Prevalence of autoimmune diseases and clinical significance of autoantibody profile: data from National Institute of Hygiene in Rabat, Morocco.
CONCLUSION: Our study shows the diagnostic value of auto antibodies in AIDs. It would be interesting to carry out prospective studies on each pathology separately, in order to fill the classic vagaries of the retrospective study and objectively estimate the prevalence in different AIDs. These data on the prevalence of each autoimmune disease are valuable for the public health system. PMID: 30807792 [PubMed - as supplied by publisher]
CONCLUSION: The small amount of evidence that is currently available suggests that presbycusis is underdiagnosed and under- treated in Germany. Early detection by physicians of all specialties, followed in each case by a specialized differential diagnostic evaluation, is a desirable goal. PMID: 31196393 [PubMed - in process]
Authors: López-Sánchez GN, Dóminguez-Pérez M, Uribe M, Nuño-Lámbarri N Abstract Acute-on-chronic liver failure (ACLF) is a life-threatening condition characterized by a rapid deterioration of previously well-compensated chronic liver diseases. One of the main obstacles in ACLF is the lack of knowledge of the pathogenesis and specific broad-spectrum treatments. An excessive systemic inflammatory response has been proposed to explain the pathogenesis of ACLF; this hypothesis involves stellate cells, which are implicated in many liver homeostatic functions that include vitamin...
Authors: Guney Varal I, Dogan P, Gorukmez O, Dorum S, Akdag A Abstract Introduction: Glutathione synthetase (GSS) deficiency is an autosomal recessive disorder (frequency A, p.Arg267Gln in the GSS gene of this patient. Femur agenesis had not previously been associated with GSS. PMID: 31198081 [PubMed - as supplied by publisher]
This article discusses the medications used to treat AIBD prior to conception, during pregnancy, and while breastfeeding, as well as highlights those that are contraindicated. The preferred approach to management in these patients is also discussed. Additionally, we present the available information regarding neonates of mothers with a diagnosis of AIBD, including the likelihood, identification, and management of neonatal blistering and the effects from medication exposure in utero. PMID: 31195784 [PubMed - as supplied by publisher]
CONCLUSIONS: During antihypertensive treatment, several dermatological reactions may occur. Clinicians should inform their patients of the increased risk of cutaneous lesions associated with the use of these drugs, and perform periodic examination of the skin. PMID: 31195782 [PubMed - as supplied by publisher]
ConclusionsMultiple site of infection ,sever osteomylitis, and delay in fever response consolidated the fact of high virulence of salmonella in SCD patients. We do not encounter significant resistant rate to both quinolone and cephalosporin.
Conclusions: Ocular involvement (mostly uveitis) in juvenile inflammatory arthritis and other pediatric rheumatic diseases varied between 3% and 50% depending on the underlying condition; and was highest in pediatric Bechet’s. In JIA, the highest frequency of uveitis was in oligoarticular JIA; with anterior uveitis being the most frequent type of uveitis. There was variation geographically for uveitis in JIA.
When consumed by women before and during pregnancy, folic acid, a B vitamin, may help prevent neural tube defects (NTDs).
Publication date: Available online 14 June 2019Source: Brain, Behavior, and ImmunityAuthor(s): Alessandra Borsini, Carmine M. Pariante, Patricia A. Zunszain, Nilay Hepgul, Alice Russell, Zuzanna Zajkowska, Valeria Mondelli, S. Sandrine ThuretAbstractInterferon (IFN)-α treatment for hepatitis C virus (HCV) is a well-recognized clinical model for inflammation-induced depression, but the brain cellular mechanisms underlying these effects are still not clear. Previous data reported an alteration in peripheral levels of inflammatory and neuroplasticity markers in the blood of depressed versus non-depressed patients. We in...
ConclusionAlthough a randomized clinical trial is needed, this systematic review tends to support daptomycin usage for bone and joint infections.
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