Proteome reallocation from amino acid biosynthesis to ribosomes enables yeast to grow faster in rich media [Systems Biology]
Several recent studies have shown that the concept of proteome constraint, i.e., the need for the cell to balance allocation of its proteome between different cellular processes, is essential for ensuring proper cell function. However, there have been no attempts to elucidate how cells’ maximum capacity to grow depends on... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - September 1, 2020 Category: Science Authors: Johan Bȷorkeroth, Kate Campbell, Carl Malina, Rosemary Yu, Francesca Di Bartolomeo, Jens Nielsen Tags: Biological Sciences Source Type: research

Correction for Latoscha et al., c-di-AMP hydrolysis by the phosphodiesterase AtaC promotes differentiation of multicellular bacteria [Correction]
MICROBIOLOGY Correction for “c-di-AMP hydrolysis by the phosphodiesterase AtaC promotes differentiation of multicellular bacteria,” by Andreas Latoscha, David Jan Drexler, Mahmoud M. Al-Bassam, Adrian M. Bandera, Volkhard Kaever, Kim C. Findlay, Gregor Witte, and Natalia Tschowri, which was first published March 18, 2020; 10.1073/pnas.1917080117 (Proc. Natl. Acad. Sci. U.S.A. 117,... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - September 1, 2020 Category: Science Tags: Corrections Source Type: research

Correction for Lim et al., Inhibition of DUX4 expression with antisense LNA gapmers as a therapy for facioscapulohumeral muscular dystrophy [Correction]
MEDICAL SCIENCES Correction for “Inhibition of DUX4 expression with antisense LNA gapmers as a therapy for facioscapulohumeral muscular dystrophy,” by Kenji Rowel Q. Lim, Rika Maruyama, Yusuke Echigoya, Quynh Nguyen, Aiping Zhang, Hunain Khawaja, Sreetama Sen Chandra, Takako Jones, Peter Jones, Yi-Wen Chen, and Toshifumi Yokota, which was first published... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - September 1, 2020 Category: Science Tags: Corrections Source Type: research

Correction for Greenway et al., Convergent evolution of conserved mitochondrial pathways underlies repeated adaptation to extreme environments [Correction]
EVOLUTION Correction for “Convergent evolution of conserved mitochondrial pathways underlies repeated adaptation to extreme environments,” by Ryan Greenway, Nick Barts, Chathurika Henpita, Anthony P. Brown, Lenin Arias Rodriguez, Carlos M. Rodríguez Peña, Sabine Arndt, Gigi Y. Lau, Michael P. Murphy, Lei Wu, Dingbo Lin, Michael Tobler, Joanna L. Kelley, and... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - September 1, 2020 Category: Science Tags: Corrections Source Type: research

Consensus Guidelines for Pediatric Intensive Care Units in India, 2020.
Abstract BACKGROUND: Consensus Guidelines for Pediatric Intensive Care Units (PICUs) were published in Indian Pediatrics in 2002. OBJECTIVE: The current document represents a recent update in the Indian context, regarding unit design, equipment, organization, staffing as well as admission and discharge criteria for different levels of Pediatric Intensive Care and teaching units with PICU training programs, as well as nonteaching units. PROCESS: The Pediatric Intensive Care College Council (PICC), an academic wing of the Indian Academy of Pediatrics (IAP) Intensive Care Chapter took the initiative to upda...
Source: Indian Pediatrics - August 29, 2020 Category: Pediatrics Authors: Khilnani P, Ramachandran B, Shaikh F, Sharma R, Sachdev A, Deopujari S, Bansal A, Nakate D, Ghorpade S, For Indian Academy Of Pediatrics College Council Of Pediatric Intensive Care Chapter Tags: Indian Pediatr Source Type: research

Socioeconomic Status Is Associated With the Risk of Girdlestone Resection Arthroplasty After Periprosthetic Infection of the Hip.
Authors: Kirchner GJ, Lieber AM, Kim RY, Kerbel YE, Moretti VM, Nikkel LE Abstract INTRODUCTION: Girdlestone resection arthroplasty (GRA) is a radical but sometimes necessary treatment of periprosthetic joint infection (PJI) of the hip. The purpose of this of this study was to identify the independent risk factors for GRA after PJI of the hip. METHODS: This is a retrospective, cross-sectional analysis of the National (Nationwide) Inpatient Sample from 2010 to 2014. The International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) was used to identify 27,404 patients with PJI of the hi...
Source: The Journal of the American Academy of Orthopaedic Surgeons - August 28, 2020 Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research

