Evaluation and Management of Difficult-to-Treat and Severe Asthma: An Expert Opinion From the Korean Academy of Asthma, Allergy and Clinical Immunology, the Working Group on Severe Asthma.
Authors: Kim BK, Park SY, Ban GY, Kim MA, Lee JH, An J, Shim JS, Lee Y, Won HK, Lee HY, Sohn KH, Kang SY, Park SY, Lee H, Kim MH, Kwon JW, Yoon SY, Lee JH, Rhee CK, Moon JY, Lee T, Kim SR, Park JS, Kim SH, Park HW, Jeong JW, Kim SH, Koh YI, Oh YM, Jang AS, Yoo KH, Cho YS, Korean Academy of Asthma, Allergy, and Clinical Immunology (KAACI), the Working Group on Severe Asthma Abstract Severe asthma (SA) presents in about 3%-5% of adult asthmatics and is responsible for over 60% of asthma-related medical expenses, posing a heavy socioeconomic burden. However, to date, a precise definition of or clear diagnostic criteri...
Source: Allergy, Asthma and Immunology Research - September 18, 2020 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Extreme Wildfires —A Growing Population Health and Planetary Problem
This Viewpoint uses findings from a June 2019 National Academies of Sciences, Engineering, and Medicine (NASEM) workshop report and subsequent data to summarize known environmental and health effects of extreme wildfires, emphasizing their differential adverse effects on low-income, non –English-speaking, and other vulnerable communities. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - September 18, 2020 Category: General Medicine Source Type: research

Six Decades of Scientific Pan-Americanism. An Interview with Jorge E Allende.
Authors: Allende ML Abstract Jorge E. Allende is a biochemist trained in the United States who has been a Professor at the University of Chile since 1961. He has served in many leadership positions in both Chilean and international scientific organizations and academic institutions. He led the International Cell Research Organization, the Latin American Network of Biological Sciences and obtained the Chilean National Science Prize. He belongs to the Chilean Academy of Sciences and is a foreign member of the U. S. National Academy of Sciences and also of the U.S. National Academy of Medicine. During his career, besi...
Source: International Journal of Developmental Biology - September 18, 2020 Category: Biology Tags: Int J Dev Biol Source Type: research

Building the embryo of developmental biology in Uruguay.
Authors: Zolessi FR, Berois N, Brauer MM, Castillo E Abstract In Uruguay, a country with a small population, and hence a small scientific community, there were no classical embryologists as such in the past. From the decade of 1950, however, a cumulus of favorable conditions gave rise to highly active and modern research groups in the fields of cytology and physiology, that eventually contributed to developmental biology. The advent of a long dictatorship between de 1970's and 1980's caused two things: a strong lag in local research and the migration of young investigators who learned abroad new disciplines and tec...
Source: International Journal of Developmental Biology - September 18, 2020 Category: Biology Tags: Int J Dev Biol Source Type: research

Acute Kidney Injury and Risk of CKD and Hypertension after Pediatric Cardiac Surgery.
vestigators Abstract BACKGROUND AND OBJECTIVES: The association of AKI after pediatric cardiac surgery with long-term CKD and hypertension development is unclear. The study objectives were to determine whether AKI after pediatric cardiac surgery is associated with incident CKD and hypertension. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This was a prospective cohort study of children of 1 month to 18 years old who were undergoing cardiac surgery at two tertiary care centers (Canada, United States). Participants were recruited before cardiac surgery and were followed during hospitalization and at 3, 12...
Source: Clinical Journal of the American Society of Nephrology : CJASN - September 18, 2020 Category: Urology & Nephrology Authors: Zappitelli M, Parikh CR, Kaufman JS, Go AS, Kimmel PL, Hsu CY, Coca SG, Chinchilli VM, Greenberg JH, Moxey-Mims MM, Ikizler TA, Cockovski V, Dyer AM, Devarajan P, ASsessment, Serial Evaluation, and Subsequent Sequelae in Acute Kidney Injury (ASSESS-AKI) I Tags: Clin J Am Soc Nephrol Source Type: research

