Evaluation of Conditions for the Development of Cryogenic Spinal Cord Injury Using a Canine Model: An Experimental Study on the Safety of Cryoablation for Metastatic Spinal Tumors [NEUROINTERVENTION]
CONCLUSIONS:
This study showed that 10-minute spinal cryoablation with LETs (°C) of –37, –30, –27, –8, 0, and 1 caused cryogenic spinal cord injury. There was no evidence of cryogenic spinal cord injury in canines with LET of ≥4°C. The epidural temperature threshold for cryogenic spinal cord injury is between 1 and 4°C, suggesting that the epidural temperature should be maintained above at least 4°C to prevent cryogenic spinal cord injury. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - April 8, 2024 Category: Radiology Authors: Kobayashi, M., Kato, S., Demura, S., Yokogawa, N., Yokka, A., Nakade, Y., Annen, R., Gabata, T., Tsuchiya, H. Tags: NEUROINTERVENTION Source Type: research
SP1 transcriptionally activates HTR2B to aggravate traumatic spinal cord injury by shifting microglial M1/M2 polarization
Spinal cord injury (SCI) can result in structural and functional damage to the spinal cord, which may lead to loss of limb movement and sensation, loss of bowel and bladder control, and other complications. Pr... (Source: Journal of Orthopaedic Surgery and Research)
Source: Journal of Orthopaedic Surgery and Research - April 8, 2024 Category: Orthopaedics Authors: Qifei Xu, Fanguo Kong, Guanghui Zhao, Junwei Jin, Shengkai Feng and Ming Li Tags: Research article Source Type: research
MST2 Acts via AKT Activity to Promote Neurite Outgrowth and Functional Recovery after Spinal Cord Injury in Mice
In conclusion, our findings affirmed MST2’s pivotal role in fostering neuronal neurite outgrowth and facilitating functional recovery after SCI, mediated thro ugh its positive modulation of AKT activity. In conclusion, our findings confirmed MST2’s crucial role in neural protection, promoting neurite outgrowth and functional recovery after SCI through positive AKT activity modulation. These results position MST2 as a potential therapeutic target for SCI , offering new insights into strategies for enhancing neuroregeneration and functional restoration. (Source: Molecular Neurobiology)
Source: Molecular Neurobiology - April 6, 2024 Category: Neurology Source Type: research
Letter to the Editor on “A Single Dermatome Clinical Prediction Rule for Independent Walking 1 Year After Spinal Cord Injury”
This study evaluated the use of a single dermatome as a valuable clinical tool to predict independent walking one year after traumatic spinal cord injuries (SCI). While the study is recommendable for its effort to address a challenging yet clinically important question, several aspects merit further attention and exploration by the authors. (Source: Archives of Physical Medicine and Rehabilitation)
Source: Archives of Physical Medicine and Rehabilitation - April 5, 2024 Category: Rehabilitation Authors: Jing Chen Tags: Letter to the Editor Source Type: research
Hypothermia effects on neuronal plasticity post spinal cord injury
ConclusionOur results show that the forelimbs SSEP signals from the two groups of injuries with and without hypothermia have statistically significant differences on days 4 and 7. This indicates the neuroprotective effect of early hypothermia and its influences on stimulating further the neuroplasticity within the upper limbs neural network post-SCI. Timely detection of neuroplasticity and identifying the endogenous and exogenous factors have clinical applications in planning a more effective rehabilitation and functional electrical stimulation (FES) interventions in SCI patients. (Source: PLoS One)
Source: PLoS One - April 5, 2024 Category: Biomedical Science Authors: Hasan Al-Nashash Source Type: research
Treatment of Syringomyelia Characterized by Focal Dilatation of the Central Canal Using Mesenchymal Stem Cells and Neural Stem Cells
CONCLUSION:Cell transplantation can promote cavity shrinkage and regulate the local inflammatory environment. Moreover, the proliferation of ependymal cells may indicate the activation of endogenous stem cells, which is important for the regeneration and repair of spinal cord injury. (Source: Tissue Engineering and Regenerative Medicine)
Source: Tissue Engineering and Regenerative Medicine - April 5, 2024 Category: Biotechnology Source Type: research
Impact of Upper Limb Motor Recovery on Functional Independence After Traumatic Low Cervical Spinal Cord Injury
Journal of Neurotrauma, Ahead of Print. (Source: Journal of Neurotrauma)
Source: Journal of Neurotrauma - April 5, 2024 Category: Neurology Authors: Saad Javeed Justin K. Zhang Jacob K. Greenberg Kathleen Botterbush Braeden Benedict Benjamin Plog Vivek P. Gupta Christopher F. Dibble Jawad M. Khalifeh Huacong Wen Yuying Chen Yikyung Park Allan Belzberg Sami Tuffaha Stephen Shelby Burks Allan D. Levi Er Source Type: research
Defining malnutrition in persons with spinal cord injury - does the Global Criteria for Malnutrition work?
