Population incidence and associated mortality of urinary tract infection in people living with dementia
Urinary tract infections (UTIs) frequently cause hospitalisation and death in people living with dementia (PLWD). We examine UTI incidence and associated mortality among PLWD relative to matched controls and people with diabetes and investigate whether delayed or withheld treatment further impacts mortality. (Source: Journal of Infection)
Source: Journal of Infection - April 26, 2024 Category: Infectious Diseases Authors: Helen Lai, Magdalena Kolanko, Lucia M Li, Megan E Parkinson, Niall J Bourke, Neil SN Graham, Michael CB David, Emma-Jane Mallas, Bowen Su, Sarah Daniels, Danielle Wilson, Mara Golemme, Claire Norman, Kirsten Jensen, Raphaella Jackson, Martin Tran, Paul S Source Type: research

Corrigendum to: “People living with HIV who have poor immune status are a key population for SARS-CoV-2 prevention” Journal of Infection, Volume 88, Issue 3, March 2024, 106122
The authors regret that the originally published acknowledgements section was missing some information. Please see the correct version below: (Source: Journal of Infection)
Source: Journal of Infection - April 24, 2024 Category: Infectious Diseases Authors: Jie Zhou, Liuyan Lan, Sufang Ai, Jianyan Lin, Ningmei Liu, Yulan Xie, Ping Cui, Hao Liang, Li Ye, Jiegang Huang, Zhiman Xie Source Type: research

Temporal variations in the serogroup distribution of invasive meningococcal disease in Quebec, Canada, due to emerging unique clade of serogroup Y strain belonging to the Sequence Type-23 clonal complex.
To identify recent trends in invasive meningococcal diseases (IMD) in Quebec, Canada, with a focus on MenY cases and MenY strains. (Source: Journal of Infection)
Source: Journal of Infection - April 23, 2024 Category: Infectious Diseases Authors: Raymond S.W. Tsang, Genevieve Deceuninck, Courtney Meilleur, Jianwei Zhou, Brigitte Lefebvre, Philippe De Wals Tags: Bacteria and Bacterial Diseases Source Type: research

Heterologous and BNT162b2 boosters are more effective than non-mRNA homologous boosters for Omicron
Dear Editor, (Source: Journal of Infection)
Source: Journal of Infection - April 23, 2024 Category: Infectious Diseases Authors: Angel Paternina-Caicedo, David Santiago Quevedo, Diana Sof ía Ríos, Diane Moyano, Nelson Alvis-Guzmán, Nelson Rafael Alviz-Zakzuk, Fernando Salcedo, Javier Ramírez-Suarez, Adrian D Smith, Fernando De la Hoz-Restrepo Source Type: research

Molecular Rapid Diagnostic Testing for Bloodstream Infections: Nanopore Targeted Sequencing with Pathogen-Specific Primers
Nanopore sequencing, known for real-time analysis, shows promise for rapid clinical infection diagnosis but lacks effective assays for bloodstream infections (BSIs). (Source: Journal of Infection)
Source: Journal of Infection - April 23, 2024 Category: Infectious Diseases Authors: Dongsheng Han, Fei Yu, Dan Zhang, Juan Hu, Xuan Zhang, Dairong Xiang, Bin Lou, Yu Chen, Shufa Zheng Source Type: research

Understanding the potential role of whole genome sequencing (WGS) in managing patients with gonorrhoea: A systematic review of WGS use on human pathogens in individual patient care
The utility of whole genome sequencing (WGS) to inform sexually transmitted infection (STI) patient management is unclear. Timely WGS data might support clinical management of STIs by characterising epidemiological links and antimicrobial resistance profiles. We conducted a systematic review of clinical application of WGS to any human pathogen that may be transposable to gonorrhoea. (Source: Journal of Infection)
Source: Journal of Infection - April 23, 2024 Category: Infectious Diseases Authors: Roeann Osman, Emily Dema, Alexandra David, Gwenda Hughes, Nigel Field, Michelle Cole, Xavier Didelot, John Saunders Source Type: research

No evidence of difference in mortality with amoxicillin versus co-amoxiclav for hospital treatment of community-acquired pneumonia
Current guidelines recommend broad-spectrum antibiotics for high-severity community-acquired pneumonia (CAP), potentially contributing to antimicrobial resistance (AMR). We aim to compare outcomes in CAP patients treated with amoxicillin (narrow-spectrum) versus co-amoxiclav (broad-spectrum), to understand if narrow-spectrum antibiotics could be used more widely. (Source: Journal of Infection)
Source: Journal of Infection - April 23, 2024 Category: Infectious Diseases Authors: Jia Wei, Aashna Uppal, Christy Nganjimi, Hermione Warr, Yasin Ibrahim, Qingze Gu, Hang Yuan, Najib M Rahman, Nicola Jones, A Sarah Walker, David W Eyre Source Type: research

Risk factors for Nocardia infection among allogeneic hematopoietic cell transplant recipients: A case-control study of the Infectious Diseases Working Party of the European Society for Blood and Marrow Transplantation
Nocardiosis is a rare but life-threatening infection after hematopoietic cell transplantation (HCT). We aimed at identifying risk factors for nocardiosis after allogeneic HCT and clarifying the effect of trimethoprim-sulfamethoxazole prophylaxis on its occurrence. (Source: Journal of Infection)
Source: Journal of Infection - April 23, 2024 Category: Infectious Diseases Authors: Julien De Greef, Dina Averbuch, Laura Tondeur, Am élie Duréault, Tsila Zuckerman, Xavier Roussel, Christine Robin, Alienor Xhaard, Simona Pagliuca, Yves Beguin, Carmen Botella-Garcia, Nina Khanna, Amandine Le Bourgeois, Jens Van Praet, Aloysius Ho, Nico Source Type: research