[Acceptance of assistive robots in the field of nursing and healthcare : Representative data show a clear picture for Germany].
This article focuses on the extent to which robots in nursing are accepted by the adult population in Germany today, as well as the extent to which gender, age, and experience (professional and private) influence this level of acceptance. The analysis carried out for this purpose was based on three representative surveys conducted among a total of over 7000 respondents. Of these surveys two were conducted in the second half of 2017 on behalf of the German Academy of Science and Engineering (acatech) and the life insurance company ERGO, while the third was commissioned by the German Council of Economic Experts (SVRV) i...
Source: Zeitschrift fur Gerontologie und Geriatrie - September 18, 2020 Category: Geriatrics Authors: Rebitschek FG, Wagner GG Tags: Z Gerontol Geriatr Source Type: research

Authors ’ Response:
Discussion of novel personalized nutrition technologies is necessary to improve understanding of how these tools can most effectively be used by registered dietitian nutritionists (RDNs). (Source: Journal of the American Dietetic Association)
Source: Journal of the American Dietetic Association - September 18, 2020 Category: Nutrition Authors: Mary Rozga Tags: Practice Applications Source Type: research

Dermatologist Online Ratings for Botulinum Toxin Injections Are Nuanced and May be Misleading
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 18, 2020 Category: Dermatology Authors: Christina Avila, Llana Pootrakul, Desmond Shipp, Susan Massick, Benjamin Kaffenberger Source Type: research

Recognition of Atopic Keratoconjunctivitis During Treatment with Dupilumab for Atopic Dermatitis
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 18, 2020 Category: Dermatology Authors: Justine Cheng, Lai Jiang, Nicole C. Morrow, Armin Avdic, Janet A. Fairley, Jennifer J. Ling, Mark A. Greiner Source Type: research

Intralesional Bleomycin Injection for Localized Verrucous Venous malformations
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 18, 2020 Category: Dermatology Authors: Shih-Jen Chang, Lili Qian, Han-Yu Lee, Hui Chen, Gang Ma, Yajing Qiu, Xiaoxi Lin Source Type: research

Soft-tissue Sarcoma of the Hand: Patient Characteristics, Treatment, and Oncologic Outcomes.
CONCLUSION: Hand STSs are aggressive tumors with a high metastatic potential. Even with adequate oncologic treatment, long-term clinical follow-up (10 years) in these tumors is advised. The treating surgical oncologist should not be deceived by their smaller size. PMID: 32932303 [PubMed - as supplied by publisher] (Source: The Journal of the American Academy of Orthopaedic Surgeons)
Source: The Journal of the American Academy of Orthopaedic Surgeons - September 17, 2020 Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research

Career Readiness in the Dietetics Curriculum
Publication date: Available online 17 September 2020Source: Journal of the Academy of Nutrition and DieteticsAuthor(s): Nicholas A. Koemel, Kiyan Shafieizadeh, Brecca R. Farr (Source: Journal of the Academy of Nutrition and Dietetics)
Source: Journal of the Academy of Nutrition and Dietetics - September 17, 2020 Category: Nutrition Source Type: research

Growth of Private Equity in Dermatology Through Acquisitions and New Clinic Formation, 2018-2019
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 17, 2020 Category: Dermatology Authors: Kira Seiger, Elizabeth Tkachenko, Arash Mostaghimi Source Type: research

The scalp is a high-risk site for cutaneous squamous cell carcinoma metastasis
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 17, 2020 Category: Dermatology Authors: Julia Mo, Christopher J. Miller, Giorgios Karakousis, Luke Keele, Justine Cohen, Robert S. Krouse Source Type: research

Twice-weekly topical calcipotriene / betamethasone dipropionate foam as proactive management of plaque psoriasis increases time in remission and is well tolerated over 52 weeks (PSO-LONG trial)
Capsule summary Long-term disease control is challenging for patients with psoriasis. Current topical treatment follows a reactive approach to disease relapse.Long-term proactive management with calcipotriene/betamethasone dipropionate foam twice-weekly was more efficacious versus vehicle foam for prolonging time to first relapse, increasing time in remission and reducing number of relapses. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 17, 2020 Category: Dermatology Authors: Mark Lebwohl, Leon Kircik, Jean-Philippe Lacour, Monika Liljedahl, Charles Lynde, Marie Holst M ørch, Kim A. Papp, Jean-Luc Perrot, Linda Stein Gold, Amrit Takhar, Diamant Thaçi, Richard B. Warren, Andreas Wollenberg Source Type: research

