When Constipation Reaches its Breaking Point

​BY ALEJANDRO E. MACIAS; BILLY ZHANG; KRISTEN HUGHES; SHAMIM KHAN, MD; FRANCISCO JACOME, MDA 73-year-old man with a past medical history of hypertension, type 2 diabetes, and hyperlipidemia and a surgical history for a coronary artery bypass presented with sudden, severe lower abdominal pain. He characterized his pain as 8/10 and was tender to palpation.Laboratory studies showed a white blood cell count of 7.51 with a glucose of 759, no bands, a platelet count of 230,000, and a lactic acid level of 6.7. Urinalysis showed +5 ketones and a glucose count of greater than 500. An abdominal CT showed possible microperforations around the cecum. The patient also had electrocardiogram changes indicative of an abnormality in the inferior wall of the heart. The patient was given 1 g of ertapenem and 1 g of ceftriaxone, and was placed on a bicarbonate drip. The clinical impression at this point was shock (septic vs cardiac).The patient was taken emergently to the catheterization lab to rule out acute coronary artery disease. Severe three-vessel coronary artery disease, totally occluded third vein graft, and moderate to severe reduced left ventricular function with an ejection fraction of 30 to 35 percent were found. The patient was transferred to the intensive care unit, where he was evaluated by surgery. His blood pressures was in the 70s, and he was tachycardic and tachypneic. A central line was placed and dobutamine, levophed, and two liters of normal saline were administered with ...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research

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Authors: Al Balbeesi HO, Al Kawari HM, Al Tamimi AS, Al Mubarak I, Al Ibrahim KI, Divakar DD Abstract In the present study, the authors evaluated the association of canine impaction with different skeletal discrepancies in two planes of space (sagittal and vertical). Cephalometric and orthopantomographic radiographic images of 45 patients with one or more impacted canines were used in this retrospective study. Five radiographic morphologic parameters-ANB angle, canine angulation, angle between the Frankfort horizontal plane and the mandibular plane (FH-MP), Wits appraisal analysis, and axial inclination of the maxi...
Source: International Journal of Periodontics and Restorative Dentistry - Category: Dentistry Tags: Int J Periodontics Restorative Dent Source Type: research
Background: Despite the critical role that Emergency Medical Services (EMS) provides in the health care system, racial/ethnic treatment disparities in EMS remain relatively unexamined. Objective: To investigate racial/ethnic treatment disparities in pain assessment and pain medication administration in EMS. Research Design: A retrospective analysis was performed on 25,732 EMS encounters from 2015 to 2017 recorded in the Oregon Emergency Medical Services Information System using multivariate logistic regression models to examine the role of patient race/ethnicity in pain assessment and pain medication administration...
Source: Medical Care - Category: Health Management Tags: Original Articles Source Type: research
Conclusions: We found that perceived stigma in health care settings was a potential barrier to good health. Prior studies have illustrated that negative health outcomes are common for patients who avoid or delay care; thus, the unfortunate conclusion is that even in a diverse, heterogeneous community, stigma persists and may negatively affect well-being. Therefore, eliminating stigma in clinical settings should be a top priority for health care providers and public health professionals seeking to improve health equity.
Source: Medical Care - Category: Health Management Tags: Original Articles Source Type: research
No abstract available
Source: Medical Care - Category: Health Management Tags: Errata Source Type: research
[VOA] On the eve of World Diabetes Day, November 14, the World Health Organization is launching a new initiative it believes will allow greater access to life-saving insulin at lower prices for a greater number of people suffering from diabetes.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Abstract Retrospective analysis has already shown correlation between severe Chronic Periodontitis (CP) cases with human papiloma virus (HPV). Hence, we aimed to explore deep-seated infected granulation tissue removed during periodontal flap surgery procedures for residential bacterial species between HPV+ and HVP- CP cases, which may serve as good predisposition marker for oral cancer. All CP-granulation samples showed the prominence of Firmicutes, Proteobacteria, and Bacteroidetes phyla with an abundance of gram negative anaerobes, except Streptococcus. In Beta diversity nonmetric multidimensional scaling plot, ...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Abstract An important harmonization effort was produced by the scientific community to standardize both the preanalytical and interpretative phases of programmed death-ligand 1 (PD-L1) immunohistochemical (IHC) testing in non-small-cell lung cancer (NSCLC). This analysis is crucial for the selection of patients with advanced-stage tumors eligible for treatment with pembrolizumab and potentially with other anti-PD-1/PD-L1 checkpoint inhibitors. This multicentric retrospective study evaluated the reproducibility of PD-L1 testing in the Italian scenario both for closed and open platforms. In the evaluation of the wel...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Abstract Preeclampsia (PE) is termed as an obstetric issue that is characterized by hypertension (≧140/90 mm Hg), together with proteinuria following 20 weeks of pregnancy. Until today, PE still constitutes a severe threat to the lives of both the mothers and fetuses. In the past, long noncoding RNAs (lncRNAs) were considered as the transcriptional noise. However, some investigations have indicated that lncRNAs could be used as innovative indicators in PE. The current review aims to discuss the relationship between lncRNAs and PE in recent years. According to the retrieved data, we concluded that lncRNAs ...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Abstract Treatment of pilon fractures remains challenging due to the difficulty of fracture reduction and associated soft tissue complications. The aim of this study was to evaluate the pitfalls and strategies of posterior column reduction in the treatment of complex tibial pilon fractures (AO/OTA 43-C3). Thirteen AO/OTA classification 43-C3 type pilon fractures treated between January 2013 and January 2016 were retrospectively analyzed. Nine cases were treated by external fixation within 26 hours (range, 6-56 hours) after injury. The definitive open reduction and internal fixation (ORIF) was performed after the w...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
[News24Wire] Springbok star Faf de Klerk has pulled the national underpants out again to kick off the "#FafChallenge" - to get men to check their "crown jewels" for signs of testicular cancer.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
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