Apical polarity and actomyosin dynamics control Kibra subcellular localization and function in Drosophila Hippo signaling

This study provides a mechanistic understanding of the relationship between the Hippo pathway, polarity, and actomyosin cytoskeleton, and it offers novel insights into how fundamental features of epithelial tissue architecture can serve as inputs into signaling cascades that control tissue growth, patterning, and morphogenesis.PMID:37729921 | DOI:10.1016/j.devcel.2023.08.029

Source: Developmental Cell - September 20, 2023 Category: Cytology Authors: Sherzod A Tokamov Nicki Nouri Ashley Rich Stephan Buiter Michael Glotzer Richard G Fehon Source Type: research