An analysis of Neisseria meningitidis strains causing meningococcal septic arthritis in England, and Wales: 2010-2020.
Neisseria meningitidis, a coloniser of the nasopharynx in humans, is the cause of invasive meningococcal disease (IMD); often characterised by severe systemic infection with relatively high morbidity and mortality (1). Meningococcal strains are classified into twelve capsular groups but, in England and Wales (E&W), groups B, C, W and Y cause the majority of invasive disease (2). Most IMD cases present as septicaemia, meningitis or both. Secondary localised infections such as myocarditis, endocarditis, pericarditis, pneumonia, and septic arthritis are less frequently observed (3). (Source: Journal of Infection)
Source: Journal of Infection - July 29, 2022 Category: Infectious Diseases Authors: George Gyamfi-Brobbey, Stephen A. Clark, Helen Campbell, Aiswarya Lekshmi, Sonia Ribeiro, Andrew Walker, Anna Mensah, Laura Willerton, Lloyd Walsh, Jay Lucidarme, Xilian Bai, Shamez N Ladhani, Saad Ahmed, Tom Walton, Ray Borrow Source Type: research
An analysis of Neisseria meningitidis strains causing meningococcal septic arthritis in England and Wales: 2010 –2020
Neisseria meningitidis, a coloniser of the nasopharynx in humans, is the cause of invasive meningococcal disease (IMD); often characterised by severe systemic infection with relatively high morbidity and mortality.1 Meningococcal strains are classified into twelve capsular groups but, in England and Wales (E&W), groups B, C, W and Y cause the majority of invasive disease.2 Most IMD cases present as septicaemia, meningitis or both. Secondary localised infections such as myocarditis, endocarditis, pericarditis, pneumonia, and septic arthritis are less frequently observed. (Source: Journal of Infection)
Source: Journal of Infection - July 29, 2022 Category: Infectious Diseases Authors: George Gyamfi-Brobbey, Stephen A. Clark, Helen Campbell, Aiswarya Lekshmi, Sonia Ribeiro, Andrew Walker, Anna Mensah, Laura Willerton, Lloyd Walsh, Jay Lucidarme, Xilian Bai, Shamez N Ladhani, Saad Ahmed, Tom Walton, Ray Borrow Source Type: research
Streptococcus pneumoniae interactions with the complement system
Host innate and adaptive immunity to infection with Streptococcus pneumoniae is critically dependent on the complement system, demonstrated by the high incidence of invasive S. pneumoniae infection in people with inherited deficiency of complement components. The complement system is activated by S. pneumoniae through multiple mechanisms. The classical complement pathway is activated by recognition of S. pneumoniae by C-reactive protein, serum amyloid P, C1q, SIGN-R1, or natural or acquired antibody. Some S. pneumoniae strains are also recognised by ficolins to activate the mannose binding lectin (MBL) activation pathway. ...
Source: Frontiers in cellular and infection microbiology - July 28, 2022 Category: Microbiology Source Type: research
Kinetics of the invasion of a non-phagocytic fish cell line, RTG-2 by Yersinia ruckeri serotype O1 biotype 1
Acta Vet Hung. 2022 Jun 20. doi: 10.1556/004.2022.00013. Online ahead of print.ABSTRACTYersiniosis, caused by the fish pathogen Yersinia ruckeri, is a serious bacterial septicaemia affecting mainly salmonids worldwide. The acute infection may result in high mortality without apparent external disease signs, while the chronic one causes moderate to considerable mortality. Survivors of yersiniosis outbreaks become carriers. Y. ruckeri is able to adhere to, and to invade, phagocytic and non-phagocytic fish cells by using unknown molecular mechanisms. The aim of this study was to describe the kinetics of cell invasion by Y. ru...
Source: Acta Veterinaria Hungarica - July 27, 2022 Category: Veterinary Research Authors: Daniel Padilla Bego ña Acosta Hernández Jos é Ramos Vivas Soraya D éniz Inmaculada Rosario Jos é Luís Martín Barrasa Andr és Sánchez Henao Freddy Silva Sergent Mar ía José Ramos Sosa Natalia Garc ía Álvarez Fernando Real Source Type: research
Kinetics of the invasion of a non-phagocytic fish cell line, RTG-2 by Yersinia ruckeri serotype O1 biotype 1
Acta Vet Hung. 2022 Jun 20. doi: 10.1556/004.2022.00013. Online ahead of print.ABSTRACTYersiniosis, caused by the fish pathogen Yersinia ruckeri, is a serious bacterial septicaemia affecting mainly salmonids worldwide. The acute infection may result in high mortality without apparent external disease signs, while the chronic one causes moderate to considerable mortality. Survivors of yersiniosis outbreaks become carriers. Y. ruckeri is able to adhere to, and to invade, phagocytic and non-phagocytic fish cells by using unknown molecular mechanisms. The aim of this study was to describe the kinetics of cell invasion by Y. ru...
