Effects of ondansetron exposure during ICU stay on outcomes of critically ill patients with sepsis: a cohort study
ConclusionOND exposure might be associated with lower in-hospital, 28-day, and 90-day mortality rates in critically ill patients with sepsis. This study indicated that OND might help improve the prognosis of patients with sepsis. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - December 21, 2023 Category: Microbiology Source Type: research
Anti-inflammatory and antinociceptive effects of sitagliptin in animal models and possible mechanisms involved in the antinociceptive activity
CONCLUSIONS: : NO/cGMP/KATP, 5HT3 and D2 pathways play an important role in the antinociceptive effect of sitagliptin. Additionally significant anti-inflammatory effects observed in the carrageenan test might contribute in reduction of pain response in the second phase of the formalin test.PMID:38123184 | DOI:10.3344/kjp.23262 (Source: Korean Journal of Pain)
Source: Korean Journal of Pain - December 20, 2023 Category: Anesthesiology Authors: Valiollah Hajhashemi Hossein Sadeghi Fatemeh Karimi Madab Source Type: research
Associations between ondansetron and the incidence of postoperative nausea and vomiting and food intake in Japanese female undergoing laparoscopic gynecological surgery: a retrospective study
ConclusionOndansetron administration during surgery was significantly associated with decreased PONV risk but was not associated with food intake the day after surgery. (Source: Journal of Anesthesia)
Source: Journal of Anesthesia - December 18, 2023 Category: Anesthesiology Source Type: research
Ondansetron for Spinal Opioid-Induced Pruritis
Anesth Analg. 2024 Jan 1;138(1):69. doi: 10.1213/ANE.0000000000006843. Epub 2023 Dec 15.NO ABSTRACTPMID:38100800 | DOI:10.1213/ANE.0000000000006843 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - December 15, 2023 Category: Anesthesiology Authors: Naveen Nathan Source Type: research
Ondansetron for Spinal Opioid-Induced Pruritis
Anesth Analg. 2024 Jan 1;138(1):69. doi: 10.1213/ANE.0000000000006843. Epub 2023 Dec 15.NO ABSTRACTPMID:38100800 | DOI:10.1213/ANE.0000000000006843 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - December 15, 2023 Category: Anesthesiology Authors: Naveen Nathan Source Type: research
Ondansetron for Spinal Opioid-Induced Pruritis
Anesth Analg. 2024 Jan 1;138(1):69. doi: 10.1213/ANE.0000000000006843. Epub 2023 Dec 15.NO ABSTRACTPMID:38100800 | DOI:10.1213/ANE.0000000000006843 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - December 15, 2023 Category: Anesthesiology Authors: Naveen Nathan Source Type: research
Assessing the impact of aprepitant and ondansetron on postoperative nausea and vomiting in orthognathic surgeries: a randomized controlled trial
Postoperative nausea and vomiting (PONV) is a common side effect associated with general anesthesia. Both ondansetron and aprepitant been effectively used to prevent PONV. However, there is a disagreement of o... (Source: BMC Anesthesiology)
Source: BMC Anesthesiology - December 13, 2023 Category: Anesthesiology Authors: Mostafa Alam, Alireza Shakeri, Ardeshir Khorsand, Karim Nasseri and Sadaf Nasseri Tags: Research Source Type: research
The Incidence of Torsades de Pointes With Perioperative Triple Antiemetic Administration
CONCLUSIONS AND RELEVANCE: No episodes of TdP were identified in patients receiving triple antiemetic therapy perioperatively, though the cause of death in 1 patient could not be determined. This suggest that low-dose triple antiemetic therapy is low risk for the development of TdP.PMID:38053391 | DOI:10.1177/10600280231215786 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - December 6, 2023 Category: Drugs & Pharmacology Authors: Gregory A Nuttall Alyssa M Reed Khue D Pham Louis Lance J Oyen Samuel P Marsland Michael J Ackerman Source Type: research
The Incidence of Torsades de Pointes With Perioperative Triple Antiemetic Administration
CONCLUSIONS AND RELEVANCE: No episodes of TdP were identified in patients receiving triple antiemetic therapy perioperatively, though the cause of death in 1 patient could not be determined. This suggest that low-dose triple antiemetic therapy is low risk for the development of TdP.PMID:38053391 | DOI:10.1177/10600280231215786 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - December 6, 2023 Category: Drugs & Pharmacology Authors: Gregory A Nuttall Alyssa M Reed Khue D Pham Louis Lance J Oyen Samuel P Marsland Michael J Ackerman Source Type: research
The Incidence of Torsades de Pointes With Perioperative Triple Antiemetic Administration
CONCLUSIONS AND RELEVANCE: No episodes of TdP were identified in patients receiving triple antiemetic therapy perioperatively, though the cause of death in 1 patient could not be determined. This suggest that low-dose triple antiemetic therapy is low risk for the development of TdP.PMID:38053391 | DOI:10.1177/10600280231215786 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - December 6, 2023 Category: Drugs & Pharmacology Authors: Gregory A Nuttall Alyssa M Reed Khue D Pham Louis Lance J Oyen Samuel P Marsland Michael J Ackerman Source Type: research
The Incidence of Torsades de Pointes With Perioperative Triple Antiemetic Administration
CONCLUSIONS AND RELEVANCE: No episodes of TdP were identified in patients receiving triple antiemetic therapy perioperatively, though the cause of death in 1 patient could not be determined. This suggest that low-dose triple antiemetic therapy is low risk for the development of TdP.PMID:38053391 | DOI:10.1177/10600280231215786 (Source: The Annals of Pharmacotherapy)
Source: The Annals of Pharmacotherapy - December 6, 2023 Category: Drugs & Pharmacology Authors: Gregory A Nuttall Alyssa M Reed Khue D Pham Louis Lance J Oyen Samuel P Marsland Michael J Ackerman Source Type: research
Evaluation of palonosetron, fosaprepitant, and olanzapine as antiemetic prophylaxis for fludarabine and melphalan-based conditioning regimens prior to allogeneic hematopoietic stem cell transplants
CONCLUSION: The combination of palonosetron, fosaprepitant, and olanzapine is an effective antiemetic regimen for patients receiving a Flu-Mel-based preparative regimen.PMID:38043326 | DOI:10.1016/j.leukres.2023.107431 (Source: Cell Research)
Source: Cell Research - December 3, 2023 Category: Cytology Authors: Riley Karpen Jeremy Sen Sarah Wall Samantha Musson Justin Tossey Source Type: research
Breastfeeding women in need of information about antiemetics for nausea and vomiting during pregnancy: a review of inquiries to a medicines information service
Conclusion: Based on our small review of spontaneous inquiries, there seems to be an information need about the use of antiemetics during lactation among women breastfeeding an older infant whilst suffering from NVP or HG. Addressing such use in guidelines for NVP and HG and/or other easily available information sources may be considered in order to balance out the restrictive information provided by the manufacturers. This could avoid potential unnecessary weaning of breastfeeding in an otherwise challenging situation. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - November 29, 2023 Category: Drugs & Pharmacology Source Type: research
