Abstracts of the International Perinatal & amp; Paediatric Forensic Pathology Conference 2021 (IPPFPC 2021), organised by Chapter of Perinatal & amp; Paediatric Pathology, College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):131-135.ABSTRACTNo abstract available.PMID:33903316 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

Abstracts of the International Congress of Pathology and Laboratory Medicine 2021 (ICPaLM 2021) and 18th Annual Scientific Meeting, College of Pathologists: Exploring the Advances and Potential of Disruptive Technologies in Pathology and Laboratory Medicine, organised by College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):127-130.ABSTRACTNo abstract available.PMID:33903315 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

The journey of Malaysian external quality assurance program for general diagnostic histopathology
This article introduces the educational philosophy of this external quality assurance program and the technicalities in running such a national program. Challenges in ensuring the successful running of this program to gain wide acceptance by histopathology laboratories in Malaysia as well as experience in overcoming these challenges are detailed. This article charts the future direction of this external quality assurance program.PMID:33903301 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Authors: E S Ch'ng N H Othman Source Type: research

Abstracts of the International Perinatal & amp; Paediatric Forensic Pathology Conference 2021 (IPPFPC 2021), organised by Chapter of Perinatal & amp; Paediatric Pathology, College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):131-135.ABSTRACTNo abstract available.PMID:33903316 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

Abstracts of the International Congress of Pathology and Laboratory Medicine 2021 (ICPaLM 2021) and 18th Annual Scientific Meeting, College of Pathologists: Exploring the Advances and Potential of Disruptive Technologies in Pathology and Laboratory Medicine, organised by College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):127-130.ABSTRACTNo abstract available.PMID:33903315 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

Abstracts of the International Perinatal & amp; Paediatric Forensic Pathology Conference 2021 (IPPFPC 2021), organised by Chapter of Perinatal & amp; Paediatric Pathology, College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):131-135.ABSTRACTNo abstract available.PMID:33903316 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

Abstracts of the International Congress of Pathology and Laboratory Medicine 2021 (ICPaLM 2021) and 18th Annual Scientific Meeting, College of Pathologists: Exploring the Advances and Potential of Disruptive Technologies in Pathology and Laboratory Medicine, organised by College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):127-130.ABSTRACTNo abstract available.PMID:33903315 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

The journey of Malaysian external quality assurance program for general diagnostic histopathology
This article introduces the educational philosophy of this external quality assurance program and the technicalities in running such a national program. Challenges in ensuring the successful running of this program to gain wide acceptance by histopathology laboratories in Malaysia as well as experience in overcoming these challenges are detailed. This article charts the future direction of this external quality assurance program.PMID:33903301 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Authors: E S Ch'ng N H Othman Source Type: research

Abstracts of the International Perinatal & amp; Paediatric Forensic Pathology Conference 2021 (IPPFPC 2021), organised by Chapter of Perinatal & amp; Paediatric Pathology, College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):131-135.ABSTRACTNo abstract available.PMID:33903316 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

Abstracts of the International Congress of Pathology and Laboratory Medicine 2021 (ICPaLM 2021) and 18th Annual Scientific Meeting, College of Pathologists: Exploring the Advances and Potential of Disruptive Technologies in Pathology and Laboratory Medicine, organised by College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):127-130.ABSTRACTNo abstract available.PMID:33903315 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

The journey of Malaysian external quality assurance program for general diagnostic histopathology
This article introduces the educational philosophy of this external quality assurance program and the technicalities in running such a national program. Challenges in ensuring the successful running of this program to gain wide acceptance by histopathology laboratories in Malaysia as well as experience in overcoming these challenges are detailed. This article charts the future direction of this external quality assurance program.PMID:33903301 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Authors: E S Ch'ng N H Othman Source Type: research

Abstracts of the International Perinatal & amp; Paediatric Forensic Pathology Conference 2021 (IPPFPC 2021), organised by Chapter of Perinatal & amp; Paediatric Pathology, College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):131-135.ABSTRACTNo abstract available.PMID:33903316 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

