Anti-cyclic citrullinated peptide antibody in psoriatic arthritis: a  meta-analysis of its frequency and association with clinical features.
This study aimed to investigate the frequency of the anti-cyclic citrullinated peptide (anti-CCP) antibody in patients with psoriatic arthritis (PsA) and to assess its associations with clinical features of this disease. METHODS: The Medline, EMBASE, and Cochrane databases were searched for studies that examined anti-CCP antibodies in patients with PsA. Meta-analyses of the frequency of the anti-CCP antibody in these patients and its association with polyarthritis, bone erosion, dactylitis, and enthesitis were then performed. RESULTS: Fourteen studies with a combined total of 3291 patients with PsA met the i...
Source: Zeitschrift fur Rheumatologie - July 8, 2019 Category: Rheumatology Authors: Kim KY, Lee YH Tags: Z Rheumatol Source Type: research

[Rheumatological care in the Rheumazentrum Ruhrgebiet Rheumatism Center-a model for conurbations].
s X Abstract The Ruhrgebiet Rheumatism Center, which is highly specialized for rheumatic diseases, is the largest of its kind in Germany. For many years it has fulfilled all the requirements for structural quality required by the Association of Rheumatological Acute Clinics (VRA) including regular participation in the KOBRA benchmarking project. Therefore, the center regularly receives the VRA seal for quality of care. In 2018 more than 7500 patients were treated as inpatients. Within the framework of care according to §116b (ASV since May 2019) there were nearly 25,000 outpatient patient contacts. Furthermor...
Source: Zeitschrift fur Rheumatologie - July 8, 2019 Category: Rheumatology Authors: Braun J, Kiltz U, Andreica I, Buehring B, Guminski B, Häusler U, Kavruk H, Kiefer D, Lochowski R, Mintrop B, Baraliakos X Tags: Z Rheumatol Source Type: research

[Reality of care for musculoskeletal diseases at the population level : Results of the PROCLAIR collaborative project. German version].
The objective of the research consortium PROCLAIR was to gain population level knowledge on the treatment of patients with rheumatoid arthritis (RA), axial spondylarthritis (axSpA) and osteoarthritis (OA) in Germany. AIMS: A main question of the consortium was whether it is possible to identify groups of people who were exposed to a particular risk of undersupply or oversupply of treatment. In addition, the study investigated the validity of claims data for these diseases as a basis for further studies. PATIENTS AND METHODS: Cross-sectional surveys were carried out among insurees of the BARMER statutory...
Source: Zeitschrift fur Rheumatologie - July 4, 2019 Category: Rheumatology Authors: Callhoff J, Albrecht K, Hoffmann F, Poddubnyy D, Günther KP, Zink A Tags: Z Rheumatol Source Type: research

[Rivaroxaban versus warfarin in high-risk patients with antiphospholipid syndrome].
PMID: 31250081 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - June 27, 2019 Category: Rheumatology Authors: Hadjiski D Tags: Z Rheumatol Source Type: research

[Three years of the appointment service office: high rate of false referrals and no show patients-A  retrospective anaysis of the Rheumatism Center Schleswig-Holstein Mitte].
This article presents a retrospective analysis of patients who attended a rheumatology specialist practice (with two specialist rheumatologists) between 2016 and 2018 via an appointment arranged by the appointment service office (Terminservicestelle, TSS). Patients were analyzed in a pseudonymized manner and categorized according to the following criteria: 1. patient did not keep the appointment, 2. patient had no inflammatory rheumatic disease, 3. patient suffered from an inflammatory rheumatic disease but had no urgent indications to be seen and 4. patient suffered from an inflammatory rheum...
Source: Zeitschrift fur Rheumatologie - June 13, 2019 Category: Rheumatology Authors: Holle JU, Moosig F Tags: Z Rheumatol Source Type: research

