Transabdominal Motor Evoked Potential Neuromonitoring of Lumbosacral Spine Surgery
Transcranial Motor Evoked Potentials (TcMEPs) can improve intraoperative detection of femoral plexus and nerve root injury during lumbosacral spine surgery. However, even under ideal conditions, TcMEPs are not completely free of false-positive alerts due to the immobilizing effect of general anesthetics, especially in the proximal musculature. The application of transcutaneous stimulation to activate ventral nerve roots directly at the level of the conus medularis (bypassing the brain and spinal cord) has emerged as a method to potentially monitor the motor component of the femoral plexus and lumbosacral nerves free from t...
Source: The Spine Journal - April 27, 2024 Category: Orthopaedics Authors: David W. Allison, Amit Verma, Paul J. Holman, Meng Huang, Todd W. Trask, Sean M. Barber, Anthony R. Cockrell, Matthew R. Weber, Dalton W. Brooks, Leo Delgado, William J. Steele, Jonathan N. Sellin, Loyola V. Gressot, Bradley Lambert, Brandy B. Ma, Amir H. Tags: Clinical Study Source Type: research

Development and content validity of the caregiver assisted transfer technique instrument
Assist Technol. 2024 Apr 26:1-9. doi: 10.1080/10400435.2024.2336334. Online ahead of print.ABSTRACTInformal caregivers often provide transfer assistance to individuals with disabilities; however, repeated transfers are associated with a high risk of musculoskeletal pain and injury, and training and education around transfers is minimal. The purpose of this study was to develop and assess the content validity of a new tool, the Caregiver Assisted Transfer Technique Instrument (CATT), which could be used to provide an objective indicator of transfer performance. Item importance, clarity, and appropriateness of responses were...
Source: Assistive Technology - April 26, 2024 Category: Rehabilitation Authors: Hailee R Kulich Diane Collins Brad E Dicianno Luci Leykum Lynn Worobey Rory Cooper Alicia M Koontz Source Type: research

Analgesic Mechanism of Dexmedetomidine and Esketamine in Rats with Spinal Cord Injury
CONCLUSIONS: Treatment using DEX combined with ESK improves the motor function, inhibits inflammation and astrocyte activity, and exerts analgesic effects on rats with SCI. These findings can serve as a reference for the selection of multi-modal analgesics.PMID:38665020 | DOI:10.24976/Discov.Med.202436183.67 (Source: Discovery Medicine)
Source: Discovery Medicine - April 26, 2024 Category: Research Authors: Huiting Zhao Zhuocheng Li Source Type: research

Musculoskeletal morbidity in adults with spinal cord injuries: A nationwide cohort study
CONCLUSION: SCI increases the risk of MSK morbidity. Lumbar SCI is associated with a higher incidence and risk of MSK morbidity than are cervical or thoracic SCIs.PMID:38669487 | DOI:10.3233/NRE-230263 (Source: NeuroRehabilitation)
Source: NeuroRehabilitation - April 26, 2024 Category: Rehabilitation Authors: Youngoh Bae Hohyun Jung Nakyung Shin Masoud Rahmati Raphael Udeh Abdolreza Kazemi Yusheng Li Marco Solmi Muhammad Syafrudin Norma Latif Fitriyani Guillaume Fond Laurent Boyer Seung Won Lee Source Type: research

Galectin-3 absence alters lymphocytes populations dynamics behavior and promotes functional recovery after spinal cord injury in mice
In conclusion, GALNEG mice exhibited better functional recovery attributed to the milder pro-inflammatory influence, compensated by a higher quantity of T Reg and Th2 cells. These findings suggest that galectin-3 plays a crucial role in the immune response after spinal cord injury and could be a potential target for clinical therapeutic interventions.PMID:38670250 | DOI:10.1016/j.expneurol.2024.114785 (Source: Experimental Neurology)
Source: Experimental Neurology - April 26, 2024 Category: Neurology Authors: Caio Andrade Prins Felipe Leite de Oliveira Valeria de Mello Coelho Emanuela Bezerra Dos Santos Ribeiro Juliana Silva de Almeida Natalia Moraes Bechelli Silva Fernanda Martins Almeida Ana Maria Blanco Martinez Source Type: research

