Pain, Nausea, and Hospital Admission Following Uterine Fibroid Embolization (UFE): A Comparison of Two Protocols
Uterine fibroid embolization (UFE) cases performed from 2013 to 2019 were reviewed. 72 patients were treated with a standard protocol consisting of sedation, ketorolac, ondansetron, and overnight parenteral analgesics and antiemetics. 96 were treated with a new protocol, which added transdermal scopolamine, lorazepam, and IV acetaminophen. Outpatient UFE (OP-UFE) was successful with 81.4% and 2.7% of patients treated with the new and old protocols, respectively (p (Source: Journal of Vascular and Interventional Radiology : JVIR)
Source: Journal of Vascular and Interventional Radiology : JVIR - December 12, 2022 Category: Radiology Authors: Geoffrey Hastings, Thomas Brahler, Gabriel Howles-Banerji, Michael Kotton, Adi Price, Daniel Singer, S. Jarrett Wrenn Tags: Brief Report Source Type: research
Pain, Nausea, and Hospital Admission after Uterine Fibroid Embolization: A Comparison of 2 Protocols
Uterine fibroid embolization (UFE) procedures performed from 2013 to 2019 were reviewed. Seventy-two patients were treated with a standard protocol consisting of sedation, ketorolac, ondansetron, and overnight parenteral analgesics and antiemetics. Ninety-six patients were treated with a new protocol, which added transdermal scopolamine, lorazepam, and intravenous acetaminophen. Outpatient uterine fibroid embolization (OP-UFE) not requiring hospitalization was successful in 81.4% and 2.7% of patients treated with the new and old protocols, respectively (odds ratio [OR], 141.4; P (Source: Journal of Vascular and Interventio...
Source: Journal of Vascular and Interventional Radiology : JVIR - December 12, 2022 Category: Radiology Authors: Geoffrey Hastings, Thomas Brahler, Gabriel Howles-Banerji, Michael Kotton, Adi Price, Daniel Singer, S. Jarrett Wrenn Tags: Brief Report Source Type: research
Combination of dexamethasone and ondansetron in prophylaxis nausea and vomiting in gynecological operation
J Popul Ther Clin Pharmacol. 2022 Dec 3;29(4):e150-e157. doi: 10.47750/jptcp.2022.984. eCollection 2022.NO ABSTRACTPMID:36464494 | DOI:10.47750/jptcp.2022.984 (Source: Journal of Population Therapeutics and Clinical Pharmacology)
Source: Journal of Population Therapeutics and Clinical Pharmacology - December 4, 2022 Category: Drugs & Pharmacology Authors: Alaq Saeed Abdulhussain Source Type: research
Inhibition of Spinal 5-HT3 Receptor and Spinal Dorsal Horn Neuronal Excitability Alleviates Hyperalgesia in a Rat Model of Parkinson ’s Disease
In conclusion, the present study suggests that inhibition of spinal 5-HT3 receptor and SDH neuronal excitability alleviates hyperalgesia in PD rats. Our study provides a novel mechanism or therap eutic strategy for pain in patients with PD. (Source: Molecular Neurobiology)
Source: Molecular Neurobiology - December 1, 2022 Category: Neurology Source Type: research
Safety evaluation of ondansetron after gestational exposure on male reproductive parameters in rats
In conclusion, prenatal exposure to ondansetron did not cause maternal toxicity, as well as did not interfere with reproductive parameters of male offspring, indicating its safety after gestational exposure in rats.PMID:36442580 | DOI:10.1016/j.yrtph.2022.105302 (Source: Regulatory Toxicology and Pharmacology : RTP)
Source: Regulatory Toxicology and Pharmacology : RTP - November 28, 2022 Category: Toxicology Authors: Ana Carolina Casali Reis B árbara Campos Jorge Julia Stein Suyane da Silva Moreira Beatriz de Matos Manoel Ariana Musa Aquino Leticia Cardoso Valente C ândida Aparecida Leite Kassuya Wellerson Rodrigo Scarano Arielle Cristina Arena Source Type: research
Safety evaluation of ondansetron after gestational exposure on male reproductive parameters in rats
In conclusion, prenatal exposure to ondansetron did not cause maternal toxicity, as well as did not interfere with reproductive parameters of male offspring, indicating its safety after gestational exposure in rats.PMID:36442580 | DOI:10.1016/j.yrtph.2022.105302 (Source: Regulatory Toxicology and Pharmacology : RTP)
