Surprising Research on Cannabis
Much of what we think we know about cannabis may soon change as a result of new research that uncovers some surprising facts. Indeed, the topic, which can be emotionally charged, is the focus of intense scientific study. Is cannabis good for you? Is it addictive? What long-term harms can use cause? The answers to these questions are multi-layered and not always clear-cut, which is why cannabis research continues with even more urgency. FACTS ON CANNABIS ADDICTION AND DEPENDENCE Current estimates are that one in 10 cannabis users will develop cannabis addiction or dependence. The potency of the delta-9-tetrahydrocannabinol ...
Source: Psych Central - November 9, 2018 Category: Psychiatry Authors: Suzanne Kane Tags: Addictions Habits Healthy Living Memory and Perception Miscellaneous Drugs Neuroscience Substance Abuse Source Type: news

Bijuva (Estradiol and Progesterone Capsules) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 8, 2018 Category: Drugs & Pharmacology Source Type: news

Janssen Issues Voluntary Nationwide Recall for one lot of ORTHO-NOVUM 1/35 and two lots of ORTHO-NOVUM 7/7/7 Due to Incorrect Veridate Dispenser Instructions
Janssen Pharmaceuticals, Inc. has initiated a voluntary recall of one lot of ORTHO-NOVUM 1/35 (norethindrone / ethinyl estradiol) Tablets and two lots of ORTHO-NOVUM 7/7/7 (norethindrone / ethinyl estradiol) Tablets to the pharmacy level. The patient information provided inside affected packages of ORTHO-NOVUM does not include the appropriate instructions for the Veridate dispenser. (Source: Food and Drug Administration)
Source: Food and Drug Administration - November 3, 2018 Category: Food Science Source Type: news

FDA Approves Bijuva (estradiol and progesterone) Capsules for the Treatment of Moderate to Severe Vasomotor Symptoms Due to Menopause
BOCA RATON, Fla.--(BUSINESS WIRE)--Oct. 29, 2018-- TherapeuticsMD, Inc, an innovative women ’s healthcare company, today announced that the United States Food and Drug Administration (FDA) has approved Bijuva (estradiol and progesterone) capsules,... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - October 29, 2018 Category: Drugs & Pharmacology Source Type: news

Sex, drugs and estradiol: why cannabis affects women differently
(Frontiers) Sex differences in cannabis use are beginning to be explained with the aid of brain studies in animals and humans. A new paper in Frontiers in Behavioral Neuroscience brings us up to date on progress. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 26, 2018 Category: International Medicine & Public Health Source Type: news

Estradiol and progesterone release may be different in epileptic female mice
In epileptic female mice the release of reproductive hormones estradiol and progesterone may be different due to changes in neuronal activty, according to research published ineNeuro.MedicalXpress (Source: Society for Endocrinology)
Source: Society for Endocrinology - October 15, 2018 Category: Endocrinology Source Type: news

Medical News Today: Existing drug may treat triple-negative breast cancer
Researchers have discovered that the drug estradiol may work as a new treatment for a type of triple-negative breast cancer, which is highly aggressive. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 9, 2018 Category: Consumer Health News Tags: Breast Cancer Source Type: news

Mayo researchers ID potential new treatment for one type of triple-negative breast cancer
(Mayo Clinic) Mayo Clinic researchers have identified the drug estradiol as a potential new treatment for a subset of women with triple-negative breast cancer. Their findings are published in the Proceedings of the National Academy of Sciences of the United States of America. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 4, 2018 Category: Cancer & Oncology Source Type: news

Medical News Today: What is an estradiol test and why is it used?
Estradiol is a form of the hormone estrogen, which plays a role in many aspects of growth and development. Doctors can measure estradiol levels with a blood test and may request one if they suspect any problems with sexual development or fertility. Learn more about the test's uses here, and what the results may mean. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 26, 2018 Category: Consumer Health News Tags: Endocrinology Source Type: news

Estradiol, Progesterone and CVD Risk in Postmenopausal Women Estradiol, Progesterone and CVD Risk in Postmenopausal Women
How might treatment with these hormones impact lipid parameters in postmenopausal women?Journal of the Endocrine Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 17, 2018 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health Journal Article Source Type: news

Annovera (Segesterone Acetate and Ethinyl Estradiol Vaginal System) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 16, 2018 Category: Drugs & Pharmacology Source Type: news

FDA Clears First Vaginal Ring for 1 Year of Birth Control FDA Clears First Vaginal Ring for 1 Year of Birth Control
Annovera (segesterone acetate and ethinyl estradiol vaginal system) is the first vaginal ring contraceptive approved that provides a full year of protection against unintended pregnancy.FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 10, 2018 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Alert Source Type: news

