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Ceftriaxone (Ceftriaxone Sodium and Dextrose Injection ) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - October 18, 2017 Category: Drugs & Pharmacology Source Type: news

Azithromycin and Ceftriaxone Resistance in N gonorrhoeae Azithromycin and Ceftriaxone Resistance in N gonorrhoeae
Azithromycin and ceftriaxone are the recommended treatment options for Neisseria gonorrhoeae, but treatment failures have been reported.Emerging Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 17, 2017 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

Gonorrhea Becoming More Difficult To Treat With Antibiotics
CBS Local — Gonorrhea is becoming more difficult to treat with antibiotics and for some patients it’s become impossible, the World Health Organization (WHO) said. Three forms of bacteria known as “superbugs” that cannot be killed by the best available gonorrhea medicine have been detected in Spain, France and Japan, according to the WHO. “The bacteria that cause gonorrhea are particularly smart. Every time we use a new class of antibiotics to treat the infection, the bacteria evolve to resist them,” said Teodora Wi, a human reproduction specialist for the WHO, in a press release. Analysi...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - July 7, 2017 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Antibiotics Dan Corey Medicine STDs Source Type: news

Amoxicillin and Ceftriaxone for Maternal Syphilis Amoxicillin and Ceftriaxone for Maternal Syphilis
When penicillin is not available, should amoxicillin and ceftriaxone be considered as treatment options for maternal syphilis?Emerging Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 3, 2017 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

Rapid Assay Revives Ciprofloxacin Use for Gonorrhea Rapid Assay Revives Ciprofloxacin Use for Gonorrhea
A pharmacogenomics approach identified gonorrhea infections susceptible to ciprofloxacin and allowed physicians to reserve ceftriaxone for resistant cases.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 2, 2017 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Scientists develop test to identify best treatment for gonorrhea
FINDINGSResearchers from UCLA have developed a laboratory test that helps physicians determine which people with gonorrhea may be more treatable with an antibiotic that has not been recommended since 2007 because of concerns that the resistance to the drug was growing.BACKGROUNDGonorrhea has developed increasing resistance to all current antibiotics. Due to the spread of multi-drug resistant gonorrhea, health authorities have declared it one of the top-three urgent threats to public health.Ciprofloxacin was used to combat the sexually transmitted infection until 2007, when the Centers for Disease Control and Prevention sto...
Source: UCLA Newsroom: Health Sciences - May 23, 2017 Category: Universities & Medical Training Source Type: news

Nigeria: PSN Donates Meningitis Drugs to Sokoto
[Daily Trust] Lagos -The national body of Pharmaceutical Society of Nigeria (PSN) has donated drugs (Inj. Ceftriaxone) to the Sokoto state government to help curb the scourge of meningitis epidemic in the state. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - May 15, 2017 Category: African Health Source Type: news

Rocephin (Ceftriaxone) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - April 11, 2017 Category: Drugs & Pharmacology Source Type: news

Tanzania: Powercef - Medicine Widely Used and 'Abused' in Tanzania
[Citizen] There is this popular and widely used antibiotic in Tanzania, known as Powercef whose generic name is Ceftriaxone. It's being prescribed 'irrationally' in the country. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 5, 2017 Category: African Health Source Type: news

Incurable: Gonorrhea outbreak in Hawaii showing increased antibiotic resistance
(NaturalNews) At least seven patients from Hawaii are suffering from what health experts fear may eventually become an incurable outbreak of gonorrhea. The sexually-transmitted disease (STD) is typically treatable with antibiotic drugs like ceftriaxone and azithromycin, but growing... (Source: NaturalNews.com)
Source: NaturalNews.com - October 4, 2016 Category: Consumer Health News Source Type: news

Second Chance on Bladder US
“If you are given a second chance in life, don’t blow it,” you advise your eager resident. It has been an overwhelmingly busy day in the department. Interspersed between the motor vehicle collisions, hypoxic and hypotensive CHF exacerbations, and patients with florid sepsis, your team is trying to see and help all of the ankle pains, throat pains, and dysuria that have also walked through the waiting room doors. The neighborhood clinics are completely overbooked, and your department has been dealing with the overflow all week. Your resident has three charts in her hand and has just finished presenting the...
Source: EPMonthly.com - September 27, 2016 Category: Emergency Medicine Authors: Logan Plaster Tags: Uncategorized Source Type: news

