Risk factors for depression in adults: NR3C1 DNA methylation and lifestyle association
Publication date: Available online 16 October 2019Source: Journal of Psychiatric ResearchAuthor(s): Aline Ribeiro Borçoi, Suzanny Mendes de Oliveira, Joaquim Gasparini dos Santos, Mayara Mota de Oliveira, Ivana Alece Moreno Arantes, Flávia Vitorino Freitas, Júlia Assis Pinheiro, Juliana Krüger Arpini, Ester Ribeiro Cunha, Anderson Barros Archanjo, Aricia Leone Evangelista Monteiro de Assis, Bruna Pereira Sorroche, Lídia Maria Rebolho Batista Arantes, Elizeu Borloti, Adriana Madeira Álvares-da-SilvaAbstractObjectiveThe aim of this study was to verify determinant factors for depression...
Source: Journal of Psychiatric Research - October 16, 2019 Category: Psychiatry Source Type: research

In the shadow of National Socialism: Early emigration and suicide of the oral pathologist Rudolf Kronfeld (1901–1940)
Publication date: Available online 15 October 2019Source: Pathology - Research and PracticeAuthor(s): Katharina Reinecke, Jens Westemeier, Dominik GrossAbstractThe physician Rudolf Kronfeld (1901–1940) is undoubtedly one of the pioneering and most influential representatives of modern histopathology and oral pathology. Already at a young age he became a protagonist of the renowned, internationally leading “Vienna School”.Kronfeld’s outstanding professional significance stands in a peculiar contrast to the research situation to date: His curriculum vitae, but also his family background – and he...
Source: Pathology Research and Practice - October 16, 2019 Category: Pathology Source Type: research

Intracellular acting tumor cell-targeted chemotherapy by MSC-suicide gene exosomes.
Authors: Altaner C, Altanerova U, Jakubechova J PMID: 31608134 [PubMed] (Source: Oncotarget)
Source: Oncotarget - October 16, 2019 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

Burnout among specialists and trainees in physical medicine and rehabilitation: A systematic review.
CONCLUSION: Emerging evidence positions physicians in PMandR among the most likely to experience burnout. Although there is limited literature regarding PMandR specialists and trainees, the available evidence suggests that more than half of physicians in PMandR experience burnout. PMID: 31608964 [PubMed - as supplied by publisher] (Source: Journal of Rehabilitation Medicine)
Source: Journal of Rehabilitation Medicine - October 16, 2019 Category: Rehabilitation Tags: J Rehabil Med Source Type: research

Mental disorders, suicide attempt and suicide: differences in the association in refugees compared with Swedish-born individuals.
CONCLUSIONS: For most mental disorders, refugees were less likely to be admitted to hospital for suicide attempt or die by suicide compared with Swedish-born individuals. Further research on risk and protective factors for suicide attempt and suicide among refugees with mental disorders is warranted. DECLARATION OF INTEREST: None. PMID: 31608856 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 16, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Suicide risk among refugees compared with non-refugee migrants and the Swedish-born majority population.
CONCLUSIONS: Being a refugee was not an additional risk factor for suicide. Our findings regarding temporal changes in suicide risk suggest that acculturation and socioeconomic deprivation may account for a convergence of suicide risk between migrants and the host population over time. DECLARATION OF INTEREST: None. PMID: 31608849 [PubMed - as supplied by publisher] (Source: The British Journal of Psychiatry for Mental Science)
Source: The British Journal of Psychiatry for Mental Science - October 16, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research

Suicide Attempts by Black Adolescents Rising, Report Suggests
Between 1991 and 2017, the rate of black adolescents who reported attempting suicide rose, according to areport published Monday inPediatrics. This trend was not seen in adolescents who identified as white, Hispanic, Asian American or Pacific Islander, or being of multiple races.“Examining trends in suicidal ideation and behaviors over time by sex and race and ethnicity allows us to determine where to focus prevention and intervention efforts,” wrote Michael A. Lindsey, Ph.D., M.S.W., M.P.H., of New York University and colleagues.Lindsey and colleagues analyzed data from the Youth Risk Behavior Survey (YRBS) &m...
Source: Psychiatr News - October 15, 2019 Category: Psychiatry Tags: adolescents Benjamin Shain Michael Lindsey pediatrics suicide attempt suicide ideation Youth Risk Behavior Survey Source Type: research

