira Aida B De Sousa Alessia De Stefano Matilde Y Follo Maria V Soares Jo ão F Lacerda Joana Desterro H élène Cavé Emmanuelle Source Type: research

Work Disability and Return to Work After Treatment for Acute Lymphoblastic Leukemia: A Danish Nationwide Cohort Study [Letter]
(Source: Clinical Epidemiology)
Source: Clinical Epidemiology - April 24, 2024 Category: Epidemiology Tags: Clinical Epidemiology Source Type: research

Refined risk stratification helps guiding transplantation choice in adult BCR::ABL1-positive acute lymphoblastic leukemia
Blood Cancer Journal, Published online: 24 April 2024; doi:10.1038/s41408-024-01055-1Refined risk stratification helps guiding transplantation choice in adult BCR::ABL1-positive acute lymphoblastic leukemia (Source: Blood Cancer Journal)
Source: Blood Cancer Journal - April 24, 2024 Category: Hematology Authors: Cheng Wang Jianfeng Li Weiyang Liu Lingling Zhao Han Yan Yuchen Yan Jiayi Ren Lijun Peng Jiaojiao Zhang Yuanfang Liu Xiangqin Weng Yongmei Zhu Duohui Jing Jian-Qing Mi Jin Wang Source Type: research

Exercise and QUality diet After Leukemia (EQUAL): A randomized weight loss trial among adult survivors of childhood leukemia in the Childhood Cancer Survivor Study
CONCLUSIONS: A remote weight-loss intervention that was successful among adults with CV conditions did not result in significant weight loss among adult survivors of childhood ALL.IMPACT: Future interventions in this population must be tailored to the unique needs of survivors to encourage engagement and adherence.PMID:38652494 | DOI:10.1158/1055-9965.EPI-23-1601 (Source: Cancer Control)
Source: Cancer Control - April 23, 2024 Category: Cancer & Oncology Authors: Danielle Novetsky Friedman Joanne F Chou Jeanne M Clark Chaya S Moskowitz Jennifer S Ford Gregory T Armstrong Nidha Z Mubdi Aaron McDonald Paul C Nathan Charles A Sklar Lakshmi V Ramanathan Leslie L Robison Kevin C Oeffinger Emily S Tonorezos Source Type: research

Flow cytometric minimal residual disease measurement accounting for cytogenetics in children with non ‐high‐risk acute lymphoblastic leukemia treated according to the ALL‐MB 2008 protocol
ConclusionOur data show that combining clinical risk factors with MFC-MRD measurement is the most useful tool for risk group stratification of children with BCP-ALL in the reduced-intensity protocols. However, this algorithm can be supplemented with cytogenetic data for part of the ImR group. (Source: Cancer Medicine)
Source: Cancer Medicine - April 23, 2024 Category: Cancer & Oncology Authors: Alexander Popov, Guenter Henze, Grigory Tsaur, Oleg Budanov, Julia Roumiantseva, Mikhail Belevtsev, Tatiana Verzhbitskaya, Liudmila Movchan, Svetlana Lagoyko, Liudmila Zharikova, Yulia Olshanskaya, Tatiana Riger, Alena Valochnik, Natalia Miak Tags: RESEARCH ARTICLE Source Type: research

A Study to Evaluate the Effectiveness and Safety of Prephase Steroid Treatment before Remission Induction Chemotherapy in Patients with Pediatric Acute Lymphoblastic Leukemia Using Common Data Model-Based Real-World Data: A Retrospective Observational Study
(Source: Clinical Epidemiology)
Source: Clinical Epidemiology - April 22, 2024 Category: Epidemiology Tags: Clinical Epidemiology Source Type: research

