A decade of Campylobacter and Campylobacter bacteraemias in a district general hospital and the surrounding London and South East region, England
Campylobacter bacteraemia is a rare complication of the most common bacterial gastrointestinal infection but is associated with significant morbidity and mortality. There is limited data describing current trends in surveillance and antimicrobial resistance for the Campylobacter strains involved. At the Epsom and St Helier ’s University Hospital (ESTH), we noted a marked increase in Campylobacter bacteraemia infections in 2021. (Source: Journal of Infection)
Source: Journal of Infection - November 20, 2023 Category: Infectious Diseases Authors: Alice Graham, Lois Hawkins, Sooria Balasegaram, Subha Narasimhan, John Wain, John Clarke, Rohini Manuel Source Type: research
Machine learning-based colistin resistance marker screening and phenotype prediction in Escherichia coli from whole genome sequencing data
Dear Editor, (Source: Journal of Infection)
Source: Journal of Infection - November 20, 2023 Category: Infectious Diseases Authors: Yingxin Tian, Di Zhang, Fangyuan Chen, Guanhua Rao, Ying Zhang Tags: Letter to the Editor Source Type: research
Efficacy of SIGMAR1-based therapy in the early treatment of confirmed mild symptomatic COVID-19 patients
Dear Editor, (Source: Journal of Infection)
Source: Journal of Infection - November 20, 2023 Category: Infectious Diseases Authors: Santiago Grau, Jos é Miguel Vela, Alba Gurt, Jaime Barceló-Vidal, Fabiola Ojeda, Iago López, Laura Gómez-García, Mabel Loza, Elena Martín-García, Rafael Maldonado, Jordi Monfort, SIGMA Group Source Type: research
How do successive vaccinations and SARS-CoV-2 infections impact humoral immunity dynamics: an 18-month longitudinal study
Dear editor, (Source: Journal of Infection)
Source: Journal of Infection - November 17, 2023 Category: Infectious Diseases Authors: A.N. Diep, J. Schyns, C. Gourzones, E. Goffin, I. Papadopoulos, S. Moges, F. Minner, O. Ek, G. Bonhomme, M. Paridans, N. Gillain, E. Husson, M. Garigliany, G. Darcis, C. Saegerman, D. Desmecht, M. Guillaume, A.F. Donneau, F. Bureau, L. Gillet Source Type: research
Identification of a Novel HIV-1 Circulating Recombinant Form CRF157_A6C in Primorsky Territory, Russia
Dear editor, (Source: Journal of Infection)
Source: Journal of Infection - November 17, 2023 Category: Infectious Diseases Authors: Maksim R Halikov, Vasily E Ekushov, Alexei V Totmenin, Natalya M Gashnikova, Mariya E Antonets, Tatyana V Tregubchak, Lidiia P Skliar, Natalia P Solovyova, Irina S Gorelova, Svetlana N Beniova Source Type: research
Emergency Department point-of-care antiviral host response testing is accurate during periods of multiple respiratory virus co-circulation
FebriDx is a CE-marked, FDA-approved point-of-care test that detects the antiviral host response protein Myxovirus Resistance Protein A (MxA), in addition to C-reactive protein, using finger-prick blood. FebriDx MxA detection had a high negative predictive value for COVID-19 in symptomatic adults presenting to hospital in the first waves of the pandemic and was used subsequently as a ‘rule out’ triage tool in Emergency departments. The diagnostic accuracy of FebriDx MxA in the current context of co-circulation of influenza, SARS-CoV-2, and Respiratory Syncytial Virus (RSV), and in the era of COVID-19 vaccination, is un...
Source: Journal of Infection - November 15, 2023 Category: Infectious Diseases Authors: Nathan J Brendish, Cai Davis, Mary Chapman, Florina Borca, Daniel Waddington, Christopher Hill, Nicola White, Tristan W Clark Source Type: research
Impact of the COVID-19 pandemic on incidence and serotype distribution of pneumococcal meningitis – A prospective, nationwide cohort study from the Netherlands
Dear Editor (Source: Journal of Infection)
Source: Journal of Infection - November 8, 2023 Category: Infectious Diseases Authors: Fabian D Liechti, Merijn W Bijlsma, Matthijs C Brouwer, Nina M van Sorge, Diederik van de Beek Source Type: research
Estimating the prevalence of immunocompromising conditions and primary immunodeficiency disorders in the Chinese population
To the Editor: (Source: Journal of Infection)
Source: Journal of Infection - November 7, 2023 Category: Infectious Diseases Authors: Tao Chen, Hongni Wang, Hongbo Lin, Jianhua Liu, Chuanxi Fu Tags: Letter to the Editor Source Type: research
The Impact of Vaccination and SARS-CoV-2 Variants on the Virological Response to SARS-CoV-2 Infections during the Alpha, Delta, and Omicron waves in England
Vaccination status and the SARS-CoV-2 variant individuals are infected with are known to independently impact viral dynamics; however, little is known about the interaction of these two factors and how this impacts viral dynamics. Here we investigated how monovalent vaccination modified the time course and viral load of infections from different variants.Regression analyses were used to investigate the impact of vaccination on cycle threshold values and disease severity, and interval-censored survival analyses were used to investigate the impact of vaccination on duration of positivity. (Source: Journal of Infection)
Source: Journal of Infection - November 3, 2023 Category: Infectious Diseases Authors: Rachel Lunt, Catherine Quinot, Freja Kirsebom, Nick Andrews, Catriona Skarnes, Louise Letley, Donna Haskins, Catriona Angel, Skye Firminger, Kay Ratcliffe, Shelina Rajan, Angela Sherridan, Samreen Ijaz, Maria Zambon, Kevin Brown, Mary Ramsay, Jamie Lopez Source Type: research
Effectiveness of BNT162b2 mRNA vaccine third doses and previous infection in protecting against SARS-CoV-2 infections during the Delta and Omicron variant waves; the UK SIREN cohort study September 2021 to February 2022
Third doses of COVID-19 vaccines were widely deployed following primary vaccine course waning and emergence of the Omicron-variant. We investigated protection from third-dose vaccines and previous infection against SARS-CoV-2 infection during Delta-variant and Omicron-variant (BA.1& BA.2) waves in our frequently PCR-tested cohort of healthcare-workers.Relative effectiveness of BNT162b2 third doses and infection-acquired immunity was assessed by comparing the time to PCR-confirmed infection in boosted participants with those with waned dose-2 protection ( ≥254 days after dose-2), by primary series vaccination type. (Sourc...