Subungual Glomus Tumors: Underrecognized Clinical Findings in Neurofibromatosis 1
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 17, 2020 Category: Dermatology Authors: Shari R. Lipner, Richard K. Scher Source Type: research

Brain Functional Connectivity Correlates of Subclinical Obsessive-Compulsive Symptoms in Healthy Children
The commonly observed Subclinical Obsessive-Compulsive (OC) symptoms in healthy children may predispose to Obsessive-Compulsive Disorder (OCD). Therefore, investigating the underlying neurobiology may be relevant to identify alterations in specific brain circuits potentially accounting for clinical heterogeneity in OCD without the confounding effects of clinical samples. Herein, we analyzed the brain correlates of different OC symptoms in a large group of healthy children using functional connectivity measures. (Source: Journal of the American Academy of Child and Adolescent Psychiatry)
Source: Journal of the American Academy of Child and Adolescent Psychiatry - September 17, 2020 Category: Psychiatry Authors: Maria Su ñol, Cristina Saiz-Masvidal, Oren Contreras-Rodríguez, Dídac Macià, Gerard Martínez-Vilavella, Ignacio Martínez-Zalacaín, José Manuel Menchón, Jesús Pujol, Jordi Sunyer, Carles Soriano-Mas Tags: New Research Source Type: research

The p Factor Consistently Predicts Long-Term Psychiatric and Functional Outcomes in Anxiety-Disordered Youth
Pediatric anxiety disorders can have a chronic course and are considered gateway disorders to adult psychopathology, but no consistent predictors of long-term outcome have been identified. A single latent symptom dimension that reflects features shared by all mental health disorders, the p factor, is thought to reflect mechanisms that cut across mental disorders. Whether p predicts outcome in youth with psychiatric disorders has not been examined. We tested whether the p factor predicted long-term psychiatric and functional outcomes in a large naturalistically followed-up cohort of anxiety-disordered youth. (Source: Journa...
Source: Journal of the American Academy of Child and Adolescent Psychiatry - September 17, 2020 Category: Psychiatry Authors: Matti Cervin, Lesley A. Norris, Golda Ginsburg, Elizabeth A. Gosch, Scott N. Compton, John Piacentini, Anne Marie Albano, Dara Sakolsky, Boris Birmaher, Courtney Keeton, Eric A. Storch, Philip C. Kendall Tags: New Research Source Type: research

Occupational Dermatoses Among Frontline Healthcare Workers During the COVID-19 Pandemic: A Cross-Sectional Survey
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 17, 2020 Category: Dermatology Authors: Nicole Trepanowski, Allison R. Larson, Rachel Evers-Meltzer Source Type: research

Music Reduces Pain and Anxiety Associated with Local Anesthesia for Dermatologic Procedures: A Randomized Controlled Trial
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 17, 2020 Category: Dermatology Authors: Eric P. Sorensen, Hongjie Gu, Mary Tabacchi, M. Laurin Council Source Type: research

Melanoma In-Situ and Invasive Melanoma of the Vulva: an Analysis of the National Cancer Database
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 17, 2020 Category: Dermatology Authors: Sara Behbahani, Stefano Malerba, Christopher J. Warren, Miriam K. Pomeranz, Faramarz H. Samie Source Type: research

Symptom burden of atopic dermatitis in early childhood assessed from daily monitoring of symptoms and topical steroid usage
Capsule summary Traditionally, clinicians have used SCORAD to assess the severity of atopic dermatitis. However, this cross-sectional instrument fails to capture fluctuations in AD, duration, chronicity and treatment. Our study contributes in a new way to the understanding of AD burden in children and may have a clinical utility for personalized prognosis. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 17, 2020 Category: Dermatology Authors: Iben Frier Ruge, Sunna Thorsteinsd óttir, Sarah Nørgaard, Bo L. Chawes, Klaus Bønnelykke, Jakob Stokholm, Hans Bisgaard Source Type: research

