Organ distribution and early pathogenesis of Streptococcus equi subsp. zooepidemicus in swine
Comp Immunol Microbiol Infect Dis. 2023 Nov 18;104:102095. doi: 10.1016/j.cimid.2023.102095. Online ahead of print.ABSTRACTStreptococcus equi subsp. zooepidemicus is an emerging pathogen of pigs, resulting in high-mortality outbreaks of septicaemia and abortions. Here, we investigated the early pathogenesis of S. zooepidemicus in pigs following oronasal inoculation. Fourteen pigs were inoculated with live cultures of S. zooepidemicus ST-194, and monitored at 2,4, 8, and 24 h post-inoculation. Necropsies were performed to assess gross lesions and collect samples for bacterial culture and PCR analysis at each time point. Our...
Source: Comparative immunology, microbiology and infectious diseases. - November 21, 2023 Category: Allergy & Immunology Authors: Arthur Nery Finatto Sulove Koirala Fernanda Luiza Facioli J éssica Aparecida Barbosa Roman Nosach Matheus de Oliveira Costa Source Type: research

Progression of structural lung abnormality from 11 to 19 years in those born
Conclusion: We observed an improvement in total chest CT scores between 11 and 19-years, which was attenuated in participants with a more severe neonatal history. (Source: European Respiratory Journal)
Source: European Respiratory Journal - October 27, 2023 Category: Respiratory Medicine Authors: Wilson, A., Smith, E., Murray, C., Grdosic, J., Hemy, N., Hall, G., Simpson, S. Tags: Paediatric respiratory physiology and sleep Source Type: research

Genomic characterization and comparative genomic analysis of HS-associated Pasteurella multocida serotype B:2 strains from Pakistan
Haemorrhagic septicaemia (HS) is a highly fatal and predominant disease in livestock, particularly cattle and buffalo in the tropical regions of the world. Pasteurella multocida (P. multocida), serotypes B:2 and ... (Source: BMC Genomics)
Source: BMC Genomics - September 14, 2023 Category: Genetics & Stem Cells Authors: Sadia Mahboob, Nimat Ullah, Muhammad Farhan Ul Haque, Waqar Rauf, Mazhar Iqbal, Amjad Ali and Moazur Rahman Tags: Research Source Type: research

Species which may act as vectors or reservoirs of diseases covered by the Animal Health Law: Listed pathogens of fish
EFSA J. 2023 Aug 1;21(8):e08174. doi: 10.2903/j.efsa.2023.8174. eCollection 2023 Aug.ABSTRACTVector or reservoir species of five fish diseases listed in the Animal Health Law were identified, based on evidence generated through an extensive literature review (ELR), to support a possible updating of Regulation (EU) 2018/1882. Fish species on or in which highly polymorphic region-deleted infectious salmon anaemia virus (HPR∆ ISAV), Koi herpes virus (KHV), epizootic haematopoietic necrosis virus (EHNV), infectious haematopoietic necrosis virus (IHNV) or viral haemorrhagic septicaemia virus (VHSV) were detected, in the field...
Source: Herpes - August 3, 2023 Category: Infectious Diseases Authors: EFSA Panel on Animal Health and Welfare (AHAW) S øren Saxmose Nielsen Julio Alvarez Dominique Bicout Paolo Calistri Elisabetta Canali Julian Ashley Drewe Bruno Garin-Bastuji Jos é Louis Gonzales Rojas Christian Gortazar Smith Mette Herskin Virginie Mich Source Type: research

Development of an anti-infective urinary catheter composed of polyvinyl alcohol/sodium alginate/methylcellulose/polyethylene glycol by using a pressure-assisted 3D-printing technique
Int J Biol Macromol. 2023 Jul 29:126029. doi: 10.1016/j.ijbiomac.2023.126029. Online ahead of print.ABSTRACTCatheter-associated urinary tract infections (CAUTI) are a common complication associated with catheterization, leading to urosepsis, bacteriuria, and septicaemia. The present work focuses on 3D printing a urinary catheter with anti-infective properties using various concentrations of polyvinyl alcohol (PVA, e.g., 6-8 %), sodium alginate (NaAlg, e.g. 1-4 %), methylcellulose (MC, 5 %), polyethylene glycol (PEG, 5 %) impregnated with secnidazole, an antibiotic acting against Gram-negative bacteria. To produce suitable ...
Source: International Journal of Biological Macromolecules - July 31, 2023 Category: Biochemistry Authors: Menon Archana Durairajan Rubini Krishnan Priya Dharshini Bodethala Narayanan Vedha Hari Senthilganesh Jayasankari Durai Ramyadevi Weronika Gonciarz Agnieszka Doma ńska Marek Brzezi ński Paramasivam Nithyanand Source Type: research