Drug-Resistant Gonorrhea Strain In Hawaii A First For U.S.
A drug-resistant cluster of gonorrhea infections in Hawaii have health officials worried that the sexually transmitted disease could soon prove untreatable. The Centers for Disease Control and Prevention announced this week that an antibiotic-resistant strain was discovered earlier this year in seven patients in Honolulu. All the individuals ― six men and one woman ― were successfully treated using the CDC-recommended two-drug combination of ceftriaxone and azithromycin. Laboratory tests, however, showed the strain had “decreased susceptibility to ceftriaxone and very high-level resistance to azithromycin,”...
Source: Science - The Huffington Post - September 23, 2016 Category: Science Source Type: news

Drug-Resistant Gonorrhea Strain In Hawaii A First For U.S.
A drug-resistant cluster of gonorrhea infections in Hawaii have health officials worried that the sexually transmitted disease could soon prove untreatable. The Centers for Disease Control and Prevention announced this week that an antibiotic-resistant strain was discovered earlier this year in seven patients in Honolulu. All the individuals ― six men and one woman ― were successfully treated using the CDC-recommended two-drug combination of ceftriaxone and azithromycin. Laboratory tests, however, showed the strain had “decreased susceptibility to ceftriaxone and very high-level resistance to azithromycin,”...
Source: Healthy Living - The Huffington Post - September 23, 2016 Category: Consumer Health News Source Type: news

CDC Finds First Cluster of Highly Resistant Gonorrhea in US CDC Finds First Cluster of Highly Resistant Gonorrhea in US
The cases showed high-level resistance to azithromycin and reduced susceptibility to ceftriaxone, a'troubling'sign, one official said.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 22, 2016 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Second Chance on Bladder US
“If you are given a second chance in life, don’t blow it,” you advise your eager resident. It has been an overwhelmingly busy day in the department. Interspersed between the motor vehicle collisions, hypoxic and hypotensive CHF exacerbations, and patients with florid sepsis, your team is trying to see and help all of the ankle pains, throat pains, and dysuria that have also walked through the waiting room doors. The neighborhood clinics are completely overbooked, and your department has been dealing with the overflow all week. Your resident has three charts in her hand and has just finished presenting the...
Source: EPMonthly.com - September 19, 2016 Category: Emergency Medicine Authors: Logan Plaster Tags: Uncategorized Source Type: news

Antibiotic-Resistant Gonorrhea Is A Looming Threat
The Centers for Disease Control and Prevention reported Thursday that Neisseria gonorrhoeae ― that is, the bacteria that causes gonorrhea ― could be developing resistance to our last-line antibiotics that treat it. The CDC’s current gold standard treatment for gonorrhea is a combination of two drugs, azithromycin and ceftriaxone, to ensure that if one drug doesn’t kill the bacteria, the other will finish the job. Now, a rise in antibiotic resistance among these two bacteria since 2014 has experts worried. “History has taught us that this bacteria has the ability to develop resistance to...
Source: Science - The Huffington Post - July 19, 2016 Category: Science Source Type: news

Antibiotic-Resistant N. gonorrhoeae May Be Increasing (FREE)
By the Editors Gonorrhea infections in the U.S. may be growing more resistant to the only recommended treatment, ceftriaxone plus … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - July 17, 2016 Category: Primary Care Source Type: news

This month’s toughest USMLE Step 2 question to master
Getting ready for the United States Medical Licensing Examination® (USMLE®) Step 2 is no easy feat, but we’re sharing expert insights to help give you a leg up. Take a look at the exclusive scoop on this month’s most-missed USMLE Step 2 test prep question. Think you have what it takes to rise above your peers? Test your USMLE knowledge, and view an expert video explanation of the answer from Kaplan Medical. Once you’ve got this question under your belt, be sure to test your knowledge with other posts in this series. Ready. Set. Go. This month’s question that stumped most students:...
Source: AMA Wire - June 28, 2016 Category: Journals (General) Authors: Troy Parks Source Type: news

