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A nose for trouble: ecotoxicological implications for climate change and disease in Saiga antelope (S. t. tatarica)
AbstractIn recent decades, Saiga antelope (Saiga t. tatarica) mass die-offs have become more common. The mass die-off of 2015 in central Kazakhstan, recorded 140,000 individual deaths across multiple herds. Previously, research has shown atmospheric humidity, the bacteriumPasteurella multocida serotype B, and resultant haemorrhagic septicaemia, were the primary cause. However, other synergistic factors may have impacted this process. Here we use a multivariate compositional data analysis (CoDA) approach to assess what other factors may have been involved. We show a pollutant linkage me chanism where relative humidity and...
Source: Environmental Geochemistry and Health - February 17, 2024 Category: Environmental Health Source Type: research

Circulating micronutrient levels and their association with sepsis susceptibility and severity: a Mendelian randomization study
Conclusion: Our study highlighted that zinc may emerges as a potential protective factor against severe sepsis-related death within 28 days, providing theoretical support for supplementing zinc in high-risk critically ill sepsis patients. In the future, larger-scale data are needed to validate our findings. (Source: Frontiers in Genetics)
Source: Frontiers in Genetics - February 16, 2024 Category: Genetics & Stem Cells Source Type: research

 Erysipelothrix amsterdamensis sp. nov., associated with mortalities among endangered seabirds
In this study, we genomically characterized 16 Erysipelothrix species isolates obtained from three Indian yellow-nosed albatross (Thalassarche carteri) chick carcasses in 2019. Histological analyses suggest that they died of bacterial septicaemia. Two isolates were sequenced using both Illumina short-read and MinION long-read approaches, which - following hybrid assembly - resulted in closed circular genomes. Mapping of Illumina reads from the remaining isolates to one of these new reference genomes revealed that all 16 isolates were closely related, with a maximum of 13 nucleotide differences distinguishing any pair of is...
Source: International Journal of Systematic and Evolutionary Microbiology - February 15, 2024 Category: Microbiology Authors: Jiadong Zhong Matej Medvecky J érémy Tornos Augustin Clessin Rozenn Le Net Hubert Gantelet Amandine Gamble Taya L Forde Thierry Boulinier Source Type: research

 STnc1280 , a trans-coding sRNA is involved in virulence modulation via targeting gldA mRNA in Salmonella Typhimurium
Conclusion. Combining the bioinformatic analysis, these findings suggested that STnc1280 may bind to the SD sequence of gldA mRNA, hindering the binding of ribosomes to gldA mRNA, thereby inhibiting the expression of GldA protein to modulate the virulence of STM.PMID:38353511 | DOI:10.1099/jmm.0.001804 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - February 14, 2024 Category: Microbiology Authors: Chengcheng Ning Na Li Lixia Wang Yun Guo Chunhui Ji Zhiyuan Li Yunxia Shang Xingxing Zhang Yaoqiang Sun Xiaoxing Huang Qingwen Leng Xuepeng Cai Qingling Meng Jun Qiao Source Type: research

Identification and characterisation of emerging fish pathogens Aeromonas veronii and Aeromonas hydrophila isolated from naturally infected Channa punctata
Antonie Van Leeuwenhoek. 2023 Dec 28;117(1):4. doi: 10.1007/s10482-023-01896-z.ABSTRACTNaturally infected Channa punctata exhibiting bacterial septicemic syndrome including ulcerations along with mortality records were collected from a fish farm in Assam during winter season (early November 2020 to early January 2021). The moribund fishes were subjected for bacterial isolation followed by identification of the bacteria. Two dominant emerging bacterial pathogens were identified as Aeromonas veronii (isolate ZooGURD-01) and Aeromonas hydrophila (isolate ZooGURD-05) by standard biochemical characterization and 16S rRNA and rp...
Source: Antonie van Leeuwenhoek - December 28, 2023 Category: Microbiology Authors: Rajdeep Das Kangkan Sarma Gayatree Hazarika Hrishikesh Choudhury Dandadhar Sarma Source Type: research

P095 Help stopping infant oral mutilation – a global child abuse and public health issue
All OMFS surgeons have been receiving updated knowledge of preventing Female Genital Mutilation (FGM) in regular mandatory Level 3 Child Safeguarding training. There is no teaching or awareness of children with IOM. Global mobilisation has resulted in an influx of migrant population to UK including children. IOM is a barbaric act involving the removal of healthy primary tooth buds with unhygienic, crude instruments without sterilisation or anaesthetic. Children undergoing IOM not only suffered from short and long term local dental abnormalities, but can also contract blood borne infection and death due to septicaemia. (Sou...
Source: The British Journal of Oral and Maxillofacial Surgery - December 1, 2023 Category: ENT & OMF Authors: Leo Cheng, Leo Cheng, Arthur Kemoli, Sharan Sidhu Source Type: research

Pathogenetic detection, retrospective and pathogenicity analysis of a fatal case of Vibrio vulnificus in Shenzhen, China
We report a 36-year-old male patient died ofV. vulnificus-induced septicaemia and multiple organ failure syndrome after oyster consumption at a restaurant. We isolated and identifiedV. vulnificus vv16015 from the patient ’s blood sample and antibiotic susceptibility tests indicated sensitivity to all 21 antibiotics. Oyster samples were subsequently collected from the restaurant’s supplier and three strains ofV. vulnificus were isolated. Whole genome sequencing and analysis revealed vv16015 to be distantly related to these strains and confirmed thatV. vulnificus contamination was present in the seafood of the restaurant...
Source: Gut Pathogens - November 25, 2023 Category: Microbiology Source Type: research