Abstracts of the International Congress of Pathology and Laboratory Medicine 2021 (ICPaLM 2021) and 18th Annual Scientific Meeting, College of Pathologists: Exploring the Advances and Potential of Disruptive Technologies in Pathology and Laboratory Medicine, organised by College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):127-130.ABSTRACTNo abstract available.PMID:33903315 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

The journey of Malaysian external quality assurance program for general diagnostic histopathology
This article introduces the educational philosophy of this external quality assurance program and the technicalities in running such a national program. Challenges in ensuring the successful running of this program to gain wide acceptance by histopathology laboratories in Malaysia as well as experience in overcoming these challenges are detailed. This article charts the future direction of this external quality assurance program.PMID:33903301 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Authors: E S Ch'ng N H Othman Source Type: research

Abstracts of the International Perinatal & amp; Paediatric Forensic Pathology Conference 2021 (IPPFPC 2021), organised by Chapter of Perinatal & amp; Paediatric Pathology, College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):131-135.ABSTRACTNo abstract available.PMID:33903316 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

Abstracts of the International Congress of Pathology and Laboratory Medicine 2021 (ICPaLM 2021) and 18th Annual Scientific Meeting, College of Pathologists: Exploring the Advances and Potential of Disruptive Technologies in Pathology and Laboratory Medicine, organised by College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):127-130.ABSTRACTNo abstract available.PMID:33903315 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

The journey of Malaysian external quality assurance program for general diagnostic histopathology
This article introduces the educational philosophy of this external quality assurance program and the technicalities in running such a national program. Challenges in ensuring the successful running of this program to gain wide acceptance by histopathology laboratories in Malaysia as well as experience in overcoming these challenges are detailed. This article charts the future direction of this external quality assurance program.PMID:33903301 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Authors: E S Ch'ng N H Othman Source Type: research

Abstracts of the International Perinatal & amp; Paediatric Forensic Pathology Conference 2021 (IPPFPC 2021), organised by Chapter of Perinatal & amp; Paediatric Pathology, College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):131-135.ABSTRACTNo abstract available.PMID:33903316 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

Abstracts of the International Congress of Pathology and Laboratory Medicine 2021 (ICPaLM 2021) and 18th Annual Scientific Meeting, College of Pathologists: Exploring the Advances and Potential of Disruptive Technologies in Pathology and Laboratory Medicine, organised by College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):127-130.ABSTRACTNo abstract available.PMID:33903315 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

The journey of Malaysian external quality assurance program for general diagnostic histopathology
This article introduces the educational philosophy of this external quality assurance program and the technicalities in running such a national program. Challenges in ensuring the successful running of this program to gain wide acceptance by histopathology laboratories in Malaysia as well as experience in overcoming these challenges are detailed. This article charts the future direction of this external quality assurance program.PMID:33903301 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Authors: E S Ch'ng N H Othman Source Type: research

Abstracts of the International Perinatal & amp; Paediatric Forensic Pathology Conference 2021 (IPPFPC 2021), organised by Chapter of Perinatal & amp; Paediatric Pathology, College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):131-135.ABSTRACTNo abstract available.PMID:33903316 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

Abstracts of the International Congress of Pathology and Laboratory Medicine 2021 (ICPaLM 2021) and 18th Annual Scientific Meeting, College of Pathologists: Exploring the Advances and Potential of Disruptive Technologies in Pathology and Laboratory Medicine, organised by College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):127-130.ABSTRACTNo abstract available.PMID:33903315 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

The journey of Malaysian external quality assurance program for general diagnostic histopathology
This article introduces the educational philosophy of this external quality assurance program and the technicalities in running such a national program. Challenges in ensuring the successful running of this program to gain wide acceptance by histopathology laboratories in Malaysia as well as experience in overcoming these challenges are detailed. This article charts the future direction of this external quality assurance program.PMID:33903301 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Authors: E S Ch'ng N H Othman Source Type: research

Abstracts of the International Perinatal & amp; Paediatric Forensic Pathology Conference 2021 (IPPFPC 2021), organised by Chapter of Perinatal & amp; Paediatric Pathology, College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):131-135.ABSTRACTNo abstract available.PMID:33903316 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