[Hot topic: direct oral anticoagulants (DOAC) in antiphospholipid syndrome?]
r M PMID: 31197460 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - June 13, 2019 Category: Rheumatology Authors: Specker C, Dörner T, Schneider M Tags: Z Rheumatol Source Type: research

Neuropathic pain in ankylosing spondylitis: a  meta-analysis.
CONCLUSION: The current meta-analysis showed that NP patients had significantly higher pain severity, higher disease activity and lower quality of life than Non-NP patients. The sex ratio (F/M) and proportion of HLA-B27 positive patients were different between the two groups. Further well-designed studies are needed to substantiate our results. PMID: 31165930 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - June 5, 2019 Category: Rheumatology Authors: Kim TW, Son SM, Lee JS Tags: Z Rheumatol Source Type: research

[ADAPTHERA-Statewide cross-sectoral care network for patients with early rheumatoid arthritis shows sustained remission in standard care].
DISCUSSION: The approach of a supply network is not a panacea, but it might improve healthcare for patients with early onset RA. In order to minimize resource utilization, a pinpoint referral and accurate triage of potential cases are crucial. PMID: 31165251 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - June 4, 2019 Category: Rheumatology Authors: Lauter A, Triantafyllias K, Leiß R, Amberger C, Engels J, Hesse M, Jendro M, Gilly J, Stadelmann ML, Ziese W, Wollschläger D, Dreher M, Pfeiff B, Weinmann-Menke J, Panholzer T, Schwarting A Tags: Z Rheumatol Source Type: research

[Special treatment in rheumatology-cross-sectoral quality-oriented selective contracts].
Abstract In the last 4 years selective contracts according to §140a of the German Social Code Book V (SGB V) with three different health insurers were signed by the Professional Association of German Rheumatologists (BDRh) and from the beginning of the year 2018 by the management company of the association. The contracts were rolled out in five regions of Germany (Bavaria, Hesse, Mecklenburg-Western Pomerania, North Rhine and Saxony). Up to the end of 2018, 12,000 patients with chronic inflammatory rheumatic diseases were treated within the managed care of these contracts. The interface and the trea...
Source: Zeitschrift fur Rheumatologie - June 3, 2019 Category: Rheumatology Authors: Edelmann E, Schuch F, Kalthoff L, Zinke S Tags: Z Rheumatol Source Type: research

[New therapy approaches, better outcomes? : Results from inception cohorts for patients with juvenile idiopathic arthritis].
Abstract Prospective cohort studies collect demographic and clinical data of newly diagnosed patients using standardized questionnaires and validated measuring instruments. Therefore, they are a valuable data source for evaluating disease progression, outcome parameters and predictors. In this article a selection of results from four inception cohorts on juvenile idiopathic arthritis (JIA) are presented. In all cohorts, one half to three quarters of the patients achieved an inactive disease within the first year under observation but there were relevant differences between the different JIA categories. T...
Source: Zeitschrift fur Rheumatologie - May 24, 2019 Category: Rheumatology Authors: Sengler C Tags: Z Rheumatol Source Type: research

[New drugs for treatment of juvenile idiopathic arthritis].
This article discusses innovations in biologics and the importance of the latest group for targeted therapy with small molecules in pediatric rheumatology. PMID: 31098699 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - May 16, 2019 Category: Rheumatology Authors: Horneff G Tags: Z Rheumatol Source Type: research

[Systemic sclerosis-clinical picture, diagnosis, and treatment].
Abstract Systemic sclerosis is a rare rheumatologic disease that is characterised by skin and organ fibrosis as well as vascular changes and the occurrence of specific autoantibodies. It has a high morbidity and mortality while its manifestations show significant heterogeneity in patients. Thus, diagnosis and follow-up of patients with systemic sclerosis has to be extensive, the more so because treatment must adapted to organ manifestations. Although specific therapies for gastrointestinal, pulmonary or vascular complications exist, patients respond only partly to these and new therapeutic approaches are...
Source: Zeitschrift fur Rheumatologie - May 14, 2019 Category: Rheumatology Authors: Becker MO, Distler O, Maurer B Tags: Z Rheumatol Source Type: research

