Compound Interest: Assessing the Effects of Chemical Mixtures

This study … gives the field a new perspective on how to approach the question of adequately and accurately describing how the different chemicals in a mixture can exert biological effects,” says Gabriel Knudsen, a toxicologist at the National Cancer Institute, who was not involved in the study. Knudsen says he hopes that applying this new “mixtures” approach can help inform agencies tasked with setting and enforcing chemical regulations. “More mixtures studies like this one could help shape more well-informed and useful regulations for chemicals that are encountered by people every day,” he says. Lindsey Konkel is a New Jersey-based journalist who reports on science, health, and the environment. References 1. Pollock T, Mantella L, Reali V, deCatanzaro D. 2017. Influence of tetrabromobisphenol A, with or without concurrent triclosan, upon Bisphenol A and estradiol concentrations in mice. Environ Health Perspect 125(8):087014, PMID: 28886593, 10.1289/EHP1329. 2. U.S. Food and Drug Administration (FDA). 2017. 5 Things to Know about Triclosan. https://www.fda.gov/forconsumers/consumerupdates/ucm205999.htm [accessed 6 November 2017]. 3. FDA. 2016. Safety and effectiveness of consumer antiseptics; topic antimicrobial drug products for over-the-counter human use. Fed Reg 81(172):61106–61130. https://www.federalregister.gov/documents/2016/09/06/2016-21337/safety-and-effectiveness-of-consumer-antiseptics-topical-antim...
Source: EHP Research - Category: Environmental Health Authors: Tags: Science Selection Source Type: research