Source: Acta Veterinaria Hungarica - July 27, 2022 Category: Veterinary Research Authors: Daniel Padilla Bego ña Acosta Hernández Jos é Ramos Vivas Soraya D éniz Inmaculada Rosario Jos é Luís Martín Barrasa Andr és Sánchez Henao Freddy Silva Sergent Mar ía José Ramos Sosa Natalia Garc ía Álvarez Fernando Real Source Type: research
Kinetics of the invasion of a non-phagocytic fish cell line, RTG-2 by Yersinia ruckeri serotype O1 biotype 1
Acta Vet Hung. 2022 Jun 20. doi: 10.1556/004.2022.00013. Online ahead of print.ABSTRACTYersiniosis, caused by the fish pathogen Yersinia ruckeri, is a serious bacterial septicaemia affecting mainly salmonids worldwide. The acute infection may result in high mortality without apparent external disease signs, while the chronic one causes moderate to considerable mortality. Survivors of yersiniosis outbreaks become carriers. Y. ruckeri is able to adhere to, and to invade, phagocytic and non-phagocytic fish cells by using unknown molecular mechanisms. The aim of this study was to describe the kinetics of cell invasion by Y. ru...
Source: Acta Veterinaria Hungarica - July 27, 2022 Category: Veterinary Research Authors: Daniel Padilla Bego ña Acosta Hernández Jos é Ramos Vivas Soraya D éniz Inmaculada Rosario Jos é Luís Martín Barrasa Andr és Sánchez Henao Freddy Silva Sergent Mar ía José Ramos Sosa Natalia Garc ía Álvarez Fernando Real Source Type: research
Kinetics of the invasion of a non-phagocytic fish cell line, RTG-2 by Yersinia ruckeri serotype O1 biotype 1
Acta Vet Hung. 2022 Jun 20. doi: 10.1556/004.2022.00013. Online ahead of print.ABSTRACTYersiniosis, caused by the fish pathogen Yersinia ruckeri, is a serious bacterial septicaemia affecting mainly salmonids worldwide. The acute infection may result in high mortality without apparent external disease signs, while the chronic one causes moderate to considerable mortality. Survivors of yersiniosis outbreaks become carriers. Y. ruckeri is able to adhere to, and to invade, phagocytic and non-phagocytic fish cells by using unknown molecular mechanisms. The aim of this study was to describe the kinetics of cell invasion by Y. ru...
Source: Acta Veterinaria Hungarica - July 27, 2022 Category: Veterinary Research Authors: Daniel Padilla Bego ña Acosta Hernández Jos é Ramos Vivas Soraya D éniz Inmaculada Rosario Jos é Luís Martín Barrasa Andr és Sánchez Henao Freddy Silva Sergent Mar ía José Ramos Sosa Natalia Garc ía Álvarez Fernando Real Source Type: research
Kinetics of the invasion of a non-phagocytic fish cell line, RTG-2 by Yersinia ruckeri serotype O1 biotype 1
Acta Vet Hung. 2022 Jun 20. doi: 10.1556/004.2022.00013. Online ahead of print.ABSTRACTYersiniosis, caused by the fish pathogen Yersinia ruckeri, is a serious bacterial septicaemia affecting mainly salmonids worldwide. The acute infection may result in high mortality without apparent external disease signs, while the chronic one causes moderate to considerable mortality. Survivors of yersiniosis outbreaks become carriers. Y. ruckeri is able to adhere to, and to invade, phagocytic and non-phagocytic fish cells by using unknown molecular mechanisms. The aim of this study was to describe the kinetics of cell invasion by Y. ru...
