Toxicological effects of diclofenac on signal crayfish (Pacifastacus leniusculus) as related to weakly acidic and basic water pH
This study aimed to investigate the effects of diclofenac (DCF) on the antioxidant defence system and neurotoxicity biomarkers in signal crayfish (Pacifastacus leniusculus) under weakly acidic and basic conditions. Crayfish were exposed to 200 µg/L of DCF at pH 6 and 8 for 96 h and subsequently underwent the depuration phase for 96 h. Gills, hepatopancreas, and muscle were sampled after the exposure and depuration phases to assess the toxicological biomarker responses of DCF in crayfish by evaluating lipid peroxidation (LPO) levels, activities of antioxidant enzymes and acetylcholinesterase. After the exposure phase, the ...
Source: Aquatic Toxicology - November 30, 2023 Category: Toxicology Authors: Tuyen Van Nguyen Adam Bo řík Jaylen L Sims Anton ín Kouba Vladim ír Žlábek Anna Koubov á Source Type: research

A magnetically induced self-assembly of Ru@Fe < sub > 3 < /sub > O < sub > 4 < /sub > /rGO cathode for diclofenac degradation in electro-Fenton process
This study provides new insights into the magnetically assembled electrode of Ru@Fe3O4/rGO and displays a new practical application prospect of the materials for high-efficient removal and degradation of DCF from wastewater.PMID:38036212 | DOI:10.1016/j.envres.2023.117781 (Source: Environmental Research)
Source: Environmental Research - November 30, 2023 Category: Environmental Health Authors: Bing Qiu Xiaolan Zhou Weimin Li Houjuan Zhu Long Yu Chao Yuan Rongni Dou Mingtai Sun Suhua Wang Source Type: research

Correction: Investigations on Compaction Behavior of Kollidon ®SR-Based Multi-component Directly Compressed Tablets for Preparation of Controlled Release Diclofenac Sodium
AAPS PharmSciTech. 2023 Nov 30;24(8):249. doi: 10.1208/s12249-023-02707-4.NO ABSTRACTPMID:38036726 | DOI:10.1208/s12249-023-02707-4 (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - November 30, 2023 Category: Drugs & Pharmacology Authors: Wasfy M Obeidat Ishraq K Lahlouh Shadi F Gharaibeh Source Type: research

Toxicological effects of diclofenac on signal crayfish (Pacifastacus leniusculus) as related to weakly acidic and basic water pH
This study aimed to investigate the effects of diclofenac (DCF) on the antioxidant defence system and neurotoxicity biomarkers in signal crayfish (Pacifastacus leniusculus) under weakly acidic and basic conditions. Crayfish were exposed to 200 µg/L of DCF at pH 6 and 8 for 96 h and subsequently underwent the depuration phase for 96 h. Gills, hepatopancreas, and muscle were sampled after the exposure and depuration phases to assess the toxicological biomarker responses of DCF in crayfish by evaluating lipid peroxidation (LPO) levels, activities of antioxidant enzymes and acetylcholinesterase. After the exposure phase, the ...
Source: Aquatic Toxicology - November 30, 2023 Category: Toxicology Authors: Tuyen Van Nguyen Adam Bo řík Jaylen L Sims Anton ín Kouba Vladim ír Žlábek Anna Koubov á Source Type: research

A magnetically induced self-assembly of Ru@Fe < sub > 3 < /sub > O < sub > 4 < /sub > /rGO cathode for diclofenac degradation in electro-Fenton process
This study provides new insights into the magnetically assembled electrode of Ru@Fe3O4/rGO and displays a new practical application prospect of the materials for high-efficient removal and degradation of DCF from wastewater.PMID:38036212 | DOI:10.1016/j.envres.2023.117781 (Source: Environmental Research)
Source: Environmental Research - November 30, 2023 Category: Environmental Health Authors: Bing Qiu Xiaolan Zhou Weimin Li Houjuan Zhu Long Yu Chao Yuan Rongni Dou Mingtai Sun Suhua Wang Source Type: research

