Bimodal Ondansetron Pill Eases Vomiting in Gastroenteritis Bimodal Ondansetron Pill Eases Vomiting in Gastroenteritis
A single long-acting tablet prevented vomiting for significantly longer than traditional medication in most recipients, a study found.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - November 11, 2019 Category: Internal Medicine Tags: Internal Medicine News Source Type: news

Ondansetron (Zofran) vs. palonosetron (Aloxi)
Title: Ondansetron (Zofran) vs. palonosetron (Aloxi)Category: MedicationsCreated: 7/29/2019 12:00:00 AMLast Editorial Review: 7/29/2019 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - July 29, 2019 Category: Drugs & Pharmacology Source Type: news

Ondansetron (Zofran) vs. promethazine (Phenergan)
Title: Ondansetron (Zofran) vs. promethazine (Phenergan)Category: MedicationsCreated: 7/29/2019 12:00:00 AMLast Editorial Review: 7/29/2019 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - July 29, 2019 Category: Drugs & Pharmacology Source Type: news

Ondansetron (Zofran) vs. metoclopramide (Reglan)
Title: Ondansetron (Zofran) vs. metoclopramide (Reglan)Category: MedicationsCreated: 7/26/2019 12:00:00 AMLast Editorial Review: 7/26/2019 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - July 26, 2019 Category: Drugs & Pharmacology Source Type: news

Fresenius Kabi Issues Voluntary Nationwide Recall of Midazolam Injection, USP, 2 mg/2 mL Due to Reports of Blister Packages Containing Syringes of Ondansetron Injection, USP, 4 mg/2 mL
Fresenius Kabi USA is voluntarily recalling Lot 6400048 of Midazolam Injection, USP, 2 mg/2 mL packaged in a 2 mL prefilled single-use glass syringe to the hospital/user level. The product mislabeled as Midazolam Injection, USP, 2 mg/2 mL contains syringes containing and labeled as Ondansetron Injection, USP, 4 mg/2 mL. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - July 25, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Ondansetron (Zofran) vs. meclizine
Title: Ondansetron (Zofran) vs. meclizineCategory: MedicationsCreated: 7/25/2019 12:00:00 AMLast Editorial Review: 7/25/2019 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - July 25, 2019 Category: Drugs & Pharmacology Source Type: news

Ondansetron (Zofran) vs. Dramamine
Title: Ondansetron (Zofran) vs. DramamineCategory: MedicationsCreated: 7/24/2019 12:00:00 AMLast Editorial Review: 7/24/2019 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - July 24, 2019 Category: Drugs & Pharmacology Source Type: news

Ondansetron (Zofran) vs. alosetron (Lotronex)
Title: Ondansetron (Zofran) vs. alosetron (Lotronex)Category: MedicationsCreated: 7/23/2019 12:00:00 AMLast Editorial Review: 7/23/2019 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - July 23, 2019 Category: Drugs & Pharmacology Source Type: news

ondansetron (Zofran, Zofran ODT, Zuplenz)
Title: ondansetron (Zofran, Zofran ODT, Zuplenz)Category: MedicationsCreated: 3/2/2005 12:00:00 AMLast Editorial Review: 7/2/2019 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - July 2, 2019 Category: Cancer & Oncology Source Type: news

FDA Drug Safety Communication: Abnormal heart rhythms may be associated with use of Zofran (ondansetron)
[09-15-2011] The U.S. Food and Drug Administration (FDA) is informing the public of an ongoing safety review of the anti-nausea drug Zofran (ondansetron, ondansetron hydrochloride and their generics). (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - June 28, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

FDA Drug Safety Communication: Updated information on 32 mg intravenous ondansetron (Zofran) dose and pre-mixed ondansetron products
The U.S. Food and Drug Administration (FDA) is notifying health care professionals that the 32 mg, single intravenous (IV) dose of the antinausea drug Zofran (ondansetron hydrochloride) will no longer be marketed because of the potential for serious cardiac risks.   (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - June 26, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

