Characterization of Diclofenac-induced Renal Damage in Normotensive and Hypertensive Rats: A Comparative Analysis

Conclusions The data presented herein demonstrated that diclofenac induces
renal damage and impaired renal function in both NTR and SHR, but those effects
are exacerbated in SHR, as seen by the histological changes and electrolytes
balance disturbance, therefore, reinforcing that diclofenac may increase the
risks of cardiovascular events in hypertensive patients. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text

Source: Drug Research - March 19, 2024 Category: Drugs & Pharmacology Authors: Boeing, Thaise Lima, Alana Bittencourt F. Busana, Maria Eduarda Mariano, Lu ísa Nathália Bolda da Silva, Luisa Mota Silva, Rita de C ássia Vilhena da de Souza, Priscila Tags: Original Article Source Type: research