139. Ketamine ’s Efficacy in Suicidal Depressed Patients With Borderline Personality Disorder
Antidepressant treatment response is limited in patients with Major Depression (MDD) and comorbid Borderline Personality Disorder (BPD). However, recent studies suggest that intravenous ketamine may be an effective antidepressant treatment in this population. It is unknown if this treatment would be effective in MDD and comorbid BPD if suicidal ideation was elevated. (Source: Biological Psychiatry)
Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: John Keilp, Sumra Sajid, Sean P. Madden, J. John Mann, Michael Grunebaum Source Type: research
152. Deep Brain Stimulation for Treatment-Resistant Depression Changes Plasma Metabolic Markers
Treatment-refractory depression (TRD) occurs in approximately 30-35% of depression patients. As TRD persists, its burden increases exponentially, with impairments in functional and social functioning, loss of quality of life, and a higher risk of suicide. Deep brain stimulation (DBS) is emerging as a potential therapy. However, there is no objective biomarker that can predict clinical response. Here we examine whether metabolic/mitochondrial markers can predict treatment response in refractory depression patients receiving DBS to the medial forebrain bundle (slMFB). (Source: Biological Psychiatry)
Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Rafaela Carneiro Cordeiro, Franscisco Eliclecio Rodrigues da Silva, Bashar Asir, Giovana Zunta-Soares, Albert J. Fenoy, Jair Soares, Joao Quevedo, Giselli Scaini Source Type: research
160. Poly (ADP-Ribose) Polymerase-1 (PARP1) Expression in Major Depressive Disorder (MDD)
In this study, we evaluate the expression of PARP1 in two brain areas that have demonstrated pathology in MDD. Additionally, we evaluated the differences in a subgroup of individuals that died by suicide in the MDD group to those that did not die by suicide. (Source: Biological Psychiatry)
Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Ramona Fulkerson, Hui Wang-Heaton, Laura Cook, Abigail Cornett, Dalton Bellamy, Danielle Cates, Michelle Chandley Source Type: research
165. Examining the Relationship Between Cardiovascular Risk Factors and Suicide Phenotypes Among Youth With Mood Disorders
This study examined the association between cardiovascular risk with self-harm in a controlled sample of youth with mood disorders (bipolar disorder or major depressive disorder). (Source: Biological Psychiatry)
Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Mikaela Dimick, Kody G. Kennedy, Simin Jin, Benjamin Goldstein Source Type: research
Evaluating the impact of the Community Helpers Program on adolescents 12-18 years old in Edmonton, Canada
CONCLUSION: Findings show contextual effect of CHP; i.e., being potentially exposed to the program reduced the likelihood of anxiety- and depression-related visits. Costs of CHP implementation could be compared with the avoided costs to assess economic benefits of implementing CHP.PMID:38683287 | DOI:10.17269/s41997-024-00878-6 (Source: Canadian Journal of Public Health)
Source: Canadian Journal of Public Health - April 29, 2024 Category: International Medicine & Public Health Authors: Mohammad Habibullah Pulok Arthur Novaes de Amorim Sandra Johansen Kristin Pilon Christina Lucente Vineet Saini Source Type: research
Emergency Department Use in Adolescent and Young Adult Cancer Early Survivors from 2006 to 2020
Conclusion: ED utilization declined as time from diagnosis elapsed, but higher utilization was associated with social determinants of health and cancer types.PMID:38682323 | DOI:10.1089/jayao.2023.0174 (Source: Ann Oncol)
Source: Ann Oncol - April 29, 2024 Category: Cancer & Oncology Authors: Karen J Wernli Eric C Haupt Neetu Chawla Thearis Osuji Ernest Shen Andrew B Smitherman Mallory Casperson Anne C Kirchhoff Bradley J Zebrack Theresa H M Keegan Lawrence Kushi Christopher Baggett Heydon K Kaddas Kathryn J Ruddy Candice A M Sauder Theodore W Source Type: research
Evaluating the impact of the Community Helpers Program on adolescents 12-18 years old in Edmonton, Canada
CONCLUSION: Findings show contextual effect of CHP; i.e., being potentially exposed to the program reduced the likelihood of anxiety- and depression-related visits. Costs of CHP implementation could be compared with the avoided costs to assess economic benefits of implementing CHP.PMID:38683287 | DOI:10.17269/s41997-024-00878-6 (Source: Canadian Journal of Public Health)
Source: Canadian Journal of Public Health - April 29, 2024 Category: International Medicine & Public Health Authors: Mohammad Habibullah Pulok Arthur Novaes de Amorim Sandra Johansen Kristin Pilon Christina Lucente Vineet Saini Source Type: research
Prevalence of and risk factors for suicidal ideation in adolescents during the COVID-19 pandemic: a cross-sectional study