Development and content validity of the caregiver assisted transfer technique instrument
Assist Technol. 2024 Apr 26:1-9. doi: 10.1080/10400435.2024.2336334. Online ahead of print.ABSTRACTInformal caregivers often provide transfer assistance to individuals with disabilities; however, repeated transfers are associated with a high risk of musculoskeletal pain and injury, and training and education around transfers is minimal. The purpose of this study was to develop and assess the content validity of a new tool, the Caregiver Assisted Transfer Technique Instrument (CATT), which could be used to provide an objective indicator of transfer performance. Item importance, clarity, and appropriateness of responses were...
Source: Assistive Technology - April 26, 2024 Category: Rehabilitation Authors: Hailee R Kulich Diane Collins Brad E Dicianno Luci Leykum Lynn Worobey Rory Cooper Alicia M Koontz Source Type: research

Analgesic Mechanism of Dexmedetomidine and Esketamine in Rats with Spinal Cord Injury
CONCLUSIONS: Treatment using DEX combined with ESK improves the motor function, inhibits inflammation and astrocyte activity, and exerts analgesic effects on rats with SCI. These findings can serve as a reference for the selection of multi-modal analgesics.PMID:38665020 | DOI:10.24976/Discov.Med.202436183.67 (Source: Discovery Medicine)
Source: Discovery Medicine - April 26, 2024 Category: Research Authors: Huiting Zhao Zhuocheng Li Source Type: research

Musculoskeletal morbidity in adults with spinal cord injuries: A nationwide cohort study
CONCLUSION: SCI increases the risk of MSK morbidity. Lumbar SCI is associated with a higher incidence and risk of MSK morbidity than are cervical or thoracic SCIs.PMID:38669487 | DOI:10.3233/NRE-230263 (Source: NeuroRehabilitation)
Source: NeuroRehabilitation - April 26, 2024 Category: Rehabilitation Authors: Youngoh Bae Hohyun Jung Nakyung Shin Masoud Rahmati Raphael Udeh Abdolreza Kazemi Yusheng Li Marco Solmi Muhammad Syafrudin Norma Latif Fitriyani Guillaume Fond Laurent Boyer Seung Won Lee Source Type: research

Development and content validity of the caregiver assisted transfer technique instrument
Assist Technol. 2024 Apr 26:1-9. doi: 10.1080/10400435.2024.2336334. Online ahead of print.ABSTRACTInformal caregivers often provide transfer assistance to individuals with disabilities; however, repeated transfers are associated with a high risk of musculoskeletal pain and injury, and training and education around transfers is minimal. The purpose of this study was to develop and assess the content validity of a new tool, the Caregiver Assisted Transfer Technique Instrument (CATT), which could be used to provide an objective indicator of transfer performance. Item importance, clarity, and appropriateness of responses were...
Source: Assistive Technology - April 26, 2024 Category: Rehabilitation Authors: Hailee R Kulich Diane Collins Brad E Dicianno Luci Leykum Lynn Worobey Rory Cooper Alicia M Koontz Source Type: research

Analgesic Mechanism of Dexmedetomidine and Esketamine in Rats with Spinal Cord Injury
CONCLUSIONS: Treatment using DEX combined with ESK improves the motor function, inhibits inflammation and astrocyte activity, and exerts analgesic effects on rats with SCI. These findings can serve as a reference for the selection of multi-modal analgesics.PMID:38665020 | DOI:10.24976/Discov.Med.202436183.67 (Source: Discovery Medicine)
Source: Discovery Medicine - April 26, 2024 Category: Research Authors: Huiting Zhao Zhuocheng Li Source Type: research