Infections in preschool and school-aged children are driving the recent rise in pertussis in China
Dear editor, (Source: Journal of Infection)
Source: Journal of Infection - April 23, 2024 Category: Infectious Diseases Authors: Yahong Hu, Mengyang Guo, Kaihu Yao Source Type: research

Integrated single-cell transcriptome and T cell receptor profiling reveals defects of T cell exhaustion in pulmonary tuberculosis
Tuberculosis-affected lungs with chronic inflammation harbor abundant immunosuppressive immune cells but the nature of such inflammation is unclear. Dysfunction in T cell exhaustion, while implicated in chronic inflammatory diseases, remains unexplored in tuberculosis. Given that immunotherapy targeting exhaustion checkpoints exacerbates tuberculosis, we speculate that T cell exhaustion is dysfunctional in tuberculosis. Using integrated single-cell RNA sequencing and T cell receptor profiling we reported defects in exhaustion responses within inflamed tuberculosis-affected lungs. (Source: Journal of Infection)
Source: Journal of Infection - April 18, 2024 Category: Infectious Diseases Authors: Zilu Wen, Lin Wang, Hui Ma, Leilei Li, Laiyi Wan, Lei Shi, Hongwei Li, Hui Chen, Wentao Hao, Shu Song, Qinghua Xue, Yutong Wei, Feng Li, Jianqing Xu, Shulin Zhang, Ka-Wing Wong, Yanzheng Song Tags: Bacteria and Bacterial Diseases Source Type: research

Performance of the Galactomannan Test for the Diagnosis of Invasive Pulmonary Aspergillosis using Non-invasive Proximal Airway Samples
To diagnose invasive pulmonary aspergillosis (IPA), galactomannan (GM) detection in serum or bronchoalveolar lavage fluid (BALF) is widely used. However, the utility of proximal airway GM test (from induced sputum or tracheal aspirate) has not been well elucidated. (Source: Journal of Infection)
Source: Journal of Infection - April 17, 2024 Category: Infectious Diseases Authors: June Young Chun, Sahng-Joon Jeong, Sinae Kim, Soyoung Choi, Jong Hyuk Lee, Hyun Sung Chung, Seungman Park, Hyewon Lee, Hyae Young Kim, Bin Hwangbo, Young Ju Choi Source Type: research

The Potential Value of a Quantitative PCR Assay for Assessing Respiratory Samples in Approaching a Laboratory Diagnosis of Pulmonary Mucormycosis
Dear Editor, (Source: Journal of Infection)
Source: Journal of Infection - April 17, 2024 Category: Infectious Diseases Authors: Ya-Ping Chen, Cong-Tat Cia, Ya-Ting Hsu, Po-Lin Chen, Tsai-Yun Chen, Jen-Chieh Lee, Sin-Syue Li, Ming-I Hsieh, Hsuan-Chen Wang, Chi-Jung Wu Tags: Letter to the Editor Source Type: research

Distinct patterns of vital sign and inflammatory marker responses in adults with suspected bloodstream infection
To identify patterns in inflammatory marker and vital sign responses in adult with suspected bloodstream infection (BSI) and define expected trends in normal recovery. (Source: Journal of Infection)
Source: Journal of Infection - April 8, 2024 Category: Infectious Diseases Authors: Qingze Gu, Jia Wei, Chang Ho Yoon, Kevin Yuan, Nicola Jones, Andrew Brent, Martin Llewelyn, Tim EA Peto, Koen B Pouwels, David W Eyre, A Sarah Walker Source Type: research

Viruses associated with measles-like illnesses in Uganda
In this study, we investigated the causes of measles-like illnesses (MLI) in the Uganda national surveillance programme in order to inform diagnostic assay selection and vaccination strategies. (Source: Journal of Infection)
Source: Journal of Infection - April 6, 2024 Category: Infectious Diseases Authors: Prossy Namuwulya, Shirin Ashraf, Marc Niebel, Alfred Ssekagiri, Phionah Tushabe, Proscovia Kakooza, Lily Tong, Henry Bukenya, Hanna Jerome, Chris Davis, Molly Birungi, Irene Turyahabwe, Arnold Mugaga, James Peter Eliku, Aine Francis, Lucy Nakabazzi, Fred Source Type: research

Genomic evolution of human respiratory syncytial virus during a decade (2013-2023): bridging the path to monoclonal antibody surveillance
This study investigated the prevalence, genetic diversity, and evolution of human respiratory syncytial virus (HRSV) in Barcelona from 2013 to 2023. (Source: Journal of Infection)
Source: Journal of Infection - April 5, 2024 Category: Infectious Diseases Authors: Maria Pi ñana, Alejandra González-Sánchez, Cristina Andrés, Jorgina Vila, Anna Creus-Costa, Ignasi Prats-Méndez, Maria Arnedo-Muñoz, Narcís Saubi, Juliana Esperalba, Ariadna Rando, Patricia Nadal-Baron, Josep Quer, Juan José González-López, Pere Source Type: research