Abstracts of the International Congress of Pathology and Laboratory Medicine 2021 (ICPaLM 2021) and 18th Annual Scientific Meeting, College of Pathologists: Exploring the Advances and Potential of Disruptive Technologies in Pathology and Laboratory Medicine, organised by College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):127-130.ABSTRACTNo abstract available.PMID:33903315 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

The journey of Malaysian external quality assurance program for general diagnostic histopathology
This article introduces the educational philosophy of this external quality assurance program and the technicalities in running such a national program. Challenges in ensuring the successful running of this program to gain wide acceptance by histopathology laboratories in Malaysia as well as experience in overcoming these challenges are detailed. This article charts the future direction of this external quality assurance program.PMID:33903301 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Authors: E S Ch'ng N H Othman Source Type: research

Abstracts of the International Perinatal & amp; Paediatric Forensic Pathology Conference 2021 (IPPFPC 2021), organised by Chapter of Perinatal & amp; Paediatric Pathology, College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):131-135.ABSTRACTNo abstract available.PMID:33903316 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

Abstracts of the International Congress of Pathology and Laboratory Medicine 2021 (ICPaLM 2021) and 18th Annual Scientific Meeting, College of Pathologists: Exploring the Advances and Potential of Disruptive Technologies in Pathology and Laboratory Medicine, organised by College of Pathologists, Academy of Medicine of Malaysia
Malays J Pathol. 2021 Apr;43(1):127-130.ABSTRACTNo abstract available.PMID:33903315 (Source: Malaysian Journal of Pathology)
Source: Malaysian Journal of Pathology - April 27, 2021 Category: Pathology Source Type: research

Accuracy of Breast Fine-Needle Aspiration Biopsy Using the International Academy of Cytology Yokohama System in Clinico-Radiologically Indeterminate Lesions: Initial Findings Demonstrating Value in Lesions of Low Suspicion of Malignancy
Conclusion: The study reconfirms the excellent accuracy of breast FNAB using the IAC Yokohama system in diagnosing breast malignancies. Furthermore, BIRADS 4a lesions found to be belonging to the cytological benign category may be excluded from CRB and kept on clinical follow-up.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - April 27, 2021 Category: Cytology Source Type: research

Evidence-based clinical practice guideline: Reconstruction after skin cancer resection
A multi-disciplinary work group involving stakeholders from various backgrounds and societies was convened to develop guidelines for the management of reconstruction after skin cancer resection. The goal was to identify areas of common ground and provide evidence-based recommendations to improve patient care. Given the heterogeneity of reconstructive techniques and clinical scenarios, investigation centered around common elements in the process. In some cases, a distinction was made between treatment options in the office-based setting as opposed to those in the facility setting. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - April 27, 2021 Category: Dermatology Authors: Andrew Chen, John G. Albertini, Jeremy S. Bordeaux, Michael W. Chen, Jonathan L. Cook, Caryn Davidson, Katelyn C. Donnelly, Irfan I. Galaria, Catherine M. Hannan, Jonathan Kantor, Daniel L. Kapp, Naomi Lawrence, Clifford W. Lober, Lauren D. Loeding, Alexa Tags: From the academy Source Type: research

In This Issue [This Week in PNAS]
EVOLUTION Fairydale, Bethulie, in South Africa’s Karoo Basin. End-Permian extinction patterns in South Africa The greatest mass extinction on Earth occurred at the end of the Permian Period, approximately 252 million years ago. However, there are few quantitative investigations of the extinction’s impact on land animals. Pia Viglietti et al.... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - April 27, 2021 Category: Science Tags: In This Issue This Week in PNAS Source Type: research

Adaptive differentiation and rapid evolution of a soil bacterium along a climate gradient [Ecology]
Microbial community responses to environmental change are largely associated with ecological processes; however, the potential for microbes to rapidly evolve and adapt remains relatively unexplored in natural environments. To assess how ecological and evolutionary processes simultaneously alter the genetic diversity of a microbiome, we conducted two concurrent experiments in the... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - April 27, 2021 Category: Science Authors: Alexander B. Chase, Claudia Weihe, Jennifer B. H. Martiny Tags: Ecology Biological Sciences Source Type: research

