Characterization and application of in situ curcumin/ZNP hydrogels for periodontitis treatment
Periodontitis is a chronic inflammatory disease that occurs in tooth-supporting tissues. Controlling inflammation and alleviating periodontal tissue destruction are key factors in periodontal therapy. This stu... (Source: BMC Oral Health)
Source: BMC Oral Health - March 28, 2024 Category: Dentistry Authors: Chengcheng Liu, Ying Chen, Huimin Bai, Yulong Niu and Yafei Wu Tags: Research Source Type: research

Pharmacological and immunomodulatory modes of action of medically important phytochemicals against arthritis: A molecular insight
Mol Biol Rep. 2024 Mar 27;51(1):448. doi: 10.1007/s11033-024-09386-9.ABSTRACTArthritis is a common illness that affects joints and it may result in inflammation and pain. Even though arthritis usually affects older people, it can also affect children, adults, and both genders. Numerous arthritic mouse models have been developed but the CIA model of rheumatoid arthritis (RA) has received the most attention. With the use of steroids, DMARDs, and NSAIDs, therapy objectives such as reduced disease incidence and better pain management are achieved. Long-term usage of these therapeutic approaches may have negative side effects. ...
Source: Molecular Biology Reports - March 27, 2024 Category: Molecular Biology Authors: None Aqsa Shaukat Ali Muhammad Summer Saima Yousaf Laiba Nazakat Shehzeen Noor Source Type: research

Curcumin mitigates ochratoxin A-induced oxidative stress and alters gene expression in  broiler chicken liver and kidney
Acta Vet Hung. 2024 Mar 26. doi: 10.1556/004.2024.01016. Online ahead of print.ABSTRACTThe study aimed to evaluate the effect of curcumin (CURC) supplementation on broiler chickens exposed to ochratoxin A (OTA), by examining biochemical parameters and the expression of glutathione redox system genes and their regulation. OTA reduced glutathione content in the liver while increasing glutathione peroxidase activity. CURC showed no significant effects. Kidney parameters remained mostly unaffected. Gene expression analysis revealed OTA-induced upregulation of KEAP1, NRF2, AHR, GPx4 and GSR genes in the liver. CURC supplementat...
Source: Acta Veterinaria Hungarica - March 27, 2024 Category: Veterinary Research Authors: Benj ámin Kövesi Adanu Paul Worlanyo Szabina Kulcs ár Zsolt Ancsin M árta Erdélyi Erika Z ándoki Mikl ós Mézes Kriszti án Balogh Source Type: research

Curcumin mitigates ochratoxin A-induced oxidative stress and alters gene expression in  broiler chicken liver and kidney
Acta Vet Hung. 2024 Mar 26. doi: 10.1556/004.2024.01016. Online ahead of print.ABSTRACTThe study aimed to evaluate the effect of curcumin (CURC) supplementation on broiler chickens exposed to ochratoxin A (OTA), by examining biochemical parameters and the expression of glutathione redox system genes and their regulation. OTA reduced glutathione content in the liver while increasing glutathione peroxidase activity. CURC showed no significant effects. Kidney parameters remained mostly unaffected. Gene expression analysis revealed OTA-induced upregulation of KEAP1, NRF2, AHR, GPx4 and GSR genes in the liver. CURC supplementat...
Source: Acta Veterinaria Hungarica - March 27, 2024 Category: Veterinary Research Authors: Benj ámin Kövesi Adanu Paul Worlanyo Szabina Kulcs ár Zsolt Ancsin M árta Erdélyi Erika Z ándoki Mikl ós Mézes Kriszti án Balogh Source Type: research