Musculoskeletal morbidity in adults with spinal cord injuries: A nationwide cohort study
CONCLUSION: SCI increases the risk of MSK morbidity. Lumbar SCI is associated with a higher incidence and risk of MSK morbidity than are cervical or thoracic SCIs.PMID:38669487 | DOI:10.3233/NRE-230263 (Source: NeuroRehabilitation)
Source: NeuroRehabilitation - April 26, 2024 Category: Rehabilitation Authors: Youngoh Bae Hohyun Jung Nakyung Shin Masoud Rahmati Raphael Udeh Abdolreza Kazemi Yusheng Li Marco Solmi Muhammad Syafrudin Norma Latif Fitriyani Guillaume Fond Laurent Boyer Seung Won Lee Source Type: research

Development and content validity of the caregiver assisted transfer technique instrument
Assist Technol. 2024 Apr 26:1-9. doi: 10.1080/10400435.2024.2336334. Online ahead of print.ABSTRACTInformal caregivers often provide transfer assistance to individuals with disabilities; however, repeated transfers are associated with a high risk of musculoskeletal pain and injury, and training and education around transfers is minimal. The purpose of this study was to develop and assess the content validity of a new tool, the Caregiver Assisted Transfer Technique Instrument (CATT), which could be used to provide an objective indicator of transfer performance. Item importance, clarity, and appropriateness of responses were...
Source: Assistive Technology - April 26, 2024 Category: Rehabilitation Authors: Hailee R Kulich Diane Collins Brad E Dicianno Luci Leykum Lynn Worobey Rory Cooper Alicia M Koontz Source Type: research

Analgesic Mechanism of Dexmedetomidine and Esketamine in Rats with Spinal Cord Injury
CONCLUSIONS: Treatment using DEX combined with ESK improves the motor function, inhibits inflammation and astrocyte activity, and exerts analgesic effects on rats with SCI. These findings can serve as a reference for the selection of multi-modal analgesics.PMID:38665020 | DOI:10.24976/Discov.Med.202436183.67 (Source: Discovery Medicine)
Source: Discovery Medicine - April 26, 2024 Category: Research Authors: Huiting Zhao Zhuocheng Li Source Type: research

Musculoskeletal morbidity in adults with spinal cord injuries: A nationwide cohort study
CONCLUSION: SCI increases the risk of MSK morbidity. Lumbar SCI is associated with a higher incidence and risk of MSK morbidity than are cervical or thoracic SCIs.PMID:38669487 | DOI:10.3233/NRE-230263 (Source: NeuroRehabilitation)
Source: NeuroRehabilitation - April 26, 2024 Category: Rehabilitation Authors: Youngoh Bae Hohyun Jung Nakyung Shin Masoud Rahmati Raphael Udeh Abdolreza Kazemi Yusheng Li Marco Solmi Muhammad Syafrudin Norma Latif Fitriyani Guillaume Fond Laurent Boyer Seung Won Lee Source Type: research

Advanced MRI metrics improve the prediction of baseline disease severity for individuals with degenerative cervical myelopathy
Degenerative cervical myelopathy (DCM) is the most common form of atraumatic spinal cord injury globally. Degeneration of spinal discs, bony osteophyte growth and ligament pathology results in physical compression of the spinal cord contributing to damage of white matter tracts and grey matter cellular populations. This results in an insidious neurological and functional decline in patients which can lead to paralysis. Magnetic resonance imaging (MRI) confirms the diagnosis of DCM and is a prerequisite to surgical intervention, the only known treatment for this disorder. (Source: The Spine Journal)
Source: The Spine Journal - April 26, 2024 Category: Orthopaedics Authors: Abdul Al-Shawwa, Kalum Ost, David Anderson, Newton Cho, Nathan Evaniew, W. Bradley Jacobs, Allan R. Martin, Ranjeet Gaekwad, Saswati Tripathy, Jacques Bouchard, Steven Casha, Roger Cho, Stephen duPlessis, Peter Lewkonia, Fred Nicholls, Paul T. Salo, Alex Tags: Clinical Study Source Type: research