Letter to the Editor: Venous Thromboembolism Prophylaxis After Pelvic and Acetabular Fractures: A Survey of Orthopaedic Surgeons' Current Practices.
Authors: Liang ZC, OʼNeill G, Murphy D, Hui JHP PMID: 32852331 [PubMed - as supplied by publisher] (Source: The Journal of the American Academy of Orthopaedic Surgeons)
Source: The Journal of the American Academy of Orthopaedic Surgeons - August 28, 2020 Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research

Reply to Letter to the Editor: Venous Thromboembolism Prophylaxis After Pelvic and Acetabular Fractures: A Survey of Orthopaedic Surgeons' Current Practices.
Authors: Lim P, Scolaro J PMID: 32852332 [PubMed - as supplied by publisher] (Source: The Journal of the American Academy of Orthopaedic Surgeons)
Source: The Journal of the American Academy of Orthopaedic Surgeons - August 28, 2020 Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research

Factors Associated With Perioperative Transfusion in Lower Extremity Revision Arthroplasty Under a Restrictive Blood Management Protocol.
DISCUSSION: Patients with preoperative anemia, those undergoing revision TJA because of infection, those who did not receive TXA, and those undergoing more complex TJA procedures may have greater odds of requiring ABT. We recommend preoperative optimization of the health of these patients to reduce the need for ABT. LEVEL OF EVIDENCE: Level III, prognostic study. PMID: 32852330 [PubMed - as supplied by publisher] (Source: The Journal of the American Academy of Orthopaedic Surgeons)
Source: The Journal of the American Academy of Orthopaedic Surgeons - August 28, 2020 Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research

Major Orthopaedic Conference Abstract Publication: An Analysis of Abstracts Accepted for the AAOS Annual Meetings Between 2014 and 2017.
Authors: Le R, Anderson A, Chalmers CE, Scolaro JA, Lee YP, Bhatia N Abstract INTRODUCTION: The American Academy of Orthopaedic Surgeons (AAOS) Annual Meeting provides an opportunity for clinicians to attain the most recent advancements in the orthopaedic field. However, the most recent study analyzing publication rates from the 2001 Annual Meeting determined that only 49% of the podium and poster abstracts were eventually published. The purpose of this study was to determine the publication rate, likelihood of publication based on the presentation format, and time to publication for abstracts presented at the 2014...
Source: The Journal of the American Academy of Orthopaedic Surgeons - August 28, 2020 Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research

Listen and Change
Publication date: September 2020Source: Journal of the Academy of Nutrition and Dietetics, Volume 120, Issue 9Author(s): Linda T. Farr (Source: Journal of the Academy of Nutrition and Dietetics)
Source: Journal of the Academy of Nutrition and Dietetics - August 28, 2020 Category: Nutrition Source Type: research

Relative Age Effect in Russian Elite Hockey
The objective of this research was to study RAE prevalence in Russian elite ice hockey, which for years has been holding leading positions in global ice hockey. To estimate RAE prevalence, birthdates of recruits of leading ice hockey academies, players of the leading junior and adult teams, and most successful Russian-born National Hockey League (worlds' strongest ice hockey league) players were identified (n = 2,285). A high prevalence of RAE was identified. The number of players born in the first half of the year was higher than those born later in the year—65.5 and 34.5%, respectively. The RAE prevalence was high ...
Source: Journal of Strength and Conditioning Research - August 28, 2020 Category: Sports Medicine Tags: Original Research Source Type: research

Influence of Training Schedules on Objective Measures of Sleep in Adolescent Academy Football Players
Brown, GA, Veith, S, Sampson, JA, Whalan, M, and Fullagar, HHK. Influence of training schedules on objective measures of sleep in adolescent academy football players. J Strength Cond Res 34(9): 2515–2521, 2020—Football academy settings may pose risks to adolescent athletes achieving sufficient sleep because of the contextual challenges these players face (e.g., psychosocial pressure, changes in training, competition, and academic stress). Given the importance of sleep to overall health as well as physical athletic development and injury risk, this study aimed to investigate whether differences in training sched...
Source: Journal of Strength and Conditioning Research - August 28, 2020 Category: Sports Medicine Tags: Original Research Source Type: research

