A novel quantitative urine LAM antigen strip for point-of-care tuberculosis diagnosis in non-HIV adults
We read with interest the systematic review by Ashar et al. in which the implementation of lateral flow lipoarabinomannan (LAM)-based tuberculosis (TB) testing among HIV-positive inpatients is recommended.1  Detecting urinary LAM may represent a promising approach to address the gap in TB diagnosis,2 which is rapid, economical, and available at point-of-care (POC) and utilizes non-sputum samples to cater to populations who have difficulty producing diagnostic sputum samples.1,3 However, limited sens itivity has impeded its widespread adoption. (Source: Journal of Infection)
Source: Journal of Infection - November 28, 2023 Category: Infectious Diseases Authors: Zhen Huang, Huan Huang, Jing Hu, Lu Xia, Xuhui Liu, Rong Qu, Xiaolin Huang, Yang Yang, Kang Wu, Ruiqing Ma, Jinchuan Xu, Zhenyan Chen, Yuhao Wu, Juan Yang, Yong Fang, Jianfeng Zeng, Weihua Lai, Guodong Sui, Wei Sha, Yonghua Xiong, Shuihua Lu, Xiao-Yong Fa Tags: Letter to the Editor Source Type: research

A novel quantitative urine LAM strip for point-of-care tuberculosis diagnosis in non-HIV adults
We read with interest the systematic review by Ashar et al. in which the implementation of lateral flow lipoarabinomannan (LAM)-based tuberculosis (TB) testing among HIV-positive inpatients is recommended1. Detecting urinary LAM may represent a promising approach to address the gap in TB diagnosis2, which is rapid, economical, and available at point-of-care (POC) and utilizes non-sputum samples to cater to populations who have difficulty producing diagnostic sputum samples1,3. However, limited sensitivity has impeded its widespread adoption3. (Source: Journal of Infection)
Source: Journal of Infection - November 28, 2023 Category: Infectious Diseases Authors: Zhen Huang, Huan Huang, Jing Hu, Lu Xia, Xuhui Liu, Rong Qu, Xiaolin Huang, Yang Yang, Kang Wu, Ruiqing Ma, Jinchuan Xu, Zhenyan Chen, Yuhao Wu, Juan Yang, Yong Fang, Jianfeng Zeng, Weihua Lai, Guodong Sui, Wei Sha, Yonghua Xiong, Shuihua Lu, Xiao-Yong Fa Tags: Letter to the Editor Source Type: research

Antibiotic use and outcome in patients with negative blood cultures, a new target population for antimicrobial stewardship interventions: a prospective multicentre cohort (NO-BACT).
To evaluate the appropriateness of antimicrobial treatment and the risk factors for mortality in patients with negative blood cultures (BC), in order to evaluate whether this population would be a suitable target for antimicrobial stewardship (AMS) interventions. (Source: Journal of Infection)
Source: Journal of Infection - November 28, 2023 Category: Infectious Diseases Authors: Jose Antonio Gir ón-Ortega, Raquel Fernández-Guerrero, Montserrat Montes de Oca Arjona, Fátima Galán-Sanchez, Galadriel Pellejero Sagastizábal, Elena Morte Romea, Marina de Cueto, Margarita Beltrán Garcia, Zaira Palacios-Baena, Silvia Jiménez Jorge Source Type: research

Editorial Board
(Source: Journal of Infection)
Source: Journal of Infection - November 24, 2023 Category: Infectious Diseases Source Type: research

Demystifying the global outbreak of severe acute hepatitis of unknown aetiology in children: a systematic review and meta-analysis
The sudden outbreak of severe acute hepatitis of unknown aetiology (SAHUA) in the first half of 2022 affected more than 1010 children in 35 countries worldwide. Dire clinical outcomes such as acute liver failure necessitating transplantation, neurological symptoms, long-term sequelae, and death highlight the need to determine the pathogenesis of this condition. Hypotheses on the aetiology include adenovirus and SARS-CoV-2 infections and an aberrant immune response to multiple pathogen exposure following lifting of lockdown measures but further investigation is required to reach an informed consensus. (Source: Journal of Infection)
Source: Journal of Infection - November 23, 2023 Category: Infectious Diseases Authors: Julie Phan, Guy D. Eslick, Elizabeth J. Elliott Source Type: research

A new era of Open Access for the Journal of Infection
January 2024, is a watershed moment for the British Infection Association and the Journal of Infection, a title which is owned by the BIA and published by Elsevier. Since its inception in 1979, the Journal has been a subscription journal, with income mostly derived from institutional and personal subscriptions. Any profits in the form of royalties have been used by the Association for academic activities, including educational grants, research grants, and meetings. The advantage of the subscription model has been a reliable income supporting the production of the Journal. (Source: Journal of Infection)
Source: Journal of Infection - November 23, 2023 Category: Infectious Diseases Authors: Robert C Read, David G Partridge Tags: Editorial Source Type: research