Improved bounds on entropy production in living systems [Biophysics and Computational Biology]
Living systems maintain or increase local order by working against the second law of thermodynamics. Thermodynamic consistency is restored as they consume free energy, thereby increasing the net entropy of their environment. Recently introduced estimators for the entropy production rate have provided major insights into the efficiency of important cellular... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - April 27, 2021 Category: Science Authors: Dominic J. Skinner, Jorn Dunkel Tags: Biophysics and Computational Biology Physical Sciences Source Type: research

Redox control on the tungsten isotope composition of seawater [Earth, Atmospheric, and Planetary Sciences]
Free oxygen represents an essential basis for the evolution of complex life forms on a habitable Earth. The isotope composition of redox-sensitive trace elements such as tungsten (W) can possibly trace the earliest rise of oceanic oxygen in Earth’s history. However, the impact of redox changes on the W isotope... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - April 27, 2021 Category: Science Authors: Florian Kurzweil, Corey Archer, Martin Wille, Ronny Schoenberg, Carsten Munker, Olaf Dellwig Tags: Earth, Atmospheric, and Planetary Sciences Physical Sciences Source Type: research

Blood-brain barrier opening by intracarotid artery hyperosmolar mannitol induces sterile inflammatory and innate immune responses [Immunology and Inflammation]
Intracarotid arterial hyperosmolar mannitol (ICAHM) blood–brain barrier disruption (BBBD) is effective and safe for delivery of therapeutics for central nervous system malignancies. ICAHM osmotically alters endothelial cells and tight junction integrity to achieve BBBD. However, occurrence of neuroinflammation following hemispheric BBBD by ICAHM remains unknown. Temporal proteomic changes in rat... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - April 27, 2021 Category: Science Authors: Scott R. Burks, Cymon N. Kersch, Jaclyn A. Witko, Michael A. Pagel, Maggie Sundby, Leslie L. Muldoon, Edward A. Neuwelt, Joseph A. Frank Tags: Immunology and Inflammation Biological Sciences Source Type: research

Anaerobic gut fungi are an untapped reservoir of natural products [Microbiology]
Anaerobic fungi (class Neocallimastigomycetes) thrive as low-abundance members of the herbivore digestive tract. The genomes of anaerobic gut fungi are poorly characterized and have not been extensively mined for the biosynthetic enzymes of natural products such as antibiotics. Here, we investigate the potential of anaerobic gut fungi to synthesize natural... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - April 27, 2021 Category: Science Authors: Candice L. Swift, Katherine B. Louie, Benȷamin P. Bowen, Heather M. Olson, Samuel O. Purvine, Asaf Salamov, Stephen J. Mondo, Kevin V. Solomon, Aaron T. Wright, Trent R. Northen, Igor V. Grigoriev, Nancy P. Keller, Michelle A. O’Malley Tags: Microbiology Biological Sciences Source Type: research

High-throughput functional variant screens via in vivo production of single-stranded DNA [Microbiology]
Creating and characterizing individual genetic variants remains limited in scale, compared to the tremendous variation both existing in nature and envisioned by genome engineers. Here we introduce retron library recombineering (RLR), a methodology for high-throughput functional screens that surpasses the scale and specificity of CRISPR-Cas methods. We use the targeted... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - April 27, 2021 Category: Science Authors: Max G. Schubert, Daniel B. Goodman, Timothy M. Wannier, Divjot Kaur, Fahim Farzadfard, Timothy K. Lu, Seth L. Shipman, George M. Church Tags: Microbiology Biological Sciences Source Type: research

Communication consumes 35 times more energy than computation in the human cortex, but both costs are needed to predict synapse number [Biophysics and Computational Biology]
Darwinian evolution tends to produce energy-efficient outcomes. On the other hand, energy limits computation, be it neural and probabilistic or digital and logical. Taking a particular energy-efficient viewpoint, we define neural computation and make use of an energy-constrained computational function. This function can be optimized over a variable that is... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - April 27, 2021 Category: Science Authors: William B Levy, Victoria G. Calvert Tags: Biophysics and Computational Biology, Neuroscience Biological Sciences Source Type: research

