Antiemetic Administration and Its Association with Race: A Retrospective Cohort Study
ConclusionsIn a perioperative registry data set, Blackversus White patient race was associated with less antiemetic administration, after controlling for all accepted postoperative nausea and vomiting risk factors.Editor ’s PerspectiveWhat We Already Know about This TopicSocial determinants, such as race, may lead to disparities in health carePerioperative antiemetic administration has been found to differ with socioeconomic statusWhat This Article Tells Us That Is NewUsing data from the Multicenter Perioperative Outcomes Group registry and adjusting for Apfel postoperative nausea and vomiting risk factors, Blackversus W...
Source: Anesthesiology - May 19, 2023 Category: Anesthesiology Source Type: research
Ondansetron for the Prevention of Pruritus in Women Undergoing Cesarean Delivery With Intrathecal Opioid: A Systematic Review and Meta-Analysis
CONCLUSIONS: This systematic review has demonstrated a significant reduction in the incidence of pruritus following the use of ondansetron. This is in contrast to previously published meta-analyses. Studies included were of varying quality and some at high risk of bias with a high degree of statistical heterogeneity. Furthermore, high-quality and well-powered studies are required to confirm these findings.PMID:37167702 | DOI:10.1213/ANE.0000000000006526 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - May 11, 2023 Category: Anesthesiology Authors: Matthew Cadd Paul Jackson Baby Ewnetu Source Type: research
Ondansetron: recommended antiemetics for patients with acute pancreatitis? a population-based study
Conclusion: In ICU acute pancreatitis patients, ondansetron administration was associated with better 90-day outcomes, while results were similar in terms of in-hospital and overall outcomes, and the recommended minimum total dose might be suggested to be 4–8 mg. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - May 10, 2023 Category: Drugs & Pharmacology Source Type: research
Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low- and middle-income countries
CONCLUSIONS: In LMICs there is low-certainty evidence supporting the efficacy of combined psychosocial and pharmacologic interventions on reducing harmful alcohol use relative to psychosocial interventions alone. There is insufficient evidence to determine the efficacy of pharmacologic or psychosocial interventions on reducing harmful alcohol use largely due to the substantial heterogeneity in outcomes, comparisons, and interventions that precluded pooling of these data in meta-analyses. The majority of studies are brief interventions, primarily among men, and using measures that have not been validated in the target popul...
Source: Cochrane Database of Systematic Reviews - May 9, 2023 Category: General Medicine Authors: M Claire Greene Jeremy Kane Michelle Alto Ali Giusto Kathryn Lovero Melissa Stockton Jasmine McClendon Terriann Nicholson Milton L Wainberg Renee M Johnson Wietse Anton Tol Source Type: research
Enhanced Recovery After Surgery and Postoperative Nausea and Length of Stay in Mastectomy Patients With Reconstruction
CONCLUSIONS: Our results indicate that implementation of the ERAS protocol in women undergoing mastectomy with immediate reconstruction is associated with improved patient outcomes in postoperative nausea and LOS.PMID:37119617 | DOI:10.1016/j.jss.2023.02.003 (Source: Cancer Control)
Source: Cancer Control - April 29, 2023 Category: Cancer & Oncology Authors: Pranvera Sulejmani Lilia Lunt Monica Mazur Alison Coogan Adam Steuer Cristina O'Donoghue Andrea Madrigrano Source Type: research
Mild Traumatic Brain Injury-Induced Augmented Postsurgical Pain Is Driven by Central Serotonergic Pain-Facilitatory Signaling
CONCLUSIONS: Collectively, our results show that descending serotoninergic pain-facilitating signaling is responsible for nociceptive sensitization after mTBI and that central endogenous opioid tone opposes serotonin's effects. Understanding brain injury-related changes in endogenous pain modulation may lead to improved pain control for those with TBI undergoing surgery.PMID:37083595 | DOI:10.1213/ANE.0000000000006505 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - April 21, 2023 Category: Anesthesiology Authors: QiLiang Chen Peyman Sahbaie Karen-Amanda Irvine J David Clark Source Type: research
Mild Traumatic Brain Injury-Induced Augmented Postsurgical Pain Is Driven by Central Serotonergic Pain-Facilitatory Signaling
CONCLUSIONS: Collectively, our results show that descending serotoninergic pain-facilitating signaling is responsible for nociceptive sensitization after mTBI and that central endogenous opioid tone opposes serotonin's effects. Understanding brain injury-related changes in endogenous pain modulation may lead to improved pain control for those with TBI undergoing surgery.PMID:37083595 | DOI:10.1213/ANE.0000000000006505 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - April 21, 2023 Category: Anesthesiology Authors: QiLiang Chen Peyman Sahbaie Karen-Amanda Irvine J David Clark Source Type: research
