Drugs, Alcohol and Suicide Are Causing Life Expectancy in America to Drop Dramatically

U.S. life expectancy has decreased for the second year in a row, and an editorial in the BMJ points to three contributing factors: drugs, alcohol and suicides, particularly among middle-age white Americans and those living in rural communities. The authors of the paper paint a bleak picture of the problems facing much of the United States today, but the authors say that policies that bolster the middle-class can help reverse the trend. The recent drop in life expectancy is alarming, the editorial states, “because life expectancy has risen for much of the past century in developed countries, including in the U.S.” Compared to gains made by other developed countries, however, the United States began to lose ground in the 1980s. Americans’ life expectancy plateaued in 2012, and now is headed in the opposite direction. “Something is amiss in the health of Americans, and the country, on a population level, is sick and dying earlier,” says the editorial’s lead author, Steven Woolf, director of the Center on Society and Health at Virginia Commonwealth University. “Quite simply, it means that babies born today are likely to live a shorter life than those born a year or two ago.” As to why U.S. life expectancy is declining, Woolf says that many people point toward the current opioid epidemic. “That’s certainly a big factor, but it’s also a larger problem that’s been going on for decades,” he says. “W...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime onetime public health Source Type: news

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Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
Objective Knee osteoarthritis (OA) has a significant impact on quality of life (QOL). Although QOL is generally thought to diminish over time, it is unknown whether different patient groups demonstrate unique patterns of change in QOL. We sought to identify and characterize QOL trajectories in knee OA. Design This prospective cohort study included 1013 individuals with symptomatic knee OA from the osteoarthritis initiative. We used group-based trajectory modeling to identify distinct temporal patterns of change in the Knee Injury and Osteoarthritis Outcome Score QOL subscale for 8 yrs. Baseline covariates included age...
Source: American Journal of Physical Medicine and Rehabilitation - Category: Rehabilitation Tags: Original Research Articles Source Type: research
Conclusions This multicomponent prospective memory training improved prospective memory performance and activities of daily living and reduce negative mood (depression) and anxiety levels among healthy older adults.
Source: American Journal of Physical Medicine and Rehabilitation - Category: Rehabilitation Tags: Original Research Articles Source Type: research
Capillary Biomedical is looking to develop a safer more reliable and accurate insulin infusion device. The Irvine, CA-based company has closed on $2.9 million in a series seed financing to help get its SteadiSet infusion set on the market. The Series Seed financing involved several Angel groups, including Tech Coast Angels, New York Angels, HBS Alumni Angels of New York, Pasadena Angels and the Mass Medical Angels, making the financing one of the broadest and most successful syndications among Angel investor groups. Other investors included the ACE Fund, PA Fund and NYA Fund. Financing proceeds will be used for clinical tr...
Source: MDDI - Category: Medical Devices Authors: Tags: Business Tubing Source Type: news
Publication date: 18–24 August 2018Source: The Lancet, Volume 392, Issue 10147Author(s): Margaret McCartney
Source: The Lancet - Category: General Medicine Source Type: research
Publication date: 18–24 August 2018Source: The Lancet, Volume 392, Issue 10147Author(s): Rachael Davies
Source: The Lancet - Category: General Medicine Source Type: research
This study is registered with ClinicalTrials.gov, number NCT02453711.FindingsBetween Oct 1, 2015, and Feb 11, 2016, 957 individuals were randomly assigned (102–103 participants per active treatment group and 136 in the pooled placebo group). Mean baseline characteristics included age 47 years, bodyweight 111·5 kg, and BMI 39·3 kg/m2. Bodyweight data were available for 891 (93%) of 957 participants at week 52. Estimated mean weight loss was −2·3% for the placebo group versus −6·0% (0·05 mg), −8·6% (0·1 mg), −11·6% (0·2 mg), −1...
Source: The Lancet - Category: General Medicine Source Type: research
Man arrested in connection with synthetic marijuana overdoses at Connecticut park
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
ConclusionsOur results identify a novel PDX1 stress inducible complex (es) that regulates expression of stress and apoptosis genes to govern β cell survival.Graphical abstract
Source: Molecular Metabolism - Category: Endocrinology Source Type: research
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Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
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