Pain management in hidradenitis suppurativa and a proposed treatment algorithm
This article proposes a dermatology-oriented algorithm for hidradenitis suppurativa pain managem ent that is based on the pain’s chronicity and character (classified as nociceptive or neuropathic) (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 17, 2020 Category: Dermatology Authors: Kevin T. Savage, Vinita Singh, Zarine S. Patel, Christine A. Yannuzzi, Anne Marie McKenzie-Brown, Michelle A. Lowes, Lauren A.V. Orenstein Source Type: research

Response to Commentary on “Role of Phototherapy in the Era of Biologics”
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 17, 2020 Category: Dermatology Authors: Angeli Eloise Torres, Alexis B. Lyons, Iltefat H. Hamzavi, Henry W. Lim Source Type: research

Commentary on ‘‘Role of Phototherapy in the Era of Biologics’’
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 17, 2020 Category: Dermatology Authors: Aysenur Botsali Source Type: research

Neurofibromatosis Type 1 and Subungual Glomus Tumors: A Noteworthy Association
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 17, 2020 Category: Dermatology Authors: Robert A. Schwartz, Britney N. Wilson, Ann M. John, Marc Zachary Handler Source Type: research

Female pattern hair loss in men: a distinct clinical variant of androgenetic alopecia
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 17, 2020 Category: Dermatology Authors: Karolina L. Kerkemeyer, Lara Trindade de Carvalho, Rebekka Jerjen, Jared John, Rodney D. Sinclair, Joel Pinczewski, Bevin Bhoyrul Source Type: research

A national webinar for dermatology applicants during the COVID-19 pandemic
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 17, 2020 Category: Dermatology Authors: Caitlin M. Brumfiel, Itisha S. Jefferson, Albert G. Wu, Jennifer L. Strunck, Surya Veerabagu, Krysta Lin, Robert T. Brodell, Ilana S. Rosman Source Type: research

Preschool Age Predictors of Adolescent Borderline Personality Symptoms
Developmental models of Borderline Personality Disorder (BPD) have highlighted the interplay of psychological variables (i.e., impulsivity and emotional reactivity) with social risk factors including invalidating parenting and childhood trauma. Prospective longitudinal studies have demonstrated the association of BPD with social, familial and psychological antecedents. However, to date, few of these studies have studied the interaction of multiple risk domains and their potential manifestations in the preschool period. (Source: Journal of the American Academy of Child and Adolescent Psychiatry)
Source: Journal of the American Academy of Child and Adolescent Psychiatry - September 17, 2020 Category: Psychiatry Authors: Ben Geselowitz, Diana J. Whalen, Rebecca Tillman, Deanna M. Barch, Joan L. Luby, Alecia Vogel Tags: New Research Source Type: research

Preoperative Opioid Use Increases the Cost of Care in Total Joint Arthroplasty.
Authors: Bell KL, Detweiler M, Yayac M, Penna S, Chen AF Abstract INTRODUCTION: Predictors of financial costs related to total joint arthroplasty (TJA) have become increasingly important becuase payment methods have shifted from fee for service to bundled payments. The purpose of this study was to assess the relationship between preoperative opioid use and cost of care in primary TJA. METHODS: A retrospective study was conducted in Medicare patients who underwent elective unilateral primary total knee or hip arthroplasty between 2015 and 2018. Preoperative opioid usage, comorbidities, length of stay, and demogr...
Source: The Journal of the American Academy of Orthopaedic Surgeons - September 16, 2020 Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research

Defining Outpatient Hip and Knee Arthroplasties: A Systematic Review.
DISCUSSION: We propose "DASH" (Discharge from ASC to Home) as a new term to define arthroplasties done in an outpatient setting with the patient discharged home the same day. PMID: 32925385 [PubMed - as supplied by publisher] (Source: The Journal of the American Academy of Orthopaedic Surgeons)
Source: The Journal of the American Academy of Orthopaedic Surgeons - September 16, 2020 Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research