Molecules, Vol. 24, Pages 3700: PI3K –AKT Signaling Activation and Icariin: The Potential Effects on the Perimenopausal Depression-Like Rat Model
Molecules, Vol. 24, Pages 3700: PI3K–AKT Signaling Activation and Icariin: The Potential Effects on the Perimenopausal Depression-Like Rat Model Molecules doi: 10.3390/molecules24203700 Authors: Li-Hua Cao Jing-Yi Qiao Hui-Yuan Huang Xiao-Yan Fang Rui Zhang Ming-San Miao Xiu-Min Li Icariin is a prenylated flavonol glycoside isolated from Epimedium herb, and has been shown to be its main bioactive component. Recently, the antidepressant-like mechanism of icariin has been increasingly evaluated and demonstrated. However, there are few studies that have focused on the involvement of the phosphatidyli...
Source: Molecules - October 15, 2019 Category: Chemistry Authors: Li-Hua Cao Jing-Yi Qiao Hui-Yuan Huang Xiao-Yan Fang Rui Zhang Ming-San Miao Xiu-Min Li Tags: Article Source Type: research

Error in Coding of Suicidal Ideation Questionnaire Scale
In the Original Investigation entitled “Grief in Children and Adolescents Bereaved by Sudden Parental Death” published in the September 2011 issue of JAMA Psychiatry (then Archives of General Psychiatry), the coding used for the Suicidal Ideation Questionnaire-Jr was incorrect. The scale ranges from 0 to 6; the authors had coded the scores on a scale from 1 to 7, which inflated the total scores. The resulting means were incorrect. The data in Table 2 were affected, but the errors did not affect the conclusions or interpretations of the study. A Letter of Explanation has been published that details the source of...
Source: JAMA Psychiatry - October 14, 2019 Category: Psychiatry Source Type: research

Error in Coding of Suicidal Ideation Questionnaire Scale
In the Original Investigation entitled “Switching to Another SSRI or to Venlafaxine With or Without Cognitive Behavioral Therapy for Adolescents With SSRI-Resistant Depression: the TORDIA Randomized Controlled Trial,” published in the February 27, 2008, issue of JAMA, the coding used for the Suicidal Ideation Questionnaire-Jr was inc orrect. The scale ranges from 0 to 6; we had coded the scores on a scale from 1 to 7, which inflated the total scores. The resulting means, CIs, and cut point for clinical significance were incorrect. The data in Table 1, the Results section, and Table 4 were affected, but the erro...
Source: JAMA - Journal of the American Medical Association - October 14, 2019 Category: General Medicine Source Type: research

Error in Coding of Suicidal Ideation Questionnaire Scale
This article has been corrected online. (Source: JAMA Pediatrics)
Source: JAMA Pediatrics - October 14, 2019 Category: Pediatrics Source Type: research

Concordant Actions in Suicide Assessment Model
This article offers an alternative conceptualization from which a health care provider can consider and respond to client-based suicidal ideation and behavior. Pragmatically explored through the prism of locus of control, Rogerian psychotherapy principles, Peplau's theory of interpersonal relations, and the work of Kay Redfield Jamison, the Concordant Actions in Suicide Assessment (CASA) model frames clinical decision making along a continuum defined by concordant and state-based action. Therein, cognitive reframes are offered to illustrate how to apply the CASA model in clinical practice. (Source: Nursing Clinics of North America)
Source: Nursing Clinics of North America - October 14, 2019 Category: Nursing Authors: Sean P. Convoy, Richard J. Westphal, Dana W. Convoy Source Type: research

