Role of Hydrocortisone, Fludrocortisone in Septic Shock Role of Hydrocortisone, Fludrocortisone in Septic Shock
Twenty years after abandoning hydro/fludro for septic shock, Dr Holley will use it again, with some reservations.Medscape Critical Care (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 20, 2023 Category: Consumer Health News Tags: Critical Care Viewpoint Source Type: news

Landiolol Does Not Reduce Organ Failure in Septic Shock Patients With Tachycardia
WEDNESDAY, Nov. 1, 2023 -- An infusion of landiolol does not reduce organ failure among patients with septic shock with tachycardia, according to a study published online Oct. 25 in the Journal of the American Medical Association to coincide with... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 1, 2023 Category: Pharmaceuticals Source Type: news

6 Stories Show the Human Toll of Poland ’ s Strict Abortion Laws
This project was supported by the Pulitzer Center [time-brightcove not-tgx=”true”] Krzysztof Sowinski has cried every day since his wife Marta, who was five months pregnant, died of sepsis in 2022; he believes doctors put Marta’s life in danger by not giving them the option to terminate the pregnancy while the fetus’ heart was still beating. Janusz Kucharski also lost his partner Justyna to sepsis in the fifth month of a pregnancy. She left behind two boys. It is likely, reproductive-rights advocates say, that these women would be alive if not for Poland’s increasingly restrictive abort...
Source: TIME: Health - October 13, 2023 Category: Consumer Health News Authors: Anna Pamula Tags: Uncategorized abortion Source Type: news

Vasopressin May Promote Lower Mortality in Septic Shock Vasopressin May Promote Lower Mortality in Septic Shock
Clinical trial data showed the value of vasopressin in reducing catecholamine doses.Medscape Medical News (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - August 1, 2023 Category: Intensive Care Tags: Pulmonary Medicine News Source Type: news

Report Alleges Narcan Revived Madonna, But Drug ’s Use Raises Questions
Because Narcan isn't typically used in instances of septic shock, the public is left with more questions than answers regarding its alleged use in Madonna ’s case. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - July 8, 2023 Category: Pharmaceuticals Authors: Joshua Cohen, Contributor Tags: Healthcare /healthcare Innovation /innovation business pharma & standard Source Type: news

Madonna Revived by Narcan? Doc Assaults Employee; Semaglutide Compounders Sued
(MedPage Today) -- Note that some links may require subscriptions. Madonna was reportedly found unresponsive and revived by a naloxone (Narcan) injection to combat acute septic shock before her ICU stay for a bacterial infection. But some experts... (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - July 7, 2023 Category: Endocrinology Source Type: news

Madonna Revived by Narcan; Doc Assaults Employee; Semaglutide Compounders Sued
(MedPage Today) -- Note that some links may require subscriptions. Madonna was reportedly found unresponsive and revived by a naloxone (Narcan) injection to combat acute septic shock before her ICU stay for a bacterial infection. (Radar Online... (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - July 7, 2023 Category: American Health Source Type: news

Hydrocortisone Does Not Reduce 90-Day Mortality in Septic Shock
WEDNESDAY, May 31, 2023 -- For patients with septic shock, intravenous hydrocortisone does not reduce 90-day mortality when compared with placebo, according to a study published online May 22 in NEJM Evidence. Romain Pirracchio, M.D., M.P.H., Ph.D.,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 31, 2023 Category: Pharmaceuticals Source Type: news

Steroid Hydrocortisone Alone May Not Cut Death Risk From Septic Shock: Study
TUESDAY, May 23, 2023 -- A new study finds that while hydrocortisone on its own may not prevent death from sepsis, it can improve survival when combined with other steroids while eliminating the need for vasopressor drugs. Vasopressor medications... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - May 23, 2023 Category: General Medicine Source Type: news

Early Adjunctive Methylene Blue in Septic Shock Patients Early Adjunctive Methylene Blue in Septic Shock Patients
Could methylene blue be considered as an early adjunctive therapy for ICU patients with septic shock?Critical Care (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - May 17, 2023 Category: Intensive Care Tags: Critical Care Journal Article Source Type: news

Association between timing and adequacy of antibiotics and adverse outcomes in patients with sepsis and septic shock: A multicentre retrospective cohort study.
Conclusions: In a large multicentre sample of patients with culture‐positive sepsis, inadequacy of antibiotics was associated with higher risk of in‐hospital mortality or ICU admission. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 9, 2023 Category: Consumer Health News Source Type: news

Septic shock: early rapid recognition and ongoing management
We describe best practice recommendations based on international guidelines, a review of primary literature, and a discussion of ongoing clinical trials and the nuances of therapeutic choices. Early diagnosis and aggressive intervention with timely antibiotics, fluid resuscitation and vasoactive medications are the most important interventions in to improve outcomes. The implementation of protocols, resource-adjusted sepsis bundles and advanced technologies will impact on reducing sepsis mortality. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 9, 2023 Category: Consumer Health News Source Type: news

Thiamine pharmaconutrition in sepsis: Monotherapy, combined therapy, or neither? Current evidence on safety and efficacy
Sepsis is a life-threatening condition characterized by multiorgan dysfunction due to an exaggerated host response to infection associated with a homeostatic failure. In sepsis, different interventions, aimed at improving clinical outcomes, have been tested over the past decades. Among these most recent strategies, intravenous high-dose micronutrients (vitamins and/or trace elements) have been investigated. According to current knowledge, sepsis is characterized by low thiamine levels, which are associated with illness severity, hyperlactatemia, and poor clinical outcomes. However, caution is needed about the clinical inte...
Source: Current Awareness Service for Health (CASH) - May 9, 2023 Category: Consumer Health News Source Type: news

Comparative Effectiveness of Fludrocortisone and Hydrocortisone vs Hydrocortisone Alone Among Patients With Septic Shock
Question: What is the comparative effectiveness of fludrocortisone added to hydrocortisone vs hydrocortisone alone among patients with septic shock? Findings: In this multicenter cohort study among 88 275 patients with septic shock receiving norepinephrine who initiated hydrocortisone treatment, the addition of fludrocortisone to hydrocortisone was associated with a 3.7% lower adjusted absolute risk difference in the primary composite outcome of mortality or discharge to hospice compared with initiation of hydrocortisone alone. Meaning: Among patients with septic shock receiving norepinephrine who initiated hydrocortisone ...
Source: Current Awareness Service for Health (CASH) - April 14, 2023 Category: Consumer Health News Source Type: news

Hydrocortisone Plus Fludrocortisone Superior for Septic Shock
THURSDAY, April 13, 2023 -- Among adult patients with septic shock who begin hydrocortisone treatment, the addition of fludrocortisone is superior to hydrocortisone alone, according to a study published online March 27 in JAMA Internal... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 13, 2023 Category: Pharmaceuticals Source Type: news