Stevioside mitigates lead toxicity in thinlip mullet juveniles: Impacts on growth, metabolism, and immune function
In conclusion, stevioside, especially at 450 mg, positively impacted growth, biochemical parameters, antioxidant activity, immune response, and gene expression in L. ramada exposed to lead, suggesting its potential to mitigate lead toxicity in aquaculture. Additional research is warranted to investigate the long-term impacts of stevioside supplementation and its prospective implementation in aquaculture.PMID:38631122 | DOI:10.1016/j.aquatox.2024.106910 (Source: Aquatic Toxicology)
Source: Aquatic Toxicology - April 17, 2024 Category: Toxicology Authors: Akram Ismael Shehata Shimaa A Shahin Ayaat M Elmaghraby Mayada Alhoshy Mohamed M Toutou Ali A Soliman Asem A Amer Yusuf Jibril Habib Mahmoud S Gewaily Islam I Teiba Mohammed F El Basuini Source Type: research

Sex-specific impacts of thimerosal on the behaviors and brain monoaminergic systems in zebrafish (Danio rerio)
In this study, zebrafish were exposed to THI for 7 days, and variations in their behavioral traits, brain monoaminergic neurotransmitter contents, and related gene expression were investigated. After the 7-day exposure, THI reduced locomotor activity and thigmotaxis in males but not females. Exposure to THI increased the social interaction between females but decreased that between males. The THI exposure also significantly reduced the serotonin (5-HT), 5-hydroxyindoleacetic acid, dopamine (DA), and 3,4-dihydroxyphenylacetic acid contents in the brain of males, but only significantly decreased the DA content in females. Co...
Source: Aquatic Toxicology - April 14, 2024 Category: Toxicology Authors: Xuchun Qiu Zhen Su Jiarui Gao Yiming Cui Kejun Dong Kun Chen Ru-Jin Zhao Songmei Wang Tao Wu Yanhong Shi Source Type: research

Chronic toxic effects of erythromycin and its photodegradation products on microalgae Chlorella pyrenoidosa
This study initially focused on examining the acute effects of erythromycin (ERY), then explored the chronic impacts of ERY PDPs on Chlorella pyrenoidosa. ERY of 4.0 - 32 mg/L ERY notably inhibited the cell growth and chlorophyll synthesis. The determined 96 h median effective concentration of ERY to C. pyrenoidosa was 11.78 mg/L. Higher concentrations of ERY induced more serious oxidative damage, antioxidant enzymes alleviated the oxidative stress. 6 PDPs (PDP749, PDP747, PDP719, PDP715, PDP701 and PDP557) were identified in the photodegradation process of ERY. The predicted combined toxicity of PDPs increased in the firs...
Source: Aquatic Toxicology - April 14, 2024 Category: Toxicology Authors: Jiping Li Wei Li Naisen Liu Chenggong Du Source Type: research

Sex-specific impacts of thimerosal on the behaviors and brain monoaminergic systems in zebrafish (Danio rerio)
In this study, zebrafish were exposed to THI for 7 days, and variations in their behavioral traits, brain monoaminergic neurotransmitter contents, and related gene expression were investigated. After the 7-day exposure, THI reduced locomotor activity and thigmotaxis in males but not females. Exposure to THI increased the social interaction between females but decreased that between males. The THI exposure also significantly reduced the serotonin (5-HT), 5-hydroxyindoleacetic acid, dopamine (DA), and 3,4-dihydroxyphenylacetic acid contents in the brain of males, but only significantly decreased the DA content in females. Co...
Source: Aquatic Toxicology - April 14, 2024 Category: Toxicology Authors: Xuchun Qiu Zhen Su Jiarui Gao Yiming Cui Kejun Dong Kun Chen Ru-Jin Zhao Songmei Wang Tao Wu Yanhong Shi Source Type: research

Chronic toxic effects of erythromycin and its photodegradation products on microalgae Chlorella pyrenoidosa
This study initially focused on examining the acute effects of erythromycin (ERY), then explored the chronic impacts of ERY PDPs on Chlorella pyrenoidosa. ERY of 4.0 - 32 mg/L ERY notably inhibited the cell growth and chlorophyll synthesis. The determined 96 h median effective concentration of ERY to C. pyrenoidosa was 11.78 mg/L. Higher concentrations of ERY induced more serious oxidative damage, antioxidant enzymes alleviated the oxidative stress. 6 PDPs (PDP749, PDP747, PDP719, PDP715, PDP701 and PDP557) were identified in the photodegradation process of ERY. The predicted combined toxicity of PDPs increased in the firs...
Source: Aquatic Toxicology - April 14, 2024 Category: Toxicology Authors: Jiping Li Wei Li Naisen Liu Chenggong Du Source Type: research