On Pellegrino and Thomasma's Admission of a Dilemma and Inconsistency.
Abstract Edmund Pellegrino and David Thomasma's writings have had a worldwide impact on discourse about the philosophy of medicine, professionalism, bioethics, healthcare ethics, and patients' rights. Given their works' importance, it is surprising that commentators have ignored their admission of an unresolved and troubling dilemma and inconsistency in their theory. The purpose of this article is to identify and state what problems worried them and to consider possible solutions. It is argued that their dilemma stems from their concerns about how to justify professional rules restricting colleagues from performin...
Source: The Journal of Medicine and Philosophy - October 14, 2019 Category: Medical Ethics Authors: Kopelman LM Tags: J Med Philos Source Type: research

Risk Factors of Suicide Death Based on Psychological Autopsy Method; a Case-Control Study.
Conclusion: Previous suicide attempt, smoking, unemployment, and suffering from at least one mental disorder were the significant predictors of suicide death. Among mental disorders, major depressive disorder and substance use disorder were the most prevalent mental health problems. PMID: 31602433 [PubMed] (Source: Accident and Emergency Nursing)
Source: Accident and Emergency Nursing - October 13, 2019 Category: Emergency Medicine Authors: Rasouli N, Malakouti SK, Rezaeian M, Saberi SM, Nojomi M, De Leo D, Ramezani-Farani A Tags: Arch Acad Emerg Med Source Type: research

Making a murderer: Media renderings of brain injury and Aaron Hernandez as a medical and sporting subject
Publication date: Available online 12 October 2019Source: Social Science & MedicineAuthor(s): Hollin GregoryAbstractThis paper examines the entanglement of medicine, brain injury, and subjectivity within newspaper discourse and through the case of ex-American footballer Aaron Hernandez. In 2017, two years after being found guilty of murder and five years after scoring in the Super Bowl, Aaron Hernandez died by suicide in his prison cell. Hernandez was posthumously diagnosed with Chronic Traumatic Encephalopathy (CTE), a neurodegenerative disease associated with violence, depression, and dementia-like symptoms. I examin...
Source: Social Science and Medicine - October 12, 2019 Category: Psychiatry & Psychology Source Type: research

Chemokine alterations in the postmortem brains of suicide completers
We examined the concentrations of chemokines and related substances in the brain tissue from these two groups using the Bio-Plex Pro™ Human Chemokine Panel 40-Plex. We performed multiple regression analysis with covariates. The levels of CCL1, CCL8, CCL13, CCL15, CCL17, CCL19, CCL20, CXCL11, and IL-10 were significantly decreased, whereas the IL-16 levels were significantly increased in the suicide completers after adjustment with the Benjamini-Hochberg method to control for type Ⅰ errors (Q 
Source: Journal of Psychiatric Research - October 12, 2019 Category: Psychiatry Source Type: research

Traumatic brain injury (TBI) in collision sports: Possible mechanisms of transformation into chronic traumatic encephalopathy (CTE)
Traumatic brain injury (TBI) is a leading cause of death and disability, contributing to ~30% of all injury-related deaths in the US. TBI occurs when a force transmitted to the head causes neuropathologic damage and impairment of brain function. TBI doubles risk of suicide and is the major determinant of acquired seizure disorders. TBI arising from closed head trauma (CHT) significantly increases the risk of developing Alzheimer's disease (AD), Parkinson's disease (PD) and chronic traumatic encephalopathy (CTE). (Source: Metabolism - Clinical and Experimental)
Source: Metabolism - Clinical and Experimental - October 12, 2019 Category: Biomedical Science Authors: Theodore B. VanItallie Source Type: research

The SDQ dysregulation profile is associated with self-injurious thoughts and behaviors in adolescents evaluated at a clinical setting
ConclusionsOur results point to the role of self-regulatory problems in the presence of suicide plans, suicide gestures, suicide attempts, and in non-suicidal self-injury behavior. Longitudinal studies are needed to confirm the relationship between the Strengths and Difficulties Questionnaire-Dysregulation Profile and self-injurious thoughts and behaviors.ResumenIntroducciónLa ideación suicida, la conducta suicida y las conductas autolesivas sin intención suicida (autolesiones) son un grave problema de salud pública en la adolescencia. Una proporción significativa de de adolescentes evalu...
Source: Revista de Psiquiatria y Salud Mental - October 12, 2019 Category: Psychiatry Source Type: research

