How to Plan and Carry Out a Simple Self-Experiment, a Single Person Trial of a Mitochondrially Targeted Antioxidant

The objective here is a set of tests that (a) match up to the expected outcome based on human trials of mitochondrially targeted antioxidants, and (b) that anyone can run without the need to involve a physician, as that always adds significant time and expense. These tests are focused on the cardiovascular system, particularly measures influenced by vascular stiffness, and some consideration given to parameters relevant to oxidative stress and the development of atherosclerosis. A standard blood test, with inflammatory markers. An oxidized LDL cholesterol assessment. Resting heart rate and blood pressure. Heart rate variability. Pulse wave velocity. Biological age assessment via DNA methylation patterns. The cardiovascular health measures in that list are those that are impacted by changes in the elasticity or functional capacity of blood vessels, such as would be expected to occur to some degree in a treatment that compensated in some way for the effects of aging on the smooth muscule cells in blood vessel walls - as is thought to be the case for mitochondrially targeted antioxidants. Positive change of the average values in most of these metrics are achievable with significant time and effort spent in physical training, so movement in the numbers in a short period of time as the result of a treatment should be an interesting data point. Bloodwork There exist online services such as WellnessFX where one can order up a blood test and then head off...
Source: Fight Aging! - Category: Research Authors: Tags: Self-Experimentation Source Type: blogs