The Mushroom Chronicles: The Case of the Poisonous Omelet
On a summer afternoon in suburban Virginia, one BLS and two ALS ambulances are dispatched to an apartment complex for three people experiencing severe abdominal pain with nausea, vomiting and diarrhea onset three hours ago. Dispatch states that the patients picked, cooked and ate mushrooms from their neighborhood courtyard around 10:00 a.m. The family is from out of the country; mother and father are in their sixties and a son who is in his thirties. They said they picked the mushrooms and cooked them in an omelet, and that after breakfast, each of them became ill. Symptoms started with severe abdominal pain, followed by n...
Source: JEMS Patient Care - May 3, 2019 Category: Emergency Medicine Authors: Jennifer Rabjohns, MFA, MD Tags: Exclusive Articles Patient Care Top Story Source Type: news

What to D.O.: Relegate Ondansetron to Auxiliary Role in Pregnancy
No abstract available (Source: Emergency Medicine News)
Source: Emergency Medicine News - March 1, 2019 Category: Emergency Medicine Tags: What to D.O. Source Type: news

Not Just Acid Reflux: The Need to Think Worst First
A previously healthy, well-appearing 42-year-old female living in a modern, high-rise apartment in downtown Los Angeles calls 9-1-1 at 5:30 am complaining of worsening of a burning, epigastric pain she had been experiencing for the last three days. She reports associated nausea and non-bloody, non-bilious vomiting, and that she couldn’t manage to get comfortable in bed until she finally decided to call for help at daybreak. During her 9-1-1 call, she reports “pain, like heartburn, that just woke me up again and I had to throw up, … and then I was sweating so much.” Using the Los Angeles Tiered Disp...
Source: JEMS Special Topics - January 13, 2019 Category: Emergency Medicine Authors: Stephen Sanko, MD, FACEP Tags: Exclusive Articles Cardiac & Resuscitation Source Type: news

Study: Ondansetron Mostly Safe in Early Pregnancy
(MedPage Today) -- Increased risk of oral clefts and ear malformations, however (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - December 19, 2018 Category: Gastroenterology Source Type: news

Cardiac Malformations Not Up With First-Trimester Ondansetron
WEDNESDAY, Dec. 19, 2018 -- First-trimester ondansetron use is associated with a small increased risk for oral cleft but no increased risk for congenital malformations or cardiac malformations, according to a study published in the Dec. 18 issue of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 19, 2018 Category: Pharmaceuticals Source Type: news

Ondansetron in Early Pregnancy Doesn't Promote Cardiac Defects Ondansetron in Early Pregnancy Doesn't Promote Cardiac Defects
The antiemetic ondansetron does not meaningfully increase the risk for congenital malformations overall when taken for nausea and vomiting early in pregnancy.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 18, 2018 Category: Consumer Health News Tags: Cardiology News Source Type: news

Morning sickness pill study finds small link to increased risk of clefts but 'not a cause for alarm'
A new study finds no association between ondansetron and an increased risk of heart-related malformations or other malformations in newborns overall. It found a small increased risk of oral clefts, including cleft lip and cleft palate, in babies born to women who used ondansetron. (Source: CNN.com - Health)
Source: CNN.com - Health - December 18, 2018 Category: Consumer Health News Source Type: news

Prevention of Post Spinal Shivering Prevention of Post Spinal Shivering
This study evaluated the efficacy of dexmedetomidine and ondansetron to reduce the incidence and severity of shivering after intrathecal blocks.BMC Anesthesiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 18, 2018 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

Ondansetron Hydrochloride Injection (Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - October 18, 2018 Category: Drugs & Pharmacology Source Type: news

Ondansetron Hydrochloride Injection (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - October 11, 2018 Category: Drugs & Pharmacology Source Type: news