Development of an anti-infective urinary catheter composed of polyvinyl alcohol/sodium alginate/methylcellulose/polyethylene glycol by using a pressure-assisted 3D-printing technique
Int J Biol Macromol. 2023 Jul 29:126029. doi: 10.1016/j.ijbiomac.2023.126029. Online ahead of print.ABSTRACTCatheter-associated urinary tract infections (CAUTI) are a common complication associated with catheterization, leading to urosepsis, bacteriuria, and septicaemia. The present work focuses on 3D printing a urinary catheter with anti-infective properties using various concentrations of polyvinyl alcohol (PVA, e.g., 6-8 %), sodium alginate (NaAlg, e.g. 1-4 %), methylcellulose (MC, 5 %), polyethylene glycol (PEG, 5 %) impregnated with secnidazole, an antibiotic acting against Gram-negative bacteria. To produce suitable ...
Source: International Journal of Biological Macromolecules - July 31, 2023 Category: Biochemistry Authors: Menon Archana Durairajan Rubini Krishnan Priya Dharshini Bodethala Narayanan Vedha Hari Senthilganesh Jayasankari Durai Ramyadevi Weronika Gonciarz Agnieszka Doma ńska Marek Brzezi ński Paramasivam Nithyanand Source Type: research

Evaluating the risk of infections under interleukin 23 and interleukin 17 inhibitors relative to tumour necrosis factor inhibitors - A population-based study
CONCLUSION: Compared with TNFi, IL-23i and IL-17i are associated with decreased risk of several infectious diseases. These agents might be preferred in patients with susceptibility to infections.PMID:37466275 | DOI:10.1111/jdv.19328 (Source: Herpes)
Source: Herpes - July 19, 2023 Category: Infectious Diseases Authors: Khalaf Kridin Henner Zirpel Noor Mruwat Ralf J Ludwig Diamant Thaci Source Type: research

Evaluating the risk of infections under interleukin 23 and interleukin 17 inhibitors relative to tumour necrosis factor inhibitors - A population-based study
CONCLUSION: Compared with TNFi, IL-23i and IL-17i are associated with decreased risk of several infectious diseases. These agents might be preferred in patients with susceptibility to infections.PMID:37466275 | DOI:10.1111/jdv.19328 (Source: Herpes)
Source: Herpes - July 19, 2023 Category: Infectious Diseases Authors: Khalaf Kridin Henner Zirpel Noor Mruwat Ralf J Ludwig Diamant Thaci Source Type: research

Immunochemical studies and gene cluster relationships of closely related O-antigens of Aeromonas hydrophila Pt679, Aeromonas popoffii A4, and Aeromonas sobria K928 strains classified into the PGO1 serogroup dominant in Polish aquaculture of carp and rainbow trout
Carbohydr Res. 2023 Jul 7;531:108896. doi: 10.1016/j.carres.2023.108896. Online ahead of print.ABSTRACTThe present study included three Aeromonas sp. strains isolated from fish tissues during Motile Aeromonas Infection/Motile Aeromonas Septicaemia disease outbreaks on commercial farms, i.e.: Aeromonas hydrophila Pt679 obtained from rainbow trout as well as Aeromonas popoffii A4 (formerly Aeromonas encheleia) and Aeromonas sobria K928 both isolated from carp, which were classified into the new provisional PGO1 serogroup prevailing among aeromonads in Polish aquaculture. The structure of the O-specific polysaccharides of A4 ...
Source: Carbohydrate Research - July 12, 2023 Category: Genetics & Stem Cells Authors: Maria Kurzylewska Anna Turska-Szewczuk Katarzyna Dworaczek Arkadiusz Bomba Dominika Drzewiecka Agnieszka P ękala-Safińska Source Type: research

Immunochemical studies and gene cluster relationships of closely related O-antigens of Aeromonas hydrophila Pt679, Aeromonas popoffii A4, and Aeromonas sobria K928 strains classified into the PGO1 serogroup dominant in Polish aquaculture of carp and rainbow trout
Carbohydr Res. 2023 Jul 7;531:108896. doi: 10.1016/j.carres.2023.108896. Online ahead of print.ABSTRACTThe present study included three Aeromonas sp. strains isolated from fish tissues during Motile Aeromonas Infection/Motile Aeromonas Septicaemia disease outbreaks on commercial farms, i.e.: Aeromonas hydrophila Pt679 obtained from rainbow trout as well as Aeromonas popoffii A4 (formerly Aeromonas encheleia) and Aeromonas sobria K928 both isolated from carp, which were classified into the new provisional PGO1 serogroup prevailing among aeromonads in Polish aquaculture. The structure of the O-specific polysaccharides of A4 ...
Source: Carbohydrate Research - July 12, 2023 Category: Genetics & Stem Cells Authors: Maria Kurzylewska Anna Turska-Szewczuk Katarzyna Dworaczek Arkadiusz Bomba Dominika Drzewiecka Agnieszka P ękala-Safińska Source Type: research

