Rethinking Ondansetron as a First Line Agent for Nausea and Vomiting in the Emergency Department
Ondansetron is commonly used as a first-line agent to treat nausea and vomiting in the Emergency Department. The purpose of this study was to test the hypothesis that Odansetron is not superior to other antiemetics, when used to treat nausea and vomiting due to headache or abdominal pain in an emergency department. The medications that were compared in the study include: ondansetron, metoclopramide, haloperidol, prochlorperazine and promethazine. (Source: The Journal of Emergency Medicine)
Source: The Journal of Emergency Medicine - March 1, 2023 Category: Emergency Medicine Authors: Melanie Camejo, Monica L. Gaddis, Phi Dinh Source Type: research
The efficacy of 5HT3-receptor antagonists in postoperative nausea and vomiting: the role of pharmacogenetics
CONCLUSIONS: This review highlights that inefficacy of a specific drug in managing PONV could be attributed to specific genetic profiles and patients would possibly benefit from a drug switch.PMID:36852569 | DOI:10.23736/S0375-9393.22.16983-X (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - February 28, 2023 Category: Anesthesiology Authors: Polyxeni Theodosopoulou Martina Rekatsina Chryssoula Staikou Source Type: research
Impact of body weight-based dosing of palonosetron and ondansetron on postoperative nausea and vomiting following laparoscopic sleeve gastrectomy: a randomized, double-blind study
CONCLUSIONS: The use of palonosetron significantly reduced the incidence of PONV following laparoscopic sleeve gastrectomy. There was significant improvement in the scores of Functional Living Index-Emesis in patients using palonosetron.PMID:36827206 (Source: Acta Chirurgica Belgica)
Source: Acta Chirurgica Belgica - February 24, 2023 Category: Surgery Authors: B üşra Burcu Nadir Adnan Hac ım Ozan Caliskan Serdar Demirgan Talar Vartanoglu Aktokmakyan Serhat Meric Tomris Duymaz Onder Karabay Ali Solmaz Source Type: research