This month ’s toughest USMLE Step 2 question to master
Getting ready for the United States Medical Licensing Examination ® (USMLE®) Step 2 is no easy feat, but we’re sharing expert insights to help give you a leg up. Take a look at the exclusive scoop on this month’s most-missed USMLE Step 2 test prep question. Think you have what it takes to rise above your peers? Test your USMLE knowledge, and view an expert v ideo explanation of the answer from Kaplan Medical. Once you ’ve got this question under your belt, be sure to test your knowledge with  other posts in this series . Ready. Set. Go. This month ’s question that stumped most st...
Source: AMA Wire - June 28, 2016 Category: Journals (General) Authors: Troy Parks Source Type: news

Warning issued over alarming rise in 'super-gonorrhoea' cases
"Doctors have expressed 'huge concern' that super-gonorrhoea has spread widely across England," BBC News reports. Public Health England issued the warning about the rise of a strain of gonorrhoea that has developed resistance to a widely used antibiotic.  What is gonorrhoea? Gonorrhoea is a sexually transmitted infection (STI) caused by bacteria called Neisseria gonorrhoeae or gonococcus. It used to be known as "the clap". The bacteria are mainly found in discharge from the penis and vaginal fluid. It is easily passed between people through: unprotected vaginal, oral or anal sex sh...
Source: NHS News Feed - April 18, 2016 Category: Consumer Health News Tags: Medical practice Lifestyle/exercise Medication QA articles Source Type: news

At What Age Does the Risk of Infant Listeria Infection Decrease?
Discussion Neonatal bacterial infections are commonly caused by Group B Streptococcus, enteric gram-negative organisms such as Escherichia coli, coagulase negative Staphylococcus, Listeria monocytogenes and Haemophilus influenza. Infections are usually because of transplacental infection or ascending infection from the mother’s genitourinary tract. Empiric treatment for suspected sepsis for neonates is usually combined IV aminoglycoside and expanded-spectrum penicillin antibiotic therapy in the US and Canada and this combination specifically covers for Listeria. Listeria monocytogenes was first discovered in 1927 an...
Source: PediatricEducation.org - January 25, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Emerging Extended-Spectrum Cephalosporin Resistance in
Over the last several decades, Neisseria gonorrhoeae has sequentially developed resistance to the agents recommended by the CDC and the Public Health Service for the treatment of gonorrhea. During the 1970s and through the 1990s, penicillin, tetracyclines, and the fluoroquinolones were recommended and subsequently removed as the therapy of choice for gonorrhea, leaving intramuscular ceftriaxone and the oral cephalosporin cefixime as the sole agents recommended for treatment of gonorrhea in 2010. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - January 12, 2016 Category: Microbiology Authors: William M. Janda Source Type: news

What Are Risk Factors for Cholelithiasis?
Discussion Bile is produced by the liver to aid absorption of fat soluble vitamins and lipids from the gastrointestinal tract and to transport bilirubin, cholesterol and other substances to the gastrointestinal tract. Bile is the main form of cholesterol excretion. Gallstones or cholelithiasis form when the balance of substances within the hepatobiliary tract favors supersaturation with crystal formation and gallstone formation. It is a dynamic state of affairs as gallstones can form and also have a high rate of resorption of up to 50%. Gallstones 3 mm are called gallstones. Gallstones, while not as common as adult popula...
Source: PediatricEducation.org - January 4, 2016 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Resistant gonorrhea rates high in China, raise concerns in U.S.
SAN DIEGO – Experts in the field of Neisseria gonorrhoeae antimicrobial resistance are warily watching developments in China, where rates of nonsusceptibility to ceftriaxone are reportedly shooting through the roof. In the United States at present, gonococcal resistance to ceftriaxone is... (Source: Skin and Allergy News)
Source: Skin and Allergy News - November 15, 2015 Category: Dermatology Source Type: news

