Bone health appears normal in transgender youth on hormone therapy
Bone mineral density (BMD) is only slightly below the normal average among transgender youth undergoing gender-affirming hormone therapy, according to a study by researchers at the University of Colorado in Aurora. A team of pediatricians analyzed results from dual energy x-ray absorptiometry (DEXA) scans in a group of transgender youth who participated in a trial at Children's Hospital Colorado between 2016 and 2018 to evaluate insulin sensitivity and body composition. The finding may be reassuring for youths undergoing gender-affirming care, noted lead author and medical student Micaela Roy. “Total body BMD Z-scores ...
Source: AuntMinnie.com Headlines - April 5, 2024 Category: Radiology Authors: Will Morton Tags: Digital X-Ray Source Type: news

Without RCT, FDA May Consider Approval Of A Cross-Sex Hormone For Gender-Affirming Care
The FDA may consider approval of the cross-sex hormone estradiol for gender incongruence in adults and minors based on an observational study and not an RCT with placebo. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - December 2, 2023 Category: Pharmaceuticals Authors: Joshua Cohen, Senior Contributor Tags: Healthcare /healthcare Innovation /innovation business pharma & standard Source Type: news

Links 11/17/2023
‘It was a way to share your musical experiences’: why cassette tapes flourished, and still endure Guardian (Kevin W) World’s Leading Theory on Alzheimer’s in Crisis After Major Drug Trials Fail ScienceAlert (Chuck L) "COVID-19 infection decreased testosterone levels and increased E2 (estradiol)…#guardian #kevinw #chuckl #usarmy #americanconservative #nikkihaley #dailymailfar #iraq #democrat #davidl (Source: Reuters: Health)
Source: Reuters: Health - November 17, 2023 Category: Consumer Health News Source Type: news

Evaluation of sex hormone levels in schizophrenia and depressive disorder - Kili ç N, Kuloğlu MM, Ustundag B.
In this study, we aimed to evaluate the levels of FSH, LH, estradiol, testosterone, progesterone, and prolactin in patients with schizophrenia and maj ör depressive disorder. Material and Method: Our study included a total of 80 female patients d... (Source: SafetyLit)
Source: SafetyLit - November 6, 2023 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Association between estradiol and human aggression: a systematic review and meta-analysis - Wang Y, Wang H, Cai J, Yu W, Zhang Y, Zhang Y, Tang Z.
This study aimed to investigate this relationship comprehensively. ... (Source: SafetyLit)
Source: SafetyLit - September 18, 2023 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Lupin Pharmaceuticals, Inc. Issues Voluntary Nationwide Recall of 2 Lots of Tydemy ™ (Drospirenone, Ethinyl Estradiol and Levomefolate Calcium Tablets 3mg/0.03mg/0.451mg and Levomefolate Calcium Tablets 0.451mg) Due to Out of Specification (OOS) Results at the 12-month Stability Time Point
Lupin Pharmaceuticals Inc. (Lupin) is voluntarily recalling two (2) lots of Tydemy (Drospirenone, Ethinyl Estradiol and Levomefolate Calcium Tablets 3mg/0.03mg/0.451 mg and Levomefolate Calcium Tablets 0.451 mg) to the patient (consumer/user) level due to out of specification (OOS) test results at t (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 1, 2023 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Lupin Pharmaceuticals, Inc. Issues Voluntary Nationwide Recall of 2 Lots of TydemyTM (Drospirenone, Ethinyl Estradiol and Levomefolate Calcium Tablets 3mg/0.03mg/0.451mg and Levomefolate Calcium Tablets 0.451mg) Due to Out of Specification (OOS) Results at the 12-month Stability Time Point
Lupin Pharmaceuticals Inc. (Lupin) is voluntarily recalling two (2) lots of Tydemy (Drospirenone, Ethinyl Estradiol and Levomefolate Calcium Tablets 3mg/0.03mg/0.451 mg and Levomefolate Calcium Tablets 0.451 mg) to the patient (consumer/user) level due to out of specification (OOS) test results at t (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - July 31, 2023 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Fostemsavir and Ethinyl Estradiol Drug Interaction Fostemsavir and Ethinyl Estradiol Drug Interaction
This article provides guidance regarding the co-administration of fostemsavir with hormonal therapies containing ethinyl estradiol among people living with HIV.HIV Medicine (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - June 16, 2023 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

Gut Bacterium Linked to Depression in Premenopause
The opportunistic pathogen Klebsiella aerogenes degrades estradiol and induces depressive-like behavior in mice, a study finds. (Source: The Scientist)
Source: The Scientist - March 17, 2023 Category: Science Tags: News & Opinion Source Type: news

Estrogen receptor alpha is required for metabolic health
<img width="100" src="https://factor.niehs.nih.gov/sites/niehs-factor/files/styles/large/public/2016/5/science-highlights/estrogen/thumb789551.jpg?itok=g7Q1muIZ" /><br /><p>Andrea Hevener, Ph.D., discussed the critical role of estradiol and estrogen receptor alpha for proper metabolic function in men and women.</p> (read more) (Source: Environmental Factor - NIEHS Newsletter)
Source: Environmental Factor - NIEHS Newsletter - February 3, 2023 Category: Environmental Health Source Type: news

Risk of thromboembolism in patients with COVID19 who are using hormonal contraception, Cochrane Library
Authors ' conclusions There are no comparative studies assessing risk of thromboembolism in COVID ‐19 patients who use hormonal contraception, which was the primary objective of this review. Very little evidence exists examining the risk of increased COVID‐19 disease severity for combined hormonal contraception users compared to non‐users of hormonal contraception, and the evidence that do es exist is of very low certainty. The odds of hospitalization for COVID‐19 positive users of combined hormonal contraceptives may be slightly decreased compared with those of hormonal contraceptive non‐users, but the evidence ...
Source: Current Awareness Service for Health (CASH) - January 20, 2023 Category: Consumer Health News Source Type: news

Psychosocial functioning in transgender youth after 2 years of hormones - Chen D, Berona J, Chan YM, Ehrensaft D, Garofalo R, Hidalgo MA, Rosenthal SM, Tishelman AC, Olson-Kennedy J.
BACKGROUND: Limited prospective outcome data exist regarding transgender and nonbinary youth receiving gender-affirming hormones (GAH; testosterone or estradiol). METHODS: We characterized the longitudinal course of psychosocial functioning during ... (Source: SafetyLit)
Source: SafetyLit - January 20, 2023 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Early Puberty Resulting From Excessive Smartphone Screen Time? Here ’s What This Study Found
Blue light exposure was associated with decreased levels of melatonin, increased levels of two major reproductive hormones (estradiol and luteinizing hormone), and changes in ovarian tissue that may be indicative of early onset of puberty in female rats. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - September 17, 2022 Category: Pharmaceuticals Authors: Bruce Y. Lee, Senior Contributor Tags: Healthcare /healthcare Innovation /innovation Science /science business pharma Source Type: news

Post-menopause HRT treatment to be sold in UK pharmacies
Estradiol tablets help treat the cause of vaginal dryness in women experiencing menopause. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - September 7, 2022 Category: Consumer Health News Source Type: news

Post-menopause HRT treatment to be sold over the counter in UK
Estradiol tablets help treat the cause of vaginal dryness in women experiencing menopause. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - September 7, 2022 Category: Consumer Health News Source Type: news