Genetic removal of p70 S6K1 corrects coding sequence length-dependent alterations in mRNA translation in fragile X syndrome mice [Neuroscience]
Loss of the fragile X mental retardation protein (FMRP) causes fragile X syndrome (FXS). FMRP is widely thought to repress protein synthesis, but its translational targets and modes of control remain in dispute. We previously showed that genetic removal of p70 S6 kinase 1 (S6K1) corrects altered protein synthesis as... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - April 27, 2021 Category: Science Authors: Sameer Aryal, Francesco Longo, Eric Klann Tags: Neuroscience Biological Sciences Source Type: research

Network medicine framework for identifying drug-repurposing opportunities for COVID-19 [Systems Biology]
The COVID-19 pandemic has highlighted the need to quickly and reliably prioritize clinically approved compounds for their potential effectiveness for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. Here, we deployed algorithms relying on artificial intelligence, network diffusion, and network proximity, tasking each of them to rank 6,340 drugs for... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - April 27, 2021 Category: Science Authors: Deisy Morselli Gysi, Italo do Valle, Marinka Zitnik, Asher Ameli, Xiao Gan, Onur Varol, Susan Dina Ghiassian, J. J. Patten, Robert A. Davey, Joseph Loscalzo, Albert–Laszlo Barabasi Tags: Systems Biology, Coronavirus (COVID-19) Biological Sciences Source Type: research

Interacting regional policies in containing a disease [Economic Sciences]
Regional quarantine policies, in which a portion of a population surrounding infections is locked down, are an important tool to contain disease. However, jurisdictional governments—such as cities, counties, states, and countries—act with minimal coordination across borders. We show that a regional quarantine policy’s effectiveness depends on whether 1) the network... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - April 27, 2021 Category: Science Authors: Arun G. Chandrasekhar, Paul Goldsmith-Pinkham, Matthew O. Jackson, Samuel Thau Tags: Economic Sciences, Coronavirus Related Social Sciences Source Type: research

Correction
The February 2021 issue of the Journal of the American Academy of Child and Adolescent Psychiatry included an editorial entitled “Editorial: Why JAACAP Published an ‘Inconclusive’ Trial: Optimize, Optimize, Optimize Psychostimulant Treatment” (J Am Acad Child Adolesc Psychiatry 60:213-215) by Samuele Cortese and Douglas K. Novins. During the editing process, a paragraph was inadvertently deleted (below), and two sente nces were incorrectly repeated in the article: “Why did JAACAP publish an inconclusive trial? Because, in our view, the lessons that can be learned from this RCT (in particular, ...
Source: Journal of the American Academy of Child and Adolescent Psychiatry - April 27, 2021 Category: Psychiatry Tags: Correction Source Type: research

American College of Rheumatology, American Academy of Dermatology, Rheumatologic Dermatology Society, and American Academy of Ophthalmology 2020 Joint Statement on Hydroxychloroquine Use With Respect to Retinal Toxicity
Four major medical societies involved with hydroxychloroquine (HCQ) therapy concur on the need for common principles and cooperation to minimize the risk of ocular toxicity. At a daily dosage of ≤5 mg/kg/day actual body weight, the risk of retinal toxicity from HCQ is
Source: Arthritis and Rheumatology - April 26, 2021 Category: Rheumatology Authors: James T. Rosenbaum, Karen H. Costenbader, Julianna Desmarais, Ellen M. Ginzler, Nicole Fett, Susan  M. Goodman, James R. O’Dell, Gabriela Schmajuk, Victoria P. Werth, Ronald B. Melles, Michael F. Marmor Tags: SPECIAL ARTICLE Source Type: research