FDA Approves Annovera (segesterone acetate and ethinyl estradiol) Vaginal Contraceptive System
NEW YORK, Aug. 10, 2018 /PRNewswire/ -- The Population Council, a global nonprofit research organization, announced it has received U.S. Food and Drug Administration (FDA) approval for Annovera ™ (segesterone acetate and ethinyl estradiol vaginal... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - August 10, 2018 Category: Drugs & Pharmacology Source Type: news

FDA approves new vaginal ring for one year of birth control
FDA approved Annovera (segesterone acetate and ethinyl estradiol vaginal system), a combined hormonal contraceptive for women of reproductive age used to prevent pregnancy and is the first vaginal ring contraceptive that can be used for an entire year. (Source: Food and Drug Administration)
Source: Food and Drug Administration - August 10, 2018 Category: American Health Source Type: news

A moderate estradiol level enhances neutrophil number and activity in muscle after traumatic injury but strength recovery is accelerated - Le G, Novotny SA, Mader TL, Greising SM, Chan SSK, Kyba M, Lowe DA, Warren GL.
Estrogen has been shown to protect against skeletal muscle injury and a reduced inflammatory response has been suggested as a possible protective mechanism. There are, however, dissenting reports. Our objective was to conduct an unbiased, comprehensive stu... (Source: SafetyLit)
Source: SafetyLit - July 27, 2018 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Esclim (Estradiol Transdermal) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 26, 2018 Category: Drugs & Pharmacology Source Type: news

EstroGel (Estradiol Gel) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 20, 2018 Category: Drugs & Pharmacology Source Type: news

Estradiol to androstenedione ratios moderate the relationship between neurological injury severity and mortality risk after severe TBI - Ranganathan P, Kumar RG, Oh BM, Rakholia MV, Berga S, Wagner AK.
Early declines in gonadotropin production, despite elevated serum estradiol, among patients with severe traumatic brain injury (TBI) suggests amplified aromatization occurs post-injury. Our previous work identifies estradiol (E2) as a potent mortality mark... (Source: SafetyLit)
Source: SafetyLit - July 19, 2018 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Femcon Fe (Norethindrone and Ethinyl Estradiol Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - July 12, 2018 Category: Drugs & Pharmacology Source Type: news

Imvexxy (Estradiol Vaginal Inserts) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 27, 2018 Category: Drugs & Pharmacology Source Type: news

Norethindrone and Ethinyl Estradiol Tablets (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - June 20, 2018 Category: Drugs & Pharmacology Source Type: news

New study suggests ovarian hormone may make drug withdrawal symptoms worse for women
(Dickinson College) Researchers found that a form of the estrogen hormone can contribute to drug relapse in females by worsening withdrawal symptoms. The study looked at the interaction of the female sex hormone estradiol and methamphetamine. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 18, 2018 Category: International Medicine & Public Health Source Type: news

Testosterone May Be Key to CVD Risk in Women Testosterone May Be Key to CVD Risk in Women
A new analysis shows that higher testosterone levels and a higher ratio of testosterone to estradiol in postmenopausal women are associated with higher risk for cardiovascular disease.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 14, 2018 Category: Consumer Health News Tags: Cardiology News Source Type: news

Does stabilizing female hormones help lower suicide risk?
(University of Illinois at Chicago) A three-year, $750,000 grant from the National Institutes of Mental Health will help researchers determine whether the stabilization of ovarian hormones estradiol and progesterone can help lower symptoms associated with suicidality among females at risk for suicide. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 4, 2018 Category: International Medicine & Public Health Source Type: news

Oral Semaglutide Success; Lowest-Dose Vaginal Estradiol OK'd
(MedPage Today) -- News and commentary from the endocrinology world (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - June 1, 2018 Category: Urology & Nephrology Source Type: news

Postmenopausal Sex Hormone Levels Associated With Later CVD
FRIDAY, June 1, 2018 -- In postmenopausal women, higher testosterone/estradiol ratios are associated with increased risks for incident cardiovascular disease (CVD), coronary heart disease (CHD), and heart failure events, according to a study... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 1, 2018 Category: Pharmaceuticals Source Type: news

FDA Approves Imvexxy for Moderate to Severe Dyspareunia FDA Approves Imvexxy for Moderate to Severe Dyspareunia
The FDA approved estradiol vaginal inserts (Imvexxy, TherapeuticsMD) for moderate to severe dyspareunia.FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 31, 2018 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Alert Source Type: news

