An Intra-Hospital Spread of Colistin-Resistant < em > K. pneumoniae < /em > Isolates-Epidemiological, Clinical, and Genetic Analysis
Conclusions: The study describes a within-hospital spread of two clones of COLr CR-Kp with a 60% mortality rate. Clone A isolates were coproducers of NDM-like and OXA-48-like enzymes and had mgrB-mediated colistin resistance. Clone B isolates had only OXA-48-like enzymes and intact mgrB genes. No plasmid-mediated resistance was found. The extremely high mortality rate and limited treatment options warrant strict measures to prevent outbreaks.PMID:38541237 | DOI:10.3390/medicina60030511 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Georgi Popivanov Rumyana Markovska Ivanka Gergova Marina Konaktchieva Roberto Cirocchi Kirien Kjossev Ventsislav Mutafchiyski Source Type: research

Dermatologic findings associated with semaglutide use: a scoping review
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - March 28, 2024 Category: Dermatology Authors: Megan M. Tran, Fatima N. Mirza, Adrian C. Lee, Hayley Goldbach, Tiffany J. Libby, Oliver J. Wisco Source Type: research

Efficacy and safety of tildrakizumab for the treatment of moderate-to-severe plaque psoriasis of the scalp: A multicenter, randomized, double-blind, placebo-controlled, Phase 3b study
Scalp psoriasis is common and difficult to treat. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - March 28, 2024 Category: Dermatology Authors: Kurt Gebauer, Lynda Spelman, Paul S. Yamauchi, Jerry Bagel, Tushar Nishandar, Michael Crane, Iris Kopeloff, Mudgal Kothekar, Siu-Long Yao, Howard L. Sofen Source Type: research

Elevation of Creatine Phosphokinase in Moderate-Severe Atopic Dermatitis is Associated with the use of JAK inhibitors but not Dupilumab: A Systematic Review and Meta-Analysis.
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - March 28, 2024 Category: Dermatology Authors: Daud Manzar, Emmanuel Suntres, Nikhil Nair, Yash Patel, Mohannad Abu-Hilal Source Type: research

Drug Survival of Biologics in Hidradenitis Suppurativa: A Systematic Review and Meta-Analysis
(Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - March 28, 2024 Category: Dermatology Authors: James P. Pham, Nana A.L. Rosen ΓΈ, Gabriele Roccuzzo, Ryan C. Saal, Alexander Egeberg, Hans C. Ring, John W. Frew Source Type: research