Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Dissemination of Information from Basic Research on Aging: Species, Strain, Substrain and Sex Differences
Yakugaku Zasshi. 2024;144(4):389-395. doi: 10.1248/yakushi.23-00165-1.ABSTRACTVarious organisms with different lifespans such as yeast, nematodes, fruit fly, mice, and rats are used for basic research on mechanisms of aging and anti-aging. These organisms are often genetically engineered and used to elucidate the contribution of certain genes to aging. For example, genetic recombination techniques revealed that the lifespan of superoxide dismutase (SOD) transgenic flies extended up to approximately 30%. This result suggests that increasing antioxidant capacity extends lifespan possibly by reducing oxidative damage. However...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - March 31, 2024 Category: Drugs & Pharmacology Authors: Ryoya Takahashi Keiko Odera Source Type: research
Anti-gouty arthritis and anti-inflammatory effects of curcumin nanoparticles in monosodium urate crystals induced Balb/C mice
This study aimed to investigate anti-gout and anti-inflammatory properties of curcumin nanoparticles (CNPs). For this purpose, CNPs were prepared by dissolving curcumin into dichloromethane. Then, gout was induced by injecting monosodium urate crystals (MSU) in the ankle joint and in the intra-per itoneal cavity which caused ankle swelling and increased blood uric acid levels. CNPs in different concentrations (5, 10, and 20 ppm) and allopurinol were orally administered. The MSU crystals increased the xanthine oxidase levels both in serum and the liver. Moreover, MSU crystals increased the se rum levels of interleukin 1β,...
Source: Inflammopharmacology - March 31, 2024 Category: Drugs & Pharmacology Source Type: research
