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Total 493674 results found since Jan 2013.

Impact of preoperative spinal injections within 30 days of lumbar decompression on surgical outcomes: a matched institutional study
CONCLUSIONS: Lumbar decompression within 1 month of preoperative spinal injection was associated with higher risks of readmission and postoperative complications, including CSF leak. However, with the exception of CSF leak, these risks were no longer observed when spinal injection occurred 1-3 months prior to lumbar decompression.PMID:37728375 | DOI:10.3171/2023.6.SPINE23356
Source: Journal of Neurosurgery.Spine - September 20, 2023 Category: Neurosurgery Authors: Patrick Flanigan Karim R Nathani Michael Martini Giorgos D Michalopoulos Selby Chen Maziyar Kalani Mohamad Bydon Source Type: research

Relationship between 4-month functional brain network topology and 24-month neurodevelopmental outcome in children with congenital heart disease
Eur J Paediatr Neurol. 2023 Sep 11;47:47-59. doi: 10.1016/j.ejpn.2023.09.005. Online ahead of print.ABSTRACTSurvivors of complex forms of congenital heart disease (CHD)∗ are at high risk of neurodevelopmental disabilities. Neuroimaging studies have pointed to brain anomalies and immature networks in infants with CHD, yet less is known about their functional network topology and associations with neurodevelopment. To characterize the functional network topology in 4-month-old infants with repaired CHD, we compared graph theory metrics measured using resting-state functional near-infrared spectroscopy (rs-fNIRS) between in...
Source: European Journal of Paediatric Neurology - September 20, 2023 Category: Neurology Authors: Sarah Provost Sol ène Fourdain Phetsamone Vannasing Julie Tremblay Kassandra Roger Yalina Garc ía-Puente Am élie Doussau Marie-Claude Vinay Zorina Von Siebenthal Natacha Paquette Nancy Poirier Anne Gallagher Source Type: research

The self-regulating on cohesion properties of calcium phosphate/ calcium sulfate bone cement improved by citric acid/sodium alginate
Colloids Surf B Biointerfaces. 2023 Sep 16;231:113548. doi: 10.1016/j.colsurfb.2023.113548. Online ahead of print.ABSTRACTCalcium phosphate cement (CPC) has attracted extensive interest from surgeons and materials scientists. However, the collapsibility of calcium phosphate cement limits its clinical application. In this work, a gel network of SA-CA formed by the reaction of citric acid (CA) and sodium alginate (SA) was introduced into the α-TCP/α-CSH composite. Furthermore, a high proportion of α-CSH provided more calcium sources for the system to combine with SA forming a gel network to improve the cohesion property o...
Source: Colloids and Surfaces - September 20, 2023 Category: Biotechnology Authors: Hongyun Zhao Junjia Kang Xiaojie Lian Yaping Song Di Wang Ruoyao Xu Liqin Zhao Di Huang Baolong Niu Source Type: research

Beyond the Advanced Therapies Skills Training Network: An Instrumental Case Study of Life Sciences Skills Development for Biomedical Science Graduates in Scotland
Br J Biomed Sci. 2023 Sep 4;80:11654. doi: 10.3389/bjbs.2023.11654. eCollection 2023.ABSTRACTBiomedical sciences graduates are employed in a variety of different settings and form a significant part of the Life Sciences sector workforce in Scotland. Their degrees should equip them with the skills and knowledge to not only enter the workplace, but be adaptable in an environment that will inevitably change over the course of their careers. Industry and student feedback continue to identify perceived skills gaps, necessitating regular government-backed upskilling initiatives together with industry concerns about graduate read...
Source: British Journal of Biomedical Science - September 20, 2023 Category: Laboratory Medicine Authors: Claire L P Garden Source Type: research

E2F1-EP300 co-activator complex potentiates immune escape in nasopharyngeal carcinoma through the mediation of MELK
In this study, we investigated the role of MELK during immune escape in NPC.METHODS: Differentially expressed genes were filtered using GEO datasets and PPI network analysis. NPC cell colony formation and motility were examined, and the impact of CD8⁺ T cells on NPC cells was evaluated. A xenograft model was constructed to detect the growth of tumor cells and the T-cell phenotype of tumor infiltration. ChIP-qPCR and dual-luciferase assays were used to verify the transcriptional regulation of MELK by EP300/E2F1.FINDINGS: MELK was overexpressed in NPC, and sh-MELK suppressed the clonogenic ability, migration, and invasion ...
Source: Histology and Histopathology - September 20, 2023 Category: Cytology Authors: Qiang Wang Qi Yu Yueyang Liu Source Type: research

Focal Lesion in the Intraparietal Sulcus: A Case for Network-Dependent Release Hallucinations
J Neuropsychiatry Clin Neurosci. 2023 Sep 20:appineuropsych20220145. doi: 10.1176/appi.neuropsych.20220145. Online ahead of print.NO ABSTRACTPMID:37727058 | DOI:10.1176/appi.neuropsych.20220145
Source: Journal of Neuropsychiatry and Clinical Neurosciences - September 20, 2023 Category: Psychiatry Authors: Yidi Wang Andrew R Pines Joseph Y Yoon Summer B Frandsen Edison K Miyawaki Shan H Siddiqi Source Type: research