Source: Acta Veterinaria Hungarica - July 27, 2022 Category: Veterinary Research Authors: Daniel Padilla Bego ña Acosta Hernández Jos é Ramos Vivas Soraya D éniz Inmaculada Rosario Jos é Luís Martín Barrasa Andr és Sánchez Henao Freddy Silva Sergent Mar ía José Ramos Sosa Natalia Garc ía Álvarez Fernando Real Source Type: research
Kinetics of the invasion of a non-phagocytic fish cell line, RTG-2 by Yersinia ruckeri serotype O1 biotype 1
Acta Vet Hung. 2022 Jun 20. doi: 10.1556/004.2022.00013. Online ahead of print.ABSTRACTYersiniosis, caused by the fish pathogen Yersinia ruckeri, is a serious bacterial septicaemia affecting mainly salmonids worldwide. The acute infection may result in high mortality without apparent external disease signs, while the chronic one causes moderate to considerable mortality. Survivors of yersiniosis outbreaks become carriers. Y. ruckeri is able to adhere to, and to invade, phagocytic and non-phagocytic fish cells by using unknown molecular mechanisms. The aim of this study was to describe the kinetics of cell invasion by Y. ru...
Source: Acta Veterinaria Hungarica - July 27, 2022 Category: Veterinary Research Authors: Daniel Padilla Bego ña Acosta Hernández Jos é Ramos Vivas Soraya D éniz Inmaculada Rosario Jos é Luís Martín Barrasa Andr és Sánchez Henao Freddy Silva Sergent Mar ía José Ramos Sosa Natalia Garc ía Álvarez Fernando Real Source Type: research
Kinetics of the invasion of a non-phagocytic fish cell line, RTG-2 by Yersinia ruckeri serotype O1 biotype 1
Acta Vet Hung. 2022 Jun 20. doi: 10.1556/004.2022.00013. Online ahead of print.ABSTRACTYersiniosis, caused by the fish pathogen Yersinia ruckeri, is a serious bacterial septicaemia affecting mainly salmonids worldwide. The acute infection may result in high mortality without apparent external disease signs, while the chronic one causes moderate to considerable mortality. Survivors of yersiniosis outbreaks become carriers. Y. ruckeri is able to adhere to, and to invade, phagocytic and non-phagocytic fish cells by using unknown molecular mechanisms. The aim of this study was to describe the kinetics of cell invasion by Y. ru...
Source: Acta Veterinaria Hungarica - July 27, 2022 Category: Veterinary Research Authors: Daniel Padilla Bego ña Acosta Hernández Jos é Ramos Vivas Soraya D éniz Inmaculada Rosario Jos é Luís Martín Barrasa Andr és Sánchez Henao Freddy Silva Sergent Mar ía José Ramos Sosa Natalia Garc ía Álvarez Fernando Real Source Type: research
Kinetics of the invasion of a non-phagocytic fish cell line, RTG-2 by Yersinia ruckeri serotype O1 biotype 1
Acta Vet Hung. 2022 Jun 20. doi: 10.1556/004.2022.00013. Online ahead of print.ABSTRACTYersiniosis, caused by the fish pathogen Yersinia ruckeri, is a serious bacterial septicaemia affecting mainly salmonids worldwide. The acute infection may result in high mortality without apparent external disease signs, while the chronic one causes moderate to considerable mortality. Survivors of yersiniosis outbreaks become carriers. Y. ruckeri is able to adhere to, and to invade, phagocytic and non-phagocytic fish cells by using unknown molecular mechanisms. The aim of this study was to describe the kinetics of cell invasion by Y. ru...
Source: Acta Veterinaria Hungarica - July 27, 2022 Category: Veterinary Research Authors: Daniel Padilla Bego ña Acosta Hernández Jos é Ramos Vivas Soraya D éniz Inmaculada Rosario Jos é Luís Martín Barrasa Andr és Sánchez Henao Freddy Silva Sergent Mar ía José Ramos Sosa Natalia Garc ía Álvarez Fernando Real Source Type: research
Kinetics of the invasion of a non-phagocytic fish cell line, RTG-2 by Yersinia ruckeri serotype O1 biotype 1
Acta Vet Hung. 2022 Jun 20. doi: 10.1556/004.2022.00013. Online ahead of print.ABSTRACTYersiniosis, caused by the fish pathogen Yersinia ruckeri, is a serious bacterial septicaemia affecting mainly salmonids worldwide. The acute infection may result in high mortality without apparent external disease signs, while the chronic one causes moderate to considerable mortality. Survivors of yersiniosis outbreaks become carriers. Y. ruckeri is able to adhere to, and to invade, phagocytic and non-phagocytic fish cells by using unknown molecular mechanisms. The aim of this study was to describe the kinetics of cell invasion by Y. ru...