[Juvenile dermatomyositis-what's new?]
Abstract Juvenile dermatomyositis (JDM) is the most common chronic inflammatory myopathy of childhood, which is still frequently characterized by a complicated disease course. In this review, novel findings relating to JDM are presented based on a review of the literature. Myositis-specific antibodies are often detected and may correlate with clinical phenotypes and disease course. Activation of type I interferon pathways plays an important pathogenic role and relates to the main clinical manifestations of the disease. This may lead to targeted therapies in the future. Currently, there are no treatm...
Source: Zeitschrift fur Rheumatologie - May 13, 2019 Category: Rheumatology Authors: Hinze C Tags: Z Rheumatol Source Type: research

[Biologics in the treatment of juvenile idiopathic arthritis : A comparison of mono- and combination therapy with synthetic DMARDs].
Abstract In polyarticular juvenile idiopathic arthritis, methotrexate (MTX) is still used as first-line treatment. In case of insufficient response or intolerance, a number of biologics are now available. This faces physicians with challenging choices. Biologics are often combined with MTX, although in JIA there is little evidence and inconsistent results from various studies. In rheumatoid arthritis, combination therapy with tumor necrosis factor (TNF) inhibitors has been associated with higher efficacy. Tocilizumab appears to be highly effective as a monotherapy. MTX has a protective effect on the...
Source: Zeitschrift fur Rheumatologie - May 13, 2019 Category: Rheumatology Authors: Klein A Tags: Z Rheumatol Source Type: research

[Survey of rheumatologists in Saxony, Saxony-Anhalt and Thuringia regarding the occupational situation and activities in further education: no way out of the undersupply of rheumatological care].
ringer M Abstract INTRODUCTION: Many regions in the middle of Germany have a deficit in specialized rheumatological care. A survey was undertaken to investigate whether the regional capacities for rheumatological advanced training are sufficient to provide an adequate number of rheumatologists in the future. METHODS: All 91 rheumatologists registered in Saxony, Saxony-Anhalt and Thuringia received a questionnaire that was sent back by 66% of the recipients (23 responses from Saxony, 19 from Saxony-Anhalt, 18 from Thuringia). Of the rheumatologists 41 were in private practice, 19 worked in ...
Source: Zeitschrift fur Rheumatologie - May 13, 2019 Category: Rheumatology Authors: Keyßer G, Baerwald CGO, Sieburg M, Boche K, Pfeil A, Kupka TA, Lüthke K, Heldmann F, Oelzner P, Unger L, Aringer M Tags: Z Rheumatol Source Type: research

[MTX intolerance in children and adolescents with juvenile idiopathic arthritis].
e B Abstract Methotrexate (MTX) is the medication most commonly used for antirheumatic treatment in juvenile idiopathic arthritis. It has high efficacy, is usually well tolerated and has an excellent safety profile. However, intolerance symptoms frequently develop, which manifest as nausea, feelings of disgust, or abdominal complaints prior to or directly after application of the medication. A direct side effect can usually be easily excluded; however, the symptoms are limited to treatment with MTX. This MTX intolerance causes a significant reduction in the quality of life of affected patients, frequentl...
Source: Zeitschrift fur Rheumatologie - May 7, 2019 Category: Rheumatology Authors: Hügle B Tags: Z Rheumatol Source Type: research

Colchicine's Effects on Electrocardiographic Parameters in Newly Diagnosed Familial Mediterranean Fever Patients : Colchicine may have Favourable Effects on Parameters Related to Ventricular Arrhythmias in New Diagnosed Familial Mediterranean Fever.
CONCLUSION: Colchicine treatment may have a favourable effect on ventricular repolarisation indices that relate to ventricular arrhythmia and sudden death. PMID: 31065792 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - May 7, 2019 Category: Rheumatology Authors: Ocal AG, Ocal L, Kup A, Eren H, Tezcan ME Tags: Z Rheumatol Source Type: research