Psychiatric Home Hospitalisation Unit of the Hospital del Mar. A crisis resolution and home treatment team in Barcelona
ConclusionsThe results obtained in our study are consistent with previous results. Home crisis intervention teams have proved to be an alternative to traditional hospitalisation. However, more studies are needed to support these results.ResumenIntroducciónA pesar del desarrollo de la hospitalización domiciliaria en España durante los últimos años, es llamativa la escasez de literatura. El siguiente estudio pretende exponer los datos obtenidos por la Unidad de Hospitalización a Domicilio de Psiquiatría del Hospital del Mar (HADMar). HADMar es un programa de hospitalizaci&oacu...
Source: Revista de Psiquiatria y Salud Mental - October 12, 2019 Category: Psychiatry Source Type: research

Universal Mental Health Interventions for Children and Adolescents: A Systematic Review of Health Economic Evaluations
ConclusionFew studies were found, which limits the possibility of drawing strong conclusions about cost effectiveness. There is some evidence based on decision-analytic modelling that anti-bullying interventions represent value for money. Generally, there is a lack of studies that take into account long-term costs and effects.Systematic Review Registration NumberCRD42019115882. (Source: Applied Health Economics and Health Policy)
Source: Applied Health Economics and Health Policy - October 12, 2019 Category: Health Management Source Type: research

A Case of Cushing's Syndrome Misdiagnosed as Treatment Resistant Depression
Cushing's syndrome is a systemic disease resulting from chronic exposure to cortisol excess occurring at a rate of 0.7 to 2.4 per million per year.1,2 An abundance of glucocorticoid receptors found in the central nervous system makes the brain susceptible to states of glucocorticoid excess.1Depression is the most common neuropsychiatric manifestation of Cushing's syndrome, present in 50-80% of patients with active disease, with suicidal ideation reported at a rate of 17%.1 Neuropsychiatric symptoms can precede the onset of Cushing's syndrome3 making diagnosis challenging. (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - October 12, 2019 Category: General Medicine Authors: Jessica Marciano, Stavroula Christopoulos Tags: Clinical Communication to the Editor Source Type: research

Why Adolescents Attempt Suicide: A Qualitative Study of the Transition from Ideation to Action
. (Source: Archives of Suicide Research)
Source: Archives of Suicide Research - October 12, 2019 Category: Psychiatry & Psychology Authors: Kimberly H. McManama O ’Brien Alexandra Nicolopoulos Joanna Almeida Laika D. Aguinaldo Rochelle K. Rosen Source Type: research

Oral self-injury associated with septicaemia in a case of Cornelia de Lange syndrome
This report describes a case of septicaemia triggered by SI. The patient was a 40 year-old woman, who was diagnosed with Cornelia de Lange syndrome (CdLS). She was hospitalized in a medical long-term care sanatorium and was recently transferred from a familiar sanatorium. She started to bite herself on the mandibular labial alveolar mucosa; this had never been observed. As the self-biting wound gradually increased and the resultant inflammation spread to surrounding tissues, she was referred to our hospital. During the course of treatment, she suffered from septicaemia secondary to aspiration pneumonia. When a case of SI...
Source: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology - October 11, 2019 Category: ENT & OMF Source Type: research

Are volunteering and caregiving associated with suicide risk? A Census-based longitudinal study
Opposing risks have been identified between different prosocial activities, with volunteering having been linked to better mental health while caregiving has been associated with higher prevalence and incidenc... (Source: BMC Psychiatry)
Source: BMC Psychiatry - October 11, 2019 Category: Psychiatry Authors: Michael Rosato, Foteini Tseliou, David M. Wright, Aideen Maguire and Dermot O ’Reilly Tags: Research article Source Type: research

