Nonsteroidal anti-inflammatory drugs before endoscopic ultrasound guided tissue acquisition to reduce the incidence of post procedural pancreatitis
World J Gastroenterol. 2024 Feb 28;30(8):811-816. doi: 10.3748/wjg.v30.i8.811.ABSTRACTEndoscopic ultrasound (EUS) with fine needle aspiration or fine needle biopsy is the gold standard for sampling tissue to diagnose pancreatic cancer and autoimmune pancreatitis or to analyze cyst fluid. The most common reported adverse event of fine needle aspiration and/or fine needle biopsy is acute pancreatitis, which is likely induced by the same pathophysiological mechanisms as after endoscopic retrograde cholangiopancreatography (ERCP). According to the current European Society of Gastrointestinal Endoscopy guideline, nonsteroidal a...
Source: World Journal of Gastroenterology - March 22, 2024 Category: Gastroenterology Authors: Mike de Jong Foke van Delft Christine Roozen Erwin-Jan van Geenen Tanya Bisseling Peter Siersema Marco Bruno Source Type: research

Nonsteroidal anti-inflammatory drugs before endoscopic ultrasound guided tissue acquisition to reduce the incidence of post procedural pancreatitis
World J Gastroenterol. 2024 Feb 28;30(8):811-816. doi: 10.3748/wjg.v30.i8.811.ABSTRACTEndoscopic ultrasound (EUS) with fine needle aspiration or fine needle biopsy is the gold standard for sampling tissue to diagnose pancreatic cancer and autoimmune pancreatitis or to analyze cyst fluid. The most common reported adverse event of fine needle aspiration and/or fine needle biopsy is acute pancreatitis, which is likely induced by the same pathophysiological mechanisms as after endoscopic retrograde cholangiopancreatography (ERCP). According to the current European Society of Gastrointestinal Endoscopy guideline, nonsteroidal a...
Source: World Journal of Gastroenterology : WJG - March 22, 2024 Category: Gastroenterology Authors: Mike de Jong Foke van Delft Christine Roozen Erwin-Jan van Geenen Tanya Bisseling Peter Siersema Marco Bruno Source Type: research

Nonsteroidal anti-inflammatory drugs before endoscopic ultrasound guided tissue acquisition to reduce the incidence of post procedural pancreatitis
World J Gastroenterol. 2024 Feb 28;30(8):811-816. doi: 10.3748/wjg.v30.i8.811.ABSTRACTEndoscopic ultrasound (EUS) with fine needle aspiration or fine needle biopsy is the gold standard for sampling tissue to diagnose pancreatic cancer and autoimmune pancreatitis or to analyze cyst fluid. The most common reported adverse event of fine needle aspiration and/or fine needle biopsy is acute pancreatitis, which is likely induced by the same pathophysiological mechanisms as after endoscopic retrograde cholangiopancreatography (ERCP). According to the current European Society of Gastrointestinal Endoscopy guideline, nonsteroidal a...
Source: World Journal of Gastroenterology - March 22, 2024 Category: Gastroenterology Authors: Mike de Jong Foke van Delft Christine Roozen Erwin-Jan van Geenen Tanya Bisseling Peter Siersema Marco Bruno Source Type: research

Nonsteroidal anti-inflammatory drugs before endoscopic ultrasound guided tissue acquisition to reduce the incidence of post procedural pancreatitis
World J Gastroenterol. 2024 Feb 28;30(8):811-816. doi: 10.3748/wjg.v30.i8.811.ABSTRACTEndoscopic ultrasound (EUS) with fine needle aspiration or fine needle biopsy is the gold standard for sampling tissue to diagnose pancreatic cancer and autoimmune pancreatitis or to analyze cyst fluid. The most common reported adverse event of fine needle aspiration and/or fine needle biopsy is acute pancreatitis, which is likely induced by the same pathophysiological mechanisms as after endoscopic retrograde cholangiopancreatography (ERCP). According to the current European Society of Gastrointestinal Endoscopy guideline, nonsteroidal a...
Source: World Journal of Gastroenterology : WJG - March 22, 2024 Category: Gastroenterology Authors: Mike de Jong Foke van Delft Christine Roozen Erwin-Jan van Geenen Tanya Bisseling Peter Siersema Marco Bruno Source Type: research