[Comorbidities-Their role in the treat to target concept for rheumatoid arthritis].
z C Abstract Treat to target (T2T) strategies and comorbidities are closely related. Strong evidence exists for reducing the risk and extent of comorbidities, such as cardiovascular (CV) diseases, depression and infections by implementing T2T concepts and inducing good disease control of rheumatoid arthritis (RA) in this way. On the other hand existing comorbidities may hinder implementation of T2T concepts by aggravating RA or influencing rheumatologists to overcautiously use DMARD treatment. Among a long list of potentially relevant comorbidities with RA, in this review two particularly relevant accompanyin...
Source: Zeitschrift fur Rheumatologie - May 2, 2019 Category: Rheumatology Authors: Krüger K, Kneitz C Tags: Z Rheumatol Source Type: research

[Eosinophilic diseases in rheumatology].
PMID: 31049697 [PubMed - in process] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - May 1, 2019 Category: Rheumatology Authors: Hellmich B, Moosig F Tags: Z Rheumatol Source Type: research

Hot Topic: Komorbidit äten.
Hot Topic: Komorbiditäten. Z Rheumatol. 2019 May;78(4):302-303 Authors: PMID: 31049698 [PubMed - in process] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - May 1, 2019 Category: Rheumatology Tags: Z Rheumatol Source Type: research

Mitteilungen der DGRh.
Authors: PMID: 31049699 [PubMed - in process] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - May 1, 2019 Category: Rheumatology Tags: Z Rheumatol Source Type: research

Mitteilungen der DRL.
Authors: PMID: 31049700 [PubMed - in process] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - May 1, 2019 Category: Rheumatology Tags: Z Rheumatol Source Type: research

[ANCA-associated vasculitides : State of the art].
Abstract Granulomatosis with polyangiitis (GPA, formerly Wegener's granulomatosis) and microscopic polyangiitis (MPA) are associated with the detection of antibodies against neutrophilic cytoplasmic antigens (ANCA) and are referred to as ANCA-associated vasculitides (AAV). In the event of the clinical suspicion of AAV the ANCA should first be determined by means of an antigen-specific immunoassay for proteinase 3‑ANCA and myeloperoxidase-ANCA, according to current consensus recommendations. The diagnosis of AAV should also be confirmed by biopsy if possible. The classification criteria for AAV are currently bein...
Source: Zeitschrift fur Rheumatologie - April 26, 2019 Category: Rheumatology Authors: Hellmich B Tags: Z Rheumatol Source Type: research

[State of the art: systemic lupus erythematosus].
Abstract As long as we cannot cure diseases such as systemic lupus erythematosus (SLE), it must be our goal that people with SLE can live a largely normal life. It should not be dominated by the disease. The main goal is secondary prevention, i. e. the prevention of harm. In 2020 we want to make a better contribution to this aim. For this article on SLE, being fit for 2020 therefore means applying the basic concepts of care for patients with SLE on a regular basis. The focus is on the new concepts resulting from the new classification criteria, the optimized basic care (BASIC), the complex communi...
Source: Zeitschrift fur Rheumatologie - April 26, 2019 Category: Rheumatology Authors: Mucke J, Fischer-Betz R, Schneider M Tags: Z Rheumatol Source Type: research

[Depressive symptoms in early rheumatoid arthritis : Within the rheumatism network ADAPTHERA].
CONCLUSION: Screening of early arthritis patients for the presence of depressive symptoms is of essential importance. Patients seem to be at high risk of developing depressive symptoms especially at the beginning of the disease and when showing high disability and poor results on disease activity score (DAS28 and visual analog scale). PMID: 31016369 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - April 23, 2019 Category: Rheumatology Authors: Triantafyllias K, Leiß R, Dreher M, Schwarting A Tags: Z Rheumatol Source Type: research