The comparison of two corrective exercise approaches for hyperkyphosis and forward head posture: A quasi-experimental study
J Back Musculoskelet Rehabil. 2021 Apr 20. doi: 10.3233/BMR-200160. Online ahead of print.ABSTRACTBACKGROUND: Hyperkyphosis (HKP) and forward head posture (FHP) occur due to prolonged poor postures and repetitive activities.OBJECTIVE: The present study aimed to compare the effects of the National Academy of Sports Medicine (NASM) and Sahrmann corrective exercises on HKP and FHP correction.METHODS: This quasi-experimental study was conducted on 30 subjects with HKP and FHP, who were randomly assigned to the NASM (n= 15) and Sahrmann groups (n= 15). The ImageJ software and a spinal mouse device were used to measure FHP and H...
Source: Journal of Back and Musculoskeletal Rehabilitation - April 26, 2021 Category: Orthopaedics Authors: Karim Mohammad Jabbar Farzaneh Gandomi Source Type: research

Bridging the Gap: The Influence of Foot and Ankle Pathomechanics in Total Knee Arthroplasty
J Am Acad Orthop Surg. 2021 Apr 26. doi: 10.5435/JAAOS-D-20-00786. Online ahead of print.ABSTRACTAltered spinopelvic mechanics can have dramatic influences on the success of hip arthroplasty as seen with concomitant hip and spine disease. Interestingly, limited focus has been directed toward a similar codependent relationship between concurrent knee and foot deformities. By bridging this interdisciplinary gap, we attempt to explore the current understanding and clinical implications of concomitant knee and foot pathology while reviewing management options for addressing this unique yet ubiquitous patient population. Multip...
Source: The Journal of the American Academy of Orthopaedic Surgeons - April 26, 2021 Category: Orthopaedics Authors: Brandon H Naylor Daniel Seidman Giles R Scuderi Source Type: research

Opioid Claims Prior to Elective Total Joint Arthroplasty and Risk of Prolonged Postoperative Opioid Claims
This study seeks to analyze recent trends in opioid claims after elective total joint arthroplasty and quantify the effect of preoperative opioid use on risk of prolonged postoperative claim rates.METHODS: A retrospective cohort study was conducted using the PearlDiver database to track annual trends in opioid claims after elective total hip arthroplasty (THA), total knee arthroplasty (TKA), and total shoulder arthroplasty (TSA). Trend analysis of opioid claim rates was done with the Cochran-Armitage test. Rates of postoperative opioid claims were compared between opioid-naïve patients versus patients with opioid clai...
Source: The Journal of the American Academy of Orthopaedic Surgeons - April 26, 2021 Category: Orthopaedics Authors: Bailey J Ross Victor J Wu Alfred A Mansour Olivia C Lee William F Sherman Source Type: research

Structures Endangered During Minimally Invasive Plate Osteosynthesis of the Upper Extremity
We describe the critical anatomical structures in these pathways and tips for injury avoidance when operating on the clavicle, scapula, humerus, and wrist.PMID:33902084 | DOI:10.5435/JAAOS-D-20-00799 (Source: The Journal of the American Academy of Orthopaedic Surgeons)
Source: The Journal of the American Academy of Orthopaedic Surgeons - April 26, 2021 Category: Orthopaedics Authors: Brian W Hill Claire N Thomas Lisa K Schroder Peter A Cole Source Type: research

The comparison of two corrective exercise approaches for hyperkyphosis and forward head posture: A quasi-experimental study
J Back Musculoskelet Rehabil. 2021 Apr 20. doi: 10.3233/BMR-200160. Online ahead of print.ABSTRACTBACKGROUND: Hyperkyphosis (HKP) and forward head posture (FHP) occur due to prolonged poor postures and repetitive activities.OBJECTIVE: The present study aimed to compare the effects of the National Academy of Sports Medicine (NASM) and Sahrmann corrective exercises on HKP and FHP correction.METHODS: This quasi-experimental study was conducted on 30 subjects with HKP and FHP, who were randomly assigned to the NASM (n= 15) and Sahrmann groups (n= 15). The ImageJ software and a spinal mouse device were used to measure FHP and H...
Source: Journal of Back and Musculoskeletal Rehabilitation - April 26, 2021 Category: Orthopaedics Authors: Karim Mohammad Jabbar Farzaneh Gandomi Source Type: research