Source: Journal of Infection - November 3, 2023 Category: Infectious Diseases Authors: Victoria J Hall, Ferdinando Insalata, Sarah Foulkes, Peter Kirwan, Dominic Sparkes, Ana Atti, Michelle Cole, Elen de Lacy, Lesley Price, Diane Corrigan, Colin S Brown, Jasmin Islam, The SIREN Study Group Source Type: research
Memory B cells anticipate SARS-CoV-2 variants through somatic hypermutation
Dear editor, (Source: Journal of Infection)
Source: Journal of Infection - October 30, 2023 Category: Infectious Diseases Authors: Matthias Bruhn, Maureen Obara, Abhishek Chiyyeadu, Bibiana Costa, Abdus Salam, Annett Ziegler, Inken Waltl, Andreas Pavlou, Agnes Bonifacius, Markus Hoffmann, Theresa Graalmann, Stefan P öhlmann, Britta Eiz-Vesper, Axel Schambach, Ulrich Kalinke Source Type: research
Did Saint Leonard suffer from Madura foot at the time of death? Infectious disease diagnosis by paleoproteotyping
Leonard was one of the most renowned saints during the Western Middle Ages. His biography, written in the 11th century, reports that he was a noble man converted to Christianity by Saint Remi, in 496, therefore at the same time as Clovis, one of the oldest kings of France. 1 Leonardo obtained from his sovereign the right to visit and possibly release the prisoners he deemed worthy of release, at any time. And it is because he freed a large number of prisoners that he became the patron saint of prisoners. (Source: Journal of Infection)
Source: Journal of Infection - October 30, 2023 Category: Infectious Diseases Authors: Philippe Charlier, Jean Armengaud Source Type: research
Exploring Immunity Debt: Dynamic Alterations in RSV Antibody Levels in Children Under 5 years During the COVID-19 Pandemic
Dear Editor, (Source: Journal of Infection)
Source: Journal of Infection - October 28, 2023 Category: Infectious Diseases Authors: Wujun Jiang, Lina Xu, Yuqing Wang, Chuangli Hao Tags: Letter to the Editor Source Type: research
Safety and immunogenicity of the COVID-19 mRNA vaccine CS-2034: A randomized, double-blind, dose-exploration, placebo-controlled multicenter Phase I clinical trial in healthy Chinese adults
At day 28 after the full vaccination, both the low-dose and the high-dose CS-2034 vaccine were able to induce the production of high titers of S-RBD IgG antibodies against the BA.1 strain. Adverse reactions in the low-dose and high-dose groups were mainly of severity grade 1 or 2, and no trial-limiting safety concerns were identified. These findings support further development of this vaccine. (Source: Journal of Infection)
Source: Journal of Infection - October 27, 2023 Category: Infectious Diseases Authors: Zhili Jin, Jingxuan Wu, Ying Wang, Tao Huang, Kexin Zhao, Jian Liu, Haomeng Wang, Tao Zhu, Jinbo Gou, Haitao Huang, Xiaofang Wu, Hang Yin, Jian Song, Ran Li, Jianxiong Zhang, Lijun Li, Jingcheng Chen, Xiao Li, Meijuan Zhang, JiangShuo Li, Mengyu Hou, Yuqi Source Type: research
Trends and predictions of tuberculosis notification in mainland China during and after the COVID-19 pandemic
Dear Editor, (Source: Journal of Infection)
Source: Journal of Infection - October 27, 2023 Category: Infectious Diseases Authors: Yueting Liu, Ruoyao Sun, Hongyin Zhang, Jinrong Huang, Meiru Chen, Yiqiang Zhan, Jianbang Xiang, Jianhui Yuan, Huachun Zou, Leonardo Martinez, Chongguang Yang Source Type: research