2014 saw spike in antibiotic-resistant gonorrhea
Enhanced gonorrhea susceptibility to third-generation cephalosporin-class antibiotic agents such as injectable ceftriaxone and oral cefixime may have been temporary, according to a retrospective analysis published in the Nov. 3 issue of JAMA. The findings of
Source: Skin and Allergy News - November 3, 2015 Category: Dermatology Source Type: news

ACOG Advocates Dual Therapy for Gonococcal InfectionsACOG Advocates Dual Therapy for Gonococcal Infections
Ceftriaxone plus azithromycin is the recommended first-line regimen in the face of antimicrobial resistance. Medscape Medical News (Source: Medscape PublicHealth Headlines)
Source: Medscape PublicHealth Headlines - October 22, 2015 Category: Primary Care Tags: Ob/Gyn & Women ' s Health News Source Type: news

Class I Medical Device Recall: Siemens Healthcare Diagnostics, Rapid Gram Negative Combo Panels - May Produce Incorrect Results
Reason for Recall: Incorrect test results may occur for the following antibiotics: Aztreonam, Cefotaxime, Ceftazidime, and Ceftriaxone. The test may report certain bacteria as sensitive to one of these antibiotics when the bacteria are actually resistant. (Source: Food and Drug Adminstration (FDA): CDRHNew)
Source: Food and Drug Adminstration (FDA): CDRHNew - December 1, 2014 Category: Medical Equipment Source Type: news

Make the Diagnosis: A Middle-Aged Woman with Sudden Leg Weakness
(MedPage Today) -- Case Study: A fifty-six-year-old woman presented to the emergency department with a sudden onset of dyspnea, stupor, and weakness of both lower extremities. She had been in good health until two weeks previously, during which she had undergone nonoperative treatment for lower back pain. She received ceftriaxone for a fever that developed two days before arrival in the emergency room. She had diabetes mellitus and high blood pressure, but no specific event or invasive procedure triggered the onset of the symptoms. The patients temperature was 36.5°C, and she had back tenderness and marked global weak...
Source: MedPage Today Endocrinology - October 24, 2014 Category: Endocrinology Source Type: news

Determination of Antimicrobial Resistance in Salmonella spp.
Infections with Salmonella are an important public health problem worldwide. Salmonella are one of the most common causes of food-borne illness in humans. There are many types of Salmonella but they can be divided into two broad categories: those that cause typhoid and those that do not. The typhoidal Salmonella (TS), such as S. enterica subsp. enterica serovars Typhi and S. Paratyphi only colonize humans and are usually acquired by the consumption of food or water contaminated with human fecal material. The much broader group of non-typhoidal Salmonella (NTS) usually results from improperly handled food that has been cont...
Source: Springer protocols feed by Infectious Diseases - September 25, 2014 Category: Infectious Diseases Source Type: news

Ceftaroline Superior in Community-Acquired Pneumonia in AsiaCeftaroline Superior in Community-Acquired Pneumonia in Asia
Ceftaroline fosamil is superior to ceftriaxone for community-acquired pneumonia, a phase 3 trial of Asian patients shows. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 19, 2014 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

Two Regimens for Respiratory and Urinary Tract InfectionsTwo Regimens for Respiratory and Urinary Tract Infections
Is ceftriaxone/sulbactam as effective and well-tolerated as cefoperazone/sulbactam for the treatment of urinary tract and respiratory infections caused by resistant bacteria? Annals of Clinical Microbiology and Antimicrobials (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 25, 2014 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

Ceftriaxone Linked to Renal Failure in ChildrenCeftriaxone Linked to Renal Failure in Children
A retrospective study has linked therapeutic doses of ceftriaxone with renal failure in kids and has suggested that early treatment can be effective in recovery. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 24, 2014 Category: Consumer Health News Tags: Pediatrics News Source Type: news

The Threat of Antibiotic Resistance - CDC video
This animated video highlights the key points and graphics of the CDC report Antibiotic Threats in the United States, 2013.For example, gonorrhea is getting harder to treat and antibiotic resistance is pushing Neisseria gonorrhoeae toward superbug status. The current drugs of choice, ceftriaxone and cefixime, are still very effective but there are signs that resistance, particularly to cefixime, is emerging and soon these drugs may not be a good choice.Only one remaining class of antibiotics is recommended for the treatment of gonorrhea - cephalosporins. Historically, gonorrhea has progressively developed resistance to the...
Source: Clinical Cases and Images - January 31, 2014 Category: Journals (General) Tags: CDC Infectious Diseases Source Type: news