Nonsteroidal anti-inflammatory drugs before endoscopic ultrasound guided tissue acquisition to reduce the incidence of post procedural pancreatitis
World J Gastroenterol. 2024 Feb 28;30(8):811-816. doi: 10.3748/wjg.v30.i8.811.ABSTRACTEndoscopic ultrasound (EUS) with fine needle aspiration or fine needle biopsy is the gold standard for sampling tissue to diagnose pancreatic cancer and autoimmune pancreatitis or to analyze cyst fluid. The most common reported adverse event of fine needle aspiration and/or fine needle biopsy is acute pancreatitis, which is likely induced by the same pathophysiological mechanisms as after endoscopic retrograde cholangiopancreatography (ERCP). According to the current European Society of Gastrointestinal Endoscopy guideline, nonsteroidal a...
Source: World Journal of Gastroenterology - March 22, 2024 Category: Gastroenterology Authors: Mike de Jong Foke van Delft Christine Roozen Erwin-Jan van Geenen Tanya Bisseling Peter Siersema Marco Bruno Source Type: research

Nonsteroidal anti-inflammatory drugs before endoscopic ultrasound guided tissue acquisition to reduce the incidence of post procedural pancreatitis
World J Gastroenterol. 2024 Feb 28;30(8):811-816. doi: 10.3748/wjg.v30.i8.811.ABSTRACTEndoscopic ultrasound (EUS) with fine needle aspiration or fine needle biopsy is the gold standard for sampling tissue to diagnose pancreatic cancer and autoimmune pancreatitis or to analyze cyst fluid. The most common reported adverse event of fine needle aspiration and/or fine needle biopsy is acute pancreatitis, which is likely induced by the same pathophysiological mechanisms as after endoscopic retrograde cholangiopancreatography (ERCP). According to the current European Society of Gastrointestinal Endoscopy guideline, nonsteroidal a...
Source: World Journal of Gastroenterology : WJG - March 22, 2024 Category: Gastroenterology Authors: Mike de Jong Foke van Delft Christine Roozen Erwin-Jan van Geenen Tanya Bisseling Peter Siersema Marco Bruno Source Type: research

Nonsteroidal anti-inflammatory drugs before endoscopic ultrasound guided tissue acquisition to reduce the incidence of post procedural pancreatitis
World J Gastroenterol. 2024 Feb 28;30(8):811-816. doi: 10.3748/wjg.v30.i8.811.ABSTRACTEndoscopic ultrasound (EUS) with fine needle aspiration or fine needle biopsy is the gold standard for sampling tissue to diagnose pancreatic cancer and autoimmune pancreatitis or to analyze cyst fluid. The most common reported adverse event of fine needle aspiration and/or fine needle biopsy is acute pancreatitis, which is likely induced by the same pathophysiological mechanisms as after endoscopic retrograde cholangiopancreatography (ERCP). According to the current European Society of Gastrointestinal Endoscopy guideline, nonsteroidal a...
Source: World Journal of Gastroenterology - March 22, 2024 Category: Gastroenterology Authors: Mike de Jong Foke van Delft Christine Roozen Erwin-Jan van Geenen Tanya Bisseling Peter Siersema Marco Bruno Source Type: research

Characterization of Diclofenac-induced Renal Damage in Normotensive and Hypertensive Rats: A Comparative Analysis
Conclusions The data presented herein demonstrated that diclofenac induces renal damage and impaired renal function in both NTR and SHR, but those effects are exacerbated in SHR, as seen by the histological changes and electrolytes balance disturbance, therefore, reinforcing that diclofenac may increase the risks of cardiovascular events in hypertensive patients. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Drug Research)
Source: Drug Research - March 19, 2024 Category: Drugs & Pharmacology Authors: Boeing, Thaise Lima, Alana Bittencourt F. Busana, Maria Eduarda Mariano, Lu ísa Nathália Bolda da Silva, Luisa Mota Silva, Rita de C ássia Vilhena da de Souza, Priscila Tags: Original Article Source Type: research