Ondansetron Dosing in C-Section Under Spinal Anesthesia Ondansetron Dosing in C-Section Under Spinal Anesthesia
What is the minimal weight-based dose of ondansetron required to reduce hypotension after spinal anesthesia in women undergoing cesarean section?BMC Anesthesiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 26, 2018 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

More Data Indicate Ondansetron Is Safe for Morning Sickness More Data Indicate Ondansetron Is Safe for Morning Sickness
A large data set composed of two birth defect studies confirms there is little risk for teratogenicity when off-label ondansetron is taken for nausea and vomiting during the first trimester of pregnancy.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 20, 2018 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news

Ondansetron Hydrochloride Injection (Updated - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - April 18, 2018 Category: Drugs & Pharmacology Source Type: news

Ondansetron Hydrochloride Injection (New - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - April 17, 2018 Category: Drugs & Pharmacology Source Type: news

Zuplenz (Ondansetron Oral Soluble Film) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 26, 2018 Category: Drugs & Pharmacology Source Type: news

FDA Drug Safety Communication: New information regarding QT prolongation with ondansetron (Zofran)
The U.S. Food and Drug Administration (FDA) is informing healthcare professionals and the public that preliminary results from a recently completed clinical study suggest that a 32 mg single intravenous dose of ondansetron (Zofran, ondansetron hydrochloride, and generics) may affect the electrical activity of the heart (QT interval prolongation), which could pre-dispose patients to develop an abnormal and potentially fatal heart rhythm known as Torsades de Pointes. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - December 11, 2017 Category: Drugs & Pharmacology Source Type: news

Case series: treating cannabinoid hyperemesis syndrome with capsaicin cream
3 out of 5 stars Resolution of cannabis hyperemesis syndrome with topical capsaicin in the emergency department: a case series. Dezieck L et al. Clin Toxicol 2017 Sep;55:908-913. Abstract  Cannabis hyperemesis syndrome (CHS) is a form of cyclic vomiting characterized by: chronic marijuana use recurrent vomiting, and lack of alternate explanation for symptoms A striking feature is that although CHS-induced nausea and vomiting are frequently resistant to standard antiemetics such as ondansetron, patients often report that very hot showers or baths relieve their symptoms. Several years ago, Jeff Lapoint ...
Source: The Poison Review - December 5, 2017 Category: Toxicology Authors: Leon Gussow Tags: Medical cannabinoid hyperemesis syndrome capsaicin treatment TRPV1 receptor Source Type: news

Fresenius Kabi Issues Voluntary Nationwide Recall of Midazolam Injection, USP, 2 mg/2 mL Due to Reports of Blister Packages Containing Syringes of Ondansetron Injection, USP, 4 mg/2 mL
Fresenius Kabi USA is voluntarily recalling Lot 6400048 of Midazolam Injection, USP, 2 mg/2 mL packaged in a 2 mL prefilled single-use glass syringe to the hospital/user level. The product mislabeled as Midazolam Injection, USP, 2 mg/2 mL contains syringes containing and labeled as Ondansetron Injection, USP, 4 mg/2 mL. (Source: Food and Drug Administration)
Source: Food and Drug Administration - November 3, 2017 Category: Food Science Source Type: news

Hands On Product Reviews October 2017
Ready-to-Go Training Kits Your department just decided to enhance the training program and offer certification courses in addition to the required continuing education classes. There are now hundreds of new items on your to-do list: You need to address curriculum, recruiting, staffing, scheduling and ordering the equipment required for the course. The new Loaded ALS, BLS and Medication Training Packs from DiaMedical let you take several items off your to-do list. Complete and customizable, these packs have everything you need, from airway to Zofran (simulated, of course). The BLS Pack includes a complete set of oropharyng...
Source: JEMS Operations - October 4, 2017 Category: Emergency Medicine Authors: Fran Hildwine, BS, NREMT-P Tags: Columns Operations Equipment & Gear Source Type: news

