Treatment of end-stage peripheral artery disease by Neuromodulation
This study is a retrospective analysis based on a local prospective registry. Neuromodulation was performed there was: [1] no revascularisation option, [2) no septicaemia, [3) Rutherford stage 4-6. The primary endpoint of the study was limb salvage. Secondary endpoints were improvement in pain symptoms (assessed using a visual anlog scale/VAS) and improvement in walking distance.RESULTS: Limb salvage was reached in 30/34 patients (88%). Patients reported a significant reduction in pain on the 10-point VAS scale from baseline (median = 7.5, IQR = 7-8) to follow-up at 2 years (median = 0, IQR 0-2.75), p < 0.001. Walking d...
Source: Clinical Hemorheology and Microcirculation - April 25, 2022 Category: Hematology Authors: B Cucuruz R Kopp H Hampe-Hecht O Andercou W Schierling K Pfister M Koller T Noppeney Source Type: research
Treatment of end-stage peripheral artery disease by Neuromodulation
This study is a retrospective analysis based on a local prospective registry. Neuromodulation was performed there was: [1] no revascularisation option, [2) no septicaemia, [3) Rutherford stage 4-6. The primary endpoint of the study was limb salvage. Secondary endpoints were improvement in pain symptoms (assessed using a visual anlog scale/VAS) and improvement in walking distance.RESULTS: Limb salvage was reached in 30/34 patients (88%). Patients reported a significant reduction in pain on the 10-point VAS scale from baseline (median = 7.5, IQR = 7-8) to follow-up at 2 years (median = 0, IQR 0-2.75), p < 0.001. Walking d...
Source: Clinical Hemorheology and Microcirculation - April 25, 2022 Category: Hematology Authors: B Cucuruz R Kopp H Hampe-Hecht O Andercou W Schierling K Pfister M Koller T Noppeney Source Type: research
Treatment of end-stage peripheral artery disease by Neuromodulation
This study is a retrospective analysis based on a local prospective registry. Neuromodulation was performed there was: [1] no revascularisation option, [2) no septicaemia, [3) Rutherford stage 4-6. The primary endpoint of the study was limb salvage. Secondary endpoints were improvement in pain symptoms (assessed using a visual anlog scale/VAS) and improvement in walking distance.RESULTS: Limb salvage was reached in 30/34 patients (88%). Patients reported a significant reduction in pain on the 10-point VAS scale from baseline (median = 7.5, IQR = 7-8) to follow-up at 2 years (median = 0, IQR 0-2.75), p < 0.001. Walking d...
Source: Clinical Hemorheology and Microcirculation - April 25, 2022 Category: Hematology Authors: B Cucuruz R Kopp H Hampe-Hecht O Andercou W Schierling K Pfister M Koller T Noppeney Source Type: research
Treatment of end-stage peripheral artery disease by Neuromodulation
This study is a retrospective analysis based on a local prospective registry. Neuromodulation was performed there was: [1] no revascularisation option, [2) no septicaemia, [3) Rutherford stage 4-6. The primary endpoint of the study was limb salvage. Secondary endpoints were improvement in pain symptoms (assessed using a visual anlog scale/VAS) and improvement in walking distance.RESULTS: Limb salvage was reached in 30/34 patients (88%). Patients reported a significant reduction in pain on the 10-point VAS scale from baseline (median = 7.5, IQR = 7-8) to follow-up at 2 years (median = 0, IQR 0-2.75), p < 0.001. Walking d...
Source: Clinical Hemorheology and Microcirculation - April 25, 2022 Category: Hematology Authors: B Cucuruz R Kopp H Hampe-Hecht O Andercou W Schierling K Pfister M Koller T Noppeney Source Type: research
Treatment of end-stage peripheral artery disease by Neuromodulation
This study is a retrospective analysis based on a local prospective registry. Neuromodulation was performed there was: [1] no revascularisation option, [2) no septicaemia, [3) Rutherford stage 4-6. The primary endpoint of the study was limb salvage. Secondary endpoints were improvement in pain symptoms (assessed using a visual anlog scale/VAS) and improvement in walking distance.RESULTS: Limb salvage was reached in 30/34 patients (88%). Patients reported a significant reduction in pain on the 10-point VAS scale from baseline (median = 7.5, IQR = 7-8) to follow-up at 2 years (median = 0, IQR 0-2.75), p < 0.001. Walking d...
