Vitamin B2 Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

High fatty acid accumulation and coloration molecular mechanism of the elm mushroom (Pleurotus citrinopileatus)
In conclusion, the expression of three SREBP, the synthesis of isobavachalcone D, and the regulation of riboflavin transport by MCH5 were the reasons for fatty acid accumulation and yellow cap formation in the P. citrinopileatus.PMID:38171531 | DOI:10.1093/bbb/zbad183 (Source: Bioscience, Biotechnology, and Biochemistry)
Source: Bioscience, Biotechnology, and Biochemistry - January 3, 2024 Category: Biochemistry Authors: Xuemei Bao Danmin Ke Wei Wang Fahui Ye Jiangyi Zeng Yuan Zong Source Type: research

Effects of riboflavin deficiency and high dietary fat on hepatic lipid accumulation: a synergetic action in the development of non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive lipid accumulation in the liver. Riboflavin, one of water soluble vitamins, plays a role in lipid metabolism and antioxidant function. Ho... (Source: Nutrition and Metabolism)
Source: Nutrition and Metabolism - January 2, 2024 Category: Nutrition Authors: Yanxian Wang, Xiangyu Bian, Min Wan, Weiyun Dong, Weina Gao, Zhanxin Yao and Changjiang Guo Tags: Research Source Type: research

The MR1/MAIT cell axis in CNS diseases
Brain Behav Immun. 2023 Dec 27:S0889-1591(23)00411-7. doi: 10.1016/j.bbi.2023.12.029. Online ahead of print.ABSTRACTMucosal-associated invariant T (MAIT) cells are a subpopulation of innate-like T cells that can be found throughout the body, predominantly in mucosal sites, the lungs and in the peripheral blood. MAIT cells recognize microbial-derived vitamin B (e.g., riboflavin) metabolite antigens that are presented by the major histocompatibility complex class I-like protein, MR1, found on a variety of cell types in the periphery and the CNS. Since their original discovery, MAIT cells have been studied predominantly in th...
Source: Brain, Behavior, and Immunity - December 29, 2023 Category: Neurology Authors: Rashmi Shrinivasan Season K Wyatt-Johnson Randy R Brutkiewicz Source Type: research

Photocrosslinked Co-Assembled Amino Acid Nanoparticles for Controlled Chemo/Photothermal Combined Anticancer Therapy
Small. 2023 Dec 28:e2307337. doi: 10.1002/smll.202307337. Online ahead of print.ABSTRACTNanostructures formed from the self-assembly of amino acids are promising materials in many fields, especially for biomedical applications. However, their low stability resulting from the weak noncovalent interactions between the amino acid building blocks limits their use. In this work, nanoparticles co-assembled by fluorenylmethoxycarbonyl (Fmoc)-protected tyrosine (Fmoc-Tyr-OH) and tryptophan (Fmoc-Trp-OH) are crosslinked by ultraviolet (UV) light irradiation. Two methods are investigated to induce the dimerization of tyrosine, irrad...
Source: Cancer Control - December 28, 2023 Category: Cancer & Oncology Authors: Tengfei Wang Yun Qi Eijiro Miyako Alberto Bianco C écilia Ménard-Moyon Source Type: research

Photocrosslinked Co ‐Assembled Amino Acid Nanoparticles for Controlled Chemo/Photothermal Combined Anticancer Therapy
Nanoparticles prepared from the co-assembly of Fmoc-protected tyrosine and Fmoc-protected tryptophan are stabilized using ultraviolet-induced crosslinking. After loading doxorubicin on the surface of these nanoparticles, they are coated with a tannic acid/Fe3+ complex, to impart photothermal properties and glutathione/pH-responsiveness, allowing to precisely control the drug release. The chemo/photothermal combined anticancer potential of these nanoparticles is evaluated in cancer cells and tumor-bearing mice. AbstractNanostructures formed from the self-assembly of amino acids are promising materials in many fields, especi...
Source: Small - December 28, 2023 Category: Nanotechnology Authors: Tengfei Wang, Yun Qi, Eijiro Miyako, Alberto Bianco, C écilia Ménard‐Moyon Tags: Research Article Source Type: research

