Ropivacaine-induced seizures evoked pain sensitization in rats: Participation of 5-HT/5-HT3R
Neurotoxicology. 2022 Oct 6:S0161-813X(22)00156-5. doi: 10.1016/j.neuro.2022.10.001. Online ahead of print.ABSTRACTDue to the increasing use of local anesthetic techniques in various healthcare settings, local anesthetic toxicity still occurs. Seizures are the most common symptom of local anesthetic toxicity. The relationship between local anesthetic-induced seizures and the sensation of pain has not been established till now. Here, we assessed the development of pain hypersensitivity after ropivacaine-induced seizures (RIS) and the influence of RIS on incision-induced postsurgical pain and formalin-induced acute inflammat...
Source: Neurotoxicology - October 9, 2022 Category: Neurology Authors: Chen-Long Yang Jun-Jie Jing Si-Yin Fu Yu-Ling Zhong Xiu-Zhu Su Zhong-Mou Shi Xiao-Zhi Wu Fei Yang Guo-Zhong Chen Source Type: research
Ropivacaine-induced seizures evoked pain sensitization in rats: Participation of 5-HT/5-HT3R
Neurotoxicology. 2022 Oct 6:S0161-813X(22)00156-5. doi: 10.1016/j.neuro.2022.10.001. Online ahead of print.ABSTRACTDue to the increasing use of local anesthetic techniques in various healthcare settings, local anesthetic toxicity still occurs. Seizures are the most common symptom of local anesthetic toxicity. The relationship between local anesthetic-induced seizures and the sensation of pain has not been established till now. Here, we assessed the development of pain hypersensitivity after ropivacaine-induced seizures (RIS) and the influence of RIS on incision-induced postsurgical pain and formalin-induced acute inflammat...
Source: Neurotoxicology - October 9, 2022 Category: Neurology Authors: Chen-Long Yang Jun-Jie Jing Si-Yin Fu Yu-Ling Zhong Xiu-Zhu Su Zhong-Mou Shi Xiao-Zhi Wu Fei Yang Guo-Zhong Chen Source Type: research
Atropine, Ondansetron, and Ketorolac: Supplemental Management of Amniotic Fluid Embolism
Conclusion: Management of AFE should include consideration of the addition of AOK to typical guidelines.PMID:36189093 | PMC:PMC9477128 | DOI:10.31486/toj.21.0107 (Source: Ochsner Journal)
Source: Ochsner Journal - October 3, 2022 Category: General Medicine Authors: Miranda Long Jane Martin Joseph Biggio Source Type: research