Low-grade endotoxemia is associated with cardiovascular events in community-acquired pneumonia
Community-acquired pneumonia (CAP) is associated with low-grade endotoxemia but its relationship with cardiovascular events (CVE) has not been investigated. (Source: Journal of Infection)
Source: Journal of Infection - November 22, 2023 Category: Infectious Diseases Authors: Roberto Cangemi, Roberto Carnevale, Cristina Nocella, Camilla Calvieri, Simona Bartimoccia, Giacomo Frati, Pasquale Pignatelli, Vittorio Picchio, Francesco Violi Source Type: research

Low grade endotoxemia is associated with cardiovascular events in community-acquired pneumonia
Community-acquired pneumonia (CAP) is associated with low-grade endotoxemia but its relationship with cardiovascular events (CVE) has not been investigated. (Source: Journal of Infection)
Source: Journal of Infection - November 22, 2023 Category: Infectious Diseases Authors: Roberto Cangemi, Roberto Carnevale, Cristina Nocella, Camilla Calvieri, Simona Bartimoccia, Giacomo Frati, Pasquale Pignatelli, Vittorio Picchio, Francesco Violi Source Type: research

Increasing incidence of community-acquired adult group A streptococcal meningitis in the Netherlands
Dear Editor, (Source: Journal of Infection)
Source: Journal of Infection - November 21, 2023 Category: Infectious Diseases Authors: Evelien H.G.M. Drost, Nora Chekrouni, Thijs M. van Soest, Kim Schipper, Nina M. van Sorge, Matthijs C. Brouwer, Diederik van de Beek Tags: Letter to the Editor Source Type: research

Increasing incidence of community-acquired adult group a streptococcal meningtis in the netherlands
Dear editor, (Source: Journal of Infection)
Source: Journal of Infection - November 21, 2023 Category: Infectious Diseases Authors: Evelien H.G.M. Drost, Nora Chekrouni, Thijs M. van Soest, Kim Schipper, Nina M. van Sorge, Matthijs C. Brouwer, Diederik van de Beek Tags: Letter to the Editor Source Type: research

A decade of Campylobacter and Campylobacter bacteraemias in a district general hospital and the surrounding London and South East region, England
Campylobacter bacteraemia is a rare complication of the most common bacterial gastrointestinal infection but is associated with significant morbidity and mortality. There is limited data describing current trends in surveillance and antimicrobial resistance for the Campylobacter strains involved. At the Epsom and St Helier ’s University Hospital (ESTH), we noted a marked increase in Campylobacter bacteraemia infections in 2021. (Source: Journal of Infection)
Source: Journal of Infection - November 20, 2023 Category: Infectious Diseases Authors: Alice Graham, Lois Hawkins, Sooria Balasegaram, Subha Narasimhan, John Wain, John Clarke, Rohini Manuel Source Type: research

Machine learning-based colistin resistance marker screening and phenotype prediction in Escherichia coli from whole genome sequencing data
Dear Editor, (Source: Journal of Infection)
Source: Journal of Infection - November 20, 2023 Category: Infectious Diseases Authors: Yingxin Tian, Di Zhang, Fangyuan Chen, Guanhua Rao, Ying Zhang Tags: Letter to the Editor Source Type: research

Efficacy of SIGMAR1-based therapy in the early treatment of confirmed mild symptomatic COVID-19 patients
Dear Editor, (Source: Journal of Infection)
Source: Journal of Infection - November 20, 2023 Category: Infectious Diseases Authors: Santiago Grau, Jos é Miguel Vela, Alba Gurt, Jaime Barceló-Vidal, Fabiola Ojeda, Iago López, Laura Gómez-García, Mabel Loza, Elena Martín-García, Rafael Maldonado, Jordi Monfort, SIGMA Group Source Type: research

How do successive vaccinations and SARS-CoV-2 infections impact humoral immunity dynamics: an 18-month longitudinal study
Dear editor, (Source: Journal of Infection)
Source: Journal of Infection - November 17, 2023 Category: Infectious Diseases Authors: A.N. Diep, J. Schyns, C. Gourzones, E. Goffin, I. Papadopoulos, S. Moges, F. Minner, O. Ek, G. Bonhomme, M. Paridans, N. Gillain, E. Husson, M. Garigliany, G. Darcis, C. Saegerman, D. Desmecht, M. Guillaume, A.F. Donneau, F. Bureau, L. Gillet Source Type: research

Identification of a Novel HIV-1 Circulating Recombinant Form CRF157_A6C in Primorsky Territory, Russia
Dear editor, (Source: Journal of Infection)
Source: Journal of Infection - November 17, 2023 Category: Infectious Diseases Authors: Maksim R Halikov, Vasily E Ekushov, Alexei V Totmenin, Natalya M Gashnikova, Mariya E Antonets, Tatyana V Tregubchak, Lidiia P Skliar, Natalia P Solovyova, Irina S Gorelova, Svetlana N Beniova Source Type: research