Intranasal immunization with outer membrane vesicles (OMV) protects against airway colonization and systemic infection with Acinetobacter baumannii
The multidrug-resistant bacteria Acinetobacter baumannii is a major cause of hospital-associated infection; a vaccine could significantly reduce this burden. The aim was to develop a clinically relevant model of A. baumannii respiratory tract infection and to test the impact of different immunization routes on protective immunity provided by an outer membrane vesicle (OMV) vaccine. (Source: Journal of Infection)
Source: Journal of Infection - February 27, 2023 Category: Infectious Diseases Authors: Sophie L. Higham, Stephen Baker, Katie E. Flight, Aishwarya Krishna, Paul Kellam, Stephen T. Reece, John S. Tregoning Source Type: research
The risks of death and hospitalizations associated with SARS-CoV-2 Omicron declined after lifting testing and quarantining measures
To the editor (Source: Journal of Infection)
Source: Journal of Infection - February 27, 2023 Category: Infectious Diseases Authors: Yamin Deng, Shasha Han, Jue Liu, Li Guo, Luzhao Feng, Yilan Liao, Zhixing Peng, Lili Ren, Weizhong Yang, Jianwei Wang Tags: Letter to the Editor Source Type: research
Intranasal immunisation with Outer Membrane Vesicles (OMV) protects against airway colonisation and systemic infection with Acinetobacter baumannii11Current addresses:KF UCL.
The multi-drug resistant bacteria Acinetobacter baumannii is a major cause of hospital associated infection; a vaccine could significantly reduce this burden. The aim was to develop a clinically relevant model of A. baumannii respiratory tract infection and to test the impact of different immunisation routes on protective immunity provided by an outer membrane vesicle (OMV) vaccine. (Source: Journal of Infection)
Source: Journal of Infection - February 27, 2023 Category: Infectious Diseases Authors: Sophie L. Higham, Stephen Baker, Katie E. Flight, Aisha Krishna, Paul Kellam, Stephen T. Reece, John S Tregoning Source Type: research
Sporothrix brasiliensis genotyping reveals numerous independent zoonotic introductions in Brazil
In the last decades, multiple fungal species have emerged, posing threats to public health.1 In this journal, we have reported the emergence of Candida auris in South America.2 Sporothrix brasiliensis constitutes another emerging fungal threat on the continent. This dimorphic fungus is the causative agent of human and animal sporotrichosis, and its first appearance was retrospectively identified in 1998 in Rio de Janeiro.3 Since then, there has been a staggering increase in the number of feline and human cases in various Brazilian States. (Source: Journal of Infection)
Source: Journal of Infection - February 23, 2023 Category: Infectious Diseases Authors: Bram Spruijtenburg, Amanda Bombassaro, Eelco F.J. Meijer, Anderson Messias Rodrigues, Maria Eduarda Grisolia, V ânia Aparecida Vicente, Flavio de Queiroz-Telles, Jacques F. Meis, Theun de Groot Tags: Letter to the Editor Source Type: research
Multiple mutations of IFITM3 are associated with COVID-19 susceptibilityregulation function of IFITM3 in COVID-19
Individuals have different symptoms of COVID-19 infection, which is not only caused by environmental and socioeconomic factors. Many studies have pointed out that it is closely related to genetic factors. We read with interest the publication by Li et al.1 reporting the relationship between Interferon-induced transmembrane protein 3 gene (IFIM3) polymorphisms and susceptibility and severity of COVID-19. Through a genotype study of 1989 samples, they found that the rs12252 of IFIM3 polymorphism was associated with COVID-19 susceptibility and severity, while rs34481144 was not. (Source: Journal of Infection)
Source: Journal of Infection - February 23, 2023 Category: Infectious Diseases Authors: Hongzhe Guo, Tianyi Zhao Tags: Letter to the Editor Source Type: research