Reappraisal of Gestational Weight Gain Recommendations in Obese Pregnant Women: A Population-Based Study of 337,590 Births
Conclusion: The prevalence of maternal obesity has risen in Belgium between 2009 and 2014. Current GWG guidelines, based on historic observational data, are probably too liberal for class II and III obese women in which better outcomes are being predicted for lower weight gain than recommended.Obes Facts (Source: Obesity Facts)
Source: Obesity Facts - August 28, 2020 Category: Eating Disorders & Weight Management Source Type: research

Utility of confocal microscopy in the management of lentigo maligna and lentigo maligna melanoma
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - August 28, 2020 Category: Dermatology Authors: Payal Shah, Nicholas Gulati, Jennifer Stein, David Polsky, Nayoung Lee, Tracey N. Liebman Source Type: research

Trends in bibliometric indexes of the main dermatology journals (2009-2019).
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - August 28, 2020 Category: Dermatology Authors: H élio Amante Miot, Mayra Ianhez, Paulo Müller Ramos Source Type: research

Application of 3D Reflectance Confocal Microscopy: Melanocytic Proliferations as 3D Models
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - August 28, 2020 Category: Dermatology Authors: Katharine L. Hanlon, Lilia Correa-Selm, James M. Grichnik Source Type: research

Cutaneous Signs and Risk Factors for Ocular Melanoma
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - August 28, 2020 Category: Dermatology Authors: Katherine Ann McDonald, Hatem Krema, An-Wen Chan Source Type: research

The Magnitude of Increased US Melanoma Incidence Attributable to Ground-Level Ultraviolet Radiation Intensity Trends
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - August 28, 2020 Category: Dermatology Authors: Justin W. Marson, Graham H. Litchman, Darrell S. Rigel Source Type: research

Pharmacological Management of Spasticity in Children With Cerebral Palsy
Cerebral palsy (CP), a nonprogressive disease of the central nervous system, is the most common motor disability in childhood. Patients with CP often have a multitude of associated comorbidities, including impact on muscle tone. There are four main types of CP, with spastic as the most commonly diagnosed. Reduction in spasticity is important because it can affect not only the patient's quality of life, functional abilities, and well-being but also the lives of caregivers. The American Academy of Neurology and Child Neurology Society released a practice parameter regarding the pharmacological management of CP-related spasti...
Source: Journal of Pediatric Health Care - August 27, 2020 Category: Pediatrics Authors: Mary Reilly, Kayley Liuzzo, Allison B. Blackmer Tags: Pharmacology Continuing Education Source Type: research

Learning Active Implementation Frameworks: the role of implementation teams in a case study from Pakistan.
The objectives of this Program were to cultivate implementation science and practice competencies, and to support the development of national, community-based or institution-based implementation teams. The expected outcomes of this program included, further enhancement of the capacity of local health professionals in implementation science, systemic change and the effective use of innovations in practice at sub-national/regional levels. PMID: 32838706 [PubMed - in process] (Source: Global Health Action)
Source: Global Health Action - August 27, 2020 Category: International Medicine & Public Health Tags: Glob Health Action Source Type: research

Scandinavian Journal of Work, Environment and Health goes full open access
As of 1 January 2021, theScandinavian Journal of Work, Environment and Health (SJWEH) will become a full open access (OA) journal. Under the "gold" OA status, all new articles will be published as "unlocked content" on the journal ’s website. This makes the final version of an article freely accessible for everyone, and allows for distribution and adaptation as long as the authors are duly acknowledged as they retain the copyright. Online subscriptions will no longer be needed and thus terminated, whereas subscriptions for the printed journal will continue. Going full OA is a major step in the 45...
Source: Scandinavian Journal of Work, Environment and Health - August 27, 2020 Category: Occupational Health Tags: Editorial Source Type: research

Malignant Tumors of the Hand.
Authors: Chapman T, Athanasian E Abstract Primary malignant tumors in the hand are rare as compared to benign lesions; however, it is essential for orthopeadic surgeons to be familiar with their clinical presentation. The approach to working up a mass in the hand must be methodical and thorough, and clinicians must maintain high index of suspicion when evaluating these lesions. Successful identification and treatment of malignant tumors of the hand may include referral to a sarcoma center for staging, workup, and multidisciplinary treatment. Surgical treatment of malignant tumors in the hand is uniquely complicated...
Source: The Journal of the American Academy of Orthopaedic Surgeons - August 27, 2020 Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research