Source: Regulatory Toxicology and Pharmacology : RTP - November 28, 2022 Category: Toxicology Authors: Ana Carolina Casali Reis B árbara Campos Jorge Julia Stein Suyane da Silva Moreira Beatriz de Matos Manoel Ariana Musa Aquino Leticia Cardoso Valente C ândida Aparecida Leite Kassuya Wellerson Rodrigo Scarano Arielle Cristina Arena Source Type: research
Safety evaluation of ondansetron after gestational exposure on male reproductive parameters in rats
In conclusion, prenatal exposure to ondansetron did not cause maternal toxicity, as well as did not interfere with reproductive parameters of male offspring, indicating its safety after gestational exposure in rats.PMID:36442580 | DOI:10.1016/j.yrtph.2022.105302 (Source: Regulatory Toxicology and Pharmacology : RTP)
Source: Regulatory Toxicology and Pharmacology : RTP - November 28, 2022 Category: Toxicology Authors: Ana Carolina Casali Reis B árbara Campos Jorge Julia Stein Suyane da Silva Moreira Beatriz de Matos Manoel Ariana Musa Aquino Leticia Cardoso Valente C ândida Aparecida Leite Kassuya Wellerson Rodrigo Scarano Arielle Cristina Arena Source Type: research
Aromatherapy with Isopropyl Alcohol versus Intravenous Ondansetron in Management of Mild Brain Trauma Nausea and Vomiting; a Randomized Clinical Trial
CONCLUSION: Aromatherapy using isopropyl alcohol significantly reduced nausea of patients with mild isolate head trauma after 30 minutes. Regarding vomiting, no favorable result was observed in this study. However, the frequency of vomiting was reduced in both control and intervention groups.PMID:36426172 | PMC:PMC9676696 | DOI:10.22037/aaem.v10i1.1792 (Source: Accident and Emergency Nursing)
Source: Accident and Emergency Nursing - November 25, 2022 Category: Emergency Medicine Authors: Behrang Rezvani Kakhki Tahereh Ghasemi Elnaz Vafadar Moradi Zahra Abbasi Shaye Seyed Mohammad Mousavi Source Type: research
Aromatherapy with Isopropyl Alcohol versus Intravenous Ondansetron in Management of Mild Brain Trauma Nausea and Vomiting; a Randomized Clinical Trial
CONCLUSION: Aromatherapy using isopropyl alcohol significantly reduced nausea of patients with mild isolate head trauma after 30 minutes. Regarding vomiting, no favorable result was observed in this study. However, the frequency of vomiting was reduced in both control and intervention groups.PMID:36426172 | PMC:PMC9676696 | DOI:10.22037/aaem.v10i1.1792 (Source: Accident and Emergency Nursing)
Source: Accident and Emergency Nursing - November 25, 2022 Category: Emergency Medicine Authors: Behrang Rezvani Kakhki Tahereh Ghasemi Elnaz Vafadar Moradi Zahra Abbasi Shaye Seyed Mohammad Mousavi Source Type: research
Aromatherapy with Isopropyl Alcohol versus Intravenous Ondansetron in Management of Mild Brain Trauma Nausea and Vomiting; a Randomized Clinical Trial
CONCLUSION: Aromatherapy using isopropyl alcohol significantly reduced nausea of patients with mild isolate head trauma after 30 minutes. Regarding vomiting, no favorable result was observed in this study. However, the frequency of vomiting was reduced in both control and intervention groups.PMID:36426172 | PMC:PMC9676696 | DOI:10.22037/aaem.v10i1.1792 (Source: Accident and Emergency Nursing)
Source: Accident and Emergency Nursing - November 25, 2022 Category: Emergency Medicine Authors: Behrang Rezvani Kakhki Tahereh Ghasemi Elnaz Vafadar Moradi Zahra Abbasi Shaye Seyed Mohammad Mousavi Source Type: research
The Possible Protective Effects of Ondansetron and Tropisetron on
Optic Nerve Crush Injury in Rats
Conclusion Our findings indicate that cyclosporine, ondansetron, and
tropisetron protect against ONC injury in rats, possibly via the suppression of
apoptosis and modulation of calcineurin activity directly and via 5-HT3
receptors. Moreover, immunoblotting showed that tropisetron was more effective
as opposed to ondansetron. Further studies are needed to evaluate the precise
mechanism behind cyclosporine, ondansetron, and tropisetron activities. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents ...
