The Most Promising Cancer-Fighter In Years

For a while now, I’ve been recommending a powerful antioxidant with the unpronounceable name, pyrroloquinoline quinine – or PQQ for short. And although I recommend this compound to almost everyone who comes to see me at my wellness clinic in South Florida because of its energy-giving qualities, I’ve also observed its extraordinary power to fight cancer. For years, I’ve seen PQQ work wonders with my older patients, because it keeps you feeling young by giving your cells extra energy. PQQ was first discovered back in 1979 by a team of Japanese scientists, who knew little about the substance, except that it seemed to play some role in ensuring the propagation of our species. Then further research revealed the impact of PQQ on the output of energy from mitochondria, the microscopic power plants inside each of your cells. Since, researchers have discovered many important roles of PQQ on the body’s cellular processes – but the understanding is not yet complete. PQQ has even been discovered in interstellar stardust, which has led some scientists to theorize about its role in the evolution of life on Earth. In one study, PQQ prevented a significant number of heart cells from self-destructing when scientists deprived them of oxygen and glucose.1 In another study, researchers applied toxic hydrogen peroxide to cells taken from the jelly-like core of the spine. And a significant number of cells were saved by doses of PQQ.2 In yet another study, resear...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Anti-Aging antioxidants Cancer energy Source Type: news

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Publication date: 15 January 2019Source: Journal of Molecular Structure, Volume 1176Author(s): S. Murugavel, C. Ravikumar, G. Jaabil, Ponnusamy AlagusundaramAbstractPrevious research studies confirm that molecules containing 1,2,3-triazole moiety are potential anticancer agents which elevates effectiveness and reduces drug resistance. Present study was aimed to evaluate the anticancer activity of the synthesized novel title compound 2-(1-benzyl-5-methyl-1H-1,2,3-triazol-4-yl)-4-(2-chlorophenyl)-6-methoxypyridine (BTCP). The structural and spectral characteristics of BTCP were studied and compared with DFT results. NBO, HOM...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
Publication date: Available online 19 September 2018Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Giacomo Monzio Compagnoni, Giulio Kleiner, Andreina Bordoni, Francesco Fortunato, Dario Ronchi, Sabrina Salani, Marianna Guida, Corrado Corti, Irene Pichler, Christian Bergamini, Romana Fato, Maria Teresa Pellecchia, Annamaria Vallelunga, Francesca Del Sorbo, Antonio Elia, Chiara Reale, Barbara Garavaglia, Gabriele Mora, Alberto Albanese, Filippo CogiamanianAbstractMultiple System Atrophy is a severe neurodegenerative disorder which is characterized by a variable clinical presentation and a...
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - Category: Molecular Biology Source Type: research
CONCLUSIONS: Contrary to our hypothesis, there was a tendency for older adults to have better outcomes than younger, independent of the diagnostic criteria applied. PMID: 30230916 [PubMed - as supplied by publisher]
Source: Brain Injury - Category: Neurology Tags: Brain Inj Source Type: research
Publication date: Available online 19 September 2018Source: Advances in Biological RegulationAuthor(s): Mariana L. Oliveira, Padma Akkapeddi, Daniel Ribeiro, Alice Melão, João T. BarataAbstractInterleukin 7 (IL-7) and its receptor (IL-7R, a heterodimer of IL-7Rα and γc) are essential for normal lymphoid development. In their absence, severe combined immunodeficiency occurs. By contrast, excessive IL-7/IL-7R-mediated signaling can drive lymphoid leukemia development, disease acceleration and resistance to chemotherapy. IL-7 and IL-7R activate three main pathways: STAT5, PI3K/Akt/mTOR and MEK/Erk, u...
Source: Advances in Biological Regulation - Category: Biology Source Type: research
Publication date: January 2019Source: Biomedical Signal Processing and Control, Volume 47Author(s): Jijun Tong, Yingjie Zhao, Peng Zhang, Lingyu Chen, Lurong JiangAbstractAn automatic brain tumor segmentation method based on texture feature and kernel sparse coding from FLAIR (fluid attenuated inversion recovery) contrast-enhanced MRIs (magnetic resonance imaging) is presented in this paper. First, the MRIs are pre-processed to reduce noise, enhance contrast and correct the intensity non-uniformity. Then sparse coding is performed on the first order and second order statistical eigenvector extracted from original MRIs whic...
Source: Biomedical Signal Processing and Control - Category: Biomedical Science Source Type: research
Publication date: Available online 19 September 2018Source: MitochondrionAuthor(s): Arianna Di Stadio, Corrado Angelini
Source: Mitochondrion - Category: Biochemistry Source Type: research
Simon Thompson, 32, from Kent, was rushed to hospital when a 'dental abscess' failed to improve despite antibiotics. He was later diagnosed with advanced Non Hodgkin's lymphoma.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
In conclusion, the analyses do not permit us to predict the trajectory that maximum lifespans will follow in the future, and hence provide no support for their central claim that the maximum lifespan of humans is "fixed and subject to natural constraints". This is largely a product of the limited data available for analysis, owing to the challenges inherent in collecting and verifying the lifespans of extremely long-lived individuals. A reply from Jan Vijg's research group The authors of the accompanying comment disagree with our finding of a limit to human lifespan. Although we thank them for a...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
This study is the first to show that downregulation of PAPP-A expression in adult mice can significantly extend life span. Importantly, this beneficial longevity phenotype is distinct from the dwarfism of long-lived PAPP-A KO, Ames dwarf, Snell dwarf and growth hormone receptor (GHR) KO mice with germ-line mutations. Thus, downregulation of PAPP-A expression joins other treatment regimens, such as resveratrol, rapamycin and dietary restriction, which can extend life span when started in mice as adults. In a recent study, inducible knockdown of the GHR in young adult female mice increased maximal, but not median, lif...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
This study assessed the prevalence of grey hair in patients with coronary artery disease and whether it was an independent risk marker of disease. This was a prospective, observational study which included 545 adult men who underwent multi-slice computed tomography (CT) coronary angiography for suspected coronary artery disease. Patients were divided into subgroups according to the presence or absence of coronary artery disease, and the amount of grey/white hair. The amount of grey hair was graded using the hair whitening score: 1 = pure black hair, 2 = black more than white, 3 = black equals white, 4 = white more t...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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