Systematic review of randomized controlled trials of topicals for actinic keratosis field therapy
This study aims to systematically review randomized controlled trials on topical treatments for actinic keratosis field cancerization, following the PRISMA guidelines. Clinical recommendations were based on the Oxford Centre for Evidence-Based Medicine. We identified 20 original randomized controlled trials for topical cutaneous field therapy. 0.5% 5-Fluorouracil/salicylic acid and 0.5% 5-fluorouracil received a clinical recommendation grade of A, while diclofenac sodium received a clinical recommendation grade of B. Calcipotriol/5-fluorouracil, Imiquimod, sunscreen combination therapies, and tirbanibulin received a recomm...
Source: Cell Research - March 18, 2024 Category: Cytology Authors: Paras Patel Jennifer Wang David Bitterman Jessica Mineroff Evan Austin Jared Jagdeo Source Type: research

Systematic review of randomized controlled trials of topicals for actinic keratosis field therapy
This study aims to systematically review randomized controlled trials on topical treatments for actinic keratosis field cancerization, following the PRISMA guidelines. Clinical recommendations were based on the Oxford Centre for Evidence-Based Medicine. We identified 20 original randomized controlled trials for topical cutaneous field therapy. 0.5% 5-Fluorouracil/salicylic acid and 0.5% 5-fluorouracil received a clinical recommendation grade of A, while diclofenac sodium received a clinical recommendation grade of B. Calcipotriol/5-fluorouracil, Imiquimod, sunscreen combination therapies, and tirbanibulin received a recomm...
Source: Archives of Dermatological Research - March 18, 2024 Category: Dermatology Source Type: research

A Combination of Pharmacophore Generation, Ligand-based Virtual Screening, Atom-based 3D-QSAR, and Molecular Docking Studies on Febuxostat-based Amides Analogues as Anti-inflammatory Agents
CONCLUSION: The virtual screen compounds have shown similar docking interaction with amino acid residues as shown by standard diclofenac sodium drugs. Therefore, the findings in the present study can be explored in the development of potent anti-inflammatory agents.PMID:38485685 | DOI:10.2174/0115701638281229240226101906 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - March 14, 2024 Category: Drugs & Pharmacology Authors: Trupti Chitre Aniket Bhatambrekar Purvaj Hirode Shubhangi Thorat Sayli G Hajare Dinesh Garud Sakshi Jagdale Kalyani Asgaonkar Source Type: research

A Combination of Pharmacophore Generation, Ligand-based Virtual Screening, Atom-based 3D-QSAR, and Molecular Docking Studies on Febuxostat-based Amides Analogues as Anti-inflammatory Agents
CONCLUSION: The virtual screen compounds have shown similar docking interaction with amino acid residues as shown by standard diclofenac sodium drugs. Therefore, the findings in the present study can be explored in the development of potent anti-inflammatory agents.PMID:38485685 | DOI:10.2174/0115701638281229240226101906 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - March 14, 2024 Category: Drugs & Pharmacology Authors: Trupti Chitre Aniket Bhatambrekar Purvaj Hirode Shubhangi Thorat Sayli G Hajare Dinesh Garud Sakshi Jagdale Kalyani Asgaonkar Source Type: research

A Combination of Pharmacophore Generation, Ligand-based Virtual Screening, Atom-based 3D-QSAR, and Molecular Docking Studies on Febuxostat-based Amides Analogues as Anti-inflammatory Agents
CONCLUSION: The virtual screen compounds have shown similar docking interaction with amino acid residues as shown by standard diclofenac sodium drugs. Therefore, the findings in the present study can be explored in the development of potent anti-inflammatory agents.PMID:38485685 | DOI:10.2174/0115701638281229240226101906 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - March 14, 2024 Category: Drugs & Pharmacology Authors: Trupti Chitre Aniket Bhatambrekar Purvaj Hirode Shubhangi Thorat Sayli G Hajare Dinesh Garud Sakshi Jagdale Kalyani Asgaonkar Source Type: research

A Combination of Pharmacophore Generation, Ligand-based Virtual Screening, Atom-based 3D-QSAR, and Molecular Docking Studies on Febuxostat-based Amides Analogues as Anti-inflammatory Agents
CONCLUSION: The virtual screen compounds have shown similar docking interaction with amino acid residues as shown by standard diclofenac sodium drugs. Therefore, the findings in the present study can be explored in the development of potent anti-inflammatory agents.PMID:38485685 | DOI:10.2174/0115701638281229240226101906 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - March 14, 2024 Category: Drugs & Pharmacology Authors: Trupti Chitre Aniket Bhatambrekar Purvaj Hirode Shubhangi Thorat Sayli G Hajare Dinesh Garud Sakshi Jagdale Kalyani Asgaonkar Source Type: research