Source: Clinical Hemorheology and Microcirculation - April 25, 2022 Category: Hematology Authors: B Cucuruz R Kopp H Hampe-Hecht O Andercou W Schierling K Pfister M Koller T Noppeney Source Type: research
Treatment of end-stage peripheral artery disease by Neuromodulation
This study is a retrospective analysis based on a local prospective registry. Neuromodulation was performed there was: [1] no revascularisation option, [2) no septicaemia, [3) Rutherford stage 4-6. The primary endpoint of the study was limb salvage. Secondary endpoints were improvement in pain symptoms (assessed using a visual anlog scale/VAS) and improvement in walking distance.RESULTS: Limb salvage was reached in 30/34 patients (88%). Patients reported a significant reduction in pain on the 10-point VAS scale from baseline (median = 7.5, IQR = 7-8) to follow-up at 2 years (median = 0, IQR 0-2.75), p < 0.001. Walking d...
Source: Clinical Hemorheology and Microcirculation - April 25, 2022 Category: Hematology Authors: B Cucuruz R Kopp H Hampe-Hecht O Andercou W Schierling K Pfister M Koller T Noppeney Source Type: research
Treatment of end-stage peripheral artery disease by Neuromodulation
This study is a retrospective analysis based on a local prospective registry. Neuromodulation was performed there was: [1] no revascularisation option, [2) no septicaemia, [3) Rutherford stage 4-6. The primary endpoint of the study was limb salvage. Secondary endpoints were improvement in pain symptoms (assessed using a visual anlog scale/VAS) and improvement in walking distance.RESULTS: Limb salvage was reached in 30/34 patients (88%). Patients reported a significant reduction in pain on the 10-point VAS scale from baseline (median = 7.5, IQR = 7-8) to follow-up at 2 years (median = 0, IQR 0-2.75), p < 0.001. Walking d...
Source: Clinical Hemorheology and Microcirculation - April 25, 2022 Category: Hematology Authors: B Cucuruz R Kopp H Hampe-Hecht O Andercou W Schierling K Pfister M Koller T Noppeney Source Type: research
Treatment of end-stage peripheral artery disease by Neuromodulation
This study is a retrospective analysis based on a local prospective registry. Neuromodulation was performed there was: [1] no revascularisation option, [2) no septicaemia, [3) Rutherford stage 4-6. The primary endpoint of the study was limb salvage. Secondary endpoints were improvement in pain symptoms (assessed using a visual anlog scale/VAS) and improvement in walking distance.RESULTS: Limb salvage was reached in 30/34 patients (88%). Patients reported a significant reduction in pain on the 10-point VAS scale from baseline (median = 7.5, IQR = 7-8) to follow-up at 2 years (median = 0, IQR 0-2.75), p < 0.001. Walking d...
Source: Clinical Hemorheology and Microcirculation - April 25, 2022 Category: Hematology Authors: B Cucuruz R Kopp H Hampe-Hecht O Andercou W Schierling K Pfister M Koller T Noppeney Source Type: research
Treatment of end-stage peripheral artery disease by Neuromodulation
This study is a retrospective analysis based on a local prospective registry. Neuromodulation was performed there was: [1] no revascularisation option, [2) no septicaemia, [3) Rutherford stage 4-6. The primary endpoint of the study was limb salvage. Secondary endpoints were improvement in pain symptoms (assessed using a visual anlog scale/VAS) and improvement in walking distance.RESULTS: Limb salvage was reached in 30/34 patients (88%). Patients reported a significant reduction in pain on the 10-point VAS scale from baseline (median = 7.5, IQR = 7-8) to follow-up at 2 years (median = 0, IQR 0-2.75), p < 0.001. Walking d...
Source: Clinical Hemorheology and Microcirculation - April 25, 2022 Category: Hematology Authors: B Cucuruz R Kopp H Hampe-Hecht O Andercou W Schierling K Pfister M Koller T Noppeney Source Type: research
< em > Leclercia pneumoniae < /em > sp. nov., a bacterium isolated from clinical specimen in Leipzig, Germany
Int J Syst Evol Microbiol. 2022 Mar;72(3). doi: 10.1099/ijsem.0.005293.ABSTRACTStrain 49125T was isolated from an infant with pneumonia and septicaemia at the Leipzig University Hospital. Phenotypic and genomic traits were investigated. The strain's biochemical profile and its MALDI-TOF spectrogram did not differ from comparative samples of Leclercia adecarboxylata, thus far the sole member of the Leclercia species. A circular genome with a size of 4.4 Mbp and a G+C content of 55.0 mol% was reconstructed using hybrid Illumina and Nanopore sequencing. Phylogenetic analysis was based on 172 marker genes and validated using a...