Droperidol + OND and DEX in Children for Postop Vomiting Droperidol + OND and DEX in Children for Postop Vomiting
The combination of dexamethasone, ondansetron, and droperidol has been shown to be effective in preventing postoperative nausea and vomiting in adults. Is it safe and effective for children?British Journal of Anaesthesia (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 3, 2017 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

Looking for relief, pregnant women turn to marijuana despite medical advice
According to data from the Centers for Disease Control and Prevention ’s National Vital Statistics Reports, more than one in five U.S. births now occur in states where marijuana is legal. That ’s triggered a concern among health professionals about the use of marijuana by pregnant women.Along with the broader availability of marijuana comes the perception that it is a harmless substance, health professionals say. But pregnant women, who may be seeking relief from a variety of ailments, should be aware of the potential health consequences of marijuana use.To understand how marijuana affects expectant mother...
Source: UCLA Newsroom: Health Sciences - March 2, 2017 Category: Universities & Medical Training Source Type: news

Ondansetron Hydrochloride (Zofran) (Ondansetron Hydrochloride Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 23, 2017 Category: Drugs & Pharmacology Source Type: news

Ondansetron Hydrochloride (Zofran) (Ondansetron Hydrochloride Tablets) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 23, 2017 Category: Drugs & Pharmacology Source Type: news

Off Script- You might not want to be so hasty in writing off-hand prescriptions for your friends and family.
Conclusion We went into medicine to help people. It seems so easy to just write the antibiotic prescription when a nurse says she has a UTI and she tells you that she even dipped her own urine. Don’t get me wrong: having the privilege of writing prescriptions is a perk of the profession. However, we need to follow the policies that we’ve agreed to through our board of medicine (appropriate evaluation and documentation), not use hospital equipment for work not involving hospital patients, and be aware of the malpractice risk when we care for people off the books. Dr. Silverman is chairman of emergency medicine a...
Source: EPMonthly.com - November 21, 2016 Category: Emergency Medicine Authors: Taja Whitted Tags: Uncategorized Source Type: news

Zofran Oral Solution (New - Discontinuation)
Updated Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - November 17, 2016 Category: Drugs & Pharmacology Source Type: news

Zofran (Ondansetron Hydrochloride Tablets and Solution) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 16, 2016 Category: Drugs & Pharmacology Source Type: news

I Have Morning Sickness PTSD
I threw up every day for 9 months when I was pregnant with my daughter six years ago. The medical term for severe morning sickness is "hyperemesis-gravidarum" and until Princess Kate made it evening news, many people didn't understand how incapacitating it is. For the first three months, I was bedridden and every morning felt like Groundhog's Day meets The Hangover. Everyone marveled at my growing bump and glowing skin; I was supposed to be euphoric but I existed in a torturous, alienating sick twilight zone where every morning felt like the worst hangover of all time. My 5am alarm clock was a combination of bar...
Source: Healthy Living - The Huffington Post - October 5, 2016 Category: Consumer Health News Source Type: news

Lincoln Pharma launches Ondansetron oral spray in India
Ondansetron is used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - September 22, 2016 Category: Pharmaceuticals Source Type: news

Ondansetron for pediatric concussion; a pilot study for a randomized controlled trial - Gravel J, Carri ère B, D'Angelo A, Crevier L, Beauchamp MH, Masse B.
OBJECTIVES: Assess the feasibility of a study evaluating one dose of oral ondansetron to decrease post-concussion symptoms at one week and one month following concussion in children aged 8 to 17 years old. METHOD: This was a pilot study for a rando... (Source: SafetyLit)
Source: SafetyLit - September 15, 2016 Category: Global & Universal Tags: Age: Adolescents Source Type: news