Council Page
(Source: Journal of the American Academy of Child and Adolescent Psychiatry)
Source: Journal of the American Academy of Child and Adolescent Psychiatry - August 27, 2020 Category: Psychiatry Source Type: research

Table of Contents
(Source: Journal of the American Academy of Child and Adolescent Psychiatry)
Source: Journal of the American Academy of Child and Adolescent Psychiatry - August 27, 2020 Category: Psychiatry Source Type: research

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This review is dedicated to the young adults with whom I ’ve had the privilege to work who have expressed fear of brutality by the police, and to parents who fear that their children would be labeled “criminals” because of the color of their skin. I also dedicate this to our colleagues who faced similar challenges to those that all of us faced to fo rge our child and adolescent psychiatry careers and additionally contended with discrimination, systemic racism, policing bias, and the threat of brutality. (Source: Journal of the American Academy of Child and Adolescent Psychiatry)
Source: Journal of the American Academy of Child and Adolescent Psychiatry - August 27, 2020 Category: Psychiatry Authors: Sarah Nayeem Tags: Book forum Source Type: research

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“We in the scientific community should keep an eye out for the Cades, and for the lithiums as well. Breakthroughs can still come from the unlikeliest of people and places.” (Source: Journal of the American Academy of Child and Adolescent Psychiatry)
Source: Journal of the American Academy of Child and Adolescent Psychiatry - August 27, 2020 Category: Psychiatry Authors: Howard Y. Liu Tags: Book forum Source Type: research

Implementing Logotherapy in Its Second Half-Century: Incorporating Existential Considerations Into Personalized Treatment of Adolescent Depression
Although biological processes have been directly targeted to substantial advantage in effective treatments for major depression, the evidence base for addressing potential “existential” contributions to depressive syndromes has lagged behind that related to other tractable mediators of the condition, such as cognitive bias, nonadaptive learned behavior, and variation in monoamine neurotransmission. Whether the experience of existential conflict is a cause or an ef fect of these phenomena is incompletely understood. Here, we provide a clinical update on knowledge surrounding a psychotherapeutic tradition that ad...
Source: Journal of the American Academy of Child and Adolescent Psychiatry - August 27, 2020 Category: Psychiatry Authors: W. Thomas Baumel, John N. Constantino Tags: Clinical perspectives Source Type: research

How Did We Get Here?
This month, Sarah Nayeem, an academic outpatient child and adolescent psychiatrist, based in Columbus, Ohio, reviews Michelle Alexander ’s The New Jim Crow: Mass Incarceration in the Age of Colorblindness. Alexander is a lawyer and legal scholar whose research features prominently in Ava DuVernay’s documentary 13th. The central thesis of “New Jim Crow,” published in a 10th anniversary edition this year, is that Americans mus t “reckon with the recurring cycles of racial reform, retrenchment and rebirth of caste-like systems that have defined our racial history since slavery.”2 From Nayee...
Source: Journal of the American Academy of Child and Adolescent Psychiatry - August 27, 2020 Category: Psychiatry Authors: Craigan Usher Tags: Book forum Source Type: research

Editorial Board
(Source: Journal of the American Academy of Child and Adolescent Psychiatry)
Source: Journal of the American Academy of Child and Adolescent Psychiatry - August 27, 2020 Category: Psychiatry Source Type: research

Youth Suicide: An Opportunity for Prevention
In the United States, youth suicide is a large and growing public health problem that contributes to health care costs, lost productivity, morbidity, and premature death. In 2017, an estimated 199,877 youths aged 10 to 24 years were treated in emergency departments in the United States for self-harm,1 and 7.4% of high school students reported that they attempted suicide one or more times in the past year.2 Suicide was the second leading cause of death among youths aged 10 to 24 years in 2017,1 and the suicide rate increased significantly for both male and female youths from 1999 to 2017.3 (Source: Journal of the American A...
Source: Journal of the American Academy of Child and Adolescent Psychiatry - August 27, 2020 Category: Psychiatry Authors: Allison Ertl, Alex E. Crosby, Janet M. Blair Tags: Commentary Source Type: research