Erratum zu: A  case of Hughes-Stovin syndrome (incomplete Behçet’s disease) with extensive arterial involvement.
Erratum zu: A case of Hughes-Stovin syndrome (incomplete Behçet’s disease) with extensive arterial involvement. Z Rheumatol. 2019 Apr 18;: Authors: Emad Y, Ragab Y, El-Marakbi A, Saad A, Ibrahim O, Abd-Elhalim A, El-Santawi H, Rasker JJ PMID: 31001652 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - April 18, 2019 Category: Rheumatology Authors: Emad Y, Ragab Y, El-Marakbi A, Saad A, Ibrahim O, Abd-Elhalim A, El-Santawi H, Rasker JJ Tags: Z Rheumatol Source Type: research

[Tight control-Demand for short term control of rheumatoid arthritis].
Abstract The prognosis of rheumatoid arthritis (RA) has been significantly improved in recent decades. This is mainly due to earlier detection, better diagnostics and new treatment options, such as the optimized use of classical disease-modifying antirheumatic drugs (DMARD) and biologicals. Other factors involved were earlier intervention, improved availability of information and analyses and certainly also standardization of care (e.g. guidelines). An additional important component is close monitoring of disease activity in order to be able to adapt the treatment in a timely manner and thus prevent damage. T...
Source: Zeitschrift fur Rheumatologie - April 18, 2019 Category: Rheumatology Authors: Schneider M, Burmester GR Tags: Z Rheumatol Source Type: research

[Peripheral nerve involvement in rheumatic diseases].
Abstract Peripheral neuropathies are probably an under-diagnosed complication of many rheumatic diseases. In some cases they take a mild clinical course, in others they cause severe impairment of patients' quality of life. A precise diagnosis and etiological classification are of major importance for successful treatment and prognosis of peripheral neuropathies. A detailed patient history and physical examination are the foundation of every diagnostic approach. Electrophysiological studies are obligatory when peripheral neuropathy is suspected, whereas nerve or nerve-muscle biopsies are indicated only in sele...
Source: Zeitschrift fur Rheumatologie - April 3, 2019 Category: Rheumatology Authors: Casteleyn V, Hahn K, Stenzel W, Siegert E Tags: Z Rheumatol Source Type: research

[Further evidence necessary for initial subcutaneous administration of MTX in the treatment of rheumatoid arthritis].
PMID: 30941503 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - April 2, 2019 Category: Rheumatology Authors: Harten P Tags: Z Rheumatol Source Type: research

[Why we recommend parenteral methotrexate for the treatment of rheumatoid arthritis: a response and overview of the literature].
“ PMID: 30941504 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - April 2, 2019 Category: Rheumatology Authors: Fiehn C, Autoren der S2e-Leitlinie „Therapie der rheumatoiden Arthritis mit krankheitsmodifizierenden Medikamenten“ Tags: Z Rheumatol Source Type: research

[Sj ögren's syndrome].
[Sjögren's syndrome]. Z Rheumatol. 2019 Apr 01;: Authors: Witte T Abstract The prevalence of primary Sjögren's syndrome (pSS) is between 1:100 and 1:1000 and it is therefore the most common connective tissue disease. Nevertheless, it can be difficult to diagnose pSS as the symptoms are frequently unspecific and diagnostic markers are lacking in many patients. In addition, only few controlled therapeutic studies of pSS have been carried out so that the optimal management is not yet clear. Meanwhile, outcome parameters to monitor clinical improvement have been developed and a large number...
Source: Zeitschrift fur Rheumatologie - April 1, 2019 Category: Rheumatology Authors: Witte T Tags: Z Rheumatol Source Type: research