Comparing penicillin and 'big gun' antibiotics for treating less severe childhood pneumonia
Children hospitalized for pneumonia have similar outcomes, including length of stay and costs, regardless of whether they are treated with "big gun" antibiotics such as ceftriaxone or cefotaxime or more narrowly focused antibiotics such as ampicillin or penicillin, according to a Vanderbilt study published in Pediatrics.Study authors said the findings are important because pneumonia is one of the most common reasons for hospitalization among U.S. children and because broad-spectrum antibiotics are frequently over-prescribed, leading to antibiotic resistance. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 12, 2013 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Penicillin equally effective as 'big gun' antibiotics for treating less severe childhood pneumonia
(Vanderbilt University Medical Center) Children hospitalized for pneumonia have similar outcomes, including length of stay and costs, regardless of whether they are treated with "big gun" antibiotics such as ceftriaxone or cefotaxime or more narrowly focused antibiotics such as ampicillin or penicillin, according to a Vanderbilt study published in Pediatrics. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 9, 2013 Category: Global & Universal Source Type: news

How Common Are Post-Dural Puncture Headaches in Children?
Discussion Post-dural puncture headache or spinal headache as they are often called, are headaches that occur within 7 days of a lumbar puncture and remit within 14 days of the lumbar puncture. They begin or worsen within 15 minutes of being in an upright position and improve or stop within 30 minutes of lying down. The headaches are described as a throbbing, dull and severe pain worse mainly in the occipital area, but can occur with radiation to the eyes, forehead or neck. Nausea, emesis, stiff neck, and visual or auditory changes may also occur. Most spinal headaches occur within 1-2 days of the lumbar puncture and spont...
Source: PediatricEducation.org - October 14, 2013 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news

How Common Are Post-Dural Puncture Headaches in Children?
Discussion Post-dural puncture headache or spinal headache as they are often called, are headaches that occur within 7 days of a lumbar puncture and remit within 14 days of the lumbar puncture. They begin or worsen within 15 minutes of being in an upright position and improve or stop within 30 minutes of lying down. The headaches are described as a throbbing, dull and severe pain worse mainly in the occipital area, but can occur with radiation to the eyes, forehead or neck. Nausea, emesis, stiff neck, and visual or auditory changes may also occur. Most spinal headaches occur within 1-2 days of the lumbar puncture and spont...
Source: PediatricEducation.org - October 14, 2013 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Last-Line Antibiotics Increasingly Ineffective Against Gonorrhoea But Prescribing Changes Could Help Delay Spread Of Untreatable Disease, UK
The last remaining antibiotics used to treat gonorrhoea (cefixime and ceftriaxone) in England and Wales are becoming less effective. But recent changes in prescribing practice, based on new recommendations that challenge previous public health thinking, seem to have delayed or reversed this trend, and may help to delay the growing threat of multi-drug resistant gonorrhoea, suggests new research published Online First in The Lancet Infectious Diseases. "Fears continue that the current cephalosporins will become ineffective... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 14, 2013 Category: Consumer Health News Tags: MRSA / Drug Resistance Source Type: news

Could Renal Abscess Be a Complication of Pyelonephritis in this Patient?
Discussion Urinary tract infections (UTI) are common. By the age of 7 years up to 8% of girls and 2% of boys have had a UTI. The current American Academy of Pediatrics criteria for a UTI diagnosis includes presence of pyruria (determined by microscopy) or leucocyte esterase (on dipstick) AND a culture-positive urine of 100,000 colony-forming units on a voided specimen. Because of possible contamination, bagged specimens are not acceptable. Clinical pyelonephritis (ie febrile UTI) is a fairly common problem in the pediatric population. Learning Point Renal abscesses are uncommon with the exact incidence unknown and are defi...
Source: PediatricEducation.org - January 14, 2013 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news