Ferroptosis and WDFY4 as novel targets for immunotherapy of lung adenocarcinoma
CONCLUSIONS: The results indicate that promoting infiltration and activation of B cell populations could improve the long-term survival of LUAD patients, thereby offering a potential novel immunotherapeutic approach for LUAD. Besides, the promotion of cancer cell ferroptosis and upregulation of WDFY4 expression have been shown to induce the infiltration and activation of B cell populations. Furthermore, the overexpression of WDFY4 can significantly inhibit the growth of lung adenocarcinoma in vitro and in vivo, highlighting its potential as a target for immunotherapy in LUAD.PMID:37728413 | DOI:10.18632/aging.205042
Source: Aging - September 20, 2023 Category: Biomedical Science Authors: Ling Huang Lifan Zhong Ruxin Cheng Limei Chang Mingyan Qin Huaping Liang Zhongkai Liao Source Type: research

Should we be screening for COPD? - looking through the lens of lung cancer screening
Expert Rev Respir Med. 2023 Sep 20. doi: 10.1080/17476348.2023.2259800. Online ahead of print.ABSTRACTINTRODUCTION: In May 2022, the US Preventive Services Task Force published their recommendation against screening for chronic obstructive pulmonary disease (COPD) in asymptomatic adults. However, we argue the routine use of spirometry in both asymptomatic and symptomatic high-risk smokers has utility.AREAS COVERED: We provide published and unpublished observations from a secondary analyses of the American College of Radiology Imaging Network(ACRIN), arm of the National Lung Screening Trial, including 18,643 high-risk curre...
Source: Expert Review of Respiratory Medicine - September 20, 2023 Category: Respiratory Medicine Authors: Robert P Young Raewyn J Scott Source Type: research

Apical polarity and actomyosin dynamics control Kibra subcellular localization and function in Drosophila Hippo signaling
This study provides a mechanistic understanding of the relationship between the Hippo pathway, polarity, and actomyosin cytoskeleton, and it offers novel insights into how fundamental features of epithelial tissue architecture can serve as inputs into signaling cascades that control tissue growth, patterning, and morphogenesis.PMID:37729921 | DOI:10.1016/j.devcel.2023.08.029
Source: Developmental Cell - September 20, 2023 Category: Cytology Authors: Sherzod A Tokamov Nicki Nouri Ashley Rich Stephan Buiter Michael Glotzer Richard G Fehon Source Type: research

Research Authorship
Hi all, So obviously it's important for medical students to have their names on research publications before applying for residency, and even better if they can be first author on any of them. My question then is as such— I am currently managing a bunch of research projects with other medical students, independent of a lab. I am acting as the primary investigator, and most of my work is conception of the idea, statistics if needed, and collecting the results. I then guide students with less... Read more
Source: Student Doctor Network - September 20, 2023 Category: Universities & Medical Training Authors: mshalom13 Tags: Medical Students (MD) Source Type: forums

Clinical rotation application in NY
As a foreign medical student, this is my first time (and i believe it'd gonna be my last time) trying to apply clinical rotation in US...however, i found that the appplication date was kinda confusing...according to VSLO, the application deadline was stated as 60 days before admission, however, the official webpage of the program was written as 6 months before the first elective date, which i had already missed.......i dun know whether i should give it a shot or i should just give up. the... Read more
Source: Student Doctor Network - September 20, 2023 Category: Universities & Medical Training Authors: watercyn Tags: General International Discussion Source Type: forums

Ben Armstrong Raises Over $120K In Bitcoin, Ethereum, Cardano Donations Within Hours For Legal Fight Against Hit Network
Crypto influencer Ben Armstrong on Tuesday alleged that Hit Network, the organization he was associated with, has not only taken away his financial resources but has also left him unable to fight back. Armstrong took to X to appeal to his followers for assistance in funding his legal campaign to…#benarmstrong #hitnetwork #bitboycrypto #ethereumethusd #bitcoinbtcusd #cardanoadausd #benzingasfutureof #floatingpalace #jamesbond #justinwilliams
Source: Reuters: Health - September 20, 2023 Category: Consumer Health News Source Type: news

BitBoy Raises $50000 in 5 Hours: Crypto Community ‘Pissed’
Prominent YouTuber Ben Armstrong, more commonly known as “Bitboy” previously, recently filed a lawsuit against Hit Network CEO Timothy “TJ” Shedd Jr. and father Timothy Shedd Sr. for removing him from the media company he created in 2018. The filing alleged that the Shedds “began conspiring to…#benarmstrong #bitboy #hitnetwork #timothytjsheddjr #timothysheddsr #youtuber #bitboycrypto #ethaddress #benarmstrongsx #readbinance
Source: Reuters: Health - September 20, 2023 Category: Consumer Health News Source Type: news

Horizen and Pyth Network team up to amplify decentralized oracle services for EON
Horizen Labs announced a partnership with Pyth Network, a specialized Oracle solution, on September 19 to deliver decentralized Oracle services for EON, Horizen’s EVM-compatible smart contracting platform. The proposed partnership aims to provide precise and reliable market data on the blockchain…#horizenlabs #pythnetwork #oracle #eon #horizen #nft #pythnetworks #defi #robviglione #partneringwith
Source: Reuters: Health - September 20, 2023 Category: Consumer Health News Source Type: news

Telefonica may seek damages in event of Huawei curbs in Germany
Telefonica Deutschland on Wednesday said it would consider seeking damages from the German government as well as legal action if Berlin imposed restrictions on using China's Huawei that meant retrospective changes to its network. In a statement to Reuters, Telefonica Deutschland said it was in…#berlin #huawei #zte
Source: Reuters: Health - September 20, 2023 Category: Consumer Health News Source Type: news