Source: Acta Veterinaria Hungarica - July 27, 2022 Category: Veterinary Research Authors: Daniel Padilla Bego ña Acosta Hernández Jos é Ramos Vivas Soraya D éniz Inmaculada Rosario Jos é Luís Martín Barrasa Andr és Sánchez Henao Freddy Silva Sergent Mar ía José Ramos Sosa Natalia Garc ía Álvarez Fernando Real Source Type: research
Kinetics of the invasion of a non-phagocytic fish cell line, RTG-2 by Yersinia ruckeri serotype O1 biotype 1
Acta Vet Hung. 2022 Jun 20. doi: 10.1556/004.2022.00013. Online ahead of print.ABSTRACTYersiniosis, caused by the fish pathogen Yersinia ruckeri, is a serious bacterial septicaemia affecting mainly salmonids worldwide. The acute infection may result in high mortality without apparent external disease signs, while the chronic one causes moderate to considerable mortality. Survivors of yersiniosis outbreaks become carriers. Y. ruckeri is able to adhere to, and to invade, phagocytic and non-phagocytic fish cells by using unknown molecular mechanisms. The aim of this study was to describe the kinetics of cell invasion by Y. ru...
Source: Acta Veterinaria Hungarica - July 27, 2022 Category: Veterinary Research Authors: Daniel Padilla Bego ña Acosta Hernández Jos é Ramos Vivas Soraya D éniz Inmaculada Rosario Jos é Luís Martín Barrasa Andr és Sánchez Henao Freddy Silva Sergent Mar ía José Ramos Sosa Natalia Garc ía Álvarez Fernando Real Source Type: research
Kinetics of the invasion of a non-phagocytic fish cell line, RTG-2 by Yersinia ruckeri serotype O1 biotype 1
Acta Vet Hung. 2022 Jun 20. doi: 10.1556/004.2022.00013. Online ahead of print.ABSTRACTYersiniosis, caused by the fish pathogen Yersinia ruckeri, is a serious bacterial septicaemia affecting mainly salmonids worldwide. The acute infection may result in high mortality without apparent external disease signs, while the chronic one causes moderate to considerable mortality. Survivors of yersiniosis outbreaks become carriers. Y. ruckeri is able to adhere to, and to invade, phagocytic and non-phagocytic fish cells by using unknown molecular mechanisms. The aim of this study was to describe the kinetics of cell invasion by Y. ru...
Source: Acta Veterinaria Hungarica - July 27, 2022 Category: Veterinary Research Authors: Daniel Padilla Bego ña Acosta Hernández Jos é Ramos Vivas Soraya D éniz Inmaculada Rosario Jos é Luís Martín Barrasa Andr és Sánchez Henao Freddy Silva Sergent Mar ía José Ramos Sosa Natalia Garc ía Álvarez Fernando Real Source Type: research
Kinetics of the invasion of a non-phagocytic fish cell line, RTG-2 by Yersinia ruckeri serotype O1 biotype 1
Acta Vet Hung. 2022 Jun 20. doi: 10.1556/004.2022.00013. Online ahead of print.ABSTRACTYersiniosis, caused by the fish pathogen Yersinia ruckeri, is a serious bacterial septicaemia affecting mainly salmonids worldwide. The acute infection may result in high mortality without apparent external disease signs, while the chronic one causes moderate to considerable mortality. Survivors of yersiniosis outbreaks become carriers. Y. ruckeri is able to adhere to, and to invade, phagocytic and non-phagocytic fish cells by using unknown molecular mechanisms. The aim of this study was to describe the kinetics of cell invasion by Y. ru...
Source: Acta Veterinaria Hungarica - July 27, 2022 Category: Veterinary Research Authors: Daniel Padilla Bego ña Acosta Hernández Jos é Ramos Vivas Soraya D éniz Inmaculada Rosario Jos é Luís Martín Barrasa Andr és Sánchez Henao Freddy Silva Sergent Mar ía José Ramos Sosa Natalia Garc ía Álvarez Fernando Real Source Type: research