Does Surgeon Subspecialty Training Affect Outcomes in the Treatment of Displaced Supracondylar Humerus Fractures in Children?
The objective of this study was to examine patient outcomes and treatment variables for these injuries based on the surgeon subspecialty training. METHODS: A retrospective study of children who had undergone primary closed reduction and percutaneous fixation for displaced supracondylar humerus fractures was done from January 2012 through May 2019. The following four groups with differing orthopaedic subspecialty training were evaluated: (1) pediatric fellowship trained (2) trauma fellowship trained, (3) sports medicine fellowship trained, and (4) all others. Outcomes examined included time to surgery, surgical time, fl...
Source: The Journal of the American Academy of Orthopaedic Surgeons - September 16, 2020 Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research

Resident Selection in the Wake of United States Medical Licensing Examination Step 1 Transition to Pass/Fail Scoring.
DISCUSSION: As Step 2 CK is expected to become more important in the residency application process, current applicant stress on Step 1 scores may simply move to Step 2 CK scores. Performance on subinternships will remain a critical aspect of residency application, as it was viewed as the most important resident selection factor and has grown in importance compared with a previous report. PMID: 32925383 [PubMed - as supplied by publisher] (Source: The Journal of the American Academy of Orthopaedic Surgeons)
Source: The Journal of the American Academy of Orthopaedic Surgeons - September 16, 2020 Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research

Patient-reported Outcomes Associated With Preoperative Opioid Use in Revision Total Hip Arthroplasty: A Propensity Score-Matched Cohort Study.
Authors: Smith E, Klemt C, Sabeh K, Tirumala V, Kwon YM Abstract BACKGROUND: Opioid use is a public health crisis in the United States and an area of increased focus within the arthroplasty literature. The aim of this study was to investigate the effect of preoperative opioid use on patient-reported outcome measures (PROMs) before and after revision total hip arthroplasty (THA). METHODS: A total of 381 consecutive revision THA patients with both preoperative and postoperative PROMs were identified. Because of differences in baseline characteristics, 104 opioid users were matched to 208 nonusers using nearest-ne...
Source: The Journal of the American Academy of Orthopaedic Surgeons - September 16, 2020 Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research

Dual-Mobility Articulations in Femoral Neck Fractures: A Systematic Review of the Literature and Meta-analysis of the Outcomes.
CONCLUSIONS: Our study revealed overall lower risk of dislocation using DMC compared with both CTHA and HA. There were also lower revision and revision surgery rates when DMC were used compared with HA. Further studies are required to elucidate cost-effectiveness and long-term outcomes of DMC in these scenarios. LEVEL OF EVIDENCE: Level III-meta-analysis. PMID: 32925381 [PubMed - as supplied by publisher] (Source: The Journal of the American Academy of Orthopaedic Surgeons)
Source: The Journal of the American Academy of Orthopaedic Surgeons - September 16, 2020 Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research

Shared Decision-making in Orthopaedic Surgery.
This article is intended to give the practicing orthopaedic surgeon an understanding of the concept of SDM and how it can improve physician-patient communication. We will explore the key elements of SDM, attendant benefits, indications, and barriers to implementation and propose steps to begin the incorporation of SDM into practice. PMID: 32925380 [PubMed - as supplied by publisher] (Source: The Journal of the American Academy of Orthopaedic Surgeons)
Source: The Journal of the American Academy of Orthopaedic Surgeons - September 16, 2020 Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research

Patient Opioid Requirements Are Often Far Less Than Their Discharge Prescription After Orthopaedic Surgery: the Results of a Prospective Multicenter Survey.
Authors: Wyles CC, Thiels CA, Hevesi M, Ubl DS, Gazelka HM, Turner NS, Trousdale RT, Pagnano MW, Mabry TM, Habermann EB Abstract INTRODUCTION: Evidence-based, procedure-specific guidelines for opioid prescribing after orthopaedic surgery are urgently needed to standardize care and minimize excess opioids. METHODS: We developed a prospective, multicenter survey study conducted from March 2017 to January 2018 including 7 common elective orthopaedic surgical procedures (total knee arthroplasty, total hip arthroplasty, lumbar fusion, lumbar laminectomy, rotator cuff repair, arthroscopic meniscectomy, and carpal tun...
Source: The Journal of the American Academy of Orthopaedic Surgeons - September 16, 2020 Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research