Source: Drug Research - November 24, 2022 Category: Drugs & Pharmacology Authors: Shayan, Maryam Eslami, Faezeh Khosravi, Ayda Rashidian, Amir Jafari, Razie Mohammad Maroufi, Seyed Farzad Golroudbari, Hasti Tashak Dehpour, Ahmad Reza Tags: Original Article Source Type: research
Effect of balanced opioid-free anaesthesia on postoperative nausea and vomiting after video-assisted thoracoscopic lung resection: protocol for a randomised controlled trial
This study aims to investigate the effects of balanced OFA on PONV and pain outcomes in patients undergoing video-assisted thoracoscopic surgery (VATS).
Methods and analysis
This randomised controlled trial will be conducted at the First Affiliated Hospital of Soochow University in Suzhou, China. A total of 120 adults scheduled for VATS lung resection will be randomly assigned with a 1:1 ratio to either an OFA group or a control group, stratified by sex (n=60 in each group). Patients will receive balanced anaesthesia with esketamine, dexmedetomidine and sevoflurane (the OFA group), or sufentanil and sevoflurane (the contr...
Source: BMJ Open - November 22, 2022 Category: General Medicine Authors: Long, Y.-q., Wang, D., Chen, S., Xu, Y., Feng, C.-d., Ji, F.-H., Cheng, H., Peng, K. Tags: Open access, Anaesthesia Source Type: research
Reduced sodium absorption in the colon under serotonin is a potential factor aggravating secretory diarrhea
CONCLUSIONS: Serotonin reduces both stationary and stimulated sodium ion absorption, thus playing an important role in the pathophysiology of secretory diarrhea. The described phenomenon depends on serotonin's action on 5-HT4 receptors.PMID:36374545 | DOI:10.17219/acem/155111 (Source: Adv Data)
Source: Adv Data - November 14, 2022 Category: Epidemiology Authors: Jaros ław Koza Ariel Liebert Iga Ho łyńska-Iwan El żbieta Piskorska Piotr Kaczorowski Source Type: research
Efficacy and Safety of Olanzapine in Children Receiving Highly Emetogenic Chemotherapy: A Randomized, Double-blind Placebo-controlled Phase 3 Trial
In this study, patients aged 3 to 18 years were randomly assigned to either the olanzapine group or the placebo group. All patients received intravenous ondansetron and dexamethasone 30 minutes before highly emetogenic chemotherapy, followed by oral ondansetron for 48 hours. Participants in the olanzapine group received olanzapine once daily on days 1 and 2, while those in the control group received a placebo in the same dosage and schedule. The primary objective was: (a) to compare the complete control rates of vomiting in the delayed phase and (b) to compare the complete control rates of vomiting in acute and overall pha...
Source: Journal of Pediatric Hematology Oncology - October 31, 2022 Category: Hematology Tags: Original Articles Source Type: research