13 Reasons Why: The Evidence Is in and Cannot Be Ignored
Decades of research overwhelmingly supports the public health necessity of safe, balanced, and responsible news media reporting on suicide.1,2 When news media follow recommendations for safe reporting, the risk of copycat suicide decreases.3 The Recommendations for Media Reporting on Suicide were developed by leading experts in suicide prevention and in collaboration with several international suicide prevention and public health organizations, schools of journalism, media organizations, and key journalists, as well as Internet safety experts (www.reportingonsuicide.org). The recommendations are based on more than 100 inte...
Source: Journal of the American Academy of Child and Adolescent Psychiatry - August 27, 2020 Category: Psychiatry Authors: Dan Reidenberg, Thomas Niederkrotenthaler, Mark Sinyor, Jeffrey A. Bridge, Benedikt Till Tags: Commentary Source Type: research

A reply to "Surgery versus combined treatment with curettage and imiquimod for nodular basal cell carcinoma: One-year results of a noninferiority, randomized, controlled trial.
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - August 27, 2020 Category: Dermatology Authors: Kelly Sinx Source Type: research

Effectiveness of Motivational Interviewing-Enhanced Behavior Therapy for Adolescents With Attention-Deficit/Hyperactivity Disorder: A Randomized Community-Based Trial
This study tests the effectiveness of parent-teen psychotherapy for adolescent ADHD (Supporting Teens ’ Autonomy Daily; STAND) versus Usual Care (UC) in four community clinics. (Source: Journal of the American Academy of Child and Adolescent Psychiatry)
Source: Journal of the American Academy of Child and Adolescent Psychiatry - August 27, 2020 Category: Psychiatry Authors: Margaret H. Sibley, Paulo A. Graziano, Stefany Coxe, Leonard Bickman, Pablo Martin Tags: New Research Source Type: research

ONS Guidelines ™ for Cancer Treatment-Related Skin Toxicity.
ONS Guidelines™ for Cancer Treatment-Related Skin Toxicity. Oncol Nurs Forum. 2020 Sep 01;47(5):539-556 Authors: Williams LA, Ginex PK, Ebanks GL, Ganstwig K, Ciccolini K, Kwong BK, Robison J, Shelton G, Strelo J, Wiley K, Maloney C, Moriarty KA, Vrabel M, Morgan RL Abstract BACKGROUND: Management of cancer treatment-related skin toxicities can minimize treatment disruptions and improve patient well-being. OBJECTIVES: This guideline aims to support patients and clinicians in decisions regarding management of cancer treatment-related skin toxicities. METHODS: A panel developed a guideli...
Source: Oncology Nursing Forum - August 26, 2020 Category: Nursing Authors: Williams LA, Ginex PK, Ebanks GL, Ganstwig K, Ciccolini K, Kwong BK, Robison J, Shelton G, Strelo J, Wiley K, Maloney C, Moriarty KA, Vrabel M, Morgan RL Tags: Oncol Nurs Forum Source Type: research

Network Pharmacology to Identify the Pharmacological Mechanisms of a Traditional Chinese Medicine Derived from Trachelospermum jasminoides in Patients with Rheumatoid Arthritis.
CONCLUSIONS Our study illustrated that T. jasminoides alleviates RA through the interleukin-17 signaling pathway, the tumor necrosis factor signaling pathway, and other immune and inflammatory-related processes. It also may exert effects in regulating cell differentiation and potentially has anti-anxiety, anti-depression, and estrogen-like effects. PMID: 32840241 [PubMed - in process] (Source: Medical Science Monitor)
Source: Medical Science Monitor - August 26, 2020 Category: Research Tags: Med Sci Monit Source Type: research

Racial justice and HIV prevention
No abstract available (Source: Journal of the American Academy of Physician Assistants)
Source: Journal of the American Academy of Physician Assistants - August 26, 2020 Category: Primary Care Tags: Letter to the Editor Source Type: research

Planting season
No abstract available (Source: Journal of the American Academy of Physician Assistants)
Source: Journal of the American Academy of Physician Assistants - August 26, 2020 Category: Primary Care Tags: The Art of Medicine Source Type: research

What is causing this patient's chest pain?
No abstract available (Source: Journal of the American Academy of Physician Assistants)
Source: Journal of the American Academy of Physician Assistants - August 26, 2020 Category: Primary Care Tags: A Difficult Diagnosis Source Type: research