Hormone therapy may slow cognitive decline
A combination therapy of estradiol and progesterone may benefit cognitive function in postmenopausal women, a study inMenopause suggests.Science Daily (Source: Society for Endocrinology)
Source: Society for Endocrinology - May 31, 2018 Category: Endocrinology Source Type: news

TherapeuticsMD Announces FDA Approval of Imvexxy (estradiol vaginal inserts) for the Treatment of Dyspareunia Due to Menopause
BOCA RATON, Fla., May 30, 2018 /PRNewswire/ -- TherapeuticsMD, Inc. (NASDAQ: TXMD), an innovative women's healthcare company, today announced that the United States Food and Drug Administration (FDA) has approved Imvexxy (estradiol vaginal inserts)... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - May 31, 2018 Category: Drugs & Pharmacology Source Type: news

On second try, TherapeuticsMD lands FDA nod for vaginal capsule
TherapeuticsMD (NSDQ:TXMD) said today that it won FDA approval for its applicator-free estradiol vaginal capsule, TX-004HR. The soft-gel capsule is designed to treat moderate-to-severe vaginal pain experienced during sex, a symptom of vulvar and vaginal atrophy in women who have undergone menopause. Get the full story at our sister site, Drug Delivery Business News. The post On second try, TherapeuticsMD lands FDA nod for vaginal capsule appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - May 30, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Drug-Device Combinations Food & Drug Administration (FDA) Pharmaceuticals Regulatory/Compliance Wall Street Beat Women's Health TherapeuticsMD Source Type: news

Hormone Levels After Menopause Tied to Heart Risks (CME/CE)
(MedPage Today) -- Higher testosterone/estradiol ratio associated with CVD, CHD, and HF (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - May 29, 2018 Category: Endocrinology Source Type: news

Allergan Issues Nationwide Voluntary Recall of TAYTULLA ® Softgel Capsules 1mg/20mcg Sample Packs Due to Out of Sequence Capsules
Allergan plc (NYSE:AGN) today issued a voluntary recall in the US market of one lot (Lot# 5620706, Expiry May-2019) of TAYTULLA ® (norethindrone acetate and ethinyl estradiol capsules and ferrous fumarate capsules) 1mg/20mcg, 6x28 physicians sample pack, indicated for use by women to prevent pregnancy. Allergan recently identified, through a physician report, that four placebo capsules were placed out of order in a sample p ack of TAYTULLA. Specifically, the first four days of therapy had four non-hormonal placebo capsules instead of active capsules. (Source: Food and Drug Administration)
Source: Food and Drug Administration - May 29, 2018 Category: Food Science Source Type: news

Allergan Issues Nationwide Voluntary Recall of TAYTULLA ® Softgel Capsules 1mg/20mcg Sample Packs Due to Out of Sequence Capsules
Allergan plc (NYSE:AGN) today issued a voluntary recall in the US market of one lot (Lot# 5620706, Expiry May-2019) of TAYTULLA ® (norethindrone acetate and ethinyl estradiol capsules and ferrous fumarate capsules) 1mg/20mcg, 6x28 physicians sample pack, indicated for use by women to prevent pregnancy. Allergan recently identified, through a physician report, that four placebo capsules were placed out of order in a sample pack of TAYTULLA. Specifically, the first four days of therapy had four non-hormonal placebo capsules instead of active capsules. (Source: Food and Drug Administration)
Source: Food and Drug Administration - May 29, 2018 Category: Food Science Source Type: news

Osteoporosis Spinal Fractures; Vaginal Estradiol Tx; Diabetic Dog Lawsuit?
(MedPage Today) -- News and commentary from the endocrinology world (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - May 11, 2018 Category: OBGYN Source Type: news

Low - Dose Vaginal Estradiol Improves Menopause - Linked QOL
Significant improvement in total MENQOL scores, MENQOL sexual function domain for vaginal estradiol (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - May 10, 2018 Category: Psychiatry Tags: Family Medicine, Gynecology, Internal Medicine, Pharmacy, Psychiatry, Journal, Source Type: news

Low-Dose Vaginal Estradiol Improves Menopause-Linked QOL
THURSDAY, May 10, 2018 -- For menopausal women with moderate-severe vulvovaginal symptoms, treatment with low-dose vaginal estradiol is associated with improved menopause-related quality of life, according to a study published online May 7 in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 10, 2018 Category: Pharmaceuticals Source Type: news

Vaginal estradiol tablets outperform moisturizers when treating vulvovaginal problems
(The North American Menopause Society (NAMS)) Sex shouldn't hurt at any age, yet 75 percent of postmenopausal women report vaginal dryness, and up to 40 percent report pain with intercourse. A new study reports that vaginal estradiol tablets just might be what's needed to relieve vulvovaginal problems and improve overall quality of life. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 9, 2018 Category: International Medicine & Public Health Source Type: news