A Markerless Method for Genome Engineering in Zymomonas mobilis ZM4
Metabolic engineering of the biofuel-producing Zymomonas mobilis is necessary if we are to unlock the metabolic potential present in this non-model microbe. Manipulation of such organisms can be challenging because of the limited genetic tools for iterative genome modification. Here, we have developed an efficient method for generating markerless genomic deletions or additions in Z. mobilis. This is a two-step process that involves homologous recombination of an engineered suicide plasmid bearing Z. mobilis targeting sequences and a subsequent recombination event that leads to loss of the suicide plasmid and a genome modif...
Source: Frontiers in Microbiology - October 11, 2019 Category: Microbiology Source Type: research

Changes in Depressive Symptoms at Two-Week Treatment Mark May Predict 12-Week Remission Outcomes
Whether patients with major depressive disorder show improvement (or lack thereof) at the end of their second week on an antidepressant medication may predict whether they will ultimately achieve remission at the end of 12 weeks, astudy published inPsychiatric Research& Clinical Practice found.“For any antidepressant medication trial, it is important to identify as early as possible whether the patient is likely to achieve remission …,” wrote Paul B. Hicks, M.D., Ph.D., of Texas A&M College of Medicine and colleagues. “The present study bolsters the proposed use of the lack of early improve...
Source: Psychiatr News - October 10, 2019 Category: Psychiatry Tags: antidepressants bupropion depression early improvement Paul Hicks predictive values Psychiatric Research & Clinical Practice QIDS-C remission VAST-D Source Type: research

Suicidal ideation among health field undergraduates: prevalence and associated factors.
CONCLUSION: The high prevalence of suicidal ideation among university students in the health field reiterates the need to create intervention strategies, especially in the context of universities. PMID: 31596340 [PubMed - in process] (Source: Revista gaucha de enfermagem EENFUFRGS)
Source: Revista gaucha de enfermagem EENFUFRGS - October 10, 2019 Category: Nursing Tags: Rev Gaucha Enferm Source Type: research

Nonlinear change processes and the emergence of suicidal behavior: A conceptual model based on the fluid vulnerability theory of suicide
Publication date: April 2020Source: New Ideas in Psychology, Volume 57Author(s): Craig J. Bryan, Jonathan E. Butner, Alexis M. May, Kelsi F. Rugo, Julia A. Harris, D. Nicolas Oakey, David C. Rozek, AnnaBelle O. BryanAbstractAlthough ideation-to-action theories of suicide aim to explain the emergence of suicidal behaviors, researchers have primarily focused on the content of underlying mechanisms (i.e., who dies by suicide). Much less attention has focused on the temporal dynamics of suicide risk (i.e., when suicide occurs). The fluid vulnerability theory conceptualizes suicide as an inherently dynamic construct that follow...
Source: New Ideas in Psychology - October 10, 2019 Category: Psychiatry & Psychology Source Type: research

Changes In Plasma NPY, IL-1 & beta; And Hypocretin In People Who Died By Suicide
(Source: Neuropsychiatric Disease and Treatment)
Source: Neuropsychiatric Disease and Treatment - October 10, 2019 Category: Psychiatry Tags: Neuropsychiatric Disease and Treatment Source Type: research

Everyday Discrimination, Depressive Symptoms, and Suicide Ideation Among African American Men
. (Source: Archives of Suicide Research)
Source: Archives of Suicide Research - October 10, 2019 Category: Psychiatry & Psychology Authors: Janelle R. Goodwill Robert Joseph Taylor Daphne C. Watkins Source Type: research

Suicidal Thoughts and Behaviors Among LGBTQ Youth: Meta-Analyses and a Systematic Review
. (Source: Archives of Suicide Research)
Source: Archives of Suicide Research - October 10, 2019 Category: Psychiatry & Psychology Authors: Tyler Hatchel Joshua R. Polanin Dorothy L. Espelage Source Type: research

