Indicaions to surgery for lung tuberculomas today
Conclusions: Examination of surgical material ensures verification of the diagnosis, determination of MDR/XDR MBT and lung cells, creates conditions for adequate chemotherapy. All of these proves the necessity of surgical treatment for lung tuberulomas. (Source: European Respiratory Journal)
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Krasnikova, E., Lepeha, L., Tarasov, R., Erokhina, M., Aliev, V., Sadovnikova, S., Bagirov, M. Tags: Tuberculosis Source Type: research

Idiopathic granulomatous hypophysitis presenting with galactorrhea, headache, and nausea in a woman: a case report and review of the literature
ConclusionsIdiopathic granulomatous hypophysitis, a rare inflammatory disease of the pituitary gland, is a diagnosis of exclusion for which both medical and surgical management are reported in the literature. We present a case of idiopathic granulomatous hypophysitis who was symptom free with no complications of hypopituitarism following its transsphenoidal resection after 9  months of follow-up. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - November 15, 2019 Category: General Medicine Source Type: research

Granulomatosis with Polyangiitis (GPA) in a 15-year-old girl with facial Acne-like ulcers: A Case Report.
We described a 15-year-old female with a history of six months of acne-like facial and peri-auricular lesions. She had received the conventional treatment for acne (antibiotics + topical corticosteroid) with no response. She also had a history of chronic coughs which always diagnosed and treated as sinusitis. In addition, she had a history of frequent dysuria which always diagnosed and treated as urinary tract infection. Given the history, with suspicion of a multi-systemic disease such as vasculitis; we performed some diagnostic laboratory and radiologic tests in order to rule out the possible etiologies. The results show...
Source: Infectious Disorders Drug Targets - November 13, 2019 Category: Infectious Diseases Authors: Jamali Moghadam SR, Salehi MR, Mojtahedi SY, Fadaei N, Dadras O, Seyed Alinaghi SA, Mohammadifirouzeh M Tags: Infect Disord Drug Targets Source Type: research

Capillaroscopic findings in Turkish Takayasu arteritis patients
Conclusion: Capillaroscopic abnormalities are frequently seen in TA patients. We consider that abnormal capillaroscopic findings in TA patients reflect the impaired blood flow due to narrowed or occluded arteries rather than the primary capillary involvement of the disease process. PMID: 31648432 [PubMed - in process] (Source: Turkish Journal of Medical Sciences)
Source: Turkish Journal of Medical Sciences - October 29, 2019 Category: General Medicine Tags: Turk J Med Sci Source Type: research

Strawberry Gingivitis – Challenges in the diagnosis of granulomatosis with polyangiitis on gingival specimens
Publication date: Available online 2 August 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Bilal Msallem, Stefano Bassetti, Matthias S. Matter, Florian M. ThieringerAbstractStrawberry gingivitis is a rare oral manifestation of granulomatosis with polyangiitis (GPA, formerly known as Wegener's granulomatosis). It manifests as a red-purple hyperplastic gingivitis that frequently goes unrecognized as a disease-specific symptom, especially if it is the primary and only manifestation of the disease. GPA is a systemic necrotizing granulomatous vasculitis that takes a fatal course without tre...
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - August 2, 2019 Category: ENT & OMF Source Type: research

Strawberry Gingivitis – Challenges in the diagnosis of granulomatosis with polyangiitis on gingival specimens
Strawberry gingivitis is a rare oral manifestation of granulomatosis with polyangiitis (GPA, formerly known as Wegener's granulomatosis). It manifests as a red-purple hyperplastic gingivitis that frequently goes unrecognized as a disease-specific symptom, especially if it is the primary and only manifestation of the disease. GPA is a systemic necrotizing granulomatous vasculitis that takes a fatal course without treatment. Oral health care providers, who are among the first to examine the oral cavity, should be familiar with its typical appearance, clinical course, diagnostic parameters and management. (Source: Oral Surger...
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - August 1, 2019 Category: ENT & OMF Authors: Bilal Msallem, Stefano Bassetti, Matthias S. Matter, Florian M. Thieringer Tags: Case Report Source Type: research

Strawberry gingivitis: Challenges in the diagnosis of granulomatosis with polyangiitis on gingival specimens
Strawberry gingivitis is a rare oral manifestation of granulomatosis with polyangiitis (GPA, formerly known as Wegener's granulomatosis). It manifests as a red-purple hyperplastic gingivitis that frequently goes unrecognized as a disease-specific symptom, especially if it is the primary and only manifestation of the disease. GPA is a systemic necrotizing granulomatous vasculitis that takes a fatal course without treatment. Oral health care providers, who are among the first to examine the oral cavity, should be familiar with its typical appearance, clinical course, diagnostic parameters, and management. (Source: Oral Surge...
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - August 1, 2019 Category: ENT & OMF Authors: Bilal Msallem, Stefano Bassetti, Matthias S. Matter, Florian M. Thieringer Tags: Case Report Source Type: research

Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

[ANCA-associated vasculitides : State of the art].
Abstract Granulomatosis with polyangiitis (GPA, formerly Wegener's granulomatosis) and microscopic polyangiitis (MPA) are associated with the detection of antibodies against neutrophilic cytoplasmic antigens (ANCA) and are referred to as ANCA-associated vasculitides (AAV). In the event of the clinical suspicion of AAV the ANCA should first be determined by means of an antigen-specific immunoassay for proteinase 3‑ANCA and myeloperoxidase-ANCA, according to current consensus recommendations. The diagnosis of AAV should also be confirmed by biopsy if possible. The classification criteria for AAV are curren...
Source: Zeitschrift fur Rheumatologie - April 25, 2019 Category: Rheumatology Authors: Hellmich B Tags: Z Rheumatol Source Type: research

Wegener's Granolomatosis Presenting as Wallenberg Syndrome: A Case Report
Granulomatosis with polyangiitis (GPA), formerly known as Wegener's granulomatosis, a vasculitis affecting small and medium sized vessels usually affects the upper and lower respiratory tract, the kidneys, and the eyes. Neurologic manifestation in central nervous system (CNS) is less frequent than the peripheral and usually is in form of stroke. Few cases of lateral medullary ischemic stroke (Wallenberg syndrome) due to GPA have been reported. A 41 year-old female, presented with acute vertigo, nausea/vomiting, hiccups, dysphagia. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 22, 2019 Category: Neurology Authors: Maziar Emamikhah, Farzad Sina, Mahisa Mokhtari, Fatemeh Shirani, Mohammadreza Asadipanah Tags: Case Report Source Type: research

Wegener's Granulomatosis Presenting as Wallenberg Syndrome: A Case Report
Granulomatosis with polyangiitis (GPA), formerly known as Wegener's granulomatosis, a vasculitis affecting small and medium sized vessels usually affects the upper and lower respiratory tract, the kidneys, and the eyes. Neurologic manifestation in central nervous system (CNS) is less frequent than the peripheral and usually is in form of stroke. Few cases of lateral medullary ischemic stroke (Wallenberg syndrome) due to GPA have been reported. A 41 year-old female, presented with acute vertigo, nausea/vomiting, hiccups, dysphagia. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 22, 2019 Category: Neurology Authors: Maziar Emamikhah, Farzad Sina, Mahisa Mokhtari, Fatemeh Shirani, Mohammadreza Asadipanah Tags: Case Report Source Type: research

A boy in his teens with large ulcerations of the head and neck.
We present a case of a teenage boy with pyoderma gangrenosum-like ulcerations of the neck and face. Anti-neutrophil cytoplasmic antibody with antigen specificity for proteinase 3 (PR3-ANCA) was detected. In the absence of other symptoms and organ manifestations, the ulcerations were still considered to be pyoderma gangrenosum. The ulcers started to heal during treatment with corticosteroids and infliximab. One month later the patient developed sinusitis, and eventually lost vision in his left eye. The diagnosis was changed to GPA and he started treatment with methylprednisolone, rituximab and cyclophosphamide with good res...
Source: Tidsskrift for den Norske Laegeforening - April 8, 2019 Category: General Medicine Authors: Moen BH, Nystad TW, Barrett TM, Sandvik LF Tags: Tidsskr Nor Laegeforen Source Type: research

Impact and safety of open lung biopsy in patients with acute respiratory distress syndrome (ARDS)
ConclusionThe information provided by OLB performed at the bedside in ARDS patients of unknown etiology could be relevant, as it may optimize treatment. The risk associated with OLB seems to be acceptable.ResumenIntroducciónEl síndrome de dificultad respiratoria aguda (ARDS, acute respiratory distress syndrome) es una enfermedad pulmonar inflamatoria y su característica distintiva patológica es el daño alveolar difuso (DAD, diffuse alveolar damage). Dado que la biopsia pulmonar abierta (OLB, open lung biopsy) a veces puede dar lugar a efectos secundarios graves, rara vez se realiza en pacientes con SDRA.ObjetivosLos o...
Source: Medicina Intensiva - March 30, 2019 Category: Intensive Care Source Type: research

P.02.35 intestinal involvement in wegener's granulomatosis mimicking an inflammatory bowel disease: a case report
(Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - March 24, 2019 Category: Gastroenterology Authors: F. Pelizzaro, M. Ghisa, B. Bareberio, I. Barbuscio, M. Della Coletta, E. Cocconcelli, F. Schiavon, E.V. Savarino, F. Farinati, F. Galeazzi Tags: Posters Source Type: research

Non-squamous cell carcinoma diseases of the larynx: clinical and imaging findings
ConclusionImaging studies may provide clues for diagnosis of non-squamous cell laryngeal lesions. Clinical and imaging findings and previous clinical history should be evaluated together in clinical management of laryngeal lesions.ResumoIntroduçãoO carcinoma de células escamosas é a neoplasia laríngea mais comum, representando aproximadamente 95% de todas as neoplasias malignas da laringe. No entanto, vários outros tumores benignos e malignos, e doenças inflamatórias, podem afetar a laringe.ObjetivoO objetivo deste estudo é analisar os achados clínicos e de imagem de neoplasias de células não-escamosas e de doe...
Source: Brazilian Journal of Otorhinolaryngology - March 17, 2019 Category: ENT & OMF Source Type: research