[Hypereosinophilic syndrome and other rheumatic diseases with hypereosinophilia].
This article focuses on the hypereosinophilic syndromes. The potential differential diagnoses of Ig(immunoglobulin)G4-related disease, eosinophilic fasciitis and drug-induced vasculitis as well as eosinophilia-myalgia syndrome and toxic oil syndrome as historic drug-induced inflammatory rheumatic diseases are described and the clinical manifestations and treatment are summarized. PMID: 30937528 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - April 1, 2019 Category: Rheumatology Authors: Schirmer JH, Hoyer BF Tags: Z Rheumatol Source Type: research

[Treat to target-participation of the patient].
Abstract An increase in general health literacy and a targeted patient information are important prerequisites for coping with the chronic disease in people with inflammatory rheumatic diseases. The education programs of the Working Group of Regional Cooperative Rheumatism Centers in the German Society for Rheumatology (AGRZ), such as StruPI, the offers of the German Rheumatism League (Deutsche Rheuma-Liga) and other elements provide a framework for those affected and their relatives, in which a participative decision-making (PEF) on equal terms can be possible. The physician-patient communication changes in the s...
Source: Zeitschrift fur Rheumatologie - April 1, 2019 Category: Rheumatology Authors: Cattelaens K, Schewe S, Schuch F Tags: Z Rheumatol Source Type: research

[Comorbidities].
e A PMID: 30941588 [PubMed - in process] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - April 1, 2019 Category: Rheumatology Authors: Krüger K, Krause A Tags: Z Rheumatol Source Type: research

[Declaration of financial and non-financial interests in CME courses of Springer Medizin : Implementation of the regulation on the "Code on Continuing Medical Education" of the Medical Chamber North Rhine].
[Declaration of financial and non-financial interests in CME courses of Springer Medizin : Implementation of the regulation on the "Code on Continuing Medical Education" of the Medical Chamber North Rhine]. Z Rheumatol. 2019 Apr;78(3):213-214 Authors: Herrmann P, Griebenow R PMID: 30941589 [PubMed - in process] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - April 1, 2019 Category: Rheumatology Authors: Herrmann P, Griebenow R Tags: Z Rheumatol Source Type: research

Veranstaltungen der Rheumatologischen Fortbildungsakademie 2019 : Wir freuen uns auf Ihre Anmeldung über info@rheumaakademie.de.
Veranstaltungen der Rheumatologischen Fortbildungsakademie 2019 : Wir freuen uns auf Ihre Anmeldung über info@rheumaakademie.de. Z Rheumatol. 2019 Apr;78(3):295-298 Authors: PMID: 30941590 [PubMed - in process] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - April 1, 2019 Category: Rheumatology Tags: Z Rheumatol Source Type: research

RA: Therapie.
Authors: PMID: 30941591 [PubMed - in process] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - April 1, 2019 Category: Rheumatology Tags: Z Rheumatol Source Type: research

Mitteilungen der DRL.
Authors: PMID: 30941592 [PubMed - in process] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - April 1, 2019 Category: Rheumatology Tags: Z Rheumatol Source Type: research

[Osteoporosis-frequent comorbidity in patients with rheumatism].
Abstract Osteoporosis is one of the most frequent comorbidities in inflammatory rheumatic diseases. The immune system is substantially involved in the regulation of bone homeostasis and chronic inflammatory diseases influence this equilibrium at several levels. Besides the immunologically mediated inflammatory activity, immobility and glucocorticoid treatment are further risk factors for osteoporosis. Diagnostic and therapeutic recommendations are based on the current guidelines for osteoporosis of the Governing Body on Osteoporosis (DVO). Monitoring of the risk factors and bone mineral density testing is meaningf...
Source: Zeitschrift fur Rheumatologie - March 25, 2019 Category: Rheumatology Authors: Gaubitz M Tags: Z Rheumatol Source Type: research