Necrotizing fasciitis
No abstract available (Source: Journal of the American Academy of Physician Assistants)
Source: Journal of the American Academy of Physician Assistants - August 26, 2020 Category: Primary Care Tags: Diagnostic Imaging Review Source Type: research

Pyelonephritis
No abstract available (Source: Journal of the American Academy of Physician Assistants)
Source: Journal of the American Academy of Physician Assistants - August 26, 2020 Category: Primary Care Tags: Quick Recertification Series Source Type: research

Recognizing and responding to sex-trafficked minors in the healthcare setting
Nearly 6,100 reports of sex trafficking were made to the United States Human Trafficking Hotline in 2017; 29% of those reports involved minors. Physician assistants (PAs), especially those working in emergency medicine and primary care, are among the few frequently accessed healthcare providers who have the opportunity for a private conversation with a sex trafficking victim or survivor. PAs must be able to recognize the risk factors and signs of trafficking and respond in a trauma-informed, survivor-centered manner. Connecting trafficking victims, survivors, and at-risk youth with wraparound services is critical to their ...
Source: Journal of the American Academy of Physician Assistants - August 26, 2020 Category: Primary Care Tags: Special Article Source Type: research

Emerging practices in onboarding programs for PAs: Program content
Conclusions: These common content areas may provide a starting point for organizations designing onboarding programs for their unique organizations. (Source: Journal of the American Academy of Physician Assistants)
Source: Journal of the American Academy of Physician Assistants - August 26, 2020 Category: Primary Care Tags: Original Research Source Type: research

Fecal microbiota transplantation in the treatment of Crohn disease
This article explains FMT and how it effectively targets the gut microbiota changes associated with the pathogenesis of Crohn disease. (Source: Journal of the American Academy of Physician Assistants)
Source: Journal of the American Academy of Physician Assistants - August 26, 2020 Category: Primary Care Tags: Review Article Source Type: research

Iliac vein stent migration with extensive cardiac damage in a patient with May-Thurner syndrome
This article describes a patient whose stent embolized completely to the right ventricle, destroying most structures in its path. (Source: Journal of the American Academy of Physician Assistants)
Source: Journal of the American Academy of Physician Assistants - August 26, 2020 Category: Primary Care Tags: Case Report Source Type: research

A patient with shortness of breath after total hip replacement
This article focuses on a minimally symptomatic patient with a history of hip fracture and total hip replacement who was found to have a saddle PE. (Source: Journal of the American Academy of Physician Assistants)
Source: Journal of the American Academy of Physician Assistants - August 26, 2020 Category: Primary Care Tags: Case Report Source Type: research

Cme post-test
No abstract available (Source: Journal of the American Academy of Physician Assistants)
Source: Journal of the American Academy of Physician Assistants - August 26, 2020 Category: Primary Care Tags: Post-Test Source Type: research

Infectious disease considerations in immunocompromised patients
This article describes the pathophysiology of immunosuppression in five common immunocompromised states—asplenia, HIV infection, solid organ transplant, biologic use, and cancer—as well as specific infectious risks and considerations for affected patients and how to manage them. (Source: Journal of the American Academy of Physician Assistants)
Source: Journal of the American Academy of Physician Assistants - August 26, 2020 Category: Primary Care Tags: CME: Immunology Source Type: research

Identifying and managing bronchiolitis
This article reviews the epidemiology, clinical presentation, and treatment of bronchiolitis. (Source: Journal of the American Academy of Physician Assistants)
Source: Journal of the American Academy of Physician Assistants - August 26, 2020 Category: Primary Care Tags: CME: Pediatrics Source Type: research

Psychometric Evaluation of Patient-reported Outcomes Measurement Information System Physical Function Computer Adaptive Testing in Minimally Invasive Lumbar Spine Surgery: An Analysis of Responsiveness, Coverage, Discriminant Validity, and Concurrent Validity.
CONCLUSIONS: Although the PROMIS-PF showed lower responsiveness than the ODI, particularly in the decompression subgroup, it demonstrated discriminant validity preoperatively and postoperatively, convergent validity with ODI, and better coverage than ODI. These findings suggest that the PROMIS-PF CAT demonstrates reasonable psychometric properties and may be a good surrogate for the ODI. PMID: 32833390 [PubMed - in process] (Source: The Journal of the American Academy of Orthopaedic Surgeons)
Source: The Journal of the American Academy of Orthopaedic Surgeons - August 26, 2020 Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research