IJERPH, Vol. 16, Pages 3817: Association of Bedtime with both Suicidal Ideation and Suicide Planning among Korean Adolescents
Conclusions: We found that, among adolescents, going to bed after 01:30 is significantly associated with suicidal ideation and suicide planning, after adjusting for demographic, socioeconomic, and health-related characteristics. Therefore, late bedtime should be the timepoint of a suicide intervention for adolescents, in order to prevent developing suicidal ideations and suicide planning. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - October 10, 2019 Category: Environmental Health Authors: Wonjeong Jeong Yun Kyung Kim Hyeon Ji Lee Jieun Jang Selin Kim Eun-Cheol Park Sung-In Jang Tags: Article Source Type: research

IJERPH, Vol. 16, Pages 3815: Recipients of Suicide-Related Disclosure: The Link between Disclosure and Posttraumatic Growth for Suicide Attempt Survivors
el Melinda Moore It is important to explore factors that could help or hinder one’s wellbeing following a suicide attempt, which could yield not only negative consequences but also posttraumatic growth (PTG; positive changes following a traumatic event). The present study used a multivariate analysis of covariance (MANCOVA) to test the relationship between disclosure, PTG, and posttraumatic depreciation among suicide attempt survivors when controlling for time since attempt and to test whether these effects remained after controlling for quality of support from family and friends. Suicide attempt surviv...
Source: International Journal of Environmental Research and Public Health - October 10, 2019 Category: Environmental Health Authors: Laura M. Frey Christopher W. Drapeau Anthony Fulginiti Nathalie Oexle Dese ’Rae L. Stage Lindsay Sheehan Julie Cerel Melinda Moore Tags: Article Source Type: research

Borderline personality disorder and violence.
CONCLUSIONS: Violence in BPD patients is expressed particularly towards intimate partners and known persons, usually in the homes of perpetrators. Anger, impulsivity and avoiding abandonment are traits associated with violence while suicidal behaviour, identity disturbance and affective instability are not. These patients are disproportionately found in higher levels of secure care although most violence occurs in the community. In males it is more likely driven by substance use, often at transition from adolescence to adulthood, while more severe borderline pathology is implicated in women. Early identification of an at-r...
Source: Australasian Psychiatry - October 10, 2019 Category: Psychiatry Authors: Sarkar J Tags: Australas Psychiatry Source Type: research

Using resting-state intrinsic network connectivity to identify suicide risk in mood disorders.
Abstract BACKGROUND: Little is known about the neural substrates of suicide risk in mood disorders. Improving the identification of biomarkers of suicide risk, as indicated by a history of suicide-related behavior (SB), could lead to more targeted treatments to reduce risk. METHODS: Participants were 18 young adults with a mood disorder with a history of SB (as indicated by endorsing a past suicide attempt), 60 with a mood disorder with a history of suicidal ideation (SI) but not SB, 52 with a mood disorder with no history of SI or SB (MD), and 82 healthy comparison participants (HC). Resting-state functional...
Source: Psychological Medicine - October 10, 2019 Category: Psychiatry Authors: Stange JP, Jenkins LM, Pocius S, Kreutzer K, Bessette KL, DelDonno SR, Kling LR, Bhaumik R, Welsh RC, Keilp JG, Phan KL, Langenecker SA Tags: Psychol Med Source Type: research

Testing Basic Assumptions of the Interpersonal Needs Questionnaire-15 in a Sample of Clinically Depressed and Suicidal Youth.
CONCLUSION: Perceived burdensomeness appears to play a role in adolescent suicidality and may be a point of intervention, yet the notable deviation from previous findings and the relative weakness of two of the factors warrant further study. PMID: 31600010 [PubMed - as supplied by publisher] (Source: Suicide and Life-Threatening Behavior)
Source: Suicide and Life-Threatening Behavior - October 10, 2019 Category: Psychiatry & Psychology Authors: Hunt QA, Weiler LM, McGuire J, Mendenhall T, Kobak R, Diamond GS Tags: Suicide Life Threat Behav Source Type: research

Parvalbumin Promoter Methylation Altered in Major Depressive Disorder.
Conclusion: This study provides the first evidence of abnormalities of PVALB promoter methylation in MDD and its correlation with MDD severity indicating a role for epigenetics in this psychiatric disorder. PMID: 31588185 [PubMed - in process] (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - October 9, 2019 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