Metabolomic changes following GenX and PFBS exposure in developing zebrafish
In this study, larval zebrafish were used to investigate the toxicity of early-life exposure to GenX or PFBS. Zebrafish were chronically exposed from 4 h post-fertilization (hpf) to 6 days post-fertilization (dpf) to 150 µM GenX or 95.0 µM PFBS. Ultra-high-performance liquid chromatography paired with high-resolution mass spectrometry was used to quantify uptake of GenX and PFBS into zebrafish larvae and perform targeted and untargeted metabolomics. Our results indicate that PFBS was 20.4 % more readily absorbed into the zebrafish larvae compared to GenX. Additionally, PFBS exposure significantly altered 13 targeted meta...
Source: Aquatic Toxicology - April 12, 2024 Category: Toxicology Authors: Fiona Dunn Shannon E Paquette Kurt D Pennell Jessica S Plavicki Katherine E Manz Source Type: research

Effects of clarithromycin exposure on the growth of Microcystis aeruginosa and the production of algal dissolved organic matter
Aquat Toxicol. 2024 Apr 6;271:106918. doi: 10.1016/j.aquatox.2024.106918. Online ahead of print.ABSTRACTAntibiotics are commonly found in the aquatic environment, which can affect microbial community compositions and activities, and even have potential adverse impacts on human and ecosystem health. The current understanding of the effects of antibiotics on microalgae growth and algal dissolved organic matter (DOM) remains indistinct. To understand the toxic effects of antibiotics on the microalgae, Microcystis aeruginosa was exposed to clarithromycin (CLA) in this study. Cell density determination, chlorophyll content dete...
Source: Aquatic Toxicology - April 10, 2024 Category: Toxicology Authors: Chong-Miao Zhang Qing Zhou Yong-Qiang Li Jie Li Source Type: research

Effects of clarithromycin exposure on the growth of Microcystis aeruginosa and the production of algal dissolved organic matter
Aquat Toxicol. 2024 Apr 6;271:106918. doi: 10.1016/j.aquatox.2024.106918. Online ahead of print.ABSTRACTAntibiotics are commonly found in the aquatic environment, which can affect microbial community compositions and activities, and even have potential adverse impacts on human and ecosystem health. The current understanding of the effects of antibiotics on microalgae growth and algal dissolved organic matter (DOM) remains indistinct. To understand the toxic effects of antibiotics on the microalgae, Microcystis aeruginosa was exposed to clarithromycin (CLA) in this study. Cell density determination, chlorophyll content dete...
Source: Aquatic Toxicology - April 10, 2024 Category: Toxicology Authors: Chong-Miao Zhang Qing Zhou Yong-Qiang Li Jie Li Source Type: research

Effects of clarithromycin exposure on the growth of Microcystis aeruginosa and the production of algal dissolved organic matter
Aquat Toxicol. 2024 Apr 6;271:106918. doi: 10.1016/j.aquatox.2024.106918. Online ahead of print.ABSTRACTAntibiotics are commonly found in the aquatic environment, which can affect microbial community compositions and activities, and even have potential adverse impacts on human and ecosystem health. The current understanding of the effects of antibiotics on microalgae growth and algal dissolved organic matter (DOM) remains indistinct. To understand the toxic effects of antibiotics on the microalgae, Microcystis aeruginosa was exposed to clarithromycin (CLA) in this study. Cell density determination, chlorophyll content dete...
Source: Aquatic Toxicology - April 10, 2024 Category: Toxicology Authors: Chong-Miao Zhang Qing Zhou Yong-Qiang Li Jie Li Source Type: research