[Pulmonary involvement in rheumatoid arthritis].
Abstract Pulmonary involvement in patients with rheumatoid arthritis, in particular interstitial lung diseases (RA-ILD) is of great clinical importance. Patients should be asked about symptoms of pulmonary involvement and the lungs should be clinically examined even during the diagnostic procedure and regularly during the course of the disease. Before initiation of a basic pharmacological treatment an X‑ray examination of thoracic organs is obligatory. In cases of conspicuous clinical or radiological findings, extended diagnostic procedures with lung function testing (body plethysmography with diffusion measurem...
Source: Zeitschrift fur Rheumatologie - March 18, 2019 Category: Rheumatology Authors: Krause A, Rubbert-Roth A Tags: Z Rheumatol Source Type: research

[Medical care situation of patients with ankylosing spondylitis and psoriatic arthritis in Germany : Medical care situation of patients with spondyloarthritis (SpA): ankylosing spondylitis (AS) and psoriatic arthritis (PsA) from the perspective of rheumatologists in private practice and hospitals in Germany-Results of the research project "SpA Loop-Life of Outpatients"].
CONCLUSION: The results of this research project reflect the current status of the medical care situation of AS and PsA patients in Germany. They provide information on which areas of the medical care situation can selectively be improved as well as on interesting aspects and points of discussion with respect to the patient population treated. PMID: 30874934 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - March 15, 2019 Category: Rheumatology Authors: Braun J, Schwarting A, Hammel L, Legeler C, Wimmer P, Färber L, Behrens F Tags: Z Rheumatol Source Type: research

A  case of Hughes-Stovin syndrome (incomplete Behçet's disease) with extensive arterial involvement : Unmasking the true face of a rare syndrome.
We describe a 35-year-old man with HSS showing classical features of the syndrome in the form of recurrent thrombophlebitis of the lower limb veins, pulmonary arterial aneurysms, and left lower limb ischemia with extensive arterial tree involvement. The patient presented with critical arterial ischemia in the left lower limb together with aortic and left common iliac artery thrombosis, occlusion of the left superficial femoral artery, and occlusion of both lower limb arteries. Urgent vascular surgeries were carried out for limb salvage. Shortly after, the patient started on pulse corticosteroid/cyclophosphamide therap...
Source: Zeitschrift fur Rheumatologie - March 14, 2019 Category: Rheumatology Authors: Emad Y, Ragab Y, El-Marakbi A, Saad A, Ibrahim O, Abd-Elhalim A, El-Santawi H, Rasker JJ Tags: Z Rheumatol Source Type: research

[Medical assistant-a profession in a state of flux].
Abstract New treatment strategies and treatment possibilities as well as undertreatment due to the lack of medical specialists especially in rheumatology, necessitate a qualified further training of rheumatological assistant personnel. The increasing independent work of medical and rheumatological assistants expected by physicians with respect to patient management and practice organization, necessitates an intensive cooperation between the two professional groups. The aim is to guarantee the competent treatment of chronically ill patients with rheumatism. Finally, this concept offers the chance of additional prof...
Source: Zeitschrift fur Rheumatologie - March 12, 2019 Category: Rheumatology Authors: Erstling U, Karberg K, Steffens-Korbanka P Tags: Z Rheumatol Source Type: research

[RABBIT-SpA: a  new disease register for axial spondyloarthritis and psoriatic arthritis].
CONCLUSION: The online register RABBIT-SpA is well-received by the participating rheumatological institutions. The electronic recording of patient data can be carried out in a reasonable time. Participation in the RABBIT-SpA is open to new rheumatological institutions at any time. PMID: 30874933 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - March 12, 2019 Category: Rheumatology Authors: Regierer AC, Weiß A, Baraliakos X, Zink A, Listing J, Strangfeld A Tags: Z Rheumatol Source Type: research