CONCLUSION: Our results show that a significant proportion of adolescents experience suicidal ideation, yet these rates are comparable with pre-pandemic results. Providing psychological support is fundamental, with a focus on improving parent-adolescent relationships.PMID:38679958 | DOI:10.57187/s.3461 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - April 29, 2024 Category: General Medicine Authors: Roxane Dumont Elsa Lorthe Viviane Richard Andrea Loizeau Guillaume Fernandez David De Ridder Francesco Pennacchio Julien Lamour Mar ía-Eugenia Zaballa Helene Baysson Klara M Posfay-Barbe Remy P Barbe Silvia Stringhini Idris Guessous Source Type: research
Emergency Department Use in Adolescent and Young Adult Cancer Early Survivors from 2006 to 2020
Conclusion: ED utilization declined as time from diagnosis elapsed, but higher utilization was associated with social determinants of health and cancer types.PMID:38682323 | DOI:10.1089/jayao.2023.0174 (Source: Ann Oncol)
Source: Ann Oncol - April 29, 2024 Category: Cancer & Oncology Authors: Karen J Wernli Eric C Haupt Neetu Chawla Thearis Osuji Ernest Shen Andrew B Smitherman Mallory Casperson Anne C Kirchhoff Bradley J Zebrack Theresa H M Keegan Lawrence Kushi Christopher Baggett Heydon K Kaddas Kathryn J Ruddy Candice A M Sauder Theodore W Source Type: research
Prevalence of and risk factors for suicidal ideation in adolescents during the COVID-19 pandemic: a cross-sectional study
CONCLUSION: Our results show that a significant proportion of adolescents experience suicidal ideation, yet these rates are comparable with pre-pandemic results. Providing psychological support is fundamental, with a focus on improving parent-adolescent relationships.PMID:38679958 | DOI:10.57187/s.3461 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - April 29, 2024 Category: General Medicine Authors: Roxane Dumont Elsa Lorthe Viviane Richard Andrea Loizeau Guillaume Fernandez David De Ridder Francesco Pennacchio Julien Lamour Mar ía-Eugenia Zaballa Helene Baysson Klara M Posfay-Barbe Remy P Barbe Silvia Stringhini Idris Guessous Source Type: research
Evaluating the impact of the Community Helpers Program on adolescents 12-18 years old in Edmonton, Canada
CONCLUSION: Findings show contextual effect of CHP; i.e., being potentially exposed to the program reduced the likelihood of anxiety- and depression-related visits. Costs of CHP implementation could be compared with the avoided costs to assess economic benefits of implementing CHP.PMID:38683287 | DOI:10.17269/s41997-024-00878-6 (Source: Canadian Journal of Public Health)
Source: Canadian Journal of Public Health - April 29, 2024 Category: International Medicine & Public Health Authors: Mohammad Habibullah Pulok Arthur Novaes de Amorim Sandra Johansen Kristin Pilon Christina Lucente Vineet Saini Source Type: research
Emergency Department Use in Adolescent and Young Adult Cancer Early Survivors from 2006 to 2020
Conclusion: ED utilization declined as time from diagnosis elapsed, but higher utilization was associated with social determinants of health and cancer types.PMID:38682323 | DOI:10.1089/jayao.2023.0174 (Source: Ann Oncol)
Source: Ann Oncol - April 29, 2024 Category: Cancer & Oncology Authors: Karen J Wernli Eric C Haupt Neetu Chawla Thearis Osuji Ernest Shen Andrew B Smitherman Mallory Casperson Anne C Kirchhoff Bradley J Zebrack Theresa H M Keegan Lawrence Kushi Christopher Baggett Heydon K Kaddas Kathryn J Ruddy Candice A M Sauder Theodore W Source Type: research
Can neurocognition, brain neurotrophic factor, triglyceride, and total cholesterol predict suicidal ideation in first ‐episode Han Chinese patients with schizophrenia?
ConclusionSerum BDNF level, PANSS score, and MCCB score can be used as auxiliary predictors of suicidal ideation in schizophrenic patients. Combining these three indicators can effectively predict suicidal ideation in schizophrenic patients. (Source: Brain and Behavior)
Source: Brain and Behavior - April 29, 2024 Category: Neurology Authors: Li Dongxia,
Ma Li,
Feng Yingying Tags: ORIGINAL ARTICLE Source Type: research
Suicide mortality following the implementation of tobacco packaging and pricing policies in Korea: an interrupted time-series analysis
To prevent tobacco use in Korea, the national quitline number was added to tobacco packages in December 2012, tobacco prices were raised by 80% in January 2015, and graphic health warning labels were placed on... (Source: BMC Medicine)
Source: BMC Medicine - April 29, 2024 Category: Internal Medicine Authors: Taiyue Jin, Juhee Seo, Shinhee Ye, Seulbi Lee, Eun Young Park, Jin-Kyoung Oh, Changwoo Han and Byungmi Kim Tags: Research article Source Type: research
Borderline Personality Traits Do Not Moderate the Relationship Between Depression, Beliefs, and Suicidal Thoughts and Behaviors
. (Source: Archives of Suicide Research)
Source: Archives of Suicide Research - April 29, 2024 Category: Psychiatry & Psychology Authors: Jessica StubbingDavid F. TolinKimberly S. SainKate EverhardtM. David RuddGretchen J. DiefenbachJessica Stubbing, The Center for Informed Futures, The University of Auckland, New Zealand.David F. Tolin, Anxiety Disorders Center, Institute of Living, Hartfo Source Type: research