< em > Elizabethkingia meningosepticum < /em > infections with varied presentations and different antimicrobial susceptibility - A case series
We report three sporadic infections by Elizabethkingia meningosepticum from Government Medical College Kozhikode in Kerala state, South India over a period of three years. Two cases were commenced in the community in immunocompromised children beyond the newborn period, but both recovered promptly. Another was a hospital-acquired meningitis in a newborn baby who developed neurologic sequelae. In contrast to widespread antimicrobial resistance exhibited by this pathogen, there was good susceptibility to commonly used antimicrobials such as ampicillin, cefotaxime, piperacillin, ciprofloxacin, and vancomycin. Whilst ß lactam...
Source: Tropical Doctor - June 8, 2023 Category: Tropical Medicine Authors: Chakkiyar Krishnan Madathil Govindaraj Geeta Methele Pangat Balakrishnan Shabina Thaliyil Veettil Rajesh Aishwarya Raj Vellani Thamunnu Ajithkumar Source Type: research

< em > Elizabethkingia meningosepticum < /em > infections with varied presentations and different antimicrobial susceptibility - A case series
We report three sporadic infections by Elizabethkingia meningosepticum from Government Medical College Kozhikode in Kerala state, South India over a period of three years. Two cases were commenced in the community in immunocompromised children beyond the newborn period, but both recovered promptly. Another was a hospital-acquired meningitis in a newborn baby who developed neurologic sequelae. In contrast to widespread antimicrobial resistance exhibited by this pathogen, there was good susceptibility to commonly used antimicrobials such as ampicillin, cefotaxime, piperacillin, ciprofloxacin, and vancomycin. Whilst ß lactam...
Source: Tropical Doctor - June 8, 2023 Category: Tropical Medicine Authors: Chakkiyar Krishnan Madathil Govindaraj Geeta Methele Pangat Balakrishnan Shabina Thaliyil Veettil Rajesh Aishwarya Raj Vellani Thamunnu Ajithkumar Source Type: research

< em > Elizabethkingia meningosepticum < /em > infections with varied presentations and different antimicrobial susceptibility - A case series
We report three sporadic infections by Elizabethkingia meningosepticum from Government Medical College Kozhikode in Kerala state, South India over a period of three years. Two cases were commenced in the community in immunocompromised children beyond the newborn period, but both recovered promptly. Another was a hospital-acquired meningitis in a newborn baby who developed neurologic sequelae. In contrast to widespread antimicrobial resistance exhibited by this pathogen, there was good susceptibility to commonly used antimicrobials such as ampicillin, cefotaxime, piperacillin, ciprofloxacin, and vancomycin. Whilst ß lactam...
Source: Tropical Doctor - June 8, 2023 Category: Tropical Medicine Authors: Chakkiyar Krishnan Madathil Govindaraj Geeta Methele Pangat Balakrishnan Shabina Thaliyil Veettil Rajesh Aishwarya Raj Vellani Thamunnu Ajithkumar Source Type: research

< em > Elizabethkingia meningosepticum < /em > infections with varied presentations and different antimicrobial susceptibility - A case series
We report three sporadic infections by Elizabethkingia meningosepticum from Government Medical College Kozhikode in Kerala state, South India over a period of three years. Two cases were commenced in the community in immunocompromised children beyond the newborn period, but both recovered promptly. Another was a hospital-acquired meningitis in a newborn baby who developed neurologic sequelae. In contrast to widespread antimicrobial resistance exhibited by this pathogen, there was good susceptibility to commonly used antimicrobials such as ampicillin, cefotaxime, piperacillin, ciprofloxacin, and vancomycin. Whilst ß lactam...
Source: Tropical Doctor - June 8, 2023 Category: Tropical Medicine Authors: Chakkiyar Krishnan Madathil Govindaraj Geeta Methele Pangat Balakrishnan Shabina Thaliyil Veettil Rajesh Aishwarya Raj Vellani Thamunnu Ajithkumar Source Type: research

Structure and gene cluster annotation of the O-antigen of Aeromonas sobria strain K928 isolated from common carp and classified into the new Aeromonas PGO1 serogroup
Carbohydr Res. 2023 Apr 11;528:108809. doi: 10.1016/j.carres.2023.108809. Online ahead of print.ABSTRACTAeromonas sobria strain K928 was isolated from a common carp during a Motile Aeromonas Infection/Motile Aeromonas Septicaemia disease outbreak on a Polish fish farm and classified into the new provisional PGO1 serogroup. The lipopolysaccharide of A. sobria K928 was subjected to mild acid hydrolysis, and the O-specific polysaccharide, which was isolated by gel-permeation chromatography, was studied using sugar and methylation analyses and 1H and 13C NMR spectroscopy. The following structure of the branched O-specific poly...
Source: Carbohydrate Research - April 22, 2023 Category: Genetics & Stem Cells Authors: Maria Kurzylewska Arkadiusz Bomba Katarzyna Dworaczek Agnieszka P ękala-Safińska Anna Turska-Szewczuk Source Type: research