[Degenerative forefoot : Diagnostics and treatment].
ka J Abstract The hallux valgus deformity is the most common toe deformity of the forefoot and is often associated with a splayfoot. Malpositioning of the small toes may be isolated but are more common in other foot deformities. The understanding of the complex pathoanatomy of the foot is necessary for orthopedic treatment. Conservative treatment is reserved for the early stages. The indications for surgery should be based on clinical and radiographic findings. Countless surgical procedures are available and minimally invasive surgical techniques are also increasingly being used. PMID: 30848344 [PubMed -...
Source: Zeitschrift fur Rheumatologie - March 8, 2019 Category: Rheumatology Authors: Leiß F, Baier C, Schwarz T, Grifka J Tags: Z Rheumatol Source Type: research

[A 34-year-old patient with retropharyngeal tendinitis].
This article reports the case of a 34-year-old male patient presenting with neck pain, massive pressure pain of the neck muscles and limited cervical rotational mobility. Laboratory tests showed elevated levels for markers of inflammation. Computed tomography (CT) and magnetic resonance imaging (MRI) detected a retropharyngeal tendinitis of the longus cervicis muscle. This rare clinical entity is probably responsible for a high number of unreported cases. A CT scan, which can identify prevertebral edema and light calcification inferior to the ventral aspect of the second cervical vertebra, was previously the gold standard....
Source: Zeitschrift fur Rheumatologie - March 5, 2019 Category: Rheumatology Authors: Zipfel N, Schlüter A, Keyßer G, Schäfer C Tags: Z Rheumatol Source Type: research

[Improvement of prognosis by timely treatment : Requirement: initial presentation within 6 weeks].
Abstract Rheumatoid arthritis (RA) is one of the most frequent chronic inflammatory rheumatic diseases and when untreated leads to chronic tissue destruction and increased mortality. Due to innovative systemic treatment strategies established over the last 20-25 years, the prognosis has considerably improved in terms of disease and socioeconomic burdens, symptoms, long-term prognosis, ability to work and mortality; however, as a rule a prerequisite is long-term and continuous treatment. A medicinal cure of RA is still not in view. For many patients this means the long-term use of very expensive medicatio...
Source: Zeitschrift fur Rheumatologie - March 1, 2019 Category: Rheumatology Authors: Lorenz HM, Wendler J, Krause A Tags: Z Rheumatol Source Type: research

Osteoporosis therapy in patients with inflammatory rheumatic diseases and osteonecrosis of the jaw.
CONCLUSION: Inflammatory rheumatic diseases constitute a risk factor for MRONJ in patients treated with bisphosphonates for osteoporosis. Patients should be counseled accordingly and should be offered dental screening and regular dental check-ups. PMID: 30796524 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - February 22, 2019 Category: Rheumatology Authors: Schwaneck EC, Streit A, Krone M, Hartmann S, Müller-Richter U, Kübler AC, Gadeholt O, Schmalzing M, Tony HP, Brands RC Tags: Z Rheumatol Source Type: research

[Systematic literature search in PubMed : A short introduction].
tschall E Abstract In order to identify current (and relevant) evidence for a specific clinical question within the unmanageable amount of information available, solid skills in performing a systematic literature search are essential. An efficient approach is to search a biomedical database containing relevant literature citations of study reports. The best known database is MEDLINE, which is searchable for free via the PubMed interface. In this article, we explain step by step how to perform a systematic literature search via PubMed by means of an example research question in the field of opht...
Source: Zeitschrift fur Rheumatologie - February 12, 2019 Category: Rheumatology Authors: Blümle A, Lagrèze WA, Motschall E Tags: Z Rheumatol Source Type: research

Comparative efficacy and safety of 15 and 30  mg upadacitinib administered to patients with active rheumatoid arthritis: a Bayesian network meta-analysis of randomized controlled trials.
CONCLUSIONS: Upadacitinib 15 and 30 mg administration once daily in combination with MTX was the most efficacious intervention for active RA, with no significant risk for SAEs. PMID: 30725185 [PubMed - as supplied by publisher] (Source: Zeitschrift fur Rheumatologie)
Source: Zeitschrift fur Rheumatologie - February 6, 2019 Category: Rheumatology Authors: Song GG, Lee YH Tags: Z Rheumatol Source Type: research