Autoimmune rheumatic diseases associated with granulomatous mastitis
AbstractGranulomatous mastitis (GM) is a benign, inflammatory condition of the breast that mainly affects women of reproductive age. Although its pathogenesis remains unknown, previous studies revealed an association between autoimmune rheumatic diseases (ARDs) and GM in a subset of patients implicating immune-mediated mechanisms. The aim of this narrative review was to identify and describe the ARDs associated with GM to shed further light on disease pathogenesis. We conducted a comprehensive literature search of patients presenting with GM and coexisting ARDs using electronic databases. An association between GM and vari...
Source: Rheumatology International - March 1, 2023 Category: Rheumatology Source Type: research
Uncommon otological And Head & amp; Neck Manifestations of Wegener ’s Granulomatosis: A Rare Case Report
AbstractWegener ’s granulomatosis is a necrotising vasculitis affecting both arterioles and venules. The classical triad involves acute inflammation of upper airway along with inflammation of lower respiratory tract and renal involvement, however other organ system may also be affected. Our patient presented wit h severe unilateral earache, ear discharge, hearing loss and ipsilateral facial nerve palsy as the manifestations of the disease, which are rarely reported in medical literature1. (Source: Indian Journal of Otolaryngology and Head and Neck Surgery)
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - December 19, 2022 Category: ENT & OMF Source Type: research
Multiple Bullous and Ulcers as Cutaneous Manifestations of Wegener's Granulomatosis: A Rare Case Report
Clin Cosmet Investig Dermatol. 2022 Oct 7;15:2159-2164. doi: 10.2147/CCID.S385464. eCollection 2022.ABSTRACTBullous dermatoses is a heterogeneous group of blistering skin disorders that can either be inherited or acquired. Subepidermal blisters may result in ulceration and scarring following their rupture. Wegener's granulomatosis (WG) is a granulomatous necrotizing vasculitis affecting small- to medium-sized blood vessels. It is associated with anti-neutrophil cytoplasmic antibodies (ANCA) and can be manifested cutaneously as multiple bullous and ulcers. A case of WG was reported in an 18-year-old man presented with multi...
Source: Clinical, Cosmetic and Investigational Dermatology - October 14, 2022 Category: Dermatology Authors: Miranti Pangastuti Trustia Rizqandaru Oki Suwarsa Hartati Purbo Dharmadji Endang Sutedja Source Type: research
Scleritis as first manifestation of granulomatosis (Wegener's) with polyangiitis
J Fr Ophtalmol. 2022 Sep 30:S0181-5512(22)00286-8. doi: 10.1016/j.jfo.2022.04.024. Online ahead of print.NO ABSTRACTPMID:36192254 | DOI:10.1016/j.jfo.2022.04.024 (Source: Journal Francais d Ophtalmologie)
Source: Journal Francais d Ophtalmologie - October 3, 2022 Category: Opthalmology Authors: J S ánchez-Quirós B Burgos-Blasco D D íaz-Valle Source Type: research
Granulomatosis with polyangiitis in a patient with polydipsia, facial nerve paralysis, and severe otologic complaints: a case report and review of the literature
ConclusionGranulomatosis with polyangiitis is a highly variable disease, commonly involving the upper airways, but that may present with symptoms solely related to the pituitary gland. Clinicians should have a low threshold to investigate for granulomatosis with polyangiitis in patients with therapy-resistant otorrhea. Patients may present with a complex set of symptoms, and integrating different specialists when additional symptoms occur may lead to faster diagnosis. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - July 28, 2022 Category: General Medicine Source Type: research
ANCA Associated Vasculitis (AAV): A Review for Internists
Postgrad Med. 2022 Jul 13. doi: 10.1080/00325481.2022.2102368. Online ahead of print.ABSTRACTAnti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) compromise a rare group of necrotizing small to medium vessel vasculitides that constitute three distinct disorders: granulomatosis with polyangiitis (GPA) (formerly known as Wegener's granulomatosis), microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis (EGPA) (formerly known as Churg-Strauss syndrome).AAV is characterized by the usual presence of circulating autoantibodies to the neutrophil proteins leukocyte proteinase 3 (PR3-ANC...
Source: Postgraduate Medicine - July 14, 2022 Category: Internal Medicine Authors: Kinanah Yaseen Brian F Mandell Source Type: research
Endoscopic Coronary Catheter Dacryoplasty for Failed DCR in Wegener's Granulomatosis
Ocul Immunol Inflamm. 2022 Feb 3:1-2. doi: 10.1080/09273948.2022.2032200. Online ahead of print.NO ABSTRACTPMID:35113738 | DOI:10.1080/09273948.2022.2032200 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - February 3, 2022 Category: Allergy & Immunology Authors: Rafal Nowak Mohammad Javed Ali Source Type: research
