Wegener's Granulomatosis Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

ANCA-Associated Vasculitic Neuropathies: A Review
AbstractAnti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is a systemic disorder that frequently affects the peripheral nervous system and consists of three distinct conditions: microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA, previously Wegener ’s granulomatosis), and eosinophilic granulomatosis with polyangiitis (EGPA, previously Churg-Strauss syndrome). The neuropathic features associated with this condition usually include mononeuritis multiplex, which reflects the locality of lesions. Findings suggestive of vasculitis are usually fou nd in the epineurium and occur diffusely thro...
Source: Neurology and Therapy - January 19, 2022 Category: Neurology Source Type: research

Proteinase 3 associated with Wegener's Granulomatosis
This article is protected by copyright. All rights reserved.PMID:34957648 | DOI:10.1002/cbin.11757 (Source: Cell Biology International)
Source: Cell Biology International - December 27, 2021 Category: Cytology Authors: Wolfgang H Goldmann Source Type: research

Proteinase 3 associated with Wegener's granulomatosis
Cell Biol Int. 2021 Dec 26. doi: 10.1002/cbin.11757. Online ahead of print.ABSTRACTWegener's granulomatosis (WG) is a form of systemic vasculitis characterized by granulomatous inflammation of the upper and lower airways, vasculitis, and necrotizing glomerulonephritis. It is strongly associated with anti-neutrophil cytoplasmic antibodies against proteinase 3 (PR3-ANCAs). Various in vitro observations provided strong evidence that autoimmune PR3-ANCAs are directly involved in glomerular and vascular inflammation. However, little is known about the pathogenic significance of PR3-ANCAs in vivo. Therefore, the generation of an...
Source: Cell Biology International - December 27, 2021 Category: Cytology Authors: Wolfgang H Goldmann Source Type: research

A Case Report and Literature Review of Pulmonary Wegener' Granulomatosis
Wegener ’ granulomatosis is an autoimmune diseases, often involving the lung and kidney, has a high mortality rate in nontreatment patients. The low incidence and nonspecific features, often lead to misdiagnosis and delayed treatment. This paper reported the diagnosis and treatment of a 55-year-old female patient with primary Wegener ' granuloma of the lung diagnosed by percutaneous lung biopsy of pulmonary nodules, and reviews the relevant literature.   DOI: 10.3779/j.issn.1009-3419.2021.101.47 (Source: Chinese Journal of Lung Cancer)
Source: Chinese Journal of Lung Cancer - December 20, 2021 Category: Cancer & Oncology Source Type: research

Management of Severe Oral Inflammatory Conditions in Dogs and Cats
This article discusses a brief review of important points in the oral diagnosis and management of main canine (canine chronic ulcerative stomatitis (CCUS), eosinophilic stomatitis, and Wegener ’s granulomatosis (WG)) and feline diseases (feline gingivostomatitis/caudal stomatitis, oral eosinophilic lesions, pyogenic granuloma, and autoimmune diseases with oral manifestations), and—whereby possible—information about the current understanding of disease pathogenesis and treatment is o ffered. (Source: Veterinary Clinics of North America: Small Animal Practice)
Source: Veterinary Clinics of North America: Small Animal Practice - November 25, 2021 Category: Veterinary Research Authors: Jamie G. Anderson, Philippe Hennet Source Type: research

A case of wegener's granulomatosis presenting with gastrointestinal bleeding
No abstract available (Source: Gastroenterology Nursing)
Source: Gastroenterology Nursing - November 1, 2021 Category: Nursing Tags: Departments Source Type: research

Epidemiology and genetics of granulomatosis with polyangiitis
AbstractGranulomatosis with polyangiitis (GPA) previously known as Wegener ’s granulomatosis (WG) is a rare rheumatic disease affecting subjects of all ages. Prevalence and incidence of this systemic disease greatly varies across different ethnic groups. GPA is the commonest form of ANCA-associated vasculitis (AAV) with PR3 positivity among 85–95% of the cases. Scient ific investigations of GPA is warranted because its severity, clinical heterogeneity, fast disease manifestation and end-organ damage. The etiology of GPA is still unknown. Major role of HLA and non-HLA genes with immune functions were identified, howev...
Source: Rheumatology International - October 31, 2021 Category: Rheumatology Source Type: research

Clinical features and outcomes of anti-neutrophil cytoplasmic autoantibody-associated vasculitis in Chinese childhood-onset patients
This study is to determine the clinical features and outcomes of childhood-onset AAV. A retrospective study was performed on patients who were diagnosed with AAV before 18 years old in Xiangya Hospital. Their medical records were analyzed by retrospective review. Sixteen patients were diagnosed with AAV before 18 years old in the past 9 years, with an average age of 13.3 ± 3.3 years and 13 of them were female. There were 15 patients with microscopic polyangi itis (MPA) and 1 with Wegener’s granulomatosis. The interval between onset of disease and diagnosis of AAV was 2 (1.5–3) months. Most patients (15/16, 93...
Source: Clinical and Experimental Medicine - September 22, 2021 Category: Research Source Type: research