Nutrition fact label (NFL) use is related to meeting the requirements for vitamins and minerals not listed on NFLs: Data from the Korea National Health and Nutritional Examination Survey VIII (2019 –2021) for the prepandemic and pandemic periods
by Jung Min Cho The credibility and wide usability of nutrition fact labels (NFLs) have increased due to the pandemic, which may lead to healthier nutritional choices. This cross-sectional study aimed to evaluate the association between NFL use and meeting the estimated average requirements (EARs) for vitamins an d minerals not listed on NFLs during the prepandemic (2019,n = 6606) and pandemic periods (2020 and 2021,n = 12085) using KNHANES data. Household surveys, health behavior interviews, and health checkup examinations were conducted for all participants. Subjects were included in the unAware+noUse, Aware+noUse, and ...
Source: PLoS One - December 28, 2023 Category: Biomedical Science Authors: Jung Min Cho Source Type: research

Riboflavin bio-enrichment of soy beverage by selected roseoflavin-resistant and engineered lactic acid bacteria
In this study, we explored two strategies to obtain riboflavin-overproducing strains: by roseoflavin selection of mutants, and by the transformation of selected strains with plasmids pNZ:TuR.rib or pNZ:TuB.rib containing the genes ribG, ribB, ribA and ribH from Lactococcus cremoris MG1363. The resulting riboflavin-overproducing strains were able to produce yields between 0.5 and 6 mg/L in culture media and several of them were selected for the fermentation of soy beverages. Riboflavin in bio-enriched soy beverages was evaluated by direct fluorescence measurement and high-performance liquid chromatography-fluorescence analy...
Source: International Journal of Food Microbiology - December 27, 2023 Category: Food Science Authors: Susana Langa Ángela Peirotén Susana Rodr íguez Javier Calzada Rub én Prieto-Paredes Jos é Antonio Curiel Jos é María Landete Source Type: research

Transglutaminase enables highly hydrolytically and proteolytically stable crosslinking of collagen on titanium surfaces and promotes osteogenic differentiation of human mesenchymal stem cells
In conclusion, the organochemical functionalization of Ti6Al4V surfaces with collagen using transglutaminase holds great potential to facilitate an enhanced interaction with attached bone cells and thereby could potentially improve and accelerate osseointegration of a titanium-based bone implant in vivo.PMID:38146594 | DOI:10.1002/jbm.a.37661 (Source: Biomed Res)
Source: Biomed Res - December 26, 2023 Category: Research Authors: Alena L Palkowitz Sascha R üger Maximilian Ziegler Eva Miriam Buhl Horst Fischer Source Type: research

Transglutaminase enables highly hydrolytically and proteolytically stable crosslinking of collagen on titanium surfaces and promotes osteogenic differentiation of human mesenchymal stem cells
In conclusion, the organochemical functionalization of Ti6Al4V surfaces with collagen using transglutaminase holds great potential to facilitate an enhanced interaction with attached bone cells and thereby could potentially improve and accelerate osseointegration of a titanium-based bone implant in vivo.PMID:38146594 | DOI:10.1002/jbm.a.37661 (Source: Cell Research)
Source: Cell Research - December 26, 2023 Category: Cytology Authors: Alena L Palkowitz Sascha R üger Maximilian Ziegler Eva Miriam Buhl Horst Fischer Source Type: research

Development of radiotracers for riboflavin transporter 3 imaging in diseases —A brief overview
RFVT3 is a potential biomarker for use in the diagnosis and therapy of RFVT3-overexpressed diseases, such as oncologic and neurodegenerative diseases. Riboflavin (RF, vitamin B2) plays a key role in metabolic oxidation –reduction reactions, especially in the mitochondrial reprogramming of energy metabolism. Riboflavin transporter 3 (RFVT3) is a vital section of the mitochondrial network and involved in riboflavin homeostasis and production of adenosine triphosphate (ATP). The abnormal expression of RFVT3 is clos ely associated with the occurrence and progression of multiple diseases. Therefore, it is vital to understand ...
Source: Journal of Labelled Compounds and Radiopharmaceuticals - December 23, 2023 Category: Biochemistry Authors: Jindian Li, Xianzhong Zhang Tags: PERSPECTIVE Source Type: research