IJERPH, Vol. 18, Pages 7602: Staphylococcus aureus Biofilm: Morphology, Genetics, Pathogenesis and Treatment Strategies
Rahman
Staphylococcus aureus is a nosocomial bacterium causing different infectious diseases, ranging from skin and soft tissue infections to more serious and life-threatening infections such as septicaemia. S. aureus forms a complex structure of extracellular polymeric biofilm that provides a fully secured and functional environment for the formation of microcolonies, their sustenance and recolonization of sessile cells after its dispersal. Staphylococcus aureus biofilm protects the cells against hostile conditions, i.e., changes in temperature, limitations or deprivation of nutrients and dehydration, and, more impo...
Source: International Journal of Environmental Research and Public Health - July 16, 2021 Category: Environmental Health Authors: Idrees Sawant Karodia Rahman Tags: Review Source Type: research
Case Report: Talaromyces marneffei Infection in a Chinese Child With a Complex Heterozygous CARD9 Mutation
Talaromyces marneffei (TM) infection is rarely seen in clinical practice, and its pathogenesis may be related to deficiency in antifungal immune function. Human caspase recruitment domain-containing protein 9 (CARD9) is a key molecule in fungal immune surveillance. There have been no previous case reports of TM infection in individuals with CARD9 gene mutations. Herein, we report the case of a 7-month-old Chinese boy who was admitted to our hospital with recurring cough and fever with a papular rash. A blood culture produced TM growth, which was confirmed by metagenomic next-generation sequencing. One of the patient’s si...
Source: Frontiers in Immunology - June 21, 2021 Category: Allergy & Immunology Source Type: research
Characterization of a bacterial strain Lactobacillus paracasei LP10266 recovered from an endocarditis patient in Shandong, China
Lactobacilli are often recognized as beneficial partners in human microbial environments. However, lactobacilli also cause diseases in human, e.g. infective endocarditis (IE), septicaemia, rheumatic vascular d... (Source: BMC Microbiology)
Source: BMC Microbiology - June 17, 2021 Category: Microbiology Authors: Qi Tang, Yingying Hao, Lu Wang, Chao Lu, Ming Li, Zaifeng Si, Xiaoben Wu and Zhiming Lu Tags: Research Source Type: research
Viruses, Vol. 13, Pages 1129: Evidence of Transcriptional Shutoff by Pathogenic Viral Haemorrhagic Septicaemia Virus in Rainbow Trout
van Aerle
The basis of pathogenicity of viral haemorrhagic septicaemia virus (VHSV) was analysed in the transcriptome of a rainbow trout cell line inoculated with pathogenic and non-pathogenic VHSV isolates. Although both VHSV isolates showed similar viral replication patterns, the number of differentially expressed genes was 42-fold higher in cells inoculated with the non-pathogenic VHSV at 3 h post inoculation (hpi). Infection with the non-pathogenic isolate resulted in Gene Ontologies (GO) enrichment of terms such as immune response, cytokine-mediated signalling pathway, regulation of translational initiation, unfol...
Source: Viruses - June 11, 2021 Category: Virology Authors: Irene Cano Eduarda M. Santos Karen Moore Audrey Farbos Ronny van Aerle Tags: Article Source Type: research
Comparison of super-mini versus mini percutaneous nephrolithotomy for the treatment of upper urinary tract stones in children: a single centre experience
ConclusionSMP is more effective than MPCNL for treating middle-sized upper urinary tract stones in children, and is associated with a shorter LOS and a higher tubeless rate. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - May 21, 2021 Category: Surgery Source Type: research