Fentanyl can cause serotonin syndrome
3.5 out of 5 stars Serotonin Syndrome Induced by Fentanyl in a Child: Case Report. Robles LA. Clin Neuropharmacol 2015 Sept-Oct;38:206-8. Abstract When many clinicians think of serotonin syndrome (SS), they consider the usual suspects: Selective Serotonin Uptake Inhibitors (SSRIs) Citalopram Fluoxetine Sertraline Escitalopram Paroxetine Serotonin-Norepinephrine Reuptake Inhibitors Venlafaxine Duloxetine Antidepressants Trazodone Buspirone Clomipramine Aside from these common culprits, there are other commonly used drugs whose clear association with serotonin syndrome is less-often realized: Fentanyl ...
Source: The Poison Review - July 8, 2016 Category: Toxicology Authors: Leon Gussow Tags: Medical fentanyl opioid serotonin syndrome Source Type: news

Dr Reddy's recalls 50,000 bottles of Ondansetron tablets in US
Dr Reddy's Laboratories Inc is recalling 50,280 bottles of Ondansetron tablets 4 mg in a ongoing recall due to "failed impurities/degradation specification (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - May 18, 2016 Category: Pharmaceuticals Source Type: news

Weighing The Risks And Benefits Of A Drug Prescribed To Pregnant Women For Extreme Morning Sickness
A new study suggests that the drug ondansetron, sold as Zofran, does not increase the risk of birth defects when taken for severe nausea and vomiting during pregnancy. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - May 15, 2016 Category: Pharmaceuticals Authors: Rita Rubin Source Type: news

Study: No link between birth defects, anti-nausea drug
Stephen FellerLOS ANGELES, May 9 (UPI) -- There is no evidence pregnant women taking Zofran for morning sickness are increasing the risk for birth defects, a new study shows, rebutting recent concerns. (Source: Health News - UPI.com)
Source: Health News - UPI.com - May 9, 2016 Category: Consumer Health News Source Type: news

No evidence found linking anti-nausea drug to birth defects
No evidence has been found to link the anti-nausea drug Zofran to an increased risk of birth defects. In fact, women with the condition who took Zofran reported fewer miscarriages and pregnancy terminations and higher live birth rates than women with extreme morning sickness who did not take the drug. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 9, 2016 Category: Science Source Type: news

Ondansetron Should Not Be First Choice for Nausea in PregnancyOndansetron Should Not Be First Choice for Nausea in Pregnancy
Ondansetron was associated with a low risk for birth defects in neonates who were exposed during the first trimester of pregnancy, and the incidence of cardiac malformations may be increased slightly. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 8, 2016 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news

TGen helps track down deadly bloodstream infection
(The Translational Genomics Research Institute) The Translational Genomics Research Institute (TGen), working with international investigators, have discovered the source of a potential deadly blood infection in more than 50 South American cancer patients. All of the patients infected with S. Kiliense received ondansetron from the same source, a pharmaceutical company in Columbia. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 17, 2016 Category: Global & Universal Source Type: news

Comunicado de la FDA sobre la seguridad de los medicamentos: Información actualizada sobre la dosis intravenosa de 32 mg de ondansetrón (Zofran) y productos previamente mezclados de ondansetrón
[12-5-12] La Administración de Alimentos y Medicamentos de Estados Unidos (FDA por sus siglas en inglés) notificó a los profesionales de la salud que ya no se comercializará la dosis intravenosa de 32 mg de Zofran (hidrocloruro de ondansetrón), un medicamento para prevenir las náuseas, debido al potencial de serios riesgos para el corazón (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 19, 2016 Category: Drugs & Pharmacology Source Type: news

Ondansetron in PregnancyOndansetron in Pregnancy
Ondansetron is frequently prescribed for morning sickness, but is it safe? Medscape Pharmacists (Source: Medscape ObGyn and Womens Health Headlines)
Source: Medscape ObGyn and Womens Health Headlines - December 4, 2015 Category: OBGYN Tags: Pharmacist Ask the Expert Source Type: news