Curcumin mitigates ochratoxin A-induced oxidative stress and alters gene expression in  broiler chicken liver and kidney
Acta Vet Hung. 2024 Mar 26. doi: 10.1556/004.2024.01016. Online ahead of print.ABSTRACTThe study aimed to evaluate the effect of curcumin (CURC) supplementation on broiler chickens exposed to ochratoxin A (OTA), by examining biochemical parameters and the expression of glutathione redox system genes and their regulation. OTA reduced glutathione content in the liver while increasing glutathione peroxidase activity. CURC showed no significant effects. Kidney parameters remained mostly unaffected. Gene expression analysis revealed OTA-induced upregulation of KEAP1, NRF2, AHR, GPx4 and GSR genes in the liver. CURC supplementat...
Source: Acta Veterinaria Hungarica - March 27, 2024 Category: Veterinary Research Authors: Benj ámin Kövesi Adanu Paul Worlanyo Szabina Kulcs ár Zsolt Ancsin M árta Erdélyi Erika Z ándoki Mikl ós Mézes Kriszti án Balogh Source Type: research

Curcumin mitigates ochratoxin A-induced oxidative stress and alters gene expression in  broiler chicken liver and kidney
Acta Vet Hung. 2024 Mar 26. doi: 10.1556/004.2024.01016. Online ahead of print.ABSTRACTThe study aimed to evaluate the effect of curcumin (CURC) supplementation on broiler chickens exposed to ochratoxin A (OTA), by examining biochemical parameters and the expression of glutathione redox system genes and their regulation. OTA reduced glutathione content in the liver while increasing glutathione peroxidase activity. CURC showed no significant effects. Kidney parameters remained mostly unaffected. Gene expression analysis revealed OTA-induced upregulation of KEAP1, NRF2, AHR, GPx4 and GSR genes in the liver. CURC supplementat...
Source: Acta Veterinaria Hungarica - March 27, 2024 Category: Veterinary Research Authors: Benj ámin Kövesi Adanu Paul Worlanyo Szabina Kulcs ár Zsolt Ancsin M árta Erdélyi Erika Z ándoki Mikl ós Mézes Kriszti án Balogh Source Type: research

Curcumin mitigates ochratoxin A-induced oxidative stress and alters gene expression in  broiler chicken liver and kidney
Acta Vet Hung. 2024 Mar 26. doi: 10.1556/004.2024.01016. Online ahead of print.ABSTRACTThe study aimed to evaluate the effect of curcumin (CURC) supplementation on broiler chickens exposed to ochratoxin A (OTA), by examining biochemical parameters and the expression of glutathione redox system genes and their regulation. OTA reduced glutathione content in the liver while increasing glutathione peroxidase activity. CURC showed no significant effects. Kidney parameters remained mostly unaffected. Gene expression analysis revealed OTA-induced upregulation of KEAP1, NRF2, AHR, GPx4 and GSR genes in the liver. CURC supplementat...
Source: Acta Veterinaria Hungarica - March 27, 2024 Category: Veterinary Research Authors: Benj ámin Kövesi Adanu Paul Worlanyo Szabina Kulcs ár Zsolt Ancsin M árta Erdélyi Erika Z ándoki Mikl ós Mézes Kriszti án Balogh Source Type: research

Curcumin mitigates ochratoxin A-induced oxidative stress and alters gene expression in  broiler chicken liver and kidney
Acta Vet Hung. 2024 Mar 26. doi: 10.1556/004.2024.01016. Online ahead of print.ABSTRACTThe study aimed to evaluate the effect of curcumin (CURC) supplementation on broiler chickens exposed to ochratoxin A (OTA), by examining biochemical parameters and the expression of glutathione redox system genes and their regulation. OTA reduced glutathione content in the liver while increasing glutathione peroxidase activity. CURC showed no significant effects. Kidney parameters remained mostly unaffected. Gene expression analysis revealed OTA-induced upregulation of KEAP1, NRF2, AHR, GPx4 and GSR genes in the liver. CURC supplementat...
Source: Acta Veterinaria Hungarica - March 27, 2024 Category: Veterinary Research Authors: Benj ámin Kövesi Adanu Paul Worlanyo Szabina Kulcs ár Zsolt Ancsin M árta Erdélyi Erika Z ándoki Mikl ós Mézes Kriszti án Balogh Source Type: research