Network pharmacology and molecular docking reveal the mechanisms of curcumin activity against esophageal squamous cell carcinoma
Conclusion: Collectively, these findings indicate that CUR exhibits pharmacological effects on multiple targets and pathways in ESCC. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - April 3, 2024 Category: Drugs & Pharmacology Source Type: research
The influence of plant extracts on viability of ST3 and ST7 subtypes of Blastocystis sp.
AbstractBlastocystis sp. is one of the most frequently detected protozoa during stool specimen examination. In the last decade, the studies about the pathogenic potential ofBlastocystis sp. have intensified. Additionally, treatment approaches against this parasite are still disputable. The study aimed to investigate the in vitro activity of the substances of natural origin against two subtypes (ST) ofBlastocystis sp. —ST3 and ST7. Garlic and turmeric extracts exhibited the highest inhibitory effect in relation to the ST3 viability. While horseradish and turmeric were found to be the most effective extracts to the ST7 v...
Source: Gut Pathogens - April 3, 2024 Category: Microbiology Source Type: research
Inhibitory effect of natural compounds on quorum sensing system in Pseudomonas aeruginosa: a helpful promise for managing biofilm community
This article explores many facets of utilizing natural compounds to inhibit and eradicate P. aeruginosa biofilms. It also examines the techniques and protocols employed to enhance the effectiveness of these compounds. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - April 2, 2024 Category: Drugs & Pharmacology Source Type: research
Improvement of Charcot-Marie-Tooth Phenotype with a Nanocomplex Treatment in Two Transgenic Models of CMT1A
This study shows that NanoCur shows therapeutic benefits with minimal systemic toxicity, suggesting that it is a potential therapeutic candidate for CMT1A and, possibly, for other neuropathies.PMID:38560579 | PMC:PMC10981932 | DOI:10.34133/bmr.0009 (Source: Cell Research)
Source: Cell Research - April 1, 2024 Category: Cytology Authors: Mohamed El Massry Zeina Msheik Tarek El Masri Gautier Ma Ndong Ntoutoume Laetitia Vignaud Laurence Richard Emilie Pinault Pierre-Antoine Faye Fr édérique Bregier Pierre Marquet Fr édéric Favreau Jean-Michel Vallat Fabrice Billet Vincent Sol Franck Stu Source Type: research
The Effects of Curcumin Plus Piperine Co-administration on Inflammation and Oxidative Stress: A Systematic Review and Meta-analysis of Randomized Controlled Trials
CONCLUSION: These results indicated that curcumin plus piperine administration could effectively reduce oxidative stress and inflammation.PMID:38561618 | DOI:10.2174/0109298673260515240322074849 (Source: Current Medicinal Chemistry)
Source: Current Medicinal Chemistry - April 1, 2024 Category: Chemistry Authors: Hossein Hosseini Farideh Ghavidel Arezoo Rajabian Masoud Homayouni-Tabrizi Muhammed Majeed Amirhossein Sahebkar Source Type: research
Protective Effects of Curcumin and Nanomicelle Curcumin on Chlorpyrifos-induced Oxidative Damage and Inflammation in the Uterus, Ovary and Brain of Rats
CONCLUSION: Our findings indicated that CUR and NMC could be effective in alleviating CPFinduced reproductive toxicity.PMID:38561608 | DOI:10.2174/0113892010297408240319073735 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - April 1, 2024 Category: Biotechnology Authors: Maryam Nazarian Hamed Aramjoo Babak Roshanravan Saeed Samarghandian Tahereh Farkhondeh Source Type: research
The Effects of Curcumin Plus Piperine Co-administration on Inflammation and Oxidative Stress: A Systematic Review and Meta-analysis of Randomized Controlled Trials
CONCLUSION: These results indicated that curcumin plus piperine administration could effectively reduce oxidative stress and inflammation.PMID:38561618 | DOI:10.2174/0109298673260515240322074849 (Source: Current Medicinal Chemistry)
Source: Current Medicinal Chemistry - April 1, 2024 Category: Chemistry Authors: Hossein Hosseini Farideh Ghavidel Arezoo Rajabian Masoud Homayouni-Tabrizi Muhammed Majeed Amirhossein Sahebkar Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