Atorvastatin causes developmental and behavioral toxicity in yellowstripe goby (Mugilogobius chulae) embryos/larvae via disrupting lipid metabolism and autophagy processes
Aquat Toxicol. 2024 Apr 6;271:106909. doi: 10.1016/j.aquatox.2024.106909. Online ahead of print.ABSTRACTAtorvastatin (ATV) is one of the most commonly prescribed lipid-lowering drugs detected frequently in the environment due to its high use and low degradation rate. However, the toxic effects of residual ATV in the aquatic environment on non-target organisms and its toxic mechanisms are still largely unknown. In the present study, embryos of a native estuarine benthic fish, Mugilogobius chulae, were employed to investigate the developmental and behavioral toxic effects of ATV including environmentally relevant concentrati...
Source: Aquatic Toxicology - April 9, 2024 Category: Toxicology Authors: Yufei Zhao Yimeng Wang Jinzhi Ren Weibo Gong Xiangping Nie Ying Peng Jianjun Li Chunni Duan Source Type: research

Atorvastatin causes developmental and behavioral toxicity in yellowstripe goby (Mugilogobius chulae) embryos/larvae via disrupting lipid metabolism and autophagy processes
Aquat Toxicol. 2024 Apr 6;271:106909. doi: 10.1016/j.aquatox.2024.106909. Online ahead of print.ABSTRACTAtorvastatin (ATV) is one of the most commonly prescribed lipid-lowering drugs detected frequently in the environment due to its high use and low degradation rate. However, the toxic effects of residual ATV in the aquatic environment on non-target organisms and its toxic mechanisms are still largely unknown. In the present study, embryos of a native estuarine benthic fish, Mugilogobius chulae, were employed to investigate the developmental and behavioral toxic effects of ATV including environmentally relevant concentrati...
Source: Aquatic Toxicology - April 9, 2024 Category: Toxicology Authors: Yufei Zhao Yimeng Wang Jinzhi Ren Weibo Gong Xiangping Nie Ying Peng Jianjun Li Chunni Duan Source Type: research

Toxicity of butylone and its enantiomers to Daphnia magna and its degradation/toxicity potential using advanced oxidation technologies
Aquat Toxicol. 2024 Apr 4;271:106906. doi: 10.1016/j.aquatox.2024.106906. Online ahead of print.ABSTRACTButylone (BTL) is a chiral synthetic cathinone available as a racemate and reported as contaminant in wastewater effluents. However, there are no studies on its impact on ecosystems and possible enantioselectivity in ecotoxicity. This work aimed to evaluate: (i) the possible ecotoxicity of BTL as racemate or its isolated (R)- and (S)- enantiomers using Daphnia magna; and (ii) the efficiency of advanced oxidation technologies (AOTs) in the removal of BTL and reduction of toxic effects caused by wastewaters. Enantiomers of...
Source: Aquatic Toxicology - April 8, 2024 Category: Toxicology Authors: Ana R Carvalho Ana M Mor ão Virg ínia M F Gonçalves Maria Elizabeth Tiritan Ana M Gorito M Fernando Pereira Adri án M T Silva Bruno B Castro Jo ão S Carrola Maria M Amorim Ana R L Ribeiro Cl áudia Ribeiro Source Type: research

Biofilm enhances the interactive effects of microplastics and oxytetracycline on zebrafish intestine
This study emphasized the significant influence and unique role of biofilm in microplastic studies.PMID:38569307 | DOI:10.1016/j.aquatox.2024.106905 (Source: Aquatic Toxicology)
Source: Aquatic Toxicology - April 3, 2024 Category: Toxicology Authors: Ziyue Yu Donghua Qiu Tong Zhou Liqing Zeng Changzhou Yan Source Type: research

Biofilm enhances the interactive effects of microplastics and oxytetracycline on zebrafish intestine
This study emphasized the significant influence and unique role of biofilm in microplastic studies.PMID:38569307 | DOI:10.1016/j.aquatox.2024.106905 (Source: Aquatic Toxicology)
Source: Aquatic Toxicology - April 3, 2024 Category: Toxicology Authors: Ziyue Yu Donghua Qiu Tong Zhou Liqing Zeng Changzhou Yan Source Type: research

Biofilm enhances the interactive effects of microplastics and oxytetracycline on zebrafish intestine
This study emphasized the significant influence and unique role of biofilm in microplastic studies.PMID:38569307 | DOI:10.1016/j.aquatox.2024.106905 (Source: Aquatic Toxicology)
Source: Aquatic Toxicology - April 3, 2024 Category: Toxicology Authors: Ziyue Yu Donghua Qiu Tong Zhou Liqing Zeng Changzhou Yan Source Type: research