Source: International Journal of Systematic and Evolutionary Microbiology - March 30, 2022 Category: Microbiology Authors: Mario H önemann Adrian Viehweger Nadine Dietze Julia Johnke Arne C Rodloff Source Type: research
Comparative genome analysis of Pasteurella multocida serogroup B:2 strains causing Haemorrhagic septicaemia (HS) in bovines
In this study, draft genomes of three virulent P. multocida serotype B:2 strains (NIVEDIPm32, NIVEDIPm34 and NIVEDIPm35) were analyzed following whole genome sequencing, assembly, annotation and compared them with existing global genomes (n=43) of bovine origin in the database. Three draft genomes of NIVEDIPm strains consisted of 40-52 contigs with GC content of ∼40.4%. The genome size and predicted genes content was ∼2.3 Mb and 2811- 2189, respectively. Besides, the presence of various mobile genetic elements, antimicrobial resistance genes and biofilm related genes suggested their vital roles in virulence; further, a...
Source: Gene - March 27, 2022 Category: Genetics & Stem Cells Authors: Awadhesh Prajapati Revanaiah Yogisharadhya Nihar Nalini Mohanty Suresh Kumar Mendem Azharuddin Nizamuddin Mohammed Mudassar Chanda Sathish Bhadravati Shivachandra Source Type: research
Septicaemia with deep venous thrombosis and necrotising pneumonia caused by acute community-acquired methicillin-resistant Staphylococcus aureus in an infant with a three-year follow-up: a case report
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is a common pathogen that usually causes bacteraemia, osteomyelitis, as well as skin and soft tissue infections. However, deep venous throm... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - February 24, 2022 Category: Infectious Diseases Authors: Mei Lu, Meijiao Fu, Yanhong Zhang, Tong Shen, Hui Xie and Dengli Liu Tags: Case report Source Type: research
Does social deprivation correlate with meningococcal MenACWY, Hib/MenC and 4CMenB/Meningococcal Group B vaccine uptake in Northern Ireland?
CONCLUSIONS: Within the last two decades, incidence of meningococcal disease has been on the decline. The introduction of meningococcal vaccines has contributed to this decrease and uptake of such vaccines should remain a public health priority to maintain the decline in meningococcal disease. Identifying contributing factors to low vaccine uptake, such as, the association between local deprivation and uptake of meningococcal vaccines, should be of public health importance and acknowledged by local governments and policy makers in their efforts to enhance vaccine uptake, both infant and teenage vaccination. There is a clea...
Source: The Ulster Medical Journal - February 16, 2022 Category: General Medicine Authors: Orlaith C Brennan John E Moore Beverley C Millar Source Type: research
Does social deprivation correlate with meningococcal MenACWY, Hib/MenC and 4CMenB/Meningococcal Group B vaccine uptake in Northern Ireland?
CONCLUSIONS: Within the last two decades, incidence of meningococcal disease has been on the decline. The introduction of meningococcal vaccines has contributed to this decrease and uptake of such vaccines should remain a public health priority to maintain the decline in meningococcal disease. Identifying contributing factors to low vaccine uptake, such as, the association between local deprivation and uptake of meningococcal vaccines, should be of public health importance and acknowledged by local governments and policy makers in their efforts to enhance vaccine uptake, both infant and teenage vaccination. There is a clea...
Source: The Ulster Medical Journal - February 16, 2022 Category: General Medicine Authors: Orlaith C Brennan John E Moore Beverley C Millar Source Type: research
Does social deprivation correlate with meningococcal MenACWY, Hib/MenC and 4CMenB/Meningococcal Group B vaccine uptake in Northern Ireland?
CONCLUSIONS: Within the last two decades, incidence of meningococcal disease has been on the decline. The introduction of meningococcal vaccines has contributed to this decrease and uptake of such vaccines should remain a public health priority to maintain the decline in meningococcal disease. Identifying contributing factors to low vaccine uptake, such as, the association between local deprivation and uptake of meningococcal vaccines, should be of public health importance and acknowledged by local governments and policy makers in their efforts to enhance vaccine uptake, both infant and teenage vaccination. There is a clea...
Source: The Ulster Medical Journal - February 16, 2022 Category: General Medicine Authors: Orlaith C Brennan John E Moore Beverley C Millar Source Type: research