Lo-Zumandimine (Drospirenone and Ethinyl Estradiol Tablets) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - April 19, 2018 Category: Drugs & Pharmacology Source Type: news

TherapeuticsMD negotiates label for vaginal capsule after NDA resubmission
TherapeuticsMD (NSDQ:TXMD) is negotiating with the FDA over the proposed label for its investigational, applicator-free estradiol vaginal capsule, TX-004HR, the company reported today. The softgel capsule is designed to treat moderate-to-severe vaginal pain experienced during sex, a symptom of vulvar and vaginal atrophy in women who have undergone menopause. Get the full story at our sister site, Drug Delivery Business News. The post TherapeuticsMD negotiates label for vaginal capsule after NDA resubmission appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - April 11, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Drug-Device Combinations Food & Drug Administration (FDA) Pharmaceuticals Regulatory/Compliance Wall Street Beat Women's Health TherapeuticsMD Source Type: news

Impax Launches a Generic Version of Estrace(R) Cream (estradiol vaginal cream, USP, 0.01%)
BRIDGEWATER, N.J., April 6, 2018 -- (Healthcare Sales & Marketing Network) -- Impax Laboratories, Inc. (NASDAQ: IPXL), a specialty pharmaceutical company, today announced it has launched a generic version of Estrace® Cream (estradiol vaginal cream, US... Biopharmaceuticals, Generic, Product Launch Impax Laboratories, Perrigo Company, Estrace Cream, estradiol vaginal cream (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - April 6, 2018 Category: Pharmaceuticals Source Type: news

Vaginal Estradiol Offers Little Help for Postmenopausal Symptoms
(MedPage Today) -- Moisturizer no better than placebo gel, either (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - March 19, 2018 Category: OBGYN Source Type: news

First Documented Case of Transgender Woman Breastfeeding First Documented Case of Transgender Woman Breastfeeding
A transgender woman has fed her infant solely with breast milk for the first 6 weeks, after treatment with domperidone, estradiol, progesterone, and breast pumping.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 20, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Estradiol Therapy Mitigates Effects of Stress on Memory Estradiol Therapy Mitigates Effects of Stress on Memory
A new study examines how postmenopausal estradiol therapy may impact the effects of stress on cognition.Journal of Clinical Endocrinology & Metabolism (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 16, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Balcoltra (Levonorgestrel and Ethinyl Estradiol and Ferrous Bisglycinate Tablets ) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 7, 2018 Category: Drugs & Pharmacology Source Type: news

Kalliga (Desogestrel And Ethinyl Estradiol Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 31, 2018 Category: Drugs & Pharmacology Source Type: news

Perrigo Announces Final FDA Approval Of A Generic Version Of Estrace(R) Cream
DUBLIN, Jan. 24, 2018 -- (Healthcare Sales & Marketing Network) -- Perrigo Company plc (NYSE; TASE: PRGO) today announced it has received final approval from the U.S. Food and Drug Administration for the generic version of Estrace® Cream (estradiol va... Biopharmaceuticals, Generics, FDA Perrigo, Estrace, estradiol (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - January 24, 2018 Category: Pharmaceuticals Source Type: news

Norethindrone Acetate and Ethinyl Estradiol and Ferrous Fumarate (LOESTRIN Fe) Tablets (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - January 18, 2018 Category: Drugs & Pharmacology Source Type: news

Avion Pharmaceuticals announces approval of first NDA in the oral contraceptive category
ATLANTA, Jan. 17, 2018 -- (Healthcare Sales & Marketing Network) -- Avion Pharmaceuticals, LLC, the makers of the Prenate® line of prescription prenatal vitamins, received approval of its new drug application (NDA) for the oral contraceptive Balcoltra... Biopharmaceuticals, FDA Avion Pharmaceuticals, Balcoltra, levonorgestrel, ethinyl estradiol (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - January 17, 2018 Category: Pharmaceuticals Source Type: news

Avion Pharmaceuticals Announces FDA Approval of Balcoltra (levonorgestrel and ethinyl estradiol tablets and ferrous bisglycinate tablets) Oral Contraceptive
ATLANTA, Jan. 17, 2018 /PRNewswire/ -- Avion Pharmaceuticals, LLC, the makers of the Prenate ® line of prescription prenatal vitamins, received approval of its new drug application (NDA) for the oral contraceptive Balcoltra (levonorgestrel and... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - January 17, 2018 Category: Drugs & Pharmacology Source Type: news

Desogen (Desogestrel and Ethinyl Estradiol Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 16, 2018 Category: Drugs & Pharmacology Source Type: news