Enhancing the performance of an InAsSb/InAlSb-based pBn photodetector for early detection of a biomarker of bone marrow cancer: a proposed and simulated approach with extended-midwave response and step-graded barrier design
In this study, we introduce a new extended-mid-wavelength InAsSb-based pBn architecture infrared barrier photodetector with an InAlSb compositional step-graded barrier (SGB), referred to as SGB-pBn-PD, designed specifically to detect a biomarker of bone marrow cancer. Our device outperforms conventional design by replacing the compositional uniform barrier with a step-graded barrier, resulting in improved alignment of the valence band in the barrier and absorber interface, and reduced dark current density via suppression of the Shockley –Read–Hall process. Our simulations show that the dark current density of this dete...
Source: Sensing and Imaging - April 22, 2024 Category: Biomedical Engineering Source Type: research

Impact of the COVID-19 pandemic on utilization and cost for care of pediatric and young adult ALL
Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy and among the most common malignancies in young adults and requires a unique pattern of healthcare utilization including an acute/emer... (Source: BMC Research Notes)
Source: BMC Research Notes - April 22, 2024 Category: Research Authors: Alex Hoover, Dave Watson, Paige Reimche, Lynn Tanner, Laura Gilchrist, Mike Finch, Yoav H Messinger and Lucie M. Turcotte Tags: Research Note Source Type: research

A rare KMT2A::CBL transcript in an acute monoblastic leukemia patient with an unfavorable outcome
CONCLUSIONS: This report provides novel insights into the leukemogenic potential of the KMT2A::CBL rearrangement and the correlation between gene rearrangements and clinical outcomes.PMID:38643442 | PMC:PMC11033236 | DOI:10.1007/s11033-024-09543-0 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - April 21, 2024 Category: Molecular Biology Authors: Jinglei Yu Fengmei Song Mingming Zhang Pingnan Xiao Jingjing Feng Ruimin Hong Yongxian Hu He Huang Guoqing Wei Source Type: research

Cancers, Vol. 16, Pages 1580: T-Cell Engagers & mdash;The Structure and Functional Principle and Application in Hematological Malignancies
Cancers, Vol. 16, Pages 1580: T-Cell Engagers—The Structure and Functional Principle and Application in Hematological Malignancies Cancers doi: 10.3390/cancers16081580 Authors: Paweł Cech Katarzyna Skórka Laura Dziki Krzysztof Giannopoulos Recent advancements in cancer immunotherapy have made directing the cellular immune response onto cancer cells a promising strategy for the treatment of hematological malignancies. The introduction of monoclonal antibody-based (mAbs) targeted therapy has significantly improved the prognosis for hematological patients. Facing the issues of mAb-based therapies, a ...
Source: Cancers - April 20, 2024 Category: Cancer & Oncology Authors: Pawe ł Cech Katarzyna Sk órka Laura Dziki Krzysztof Giannopoulos Tags: Review Source Type: research

Extramedullary relapsed acute lymphoblastic leukemia presenting as asymptomatic acute kidney injury after hematopoietic stem cell transplantation
AbstractAcute kidney injury (AKI) is a common complication in children with hematological malignancies. Although AKI due to infiltration of tumor cells in children is rare, it negatively impacts treatment outcomes and increases the risk of mortality. We introduce a case of a child with acute lymphoblastic leukemia (ALL) who experienced kidney relapse resulting in asymptomatic AKI after remission from treatment, to remind clinicians not to overlook the primary disease in clinical judgment. In cases of unexplained AKI, kidney biopsy should be performed when feasible to get an accurate diagnosis and scientific treatment. In b...
Source: Pediatric Nephrology - April 19, 2024 Category: Urology & Nephrology Source Type: research

High expression of SLC27A2 predicts unfavorable prognosis and promotes inhibitory immune infiltration in acute lymphoblastic leukemia
In conclusion, SLC27A2 plays a vital role in the development of ALL.PMID:38640787 | DOI:10.1016/j.tranon.2024.101952 (Source: Translational Oncology)
Source: Translational Oncology - April 19, 2024 Category: Cancer & Oncology Authors: Lihua Lu Jiazheng Li Yongzhi Zheng Luting Luo Yan Huang Jianda Hu Yanxin Chen Source Type: research