Violence and Suicide Risk Assessment in Youth with Psychotic Disorders
This article presents a careful review of the literature on violence risk and psychosis and suicide risk and psychosis as it pertains to youth or those who have been newly diagnosed with or are at high risk for psychotic disorders. Each topic is covered in reference to general considerations and specific psychotic symptoms (eg, hallucinations, delusions, paranoia). The reader can refer to practical boxes to assist in identifying relevant risk factors and examples of questions to ask the patient and family. (Source: Child and Adolescent Psychiatric Clinics of North America)
Source: Child and Adolescent Psychiatric Clinics of North America - October 9, 2019 Category: Psychiatry Authors: Charles L. Scott, Anne B. McBride Source Type: research

Ethnic Identity and Suicide Risk among Hispanic/Latinx Young Adults: The Impact of Perceived Burdensomeness and Thwarted Belongingness
. (Source: Archives of Suicide Research)
Source: Archives of Suicide Research - October 9, 2019 Category: Psychiatry & Psychology Authors: Nicolas Oakey-Frost Raymond P. Tucker Julia D. Buckner Source Type: research

Relationship between Lithium Levels in Drinking Water and Suicide Rates: A Nationwide Study in Lithuania
. (Source: Archives of Suicide Research)
Source: Archives of Suicide Research - October 9, 2019 Category: Psychiatry & Psychology Authors: Vilma Liaugaudaite Rima Naginiene Nijole Raskauskiene Narseta Mickuviene Adomas Bunevicius Leo Sher Source Type: research

How intelligence and emotional control are related to suicidal behavior across the life course - A register-based study with 38-year follow-up.
CONCLUSIONS: The study adds to previous research by showing that the association between poor emotional control and subsequent suicide risk in men becomes weaker over the life course, while the association between low intelligence and suicide risk seems to be constant. The particularly high suicide risk of young men with poor emotional control may motivate targeted prevention efforts. PMID: 31594550 [PubMed - as supplied by publisher] (Source: Psychological Medicine)
Source: Psychological Medicine - October 9, 2019 Category: Psychiatry Authors: Hansson Bittár N, Falkstedt D, Sörberg Wallin A Tags: Psychol Med Source Type: research

Psychiatric morbidity and suicidal behaviour in low- and middle-income countries: A systematic review and meta-analysis
ConclusionsOur findings suggest a possible lower prevalence of psychiatric disorders in suicidal behaviour in LMIC. We found very few high-quality studies and high levels of heterogeneity in pooled estimates of psychiatric disorder, which could reflect differing study methods or real differences. There is a clear need for more robust evidence in order for LMIC to strike the right balance between community-based and mental health focussed interventions. (Source: PLoS Medicine)
Source: PLoS Medicine - October 9, 2019 Category: Internal Medicine Authors: Duleeka Knipe Source Type: research

Study Highlights Long-Term Benefits of Deep Brain Stimulation for Refractory Depression
Deep brain stimulation (DBS) of a region called the subcallosal cingulate appears to be safe and effective at reducing symptoms of depression in patients with treatment-resistant depression over time, according to asmall study inAJP in Advance.Previous studies suggest that up to one-third of all patients with major depression have treatment-resistant depression (that is, they fail to experience symptom improvements during two or more antidepressant trials). “Given that patients with treatment-resistant depression are highly susceptible to recurrent depressive episodes, the ability of DBS or any treatment to support l...
Source: Psychiatr News - October 8, 2019 Category: Psychiatry Tags: ajp in advance Andrea Crowell bipolar disorder DBS deep brain stimulation functioning HAM-D subcallosal cingulate surgery treatment-resistant depression Source Type: research