Correction: Investigations on Compaction Behavior of Kollidon ®SR-Based Multi-component Directly Compressed Tablets for Preparation of Controlled Release Diclofenac Sodium
AAPS PharmSciTech. 2023 Nov 30;24(8):249. doi: 10.1208/s12249-023-02707-4.NO ABSTRACTPMID:38036726 | DOI:10.1208/s12249-023-02707-4 (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - November 30, 2023 Category: Drugs & Pharmacology Authors: Wasfy M Obeidat Ishraq K Lahlouh Shadi F Gharaibeh Source Type: research

Correction: Investigations on Compaction Behavior of Kollidon ®SR-Based Multi-component Directly Compressed Tablets for Preparation of Controlled Release Diclofenac Sodium
AAPS PharmSciTech. 2023 Nov 30;24(8):249. doi: 10.1208/s12249-023-02707-4.NO ABSTRACTPMID:38036726 | DOI:10.1208/s12249-023-02707-4 (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - November 30, 2023 Category: Drugs & Pharmacology Authors: Wasfy M Obeidat Ishraq K Lahlouh Shadi F Gharaibeh Source Type: research

Correction: Investigations on Compaction Behavior of Kollidon ®SR-Based Multi-component Directly Compressed Tablets for Preparation of Controlled Release Diclofenac Sodium
AAPS PharmSciTech. 2023 Nov 30;24(8):249. doi: 10.1208/s12249-023-02707-4.NO ABSTRACTPMID:38036726 | DOI:10.1208/s12249-023-02707-4 (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - November 30, 2023 Category: Drugs & Pharmacology Authors: Wasfy M Obeidat Ishraq K Lahlouh Shadi F Gharaibeh Source Type: research

Analysis and risk assessment of pharmaceutical residues in fish from three water bodies in Ghana
J Water Health. 2023 Nov;21(11):1703-1715. doi: 10.2166/wh.2023.208.ABSTRACTIllegal mining has overshadowed pharmaceutical pollution even though exposure to pharmaceutical waste is high. Consumption of fish potentially polluted with pharmaceuticals from the rivers continues with little concern or potential threat it poses. In the present study, the residues of one antibiotic (Chloramphenicol), five hormones (progesterone, 17-beta Estradiol, Estrone, 17a-Ethynylestradiol, and one), three environmental contaminants (4-para-nonylphenol, 4-tert-octylphenol, and Bisphenol A), one barbiturate (Primidone) and one analgesic (Diclo...
Source: Journal of Water and Health - November 29, 2023 Category: Environmental Health Authors: Albert Ebo Duncan Christian Adokoh Martha Osei-Marfo Samuel Barnie Aboagye George Sakyi Josephe Adjei Source Type: research

Ceftriaxone Use Evaluation in Western Zone Tigray Hospitals, Ethiopia: A Retrospective Cross-Sectional Study
CONCLUSION: The appropriateness of ceftriaxone use in Kahsay Abera and Mearg hospitals was 247 (61.8%) and 252 (63%), respectively, in which about one-third of patients' charts were not compliant with the standard treatment guidelines of Ethiopia for general hospitals. In Kahsay Abera and Mearg hospitals, the empiric use of ceftriaxone was 262 (65.5%) and 375 (93.8%), respectively.PMID:38027045 | PMC:PMC10661873 | DOI:10.1155/2023/7688896 (Source: Biomed Res)
Source: Biomed Res - November 29, 2023 Category: Research Authors: Tewodros Shegute Mulugeta Hiruy Haftom Hadush Leake Gebremeskel Source Type: research

Analysis and risk assessment of pharmaceutical residues in fish from three water bodies in Ghana
J Water Health. 2023 Nov;21(11):1703-1715. doi: 10.2166/wh.2023.208.ABSTRACTIllegal mining has overshadowed pharmaceutical pollution even though exposure to pharmaceutical waste is high. Consumption of fish potentially polluted with pharmaceuticals from the rivers continues with little concern or potential threat it poses. In the present study, the residues of one antibiotic (Chloramphenicol), five hormones (progesterone, 17-beta Estradiol, Estrone, 17a-Ethynylestradiol, and one), three environmental contaminants (4-para-nonylphenol, 4-tert-octylphenol, and Bisphenol A), one barbiturate (Primidone) and one analgesic (Diclo...
Source: Journal of Water and Health - November 29, 2023 Category: Environmental Health Authors: Albert Ebo Duncan Christian Adokoh Martha Osei-Marfo Samuel Barnie Aboagye George Sakyi Josephe Adjei Source Type: research