Transition from a Standard to a Hybrid On-Site and Remote Anatomic Pathology Training Model During the COVID-19 Pandemic.
CONCLUSIONS: Hybrid on-site and remote training can maximize anatomic pathology learning opportunities while maintaining the safety of trainees, hospital personnel, and the community. PMID: 32937659 [PubMed - as supplied by publisher] (Source: Archives of Pathology and Laboratory Medicine)
Source: Archives of Pathology and Laboratory Medicine - September 16, 2020 Category: Laboratory Medicine Authors: Chin KE, Kwon D, Gan Q, Ramalingam PX, Wistuba II, Prieto VG, Aung PP Tags: Arch Pathol Lab Med Source Type: research

Brain Morphology Associated With Obsessive-Compulsive Symptoms In 2,551 Children From the General Population
Obsessive-compulsive symptoms (OCS) are common in the general population, but it is unclear whether subclinical OCS symptoms and obsessive-compulsive disorder (OCD) are part of a neuroanatomical continuum. The goal of this study was to investigate the relationship between OCS and subcortical and cortical morphology in a population-based sample of children. (Source: Journal of the American Academy of Child and Adolescent Psychiatry)
Source: Journal of the American Academy of Child and Adolescent Psychiatry - September 16, 2020 Category: Psychiatry Authors: Cees J. Weeland, Tonya White, Chris Vriend, Ryan L. Muetzel, Julia Starreveld, Manon H.J. Hillegers, Henning Tiemeier, Odile A. van den Heuvel Tags: New Research Source Type: research

Elements of the New Conversation
In the editorial comment1 on Greenhill et al. ’s report of new MTA data on growth effects of stimulant medication for ADHD2, Dr. Charach calls for a new conversation on stimulant use and makes several important points that we would like to amplify. (Source: Journal of the American Academy of Child and Adolescent Psychiatry)
Source: Journal of the American Academy of Child and Adolescent Psychiatry - September 16, 2020 Category: Psychiatry Authors: L. Eugene Arnold, Jeanette Johnstone, Barbara Gracious, Andrew J. Hughes, Irene Hatsu, Brenda Leung, Margaret H. Sibley Tags: Letter to the Editor Source Type: research

Insidious Onset of Serotonin Syndrome in a 6-Year-Old Boy
Serotonin syndrome, characterized by autonomic, neuromuscular, and mental status changes, is an uncommon but well-established risk of psychotropic medications. The presentation can be highly variable, especially when triggered by agents with effects on additional neurotransmitters.1 Presence of a nonspecific prodrome has been reported but poorly characterized and can lead to misattribution of symptoms.2 Here we describe a case of serotonin syndrome with insidious onset in a boy treated with multiple medications for behavioral dysregulation. (Source: Journal of the American Academy of Child and Adolescent Psychiatry)
Source: Journal of the American Academy of Child and Adolescent Psychiatry - September 16, 2020 Category: Psychiatry Authors: Lisa Hutchison, Meredith Clark, Scott Shaffer Tags: Letter to the Editor Source Type: research

American Neurotology Society, American Otological Society, and American Academy of Otolaryngology – Head and Neck Foundation Guide to Enhance Otologic and Neurotologic Care During the COVID-19 Pandemic
This combined American Neurotology Society, American Otological Society, and American Academy of Otolaryngology – Head and Neck Surgery Foundation document aims to provide guidance during the coronavirus disease of 2019 (COVID-19) on 1) “priority” of care for otologic and neurotologic patients in the office and operating room, and 2) optimal utilization of personal protective equipment. Given the paucity of evidence to inform otologic and neurotologic best practices during COVID-19, the recommendations herein are based on relevant peer-reviewed articles, the Centers for Disease Control and Prevention COVI...
Source: Otology and Neurotology - September 15, 2020 Category: ENT & OMF Tags: SPECIAL FEATURES Source Type: research

Social Isolation and Loneliness in Older Adults: Review and Commentary of a National Academies Report.
Authors: Donovan NJ, Blazer D Abstract The authors of this review both served on the National Academy of Science, Engineering, and Medicine Committee that produced the report, "Social Isolation and Loneliness in Older Adults: Opportunities for the Health Care System." In 2018, the AARP Foundation commissioned the National Academies to establish a committee to research and develop a report on social isolation and loneliness in persons 50 years of age and older. Emphasis was placed upon the role of the healthcare system in addressing this fundamental public health problem. The committee released the report ...
Source: The American Journal of Geriatric Psychiatry - September 15, 2020 Category: Psychiatry Tags: Am J Geriatr Psychiatry Source Type: research