Sex differences in patients with suicidal intent that are managed by toxicologists
The Toxicology Investigator ’s Consortium (ToxIC) maintains a prospective case registry of all patients that have been managed at the bedside by medical toxicologists. We set out to characterize the differences in toxicological suicide attempts between men and women among adult patients with poisonings managed by medical tox icologists. (Source: The American Journal of Emergency Medicine)
Source: The American Journal of Emergency Medicine - October 8, 2019 Category: Emergency Medicine Authors: Gillian A. Beauchamp, Jacob Fishbein, Gregory A. Makar, Rita M. Pechulis, Matthew D. Cook, Robert D. Cannon, Kenneth D. Katz, Hope Kincaid, Jennifer L. Carey, Marna Rayl Greenberg, On behalf of Toxicology Investigators' Consortium (ToxIC) Source Type: research

Role of primary care in supporting older adults who self-harm: a qualitative study in England.
CONCLUSION: Despite older adults' frequent contact with GPs, barriers to primary care existed, which included stigma, previous negative experiences, and practical barriers such as mobility restrictions. Older adults' help-seeking behaviour was facilitated by previous positive experiences. Primary care is a potential avenue for delivering effective self-harm support, management, and suicide prevention in older adults. Given the complex nature of self-harm, there is a need for primary care to work with other sectors to provide comprehensive support to older adults who self-harm. PMID: 31594769 [PubMed - as supplied by p...
Source: The British Journal of General Practice - October 8, 2019 Category: Primary Care Authors: Troya MI, Chew-Graham CA, Babatunde O, Bartlam B, Mughal F, Dikomitis L Tags: Br J Gen Pract Source Type: research

Project Synergy: co-designing technology-enabled solutions for Australian mental health services reform.
Authors: Hickie IB, Davenport TA, Burns JM, Milton AC, Ospina-Pinillos L, Whittle L, Ricci CS, McLoughlin LT, Mendoza J, Cross SP, Piper SE, Iorfino F, LaMonica HM Abstract Project Synergy aims to test the potential of new and emerging technologies to enhance the quality of mental health care provided by traditional face-to-face services. Specifically, it seeks to ensure that consumers get the right care, first time (delivery of effective mental health care early in the course of illness). Using co-design with affected individuals, Project Synergy has built, implemented and evaluated an online platform to assist th...
Source: Medical Journal of Australia - October 7, 2019 Category: General Medicine Tags: Med J Aust Source Type: research

Association of lipid profile with completed suicides: A hospital-based case-control study.
Authors: Anuragi RP, Lakshmy R, Bhardwaj DN, Bharti DR, Sikary AK, Behera C PMID: 31586796 [PubMed - as supplied by publisher] (Source: Asian Journal of Psychiatry)
Source: Asian Journal of Psychiatry - October 7, 2019 Category: Psychiatry Tags: Asian J Psychiatr Source Type: research

Suicide attempts by self-poisoning in the United States among 10 –25 year olds from 2000 to 2018: substances used, temporal changes and demographics
. (Source: Clinical Toxicology)
Source: Clinical Toxicology - October 7, 2019 Category: Toxicology Authors: Henry A. Spiller John P. Ackerman Gary A. Smith Sandhya Kistamgari Alexandra R. Funk Michael R. McDermott Marcel J. Casavant Source Type: research

Cell Competition Triggers Suicide by Autophagy.
Abstract Cell competition eradicates weaker cells from an epithelium and is important for organ homeostasis. In this issue of Developmental Cell, Nagata et al. (2019) uncover that eradication of loser cells depends on autophagy-mediated cell death. PMID: 31593651 [PubMed - in process] (Source: Developmental Cell)
Source: Developmental Cell - October 7, 2019 Category: Cytology Authors: Dillard C, Rusten TE Tags: Dev Cell Source Type: research

Suicide attempts by self-poisoning in the United States among 10 –25 year olds from 2000 to 2018: substances used, temporal changes and demographics
. (Source: Clinical Toxicology)
Source: Clinical Toxicology - October 7, 2019 Category: Toxicology Authors: Henry A. Spiller John P. Ackerman Gary A. Smith Sandhya Kistamgari Alexandra R. Funk Michael R. McDermott Marcel J. Casavant Source Type: research