CONCLUSIONS: In this cross-sectional study, 62% of subacute SCI patients were malnourished according to the GLIM criteria. The screening tool MUST showed moderate agreement with the GLIM criteria and did not detect risk of all patients with a malnutrition diagnosis. The clinical implications of these findings need further investigation.PMID:38571922 | PMC:PMC10989229 | DOI:10.29219/fnr.v68.9989 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Hanne Bj ørg Slettahjell Maria Bastakis Fin Biering-S ørensen Vegard Str øm Christine Henriksen Source Type: research
Defining malnutrition in persons with spinal cord injury - does the Global Criteria for Malnutrition work?
CONCLUSIONS: In this cross-sectional study, 62% of subacute SCI patients were malnourished according to the GLIM criteria. The screening tool MUST showed moderate agreement with the GLIM criteria and did not detect risk of all patients with a malnutrition diagnosis. The clinical implications of these findings need further investigation.PMID:38571922 | PMC:PMC10989229 | DOI:10.29219/fnr.v68.9989 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Hanne Bj ørg Slettahjell Maria Bastakis Fin Biering-S ørensen Vegard Str øm Christine Henriksen Source Type: research
Defining malnutrition in persons with spinal cord injury - does the Global Criteria for Malnutrition work?
CONCLUSIONS: In this cross-sectional study, 62% of subacute SCI patients were malnourished according to the GLIM criteria. The screening tool MUST showed moderate agreement with the GLIM criteria and did not detect risk of all patients with a malnutrition diagnosis. The clinical implications of these findings need further investigation.PMID:38571922 | PMC:PMC10989229 | DOI:10.29219/fnr.v68.9989 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Hanne Bj ørg Slettahjell Maria Bastakis Fin Biering-S ørensen Vegard Str øm Christine Henriksen Source Type: research
Defining malnutrition in persons with spinal cord injury - does the Global Criteria for Malnutrition work?
CONCLUSIONS: In this cross-sectional study, 62% of subacute SCI patients were malnourished according to the GLIM criteria. The screening tool MUST showed moderate agreement with the GLIM criteria and did not detect risk of all patients with a malnutrition diagnosis. The clinical implications of these findings need further investigation.PMID:38571922 | PMC:PMC10989229 | DOI:10.29219/fnr.v68.9989 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Hanne Bj ørg Slettahjell Maria Bastakis Fin Biering-S ørensen Vegard Str øm Christine Henriksen Source Type: research
Defining malnutrition in persons with spinal cord injury - does the Global Criteria for Malnutrition work?
CONCLUSIONS: In this cross-sectional study, 62% of subacute SCI patients were malnourished according to the GLIM criteria. The screening tool MUST showed moderate agreement with the GLIM criteria and did not detect risk of all patients with a malnutrition diagnosis. The clinical implications of these findings need further investigation.PMID:38571922 | PMC:PMC10989229 | DOI:10.29219/fnr.v68.9989 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Hanne Bj ørg Slettahjell Maria Bastakis Fin Biering-S ørensen Vegard Str øm Christine Henriksen Source Type: research
Defining malnutrition in persons with spinal cord injury - does the Global Criteria for Malnutrition work?
CONCLUSIONS: In this cross-sectional study, 62% of subacute SCI patients were malnourished according to the GLIM criteria. The screening tool MUST showed moderate agreement with the GLIM criteria and did not detect risk of all patients with a malnutrition diagnosis. The clinical implications of these findings need further investigation.PMID:38571922 | PMC:PMC10989229 | DOI:10.29219/fnr.v68.9989 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Hanne Bj ørg Slettahjell Maria Bastakis Fin Biering-S ørensen Vegard Str øm Christine Henriksen Source Type: research
Defining malnutrition in persons with spinal cord injury - does the Global Criteria for Malnutrition work?
CONCLUSIONS: In this cross-sectional study, 62% of subacute SCI patients were malnourished according to the GLIM criteria. The screening tool MUST showed moderate agreement with the GLIM criteria and did not detect risk of all patients with a malnutrition diagnosis. The clinical implications of these findings need further investigation.PMID:38571922 | PMC:PMC10989229 | DOI:10.29219/fnr.v68.9989 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Hanne Bj ørg Slettahjell Maria Bastakis Fin Biering-S ørensen Vegard Str øm Christine Henriksen Source Type: research
Defining malnutrition in persons with spinal cord injury - does the Global Criteria for Malnutrition work?
CONCLUSIONS: In this cross-sectional study, 62% of subacute SCI patients were malnourished according to the GLIM criteria. The screening tool MUST showed moderate agreement with the GLIM criteria and did not detect risk of all patients with a malnutrition diagnosis. The clinical implications of these findings need further investigation.PMID:38571922 | PMC:PMC10989229 | DOI:10.29219/fnr.v68.9989 (Source: Food and Nutrition Research)
Source: Food and Nutrition Research - April 4, 2024 Category: Nutrition Authors: Hanne Bj ørg Slettahjell Maria Bastakis Fin Biering-S ørensen Vegard Str øm Christine Henriksen Source Type: research