Sunscreens in the United States: Current Status and Future Outlook.
Authors: Glaser KS, Tomecki KJ Abstract Incidence rates of nonmelanoma skin cancer and melanoma have been on the rise in the USA for the past 25 years. UV radiation (UVR) exposure remains the most preventable environmental risk factor for these cancers. Aside from sun avoidance, sunscreens continue to provide the best alternative protection. UVR directly damages DNA and causes indirect cellular damage through the creation of reactive oxygen species, the sum of which leads to cutaneous immunosuppression and a tumorigenic milieu. The current generation of sunscreens protect from UVR through two main mechanisms: ...
Source: Advances in Experimental Medicine and Biology - September 15, 2020 Category: Research Tags: Adv Exp Med Biol Source Type: research

TEMPORARY REMOVAL: Sociocultural attitudes and barriers to care in minority dermatology patients: A single-center comparative survey study
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - September 15, 2020 Category: Dermatology Authors: Kaushik P. Venkatesh, Kamaria Nelson, Adam Friedman Source Type: research

Prognostic analysis of recurrence in children and adolescents with differentiated thyroid cancer.
This study retrospectively analyzed children and adolescents with DTC who were treated between January 1999 and December 2014 at the Cancer Hospital, Chinese Academy of Medical Sciences. Clinicopathological results and outcomes were collected. A log-rank test of Kaplan-Meier curves and the Cox regression model were used to determine the factors associated with recurrence. RESULTS: Data of 150 patients were collected in this study. During the follow-up, there was only one disease-related death. The recurrence rates at 3, 5, and 10 years were 13.6%, 18.7%, and 28.6%, respectively. There was a significant difference in t...
Source: Chinese Medical Journal - September 15, 2020 Category: General Medicine Authors: Wang X, Wang XL Tags: Chin Med J (Engl) Source Type: research

Anaphylaxis: Recognition and Management.
Abstract Anaphylaxis is a life-threatening systemic reaction, normally occurring within one to two hours of exposure to an allergen. The incidence of anaphylaxis in the United States is 2.1 per 1,000 person-years. Most anaphylactic reactions occur outside the hospital setting. Urticaria, difficulty breathing, and mucosal swelling are the most common symptoms of anaphylaxis. The most common triggers are medications, stinging insect venoms, and foods; however, unidentified triggers occur in up to one-fifth of cases. Coexisting asthma, mast cell disorders, older age, underlying cardiovascular disease, peanut and tree...
Source: American Family Physician - September 15, 2020 Category: Primary Care Authors: Pflipsen MC, Vega Colon KM Tags: Am Fam Physician Source Type: research

Appropriate Use of Opioids for Chronic Pain.
PMID: 32931211 [PubMed - in process] (Source: American Family Physician)
Source: American Family Physician - September 15, 2020 Category: Primary Care Authors: Roth AR, Lazris A, Haskell H, James J Tags: Am Fam Physician Source Type: research

Basal Cell and Cutaneous Squamous Cell Carcinomas: Diagnosis and Treatment.
Abstract Keratinocyte carcinoma, traditionally referred to as nonmelanoma skin cancer, includes basal cell and cutaneous squamous cell carcinoma and is the most common skin cancer malignancy found in humans. The U.S. Preventive Services Task Force recommends counseling about minimizing exposure to ultraviolet radiation for people aged six months to 24 years with fair skin types to decrease their risk of skin cancer. Routine screening for skin cancer is controversial. The U.S. Preventive Services Task Force concludes that current evidence is insufficient to assess the balance of benefits and harms of a routine whol...
Source: American Family Physician - September 15, 2020 Category: Primary Care Authors: Firnhaber JM Tags: Am Fam Physician Source Type: research

Persistent Asymptomatic Rash.
PMID: 32931213 [PubMed - in process] (Source: American Family Physician)
Source: American Family Physician - September 15, 2020 Category: Primary Care Authors: Lammlein KP, Sylvester JE Tags: Am Fam Physician Source Type: research